Texamen - instructions for use, reviews, analogs and forms of release (20 mg tablets, injections in injections) for arthritis, neuralgia and myalgia in adults, children and pregnancy. Composition and alcohol
In this article, you can read the instructions for using the drug The Texman. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of experts on the use of Texamena in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Texamena in the presence of existing structural analogues. Use for the treatment of arthritis, neuralgia and myalgia in adults, children, as well as during pregnancy and lactation.Composition and interaction of the drug with alcohol.
The Texman - a non-steroidal anti-inflammatory drug of the class of oxicams. Has a powerful analgesic and anti-inflammatory effect, antipyretic effect is less pronounced. The mechanism of action is based on inhibition of the activity of isoenzymes COX-1 and COX-2, as a result of which the synthesis of prostaglandins in the inflammatory focus and other body tissues is reduced. In addition, tenoxicam (the active substance of the drug Texamen) reduces the accumulation of leukocytes in the focus of inflammation. A distinctive feature of tenoxicam is a long duration of action.
Composition
Tenoxicam + auxiliary substances.
Indications
- osteoarthritis;
- myalgia;
- neuralgia;
- osteochondrosis;
- gout;
- radicular syndrome.
Forms of release
The tablets covered with a cover of 20 mg.
Lyophilizate for the preparation of solution for intravenous and intramuscular injection (injections in ampoules for injections).
Instructions for use and dosing regimen
For oral administration, intravenously, intramuscularly or rectally, the dose is 20 mg once daily. In the case of acute processes, the duration of the course of treatment is 7-14 days.Parenteral is used when there is no possibility of oral administration, in dosages corresponding to oral use.
Side effect
- erosive and ulcerative lesions of the gastrointestinal tract;
- diarrhea;
- stomach ache;
- nausea, vomiting;
- flatulence;
- gastritis;
- esophagitis;
- bleeding from erosions, ulcers, as well as rectal and hemorrhoidal hemorrhages, which is a consequence of inhibition of thromboxane A2 synthesis;
- anemia, thrombocytopenia, leukopenia, eosinophilia;
- headache;
- dizziness;
- tremor;
- excitation;
- insomnia or drowsiness;
- irritation;
- puffiness of the eyelids (with normal results of ophthalmoscopy);
- Lyell's syndrome;
- Stevens-Johnson syndrome;
- hives;
- itching;
- alopecia;
- photosensitization;
- changes in nails;
- netrombotsitopenicheskaya purpura.
Contraindications
- erosive and ulcerative lesions of the gastrointestinal tract in the phase of exacerbation;
- indications in an anamnesis for peptic ulcer of the stomach and duodenum;
- bleeding from the digestive tract;
- pregnancy;
- lactation (breastfeeding);
- increased sensitivity to tenoxicam and other non-steroidal anti-inflammatory drugs (NSAIDs).
Application in pregnancy and lactation
Texamen is contraindicated in pregnancy and lactation.
Due to the use of tenoxicam during pregnancy, lengthening of pregnancy, delay in labor and weak labor activity (as a result of a decrease in the synthesis of prostaglandins stimulating the rhythmic contractile activity of the myometrium) is possible.
Use in children
Clinical data are absent.
special instructions
When applying Texamena, you should carefully monitor the function of the gastrointestinal tract. If the first signs of ulcerogenesis or gastrointestinal bleeding are discovered, tenoxicam should be immediately withdrawn.
Use with caution in patients with impaired renal function (including those caused by diabetes mellitus). Prostaglandins synthesized in the kidneys regulate the volumetric flow in the renal parenchyma. In case of violation of prostaglandin synthesis under the influence Teksamena may develop a decrease in renal blood flow, which leads to the phenomena of renal failure, as well as interstitial nephritis, glomerulonephritis, papillary necrosis and the nephrotic syndrome.Especially caution should be used tenoxicam on the background of treatment with diuretics or potentially nephrotoxic drugs.
For renal failure, patients with QC greater than 25 ml / min require careful monitoring of the physician without correction of the dosing regimen. Clinical data on the use of tenoxicam in patients with SC less than 25 ml / min are limited.
Use with caution in patients with impaired hepatic function. If against the background of the use of tenoxicam there is an excessive increase in the level of transaminases, which persists during therapy, then tenoxicam should be discontinued.
Tenoxicam is capable of retaining potassium, sodium, and water ions. In this regard, tenoxicum can worsen the course of hypertension or heart failure.
Texamen reduces platelet aggregation and increases bleeding time, which should be borne in mind in upcoming surgical interventions.
It is not recommended to drink with alcohol (increased risk of bleeding GIT).
It is not recommended to use tenoxicam in combination with salicylates.
Drug Interactions
In connection with the fact that Texamen is able to cause a decrease in lithium excretion, patients who receive lithium preparations may experience intoxication.
Analogs of the medicament Texamen
Structural analogs for the active substance:
- Artoxane;
- Texared;
- Tenikam;
- Tenoktil;
- Tilcotyl;
- Tobitil.
Analogues on the curative effect (means for the treatment of arthritis):
- Azathioprine;
- Actasulide;
- Amelotex;
- Arava;
- Arkoxy;
- Arthrosylen;
- Aertal;
- Wobenzym;
- Voltaren;
- Decortin;
- Dexazone;
- Dexalgin;
- Dicloran;
- Diclofenac;
- Dimexide;
- Diprospan;
- Dolgit;
- Ibuprofen;
- Indomethacin;
- Ketonal;
- Ketoprofen;
- Xsefokam;
- MabThera;
- Meloksam;
- Meloksikam;
- Movalis;
- Nyz;
- Naklofen;
- Nalgezin;
- Naproxen;
- Panavir;
- Plaquenil;
- Polyoxidonium;
- Polcortolone;
- Prednisolone;
- Feloran;
- Flamax;
- Cyclosporin;
- Эветрекс;
- Endoxane;
- Eralfon.
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