Beloderm - instructions for use, analogs, reviews and release forms (ointment and cream 0.05%, spray for external use Express) of a drug for the treatment of neurodermatitis, eczema, psoriasis in adults, children and pregnancy. Composition
In this article, you can read the instructions for using the drug Beloderm. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Beloderm in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Beloderm analogues in the presence of existing structural analogues.Use for the treatment of neurodermatitis, eczema, psoriasis, atopy in adults, children, as well as during pregnancy and lactation. Composition of the hormonal drug.
Beloderm - Glucocorticosteroid agent (GCS) for external use.
Suppresses the function of white blood cells and tissue macrophages. Limits the migration of leukocytes to the area of inflammation. Violates the ability of macrophages to phagocytosis, as well as to the formation of interleukin-1. Promotes the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the area of inflammation. Reduces the permeability of capillaries due to the release of histamine. Suppresses the activity of fibroblasts and the formation of collagen. Has anti-inflammatory, antipruritic, anti-allergic, vasoconstrictive, antiexudative and antiproliferative action.
When applied to the skin surface, the drug has a quick and powerful effect in the inflammation focus, reducing the severity of objective symptoms (erythema, edema, lichenification) and subjective sensations (itching, irritation, pain).
Composition
Betamethasone dipropionate + auxiliary substances.
Pharmacokinetics
Binding to plasma proteins is about 64%. Metabolised in the liver. Metabolites are excreted mainly by the kidneys, a small part - with bile. When absorbed through the skin, Betamethasone is characterized by similar pharmacokinetic properties, both with external and with systemic application. Systemic absorption after external application is 12-14%. For local and external use with intact skin, absorption may be negligible. The presence of an inflammatory process, as well as the use of an occlusive dressing, can increase the amount of absorption.
Indications
The conditions under which effective therapy with topical GCS, including:
- atopic dermatitis;
- neurodermatitis;
- allergic contact dermatitis;
- eczema (various forms);
- contact dermatitis (including professional);
- non-allergic dermatitis (including sun and radiation dermatitis);
- reactions to insect bites;
- psoriasis;
- bullous dermatoses;
- discoid lupus erythematosus;
- red flat lichen;
- exudative erythema multiforme;
- itching of various etiologies.
Forms of release
Cream for external use 0,05%.
Ointment for external use 0,05%.
Spray for external use 0,05%.
Instructions for use and how to use them
Cream or ointment
The drug is intended for external use only.
Cream or ointment for external use is applied to the affected area of the skin with a thin layer 2 times a day, lightly rubbing. On sites with denser skin (for example, elbows, palms and feet), as well as places from which the drug is easily erased, the drug can be applied more often. The duration of continuous treatment is usually not more than 4 weeks.
For the prevention of relapse in the treatment of chronic diseases, therapy should continue for some time after the disappearance of all symptoms.
During the year, repeated courses of therapy are possible.
The cream for external use is used for acute therapy, including. wetting skin lesions.
Ointment for external use is intended for the therapy of subacute and chronic dermatoses, incl. dry, lichenic and flaky lesions, or in cases where the occlusive effect of the ointment is necessary.
Spray
For external application, apply a thin layer on the affected area of the skin 2-6 times a day before clinical improvement, then apply 1-2 times a day.When using betamethasone in children, as well as in patients with facial lesions, the course of treatment should not exceed 5 days.
Side effect
- hypersensitivity reactions (itching, burning, hyperemia);
- acne-like changes (the appearance of acne or acne);
- hypopigmentation;
- stria;
- skin atrophy;
- hypertrichosis;
- telangiectasia;
- secondary skin infections.
Contraindications
- lupus;
- cutaneous manifestations of syphilis;
- chickenpox;
- viral, bacterial and fungal skin infections;
- dermal post-vaccination reactions;
- open wounds;
- trophic ulcers;
- rosacea;
- Acne vulgaris;
- tumors of the skin and subcutaneous structures;
- children up to 6 months;
- increased sensitivity to betamethasone or to any of the auxiliary components of the drug.
Application in pregnancy and lactation
The use of Beloderm in pregnant women is allowed in cases where the intended use for the mother exceeds the risk to the fetus. In such cases, the use of the drug should be short and limited to small areas of skin.
During breastfeeding, the drug can be used according to strict indications, but the drug should not be applied to the skin of the breast before feeding.
Use in children
The drug can be administered to children from 6 months (including infants and newborns) with caution and for as short a time as possible. Do not apply the drug under the bandages and, especially under plasticized diapers, because this increases the absorption of the drug and increases the risk of side effects.
special instructions
It is not recommended to use the product on the face for a long time, since possible the development of rosacea, perioral dermatitis and acne.
The drug should not be used in the eye area, due to the likelihood of the drug getting on the mucous membrane, which can contribute to the development of cataracts, glaucoma, fungal infections of the eye and exacerbation of herpetic infection.
Some areas of the body, such as axillary cavities, inguinal folds where there is natural occlusion, are more susceptible to the risk of streaking, so the use of the drug in these areas of the skin should be short-lived.
With the development of fungal or bacterial infection on the skin, it is necessary to use an additional antibacterial or antifungal agent.
When developing a hypersensitivity reaction or adverse reactions, the drug should be discarded.
Impact on the ability to drive vehicles and manage mechanisms
Data on the adverse effect of the drug Beloderm on the ability to drive vehicles and mechanisms is not available.
Drug Interactions
With simultaneous use with cardiac glycosides, their action is enhanced; with diuretics - the excretion of potassium increases; with hypoglycemic drugs, oral anticoagulants - weakening of their action; with non-steroidal anti-inflammatory drugs (NSAIDs) - the risk of erosive and ulcerative lesions and bleeding from the gastrointestinal tract increases.
Analogues of the drug Beloderm
Structural analogs for the active substance:
- Acriderm;
- Beloderm Express;
- Betazon;
- Betamethasone;
- Betamethasone valerate;
- Betamethasone dipropionate;
- Betaspan Depot;
- Betliben;
- Betnoveit;
- Diprospan;
- Kuterid;
- Flosteron;
- Celestoderm B;
- Celeston.
Analogues on the curative effect (remedies for treating red flat lichen):
- Belogent;
- Belosalik;
- Belosalik lotion;
- Deperzolone;
- Dermovate;
- Diprogen;
- Diprosalic;
- Kutiweit;
- Lorinden;
- Neotigazone;
- Oksoralen;
- Rederm;
- Sinalar;
- The Synoderm;
- Thiamine chloride;
- Ultralan;
- Phenoxymethylpenicillin;
- Flukort;
- Flucinar;
- Fluorocort;
- Eikonol;
- Elokom;
- Elok Lotion.
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