Penzital - instructions for use, reviews, analogs and formulations (tablets) of the drug for the treatment of pancreatitis, impaired digestion and improved digestion of food in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Penzital. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Penzital in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Penzital with available structural analogues. Use to treat pancreatitis, impaired digestion and improve digestion of food in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Penzital - Enzyme preparation.Compensates the insufficiency of the exocrine function of the pancreas. Enzymes included in the Pancreatin (lipase, alpha-amylase, proteases (trypsin, chymotrypsin)) promote the breakdown of proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides. The drug improves the functional state of the gastrointestinal tract, normalizes the digestive process.

Trypsin inhibits the stimulated secretion of the pancreas, has analgesic effect.

Pancreatic enzymes are released from the dosage form in the alkaline medium of the small intestine (as the tablet is coated with an enteric coating protecting the components of the drug from the effects of gastric juice).

The maximum enzymatic activity is observed 30-45 minutes after ingestion.

Composition

Pancreatin + auxiliary substances.

Indications

• replacement therapy with exocrine pancreatic insufficiency (chronic pancreatitis, post-pancreatitis, after irradiation, dyspepsia, Remkheld syndrome (gastrocardial syndrome), cystic fibrosis, flatulence, diarrhea of ​​non-infectious genesis);
• violation of the assimilation of food (state after resection of the stomach or small intestine);
• to improve the digestion of food for people with normal gastrointestinal function in the event of errors in nutrition (eating fatty foods, eating irregularly, taking large amounts of food) and in cases of malfunctioning, sedentary lifestyle, prolonged immobilization;
• Preparation for X-ray examination and ultrasound of the abdominal cavity organs.

Forms of release

Tablets, covered with enteric coating.

Instructions for use and dosing regimen

The drug should be taken orally during or after a meal, the tablets are not chewed and washed with non-alkaline liquid (water, fruit juices).

The dose is determined individually depending on the degree of digestion disorders.

Adults prescribe 1-2 tablets 3 times a day.

For children, the dose is determined individually.

Duration of treatment can vary from several days (if the digestive process is disturbed due to inaccuracies in the diet) to several months and years (if necessary, permanent replacement therapy).

Side effect

• diarrhea, constipation;
• feeling of discomfort in the stomach;
• nausea;
• allergic reactions;
• possibly the development of strictures (fibrous colonopathy) in the ileocecal region in the ascending colon;
• the occurrence of perianal irritation and irritation of the oral mucosa in children.

Contraindications

• acute pancreatitis;
• exacerbation of chronic pancreatitis;
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The safety of Penzital in pregnancy is not well understood. Therefore, the use of the drug is possible in those cases when the expected benefit for the mother exceeds the potential risk to the fetus.

Use in children

For children, the dose is determined individually.

special instructions

Cystic fibrosis does not recommend the use of the drug in high doses because of the risk of developing fibrous colonopathy.

The dose of the drug should be adequate to the number of enzymes that is needed to absorb fat, taking into account the quality and quantity of food consumed.

With prolonged use of Penzital simultaneously, iron preparations should be prescribed.

Drug Interactions

With the simultaneous use of Penzital with iron preparations, it is possible to reduce the absorption of the latter.

Simultaneous use of antacid preparations containing calcium carbonate and / or magnesium hydroxide, reduces the effectiveness of pancreatin.

Analogues of the drug Penzital

Structural analogs for the active substance:

• Gastenorm forte;
• Creon;
• Mezim;
• Mezim forte;
• Mikrazim;
• Pangrol;
• PanziKam;
• Panzim Forte;
• Panzinorm;
• Panzinorm forte;
• Pancreatym;
• Pancreatin;
• Pancreatin forte;
• Pancrelipase;
• Pantcitrate;
• Festal N;
• Enzistal P;
• Hermitage.

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