Noopept - instructions for use, reviews, analogs and form of release (10 mg tablets) of the nootropic drug for the treatment of memory disorders and attention, the effects of chmt in adults, children and pregnancy. Composition and alcohol
In this article, you can read the instructions for using the drug Noopept. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Noopept in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Noopept if there are existing structural analogues. Use to treat memory impairment and attention, the effects of chmt in adults, children,as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.
Noopept - Nootropic preparation. Has nootropic and neuroprotective action. Improves learning ability and memory by acting on all phases of the process: initial information processing, consolidation, extraction. Prevents the development of amnesia caused by electric shock, blockade of central cholinergic structures, glutamatergic receptor systems, deprivation of the paradoxical phase of sleep.
The neuroprotective effect of the drug is manifested in increasing the resistance of brain tissue to damaging effects (trauma, hypoxia, electroconvulsive or toxic effect) and weakening the degree of damage to brain neurons. The drug reduces the volume of the focus on the thrombotic stroke model and prevents the death of neurons in the tissue culture of the cerebral cortex and cerebellum, subjected to the action of neurotoxic concentrations of glutamate, free radical oxygen.
Noopept has an antioxidant effect, blocks potential-dependent calcium channels of neurons, weakening the neurotoxic effect of excess calcium.Improves rheological properties of blood, possessing antiaggregant, fibrinolytic, anticoagulant properties.
Nootropic action of the drug is associated with the formation of cycloprolylglycine, similar in structure to the endogenous cyclic dipeptide, which has antiamnestic activity, as well as the presence of cholinopositive action.
Noopept increases the amplitude of the transcallosal response, facilitating associative connections between the cerebral hemispheres at the level of the cortical structures.
Promotes the restoration of memory and other cognitive functions, disrupted as a result of damaging effects - brain trauma, local and global ischemia, prenatal injuries (alcohol, hypoxia).
The therapeutic effect of the drug in patients with organic diseases of the central nervous system manifests itself with 5-7 days of treatment. Initially, anxiolytic and mild stimulating effects are realized, manifested in the reduction or disappearance of anxiety, increased irritability, affective lability, and sleep disturbances. After 14-20 days of therapy, the positive effect of the drug on cognitive functions, attention and memory parameters is revealed.
Noopept has vegetative normalizing effect, it helps to reduce headaches, orthostatic disorders, tachycardia.
With withdrawal of the drug, there is no withdrawal syndrome.
Does not have a damaging effect on internal organs, does not lead to a change in the cellular composition of the blood and biochemical indicators of blood and urine; does not have an immunotoxic, teratogenic effect, does not show mutagenic properties. Does not cause drug dependence.
Composition
Ethyl ester of N-phenylacetyl-L-prolylglycine (noopept) + auxiliary substances.
Pharmacokinetics
It is absorbed from the digestive tract. In unchanged form is absorbed into the systemic circulation. Bioavailability is 99.7%. Penetrates through the blood-brain barrier (BBB). It is determined in the brain at higher concentrations than in the blood. The drug is partially preserved unchanged, partially metabolized with the formation of phenylacetic acid, phenylacetylproline and cycloprolylglycine. Do not cum in the body.
Indications
Violations of memory, attention, other cognitive functions and emotionally-labile disorders (including in elderly patients) with:
- consequences of traumatic brain injury;
- postcommunism syndrome;
- insufficiency of cerebral circulation (encephalopathies of various origins);
- asthenic disorders;
- Other states with signs of a decline in intellectual productivity.
Forms of release
Tablets 10 mg.
Instructions for use and dosing regimen
Noopept is used inside, after eating.
The drug is prescribed in an initial dose of 20 mg - 10 mg in 2 divided doses (morning and afternoon). With insufficient effectiveness of therapy and with good tolerability of the drug, the dose is increased to 30 mg - 10 mg in 3 divided doses during the day.
Do not take the drug later than 18 h.
The duration of the course treatment is 1.5-3 months. Repeated treatment if necessary can be done after 1 month.
Side effect
- allergic reactions;
- in patients with arterial hypertension, mostly severe, against the background of taking the drug, there may be a rise in blood pressure.
Contraindications
- pregnancy;
- lactation period (breastfeeding);
- children and adolescents under 18;
- hypersensitivity to the components of the drug;
- deficiency of lactase, lactose intolerance, glucose / galactose malabsorption syndrome;
- severe liver dysfunction;
- severe renal dysfunction.
Application in pregnancy and lactation
The drug is contraindicated for use in pregnancy and lactation (breastfeeding).
There is no teratogenic effect of the drug.
Use in children
Contraindicated in children and adolescents under the age of 18 years.
special instructions
The patient should be informed that if it is necessary to increase the dose of the drug (up to 30 mg per day), with prolonged use, as well as with simultaneous use with other drugs, the appearance of adverse reactions or worsening of the condition, you should consult a doctor.
Impact on the ability to drive vehicles and manage mechanisms
Noopept does not affect the ability to manage machinery and vehicles.
Drug Interactions
Noope interaction is established with alcohol, hypnotics, hypotensive drugs and psychostimulating drugs.
Analogs of the drug Hoenopt
Noopept has no structural analogs for the active substance.
Analogues for the pharmacological group (nootropics):
- Amylonosar;
- Aminalon;
- Anvifen;
- Vinpotropil;
- Gamalon;
- Ginkyo;
- Gliatilin;
- Glycine;
- Gopantam;
- Idebenon;
- Intelland;
- Combbitropyl;
- Cortexin;
- Cortexin for children;
- Coenzyme Q10 with Ginkgo;
- Lucetsam;
- Mexipridol;
- Mexiprim;
- Mexicin;
- Memotropized;
- Nootropil;
- Noocetam;
- Omaron;
- Pantogam;
- Pantokaltsin;
- Pikamilon;
- Piraben;
- Piracesine;
- Piracetam;
- Semax;
- Stamine;
- Tenoten;
- Tenoten for children;
- Thiocetam;
- Fezam;
- Fenibut;
- Phenotropil;
- Holilitil;
- Ceraxon;
- Cerebrial;
- Cerebrosolate;
- Cerebrolysin;
- Cerepro;
- Energol;
- Encephabol;
- The escotrope.
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