Pimafukort - instructions for use, analogs, reviews and release forms (cream or ointment) of hormonal medication for the treatment of dermatoses complicated by candidiasis or thrush in adults, children (including infants) and during pregnancy. Composition
In this article you can get acquainted with the instructions for the use of a hormonal drug Pimafukort. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Pimafukort in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Pimafukorta in the presence of existing structural analogues.Use for the treatment of dermatoses complicated by candidiasis or thrush in adults, children, as well as during pregnancy and lactation. Composition of the preparation.
Pimafukort - Combined drug, which has antibacterial, antifungal and local anti-inflammatory effect due to the components included in its composition.
Natamycin belongs to the polyene antibiotics of macrolides, it has a fungicidal effect. It is active against yeast and yeast-like fungi (especially Candida spp. (Candida)). Dermatomycetes are less sensitive to natamycin.
Neomycin is a broad-spectrum antibiotic from the aminoglycoside group, is active against gram-positive bacteria: Staphylococcus spp. (staphylococcus), Enterococcus spp .; Gram-negative bacteria: Klebsiella spp. (Klebsiella), Proteus spp., Escherichia coli (E. coli) and others.
Hydrocortisone has an anti-inflammatory and vasoconstrictive effect. Eliminates inflammation and itching, accompanying various types of dermatoses.
Composition
Natamycin + Neomycin (in the form of sulfate) + Hydrocortisone micronized + auxiliary substances.
Pharmacokinetics
Natamycin and neomycin are almost not absorbed through intact skin and mucous membranes. It is possible to absorb neomycin through damaged skin, when applied to extensive wound and burn surfaces.
Through intact skin, 1 to 3% hydrocortisone is absorbed; with dermatitis the amount of absorbed hydrocortisone is increased 2 times, with infectious lesions of the skin can increase by 5 times.
In children, absorption of hydrocortisone through intact skin is higher than in adults. The degree of absorption of the drug in the systemic blood stream decreases with age.
Indications
- dermatoses that are amenable to glucocorticosteroid therapy (GCS), complicated by a secondary bacterial and / or fungal infection (especially caused by Candida spp.).
Release Forms
Cream for external use.
Ointment for external use.
There are no other medicinal forms, be they pills or candles.
Instructions for use and how to use them
For adults and children, the drug is applied to affected areas of the skin 2-4 times a day. Children should be applied to limited areas of the skin and do not use occlusive dressings.
The duration of treatment is determined individually, taking into account the nature of the disease, the course of treatment usually does not exceed 14 days. In the absence of improvement in children and adults after 14 days should consult a doctor.
The drug in the form of cream is recommended for the treatment of acute and subacute dermatoses.
The preparation in the form of ointment is intended for the therapy of subacute and chronic dermatoses, especially in the presence of severe dry skin, lichenification, or in cases where occlusive properties of the ointment are necessary.
Side effect
- itching;
- burning;
- redness or dryness of the skin;
- atrophy and thinning of the skin;
- telangiectasia;
- purpura;
- rosace-like and perioral dermatitis;
- slowing healing of wounds;
- depigmentation;
- hypertrichosis;
- withdrawal syndrome after discontinuation of treatment;
- contact dermatitis on neomycin;
- when external application of glucocorticosteroids (GCS) for a long time in large areas of the skin, or with the use of occlusive dressings, especially in children, the development of side effects due to the systemic effect of SCS - the symptoms of suppression of the adrenal cortex.
Contraindications
- lupus;
- cutaneous manifestations of syphilis;
- viral skin infections;
- dermal post-vaccination reactions;
- open wounds;
- ulcerative skin lesions;
- acne disease;
- rosacea;
- ichthyosis;
- anogenital itching;
- skin tumors;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
When applying Pimafukorta during pregnancy, it is necessary to take into account the theoretical risk of ototoxic effect of neomycin, therefore one should not apply the drug to extensive areas of the skin surface, it is impossible to apply the drug for a long time, to apply it for occlusive dressings.
Use in children
With caution should prescribe the drug to children under the age of 1 year.
In children, the drug should be administered under the supervision of a doctor. When applying the drug on large surfaces or under occlusive dressings, one must keep in mind the possibility of suppressing the function of the hypothalamic-pituitary-adrenal system.
Children should be applied to limited areas of the skin and do not use occlusive dressings.
special instructions
When applying Pimafukorta to the eyelids and periorbital area, there is a risk of increased intraocular pressure, the development of cataracts.
In the case of prolonged treatment, in the presence of wounds and ulcers, there is a theoretical risk of ototoxic and nephrotoxic action of neomycin.
If superinfection occurs or the fungal microflora develops excessively, the drug should be discontinued and appropriate measures taken.
With caution should apply the drug in systemic tuberculosis, in patients with indications in the history of the defeat of 9 pairs of cranial nerves aminoglycoside. If there is a perforation of the tympanic membrane and direct exposure of neomycin to the middle ear, there is a risk of ototoxic action.
Drug Interactions
Drug interaction of the drug Pimafukort is not described.
There is a cross-over hypersensitivity between neomycin and preparations of a similar chemical structure, for example, kanamycin, paromomycin, gentamycin, and cross-resistance between neomycin and other antibiotics of the aminoglycoside group.
Analogues of the drug Pimafukort
Pimafukort has no structural analogs for the active ingredient.
Analogues for the pharmacological group (glucocorticoids in combinations):
- Acriderm;
- Ambien;
- Aurobin;
- Belogent;
- Belosalik;
- Belosalik lotion;
- Bemilon;
- Betagenot;
- Betaderm;
- Betasal;
- Betnoveit;
- Garazon;
- Hydrocortisone Richter;
- Gyioxysone;
- Daivobet;
- Dexon;
- Dermozolone;
- Diprosalic;
- Doloproct;
- Candibiotics;
- Candide B;
- Candiderm;
- Canison plus;
- Cortomycetin;
- Lorinden;
- Lotriderm;
- Maxitrol;
- Mikozolone;
- Nefluen;
- Oxycort;
- Polidex;
- Polcortolon TS;
- Proctosedil;
- Rederm;
- Sinalar;
- Skinlight;
- Sofradex;
- Sulfodecorthem;
- Supirocin B;
- Tebridex;
- Tebrone;
- Triderm;
- Ultraproject;
- Flukort;
- Flucinar;
- Foster;
- Fucidin;
- Fucicort;
- Elokom.
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