Retabolil - instructions for use, analogs, reviews and release forms (injections in ampoules for injections of 50 mg) anabolic drugs for the treatment of cachexia and muscular dystrophy in adults, children and in pregnancy

In this article, you can read the instructions for using the drug Retabolil. There are reviews of visitors to the site - consumers of this medication, as well as opinions of physicians specialists on the use of Retabolil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Retabolil in the presence of existing structural analogues. Use for the treatment of cachexia and muscular dystrophy in adults, children, as well as during pregnancy and lactation.

Retabolil - synthetic derivative of testosterone, an anabolic drug of prolonged action (depot preparation). Stimulates the synthesis of protein in the body, causes a delay in nitrogen, calcium, sodium, potassium, chlorides and phosphorus, which leads to an increase in muscle mass and accelerated bone growth, water retention in the body. Has low androgenic activity.

Composition

Nandrolone decanoate + excipients.

Pharmacokinetics

Retabolil is slowly released from the injection site into the bloodstream. In the blood, the ether rapidly hydrolyzes into nandrolone. Nandrolone is metabolized in the liver. Metabolites excreted by the kidneys are 19-norandosterone, 19-norethiocholanone and 19-norepiantrosterone. Data on the pharmacological activity of these metabolites are not known.

Indications

Use strictly according to the doctor's prescription to avoid complications.

Diseases in which prolonged use of anabolic agents is necessary:

• osteoporosis of various genesis;
• cachexia of various etiologies;
• violation of protein metabolism after severe burns, injuries, surgical operations, radiation therapy, with severe infectious diseases;
• progressive muscular dystrophy;
• spinal amyotrophy of Werdnig-Hoffmann;
• diabetic retinopathy;
• disseminated breast cancer in women (as a palliative method of treatment);
• glomerulonephritis, program hemodialysis in patients with chronic renal failure.

Retabolil can be used in combination therapy with glucocorticoids, tuberculostatic and cytostatic drugs.

Forms of release

Solution for intramuscular administration oily 50 mg (injections in ampoules for injection).

There are no other dosage forms, be it pills or capsules.

Instructions for use and how to use them

Retabolil can be prescribed for both inpatient and outpatient patients. The drug is administered intramuscularly. The dose of the drug is determined individually. The average single dose for adults is 25-50 mg every 3-4 weeks. With myopathies, individual doses can be set. In severe renal failure, the dose is 50 mg weekly. Oncological patients can be administered at a dose of 50 mg every 5 days.

To children Retabolil is prescribed in a dose of 400 mkg / kg of body weight every 3-4 weeks.

Side effect

• nausea, vomiting;
• loss of appetite;
• burning sensation in the tongue;
• increased or decreased libido;
• acne (especially in women and puberty boys);
• edema;
• cholestasis;
• jaundice;
• increased vascularization of the skin;
• hypercalcemia;
• symptoms of virilization in women (hirsutism, alopecia, irreversible decrease in the tone of voice, irregular menstruation, suppression of ovarian function, an increase in the clitoris);
• suppression of testicles, oligospermia, gynecomastia, penis enlargement, frequent erections at pubertal age in men.

Contraindications

• nephrotic syndrome;
• prostate cancer;
• acute or chronic prostatitis;
• breast cancer in men;
• severe liver damage, liver failure in cancer patients or metastasis in the liver;
• pregnancy and the period of breastfeeding;
• hypersensitivity to any of the components of the drug.

Application in pregnancy and lactation

The drug is contraindicated for use during pregnancy and during breastfeeding.

Application in elderly patients

Data on the use of Retabolil in elderly patients are not provided.

Use in children

In connection with the androgenic activity of children, the drug is prescribed in the event that the anticipated benefit exceeds the potential risk. With the use of Retabolil in high doses at pubertal age, premature closure of the growth zones and the suspension of growth are possible.

special instructions

To achieve the optimal therapeutic effect against Retabolil therapy, the patient should receive adequate amounts of protein, fat, carbohydrates, vitamins, minerals with food.

In connection with androgenic activity of women and children, the drug is prescribed if the intended benefit exceeds the potential risk.

With the use of Retabolil in high doses at pubertal age, premature closure of the growth zones and the suspension of growth are possible.

With caution, the drug should be used for cardiac, renal insufficiency, arterial hypertension, migraine, epilepsy, glaucoma (or in the presence of anamnesis), because anabolic steroids cause a delay in sodium and fluid in the body. During treatment with Retabolil, careful monitoring of intraocular pressure should be performed.

Before and during the treatment with the drug, rectal control of the size of the prostate gland is necessary.

In some cases, against the background of the use of the drug, there are violations of the indices of some functional liver samples. Therefore, every 4 weeks, liver function should be monitored.

In patients with diabetes, Retabolil may cause an increase in glucose tolerance, thereby reducing the need for insulin or oral hypoglycemic agents.

In patients with metastases of breast cancer in the bone, hypercalcemia may develop. In this case, therapy with anabolic steroids can be prescribed only after the normalization of the level of calcium in the blood.

The use of anabolic steroids for the purpose of stimulating athletic qualities (in bodybuilding) can cause serious harm to health and is unacceptable!

The drug is released by prescription.

Drug Interactions

With care, prescribe Retabolil against the backdrop of the use of anticoagulants of indirect action (possibly strengthening their action), hypoglycemic drugs (possibly increasing their hypoglycemic effect).

Analogues of the drug Retabolil

Structural analogs for the active substance:

• Deca of durabolines;
• Phenoboline solution for injection in oil.

Analogues for the pharmacological group (anabolic):

• Inosion;
• Inosine;
• Potassium orotate;
• Magnesium orotate;
• Methandienone;
• Methandrostenolone;
• Methyluracil;
• Proviron;
• Riboxin;
• Ribonosine;
• Silabolin injection for oil;
• Cerebrohororm;
• Ecstysten.

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