Piperazine - instructions for use, analogs, testimonials and release forms (200 mg tablets and 500 mg Adipate) for the treatment of ascaridosis, enterobiasis and other worms in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Piperazine. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Piperazine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of piperazine in the presence of existing structural analogs. Use to treat ascariasis, enterobiasis and other worms in adults, children, as well as during pregnancy and lactation.Composition of the preparation.

Piperazine - anthelminthic agent. Has a paralyzing effect on nematodes, disrupting the function of their neuromuscular system.

Composition

Piperazine adipate + auxiliary substances.

Indications

• ascaridosis;
• enterobiosis.

Forms of release

Tablets 200 mg and 500 mg of adipate.

Instructions for use and dosage

With ascariasis, take 2 consecutive days 2 times a day for 1 hour before or 0.5-1 hours after meals in the following doses:

Adults - a single dose of 1.5-2 g.

Children:

• 13-15 years - a single dose of 1.5 g;
• 9-12 years - a single dose of 1 g;
• 6-8 years - a single dose of 750 mg;
• 4-5 years - single dose of 500 mg;
• 2-3 years - single dose of 300 mg;
• up to 1 year - a single dose of 200 mg.

It is also possible to use for one day: once from 400 mg to 4 g (depending on the age) or 2 times from 200 mg to 2 g.

When enterobiosis is used in the same doses for 5 consecutive days, 1-3 treatment cycles are performed with a 7-day break. In breaks between cycles it is recommended to prescribe an enema for the night (to remove pinworm from the rectum): adults - from 4-5 glasses of water, children - from 1-3 glasses of water (with the addition of sodium bicarbonate 1/2 teaspoon per glass of water) .

Side effect

• nausea;
• stomach ache;
• transient headache;
• neurotoxic complications;
• tremor;
• muscle weakness.

Contraindications

• organic diseases of the central nervous system;
• hypersensitivity to piperazine adipate.

Application in pregnancy and lactation

It is not contraindicated in pregnancy and breastfeeding.

Use in children

It is possible to use the drug in children at age dosages indicated above.

special instructions

The use of piperazine does not require the preliminary preparation of patients and the appointment of a special diet. Laxatives are prescribed only if prone to constipation (on the days of piperazine in the evening). In the treatment of enterobiosis, strict adherence to the hygiene regime is necessary.

Drug Interactions

With the combined use of piperazine increases the severity of extrapyramidal disorders caused by chlorpromazine.

Simultaneous use with pyrantel is not recommended.

Analogues of the drug Piperazine

Structural analogs for the active substance:

• Piperazine adipate.

Analogues on the curative effect (anthelmintics):

• Biltricide;
• Vermox;
• Worming;
• Gelmodol BM;
• Helmintox;
• Decaris;
• Mebendazole;
• Medamin;
• Nemosol;
• Nemocide;
• Pirantel;
• Pirantela pamoat;
• Piervinium;
• Sanoxal;
• Telmox 100.

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