Ubidekarenon - instructions for use, reviews, analogs and forms of release (drops 3%, tablets 50 mg, capsules 30 mg) of a drug for the treatment of coronary heart disease and myocardial infarction in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Ubidecarenone. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Ubidekarenone in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Ubidecarenone in the presence of existing structural analogs.Use for the treatment of coronary heart disease, myocardial infarction in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Ubidecarenone antioxidant. Carries ions of hydrogen, is a component of the respiratory chain. Increases the blood levels of prostacyclin and reduces - thromboxane. Has cardiotonic, cardioprotective, adaptogenic and immunostimulating action. Promotes the restoration of physical performance, increases the ability of the body to adapt to increased stress, stress and hypoxia.

Composition

Ubidecarenone + auxiliary substances.

Pharmacokinetics

Experimental studies in animals have shown that after ingestion the drug is rapidly absorbed, the maximum concentration in plasma is achieved 1 hour after admission. Bioavailability of the drug is 20%. Half-life is 2 hours. The drug is excreted in the urine in an unchanged form and in the form of metabolites.

Indications

• ischemic heart disease or ischemic heart disease;
• angina pectoris;
• myocardial infarction (period of restorative therapy);
• chronic heart failure;
• arterial hypertension (high blood pressure);
• the period of preparation for cardiac surgery (coronary artery bypass grafting, with heart defects);
• prevention and as part of a comprehensive therapy for migraine;
• the need to improve physical performance and adapt to the increased workload of athletes.

Forms of release

Drops for ingestion 3% (as part of the preparation Kudesan).

Tablets chewing 50 mg (as part of the drug Valeocor Q10).

Capsules 30 mg (in the composition of the drug Kudevita).

Instructions for use and dosing regimen

Is taken orally, regardless of food intake. With ischemic heart disease - 30-45 mg 3 times a day. The course of treatment is 1-3 months. Repeat courses are possible. Athletes in the preparatory and competitive period - 45-75 mg 2-3 times a day, for 7-10 days.

Side effect

• nausea;
• vomiting;
• diarrhea;
• pain in epigastrium;
• allergic reactions;
• Reduction of blood pressure;
• bradycardia.

Contraindications

• increased sensitivity to ubdecarenone;
• severe bradycardia (heart rate less than 50 beats per minute);
• acute glomerulonephritis;
• peptic ulcer of the stomach and duodenum in the stageexacerbations;
• pregnancy and lactation.

Carefully

• arterial hypotension.

Application in pregnancy and lactation

The drug Ubidekarenon is not recommended for use during pregnancy and lactation, as strictly controlled clinical trials of safety of the drug in pregnant and lactating women were not conducted.

Use in children

Contraindicated in children under 1 year.

special instructions

Use with caution in arterial hypotension.

Influence on ability to drive vehicles and work with mechanisms

There is no evidence of adverse effects of the drug on the ability to drive vehicles and mechanisms.

Drug Interactions

The simultaneous use of lipid-lowering drugs (statins, fibrates), beta-blockers (atenolol, metoprolol, propranolol), tricyclic antidepressants can lead to a decrease in the concentration of ubidecarenone in the blood plasma.

Ubidekarenone can potentiate the action of diltiazem, metoprolol, Enalapril and nitrates, and also reduce the effect of warfarin.

Analogues of the drug Ubidecarenone

Structural analogs for the active substance:

• Qudesan;
• Kudevita;
• Valeocorus Q10;
• Kudesan for children;
• ALL Kew.

Analogues for the pharmacological group (antihypoxants and antioxidants):

• Actovegin;
• Angiosyl retard;
• Antistene CF;
• Astrox;
• Vixipine;
• Vitanam;
• Hypoxen;
• Histochrome;
• Glathion;
• Deprenorm;
• Dihydroquercetin;
• Dimephosphone;
• Cardiocipine;
• Carditrim;
• Carnitine;
• Carniffite;
• Confusamine;
• Kudevita;
• Qudesan;
• Laproth;
• Levocarnitine;
• Lemontar;
• Medarum 20;
• Medomexi;
• Mexico 6;
• Mexidant;
• Mexidol;
• Mexicor;
• Mexiprim;
• Mexicin;
• Methyl ethylpyridinol;
• Metostabil;
• Mitomin;
• Sodium oxybate;
• Sodium oxybutyrate;
• Neurocardia;
• Neurox;
• Neurolephone;
• Oxyl;
• Octolipen;
• Oliphen;
• Polythion;
• Predizin;
• Preductal;
• Precardard;
• Proinin;
• Proxipin;
• Prophylactin C;
• Rexod;
• Romekor;
• Solcoseryl;
• Tiogamma;
• Tiotriazolin;
• Trekrezan;
• Tridoukard;
• Trimectal;
• Trimet;
• Trimetazidine;
• Trimitard;
• Emoxibel;
• Yantavit.

Doctor's Feedbacktherapist

Coenzyme Ubihinon, also Ubidekarenon, prevents the aging of cells. In addition to cardiology, it is used in the therapy of chronic fatigue, asthenia, vegetovascular dystonia and even is part of some wrinkle creams.If before it was only a biologically active additive (BAD), it is now declared as a full-fledged drug. On the territory of the former CIS is often prescribed in parallel with the main therapy for extrasystoles, chronic heart failure, atherosclerosis. Even if Ubidekarenon does not bring visible improvements, then the harm from it is very unlikely. However, in the US, this drug is not used, because its effectiveness is not proven.

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