Sprax - instructions for use, analogs, reviews and release forms (capsules or tablets 200 mg) drugs for the treatment of irritable bowel syndrome, spasms, colic, dyspepsia in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Sparex. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Sparex in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Sparex in the presence of existing structural analogs. Use for the treatment of irritable bowel syndrome, spasms, colic, dyspepsia in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Sparex - antispasmodic myotropic action, has a direct effect on the smooth muscles of the gastrointestinal tract (mainly the large intestine). Eliminates spasm without affecting normal intestinal motility. Inhibits phosphodiesterase. Stabilizes the level of cyclic adenosine monophosphoric acid. Does not possess anticholinergic action.

Composition

Mebeverine hydrochloride + excipients.

Pharmacokinetics

When ingested, it undergoes pre-systemic hydrolysis and is not detected in the plasma. Metabolised in the liver to veratric acid and mebeverin alcohol. It is excreted mainly by the kidneys in the form of metabolites, in small amounts - by bile. Mebeverine capsules have a prolonged release property. Even after repeated administration, there is no significant cumulation.

Indications

In adults:

• spasm of the digestive tract (including caused by organic disease);
• intestinal colic;
• biliary colic;
• irritable bowel syndrome.

Children older than 12 years:

• Functional disorders of the gastrointestinal tract, accompanied by pain in the abdomen.

Forms of release

Capsules of prolonged action of 200 mg (sometimes mistakenly called tablets).

Instructions for use and dosing regimen

Inside adults and children over 12 years of age, 1 capsule (200 mg) 2 times a day for 20 minutes before meals (morning and evening). Swallow whole with water.

Side effect

• dizziness;
• headache;
• diarrhea, constipation;
• hives;
• angioedema;
• swelling of the face;
• exanthema.

Contraindications

• hypersensitivity;
• porphyria;
• pregnancy;
• children under 12 years of age (due to insufficient data on effectiveness and safety).

Application in pregnancy and lactation

Sprax is contraindicated during pregnancy.

When lactating (breast-feeding), use caution when using this medication. When used in therapeutic doses, mebeverin does not penetrate into breast milk.

Use in children

Contraindicated use of the drug for children under the age of 12 years (due to insufficient data on effectiveness and safety).

special instructions

The drug is released by prescription.

Impact on the ability to drive vehicles and manage mechanisms

During the treatment period it is necessary to refrain from driving motor vehicles and practicing potentially dangerous activities,requiring increased concentration of attention and speed of psychomotor reactions.

Drug Interactions

Not noted.

Analogs of the drug Sparex

Structural analogs for the active substance:

• Duspatalin;
• Dutan;
• Mebeverin;
• Mebeverine hydrochloride;
• Mebespalin retard;
• Niaspam.

Analogues on the curative effect (remedies for the treatment of irritable bowel syndrome):

• Bactistatin;
• Betamax;
• Galidor;
• Guttasil;
• Dicetel;
• Drotaverine;
• Duspatalin;
• Irmalax (dietary fiber with vitamin C and citrus flavor);
• Colorado;
• Lactofiltrum;
• Meteopazmil;
• Mukofalk;
• Neobutin;
• Neointestopan;
• But the spine;
• But the forte;
• NovoPassit;
• Novobispol;
• Papaverine;
• Probiophore;
• Spasmonet;
• Spasmonet forte;
• Spacock;
• Trimedate;
• Ulkavis;
• Phytomycyl Dieth formula;
• Eglek;
• Enterosan.

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