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Walsz - instructions for use, reviews, analogs and formulations (tablets 40 mg, 80 mg and 160 mg, with hydrochlorothiazide H form) drug for the treatment of hypertension and pressure reduction in adults, children and pregnancy

Walsz - instructions for use, reviews, analogs and formulations (tablets 40 mg, 80 mg and 160 mg, with hydrochlorothiazide H form) drug for the treatment of hypertension and pressure reduction in adults, children and pregnancy

In this article, you can read the instructions for using the drug Wales. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Valz in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Wales in the presence of existing structural analogues. Use to treat hypertension and reduce blood pressure in adults, children,as well as during pregnancy and lactation.

 

Wales - a peripheral vasodilator, has an antihypertensive effect. The specific blocker of AT1-receptors of angiotensin 2, does not inhibit ACE. Does not affect the content of total XC, TG, glucose and uric acid in the blood.

 

The onset of the effect occurs 2 hours after ingestion, the maximum after 4-6 hours; the duration of the action is more than 24 hours. After regular administration, the maximum decrease in blood pressure occurs in 2-4 weeks. There is no withdrawal syndrome with sudden discontinuation of admission.

 

Composition

 

Valsartan + excipients.

 

Valsartan + hydrochlorothiazide + auxiliary substances (Vals H).

 

Pharmacokinetics

 

After taking the drug inside absorption is fast, the degree of absorption is variable. The average value of absolute bioavailability is 23%. The binding with plasma proteins (mainly with albumins) is high - 94-97%. With repeated use of valsartan, no changes in the kinetic parameters were noted. When taking the drug in a dose 1 time a day, there was an insignificant cumulation of valsartan. Pharmacologically inactive hydroxymetabolite is found in blood plasma in low concentrations.After ingestion, 83% of Valsartan is excreted with bile through the intestine and 13% by the kidneys, mostly unchanged.

 

The concentration of valsartan in the blood plasma does not differ between men and women.

 

When combined with valsartan, the systemic bioavailability of hydrochlorothiazide is reduced by about 30%, hydrochlorothiazide itself does not significantly affect the kinetics of valsartan. The noted interaction does not affect the efficiency of the combined application.

 

Indications

  • arterial hypertension;
  • chronic heart failure (2-4 functional class according to NYHA classification) - as part of complex therapy (excluding combination of valsartan + ACE inhibitor + beta adrenoblocker);
  • with the aim of increasing the survival rate of patients with acute myocardial infarction (period from 12 hours to 10 days) complicated by left ventricular failure and / or left ventricular systolic dysfunction, with stable hemodynamic parameters.

 

Forms of release

 

Tablets coated with 40 mg, 80 mg and 160 mg.

 

Tablets coated with 80 mg + 12.5 mg, 160 mg + 12.5 mg and 160 mg + 25 mg (Vals H).

 

Instructions for use and dosing regimen

 

Assign inside, regardless of food intake, drinking with a sufficient amount of liquid.

 

With arterial hypertension, the recommended initial dose of Vals is 80 mg once a day. The hypotensive effect develops in the first 2 weeks of therapy. The maximum effect is achieved after 4 weeks of taking the drug. In patients for whom a daily dose of 80 mg does not give the desired therapeutic effect, it is recommended to increase the daily dose to 160 mg. Additionally, another antihypertensive agent (e.g., a diuretic) may be administered.

 

For chronic heart failure, the recommended initial dose of Valz is 40 mg twice daily. With insufficient therapeutic effect, a gradual increase in the dose to 80 mg 2 times a day is required and with good tolerability - up to 160 mg 2 times a day. From the moment of the beginning of treatment with Valz until the maximum dose is reached, an interval of at least 2 weeks should be observed. The maximum daily dose is 320 mg in 2 divided doses. It is possible to lower doses while taking diuretics.

 

Valz can be used in combination with other medicines intended for the treatment of chronic heart failure.However, Valz should not be administered in combination with an ACE + beta-blocker inhibitor.

 

After myocardial infarction with stable hemodynamics, treatment can be started within 12 hours after acute myocardial infarction. The initial dose is 20 mg (1/2 tablet 40 mg) 2 times a day, followed by a dose increase of 40 mg, 80 mg, 160 mg twice a day for several weeks, until the maximum daily dose of 160 mg 2 times in day. Reaching a dose of 80 mg twice a day is recommended by the end of the second week of treatment, 160 mg twice a day - by the end of 3 months of therapy. The dose should be increased taking into account the tolerability of the drug. In the case of symptomatic arterial hypotension or with impaired renal function, the dose of Valz should be reduced.

 

In patients with mild and moderate impairment of liver function without development of cholestasis, the maximum daily dose of Valz should not exceed 80 mg.

 

WALZ H

 

The drug is taken orally, regardless of the time of ingestion, with a sufficient amount of liquid.

 

The following doses of Valz H are indicated in the ratio of valsartan / hydrochlorothiazide.

 

The recommended dose is 1 tablet of 80 / 12.5 mg once a day.If the drug is ineffective at this dose, it is recommended to increase the daily dose of Vals H to 160 / 12.5 mg, for those patients who show a further decrease in blood pressure, the daily dose of Valz H is 160/25 mg, respectively.

 

Patients with renal dysfunction with CK> 30 ml / min, as well as patients with mild or moderate liver function impairment in the absence of the phenomena of cholestasis do not need a dose adjustment of the drug Valz N.

 

Side effect

  • orthostatic hypotension;
  • a decrease in blood pressure;
  • heart failure;
  • vasculitis;
  • bleeding;
  • cough;
  • diarrhea;
  • abdominal pain;
  • nausea;
  • postural dizziness;
  • fainting;
  • insomnia;
  • depression;
  • decreased libido;
  • neuralgia;
  • headache;
  • neutropenia, thrombocytopenia;
  • serum sickness;
  • hypersensitivity;
  • angioedema;
  • skin rash;
  • itching;
  • backache;
  • muscle cramps;
  • arthritis;
  • myalgia;
  • arthralgia;
  • impaired renal function;
  • acute renal insufficiency;
  • viral infections;
  • sinusitis;
  • conjunctivitis;
  • rhinitis;
  • gastroenteritis;
  • reduction of hemoglobin and hematocrit;
  • increase in the concentration of urea nitrogen in the serum;
  • feeling tired;
  • asthenia;
  • nose bleed;
  • edema.

 

Contraindications

  • violations of the liver, associated with obstruction of the biliary tract (including biliary cirrhosis, cholestasis);
  • renal failure of severe degree (QC less than 10 ml / min), incl. patients on hemodialysis;
  • pregnancy;
  • lactation period (breastfeeding);
  • age under 18 years (effectiveness and safety not established);
  • lactose intolerance, galactosemia or syndrome of impaired glucose / galactose absorption;
  • hypersensitivity to the components of the drug.

 

Application in pregnancy and lactation

 

There are no data on the use of valsartan in pregnancy. Renal perfusion of the fetus, which depends on the development of the renin-angiotensin system (RAAS), begins to function in the third trimester of pregnancy. The risk to the fetus increases with the use of valsartan in the 2nd and 3rd trimesters. When establishing a pregnancy, therapy with Vals should be stopped immediately.

 

There is no data on the isolation of valsartan with breast milk. Therefore, if you need to use the drug inlactation period should decide whether to stop breastfeeding or to abolish valsartan therapy given its importance to the mother.

 

Use in children

 

Contraindicated in children and adolescents under the age of 18 years (efficacy and safety not established).

 

special instructions

 

In patients with severe sodium deficiency in the body and / or reduced bcc, for example, due to the use of diuretics in high doses, in rare cases, severe arterial hypotension may develop at the onset of valsartan therapy. Before starting therapy with Vals, it is recommended to restore the electrolyte and fluid content in the body, in particular, by reducing the dose of diuretics.

 

The drug Valz can be used in conjunction with other drugs intended for the treatment of myocardial infarction, such as thrombolytics, acetylsalicylic acid, beta-adrenoblockers, statins and diuretics. Joint administration of ACE inhibitors is not recommended.

 

With renovascular hypertension, regular monitoring of urea and creatinine in the blood is necessary.

 

When combined with preparations containing potassium, its salts and preparations belonging to the group of potassium-sparing diuretics, regular monitoring of the level of potassium in the blood plasma is carried out.

 

In chronic heart failure at the beginning of treatment with the drug Valz, there may be a slight decrease in blood pressure, so it is recommended to monitor BP at the beginning of therapy.

 

Due to inhibition of RAAS, some patients may have renal function changes. In patients with severe chronic heart failure, whose renal function depends on RAAS activity, treatment with ACE inhibitors and angiotensin receptor antagonists may be accompanied by oliguria and / or increased azotemia and (rarely) acute renal failure and / or fatal.

 

It is not recommended joint use of Valz in patients with chronic heart failure, with ACE inhibitors and beta-blockers due to a possible increase in the risk of side effects.

 

Patients with bilateral or unilateral stenosis of the renal arteries need regular monitoring of creatinine and urea Nitrogen in the blood serum.

 

Impact on the ability to drive vehicles and manage mechanisms

 

During the treatment period, care must be taken when driving vehicles and classesother potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions.

 

Drug Interactions

 

When treating arterial hypertension with valsartan, there was no clinically significant interaction with other concomitant medications (for example, cimetidine, warfarin, digoxin, atenolol, amlodipine, glibenclamide, furosemide, indomethacin, hydrochlorothiazide).

 

Potassium-sparing diuretics, potassium preparations, potassium-containing salts, drugs that raise the level of potassium in the blood plasma (such as heparin) increase the risk of hyperkalemia.

 

Other antihypertensives and diuretics increase the antihypertensive effect of valsartan.

 

Ethanol (alcohol) enhances the hypotensive effect of the drug Valz.

 

The antihypertensive effect of the drug may be weakened when combined with non-steroidal anti-inflammatory drugs (NSAIDs), incl. with selective inhibitors of COX-2 and Acetylsalicylic acid at a dose of more than 3 g per day.

 

In a joint application with ACE inhibitors, a reversible increase in the concentration of lithium in plasma and the development of toxic effects were reported.

 

Very limited experience in the use of valsartan and preparations containing lithium.In the case of lithium-containing drugs, control of lithium concentration in blood plasma is recommended in patients receiving Valz.

 

Analogues of Val's drug

 

Structural analogs for the active substance:

  • Valsartan;
  • Valsafors;
  • Walsakor;
  • Diovan;
  • Nortivan;
  • Tantordio;
  • Tareg.

Similar medicines:

Other medicines:

Reviews (88):
Guests
Liana
I accept the second day. There is dizziness.
Guests
Olga
There was pressure up to 150, jumps. They assigned the Wales 80 for three months - the pressure became like a watch 120/80. Now I do not drink and again pressure. I think again it or him to accept, but here I do not know constantly it is possible to drink it or not, and so the response only positive.
Administrators
admin
OlgaAll medicines for pressure are taken on an ongoing basis. So return to the scheme that gave you a positive result and take the medication constantly. You can only adjust the dosage of the drug, which has a positive effect, but can not be taken snatches.
Guests
Tatyana
Pressure and jumped from 120 to 160.After 2 weeks of intake - a cough, continued to drink, reached the cough attacks of the strongest, to the veins of blood ... Now also problems with the eyes. I'm sorting it out ... I stopped taking the cough and started coughing. I did not fit.
Guests
Nadezhda
Headache, back pain, fatigue.
Administrators
admin
NadezhdaAre you the side effects of the drug Wals have you described? And then the recall is not clear ...
Guests
Nina
I accept two years, the result is good.
Guests
Sergei
After a heart attack, Valsakor took more than a year - the pressure was almost always normal at 120x80. Sometimes dizziness, but maybe it's not because of the drug, it's hard to determine.
Now in the pharmacy in connection with the lack of Valsakor offered Wales. Just started to take - I hope that the effect will be no worse than from Valsakor.
Guests
Elena G.
Accepted Valz N 160 / 12.5 for two months. The pressure immediately normalized, often was even low.But the side effects: severe headache, back aches, especially at night, fatigue. Vertigo was also, but perhaps it's another disease. The doctor lowered the dose to 80 / 12.5. There was a headache and pains in the back.
Guests
Antonina (Nina)
It seems that all reviews on the drugs on this site are custom-made! I wrote several times a review on Valsa 160 + 25 mg, I wanted to warn people about pobochke and all my attempts are futile. Alas, it's a great pity! But people believe!
Administrators
admin
Antonina (Nina), All correct responses are published on the site as is, without corrections. And with custom-made, I personally fight to the best of my abilities.

The exception concerns only the reviews in which there is the praise of other drugs, then the recall can be removed, especially if it is clear that this is an ordinary customized opinion with the goal of smearing one drug (analog) and raising the estimate of another in the eyes of consumers, the methodology has already been worked out.

A response can also be rejected, which contains a question and is asked on behalf of an unregistered visitor.The load due to the winter-spring surge in the incidence increased and it was decided to provide a full consultation to registered visitors. You, as I look, are not registered on the site, so if your feedback contained a question it could well be rejected.

Also, do not forget about the glitches at the time of sending messages, if you did not see the window about the positive acceptance of your recall for moderation, then did not fill in any mandatory field and the feedback simply was not added.

I suggest you leave your review again and you will soon see it on the site.
Guests
Galina
I take the drug Valz N from April 2014 regularly. Was appointed after a hypertensive crisis (the pressure was 230 \ 120). My pressure jumps stopped, I noticed no side effects.
Guests
galena
She took a month. There was no effect whatsoever, there was pressure. I had to switch to Lopaz Plus. Not everyone approaches it.
Guests
oxane A.
At reception of this preparation at my mum the strong dry tussis, a rhinitis has developed.
Guests
doctor katya 1
I accept valz 160 mg + arifon retard more than a month. The blood pressure is not reduced.
Guests
Vladimir E.
Hello. I struggle with blood pressure for more than 30 years. What did not I drink. About a year ago stopped drinking amprilan, which, in general, helped. Abolished admission pulmonologist: all "by-catch" bronchiospasm - one of the side effects. Now on the sick-list: 150/105 two weeks. Pew Wals N. Helps (me) less than "prilah", unfortunately. The maximum was reduced to 140/90. And in general, you need to talk less about your illnesses, and adjust to the positive and always believe that you will be healthy, no matter what, and live for 100 years. I wish all people health and happiness!
Vladimir, 55 years old.
Patient 75 years old, hypertension 2 stages. VALZ in constant admission, currently for 2 weeks at a dosage of 80 mg in the morning intake, with the possible addition of a dose of up to 160 mg. So far, pah-pah, supports blood pressure within the limits of the targets (140x90, often 120x80), sometimes a little higher (for example, 150x80).During the reception there was only one unplanned pressure rise (overcast, rain with thunder, storm warning). With blood pressure a little more than usual, we add 1/2 of the VALZ tablet in the morning reception, with normal or close to normal BP allowed to take in the morning also half a tablet with mandatory control in the next hour or two. In an emergency admission during the day in the scheme if necessary, a hood (a tablet of 25 mg), or also allowed cordaflex.
Guests
Olga
It lowers blood pressure well, but has a severe cough. It is a pity that you have to cancel.
Hello! Tell me, please, if possible, can this be a side effect of VALZ on the skin and if so, what can I do?

There were pains in the right side of the chest (more precisely under the breast, in a woman). After a while at this place a few red spots appeared with pimples in the center, then they merged together. With increasing pains, the "pimples" began to turn into blisters, and the redness around them faded.The pain is not all the time, by the evening it intensified, at the moments of the most severe pain "as if stuck in a pinch" (flat, in places of redness), I even had to drink painkillers to calmly spend the night. Before the formation of blisters rose subfebrile temperature (37.2-37.5), the head was very sick.
Administrators
admin
Natalia 08042015Most likely with the use of the drug Valz, this symptomatology is not related. According to the description, it is more like herpes or its variant - shingles, and apparently the patient is aged, because the reaction to infection is strong, and this can only be in a weakened organism. I advise you to see a full-time doctor for examination and treatment.
Guests
olga 77
I accept the Wales in the morning, from 2011. Everything is fine. The doctor does not cancel ...
Guests
Olga
After two months of using WALZ 80, sleep was disturbed. I fall asleep only with pills or after five in the morning. I think it's related to Wales.
Hello! If possible, please explain what does it mean to mention "viral infections" as side effects from taking VALZ? Does this mean that taking this medication can weaken the immune system? The question is not from idle curiosity. Thank you very much in advance. With the same respect.
Administrators
admin
Natalia 08042015, This means that with the use of the drug Vals may more frequent development of secondary viral infections than without the use of this drug. About immunity I will not say, perhaps this side effect has another development mechanism, for example, the effect on the cell wall and the adhesion of viruses, but this can only be guessed.
Please tell me, can valsartan cause vasoconstriction or spasms? We are all trying to find the cause of the noise in the ears of my mother; noise is bothering, despite more than six months of treatment.
Administrators
admin
Natalia 08042015, Again, add to the previously said to other your questions (to other drugs).Perhaps everything, including the medicinal effect, if the noise appeared at the time of the beginning of the drug Valz. If such a link is not proven (for example, they started taking the medicine and the noise appeared in a month), then it is necessary to look for other possible causes. You can cancel the drug, but since Wals is a first-line drug, it can only be replaced, it can not be canceled, because a pressure jump can occur that will cause critical changes in the patient's health.
Guests
Lyudmila
I drink about six months. Month picked up a dose. The pressure was normal. I take Valz 80 mg / 2 times a day + 5 mg Norvasc. Now I have a blood test. Hemoglobin fell from 130 to 105. Iron from 14 to 4.8. Hematocrit and ferritin also became lower, but so far in the normal range. There was weakness, pain in the muscles. Insomnia. To all in addition, even pressure was often low - 105/55. Pulse 95. Tomorrow I go to the doctor to find out the reason and take action.
Guests
Lyudmila K.
I have terrible constipation began abruptly. Two weeks already. No laxatives help. Associate this with the beginning of the application of WALZE. In the morning to 160 mg.
Hello. I have diabetes 2 groups and hypertension. Since morning I accept indapamid 2.5, and in the evening Amlodipin and valsakor or valz. Also three times a day I take Glucophage 850. How long can I use Valsakor? May need to take breaks?
Administrators
admin
MIGDALOV VADIM, Cardiac drugs or drugs to reduce blood pressure, such as those you mentioned Valz or Valsakor are taken for a long time, often for life. Their cancellation is possible only with the permission of the attending physician and occurs usually in young patients with short-term pressure surges caused by psychological causes or stress. Interruptions in taking these medications are also unacceptable.
Thanks for the answer. One more question, I know that indapamide purifies potassium, and amlodipine blocks potassium channels. Prompt please do not take any drug to maintain potassium in the body?
Administrators
admin
MIGDALOV VADIM, You can short-term courses and more pills at a time to take Asparks or Panangin, if you have been taking indapamide for a long time. Amlodipine had no negative effect on potassium metabolism, including from medical experience.
Hello, tell me whether you still need to take valz along with indapamide and amlodipine. In general, what he gives, I just have many side effects from him. Thankful in advance for the answer.
Administrators
admin
MIGDALOV VADIMWhether or not your PCP is necessary or not, a cardiologist who knows your medical history and tests / studies is better. Online you can cure yourself of a cold, but it's hardly possible to prescribe drugs for pressure. A gives Waltz an antihypertensive effect, that is, it lowers high blood pressure. If there are side effects - this is also an occasion to consult a doctor to adjust the dose of medications taken, or replace drugs with others that are more suitable for you.
Guests
Tatyana
Wales keeps the pressure, but I have coughing and cramping from him.
Guests
Love
With the reception of Wales, heartburn is observed. She ceased taking - heartburn stopped. And pressure keeps well in norm.
Guests
Love
I accept Valz H 80 only 5 days. The pressure returned to normal, but when swallowing food and water, the pain in the esophagus area (and the first 2 days of pain in this area even at night was), as if bad passing. And heartburn is strong, belching gastric juice. Very frightening. It can not be abolished abruptly. It is necessary to go to the doctor.
Guests
Sverchkova Nina
And Wales does not help me at all. But the drug helps Diofor (valsartan + amlodipine). I was assigned to him in Tunisia.
Guests
Lyudmila
I am 73 years old. I accept the Wales from 2013. At first she took Valz 160 + Arifon 1 time in the morning. At first everything was wonderful. Then the pressure in the evening increased. Began to take the scheme: in the morning, Wals-80 + arifon retard, in the evening WALZ-80 + aspirin cardio. There are pressure jumps, but when the weather is bad or a scary movie is on TV.
Administrators
admin
Site visitor question aliona1989 moved to the required section:
Good afternoon. To my mother of 57 years, she constantly suffered high pressure. 2 days ago her pressure rose to 220/180. Were at the cardiologist he to us has appointed or nominated to accept Valz h on 0,5 tablets in the morning and in the evening and bidop on 0,5 tablets 2 times a day. This morning, my mother woke up to her, the pressure dropped 110/90. Is it not scary or can reduce the dose?
aliona1989Of course, with a sharp drop in pressure, the dosage of the drugs needs to be adjusted, but you and as I understood the low dosages, although the dosage of half a tablet does not give me anything, it is necessary to indicate how much the tablet contains the active substance in order to understand what can be reduced. On quarters, pills are usually not divide and remove from the scheme some of the drugs according to the situation. Although in the case of your mother, I would wait three days and see what will happen with the pressure, since 110 by 90 mm Hg. not particularly critical numbers, you can wait. And until the end I can not understand whether I corrected the name of the drug Valz H, which you indicated in the question. The situation requires clarification.
Visitors
fynjyjdf
At what AP in general appoint or nominate Valz? My pressure above 140/90 rises very rarely (... 146/92). There is a low blood pressure, I suffer badly - my head is spinning. I was sick with acute bronchitis, a strong cough, the pressure began to rise to 152/100. It lasted a week. Have appointed or nominated Valz: constant lowered pressure, a giddiness, sensation of "zazhatosti" in a head, noise in ears. Of the prescribed 160 drink 40 in the morning, the pressure drops, I walk in this state. (In case of a "bradycardia" BIDOP is also appointed ...)
Administrators
admin
fynjyjdfRegarding Valz, of course, with such pressure figures, and if no other drugs were used to reduce the pressure, I would start with minimal doses of the drug, but rather choose something simple and cheap, but in your case no less effective - for example, inhibitors ACE (Enalapril, lisinopril and other drugs) in minimal dosages. In addition, doctors should know that during and for some period after severe infectious diseases, the pressure may rise, and after recovery, it may decrease. In this case, you can designate the minimum dosage of drugs that lower high blood pressure,and then gradually cancel them and see the effect, you may have to return the use of antihypertensive drugs, but at least not in such dosages. The lower the pressure you carry badly.

Bidop is probably prescribed for tachycardia (when the pulse is rapid), if not, then something is wrong for you or for another reason.
Guests
zenchenko hope mihaylovna Kazakhstan
Good afternoon. I am grateful to the cardiologist from Krasnodar who correctly picked up the medicine Valz 160 and carvedilol. Pressure is normal, I take 4 years. I'm 69 years old, lying constantly in hospitals, the pressure went off and could not determine what, the diagnosis was of unknown origin. It's just a pity that we do not have this medicine in Kazakhstan, and the substitute does not suit me. So you have to go to Russia and buy it right away for a whole year. All of health and believe in yourself.
Guests
Lyudmila
At me a ciliary arrhythmia, an ischemic heart disease, heart failure. I take Amiodarone in the morning of 100 mg for 6 years already. Now the pressure began to increase and mostly in the evening to 169 by 90. Wales was discharged. Tell or say it is possible to accept it or him at such diseases?
Administrators
admin
Lyudmila, Yes Valz well reduces high blood pressure, if it suits a particular patient. At arrhythmias and with Amiodarone its reception is possible, there should not be any negative in this case.
Guests
Zoe Slabey (Gracheva) Kemerovo.
Month spent on drinking Wales N 160, a good result was. Swelling of the joints began. Apparently it does not go to those who have arthrosis and arthritis. The bad news is that doctors do not ask about these diseases. The person begins to read, look for pobochki, analyze. Thanks to the internet.
Guests
Lydia 65 years old
I take Wals 80 for 3 years in the morning one tablet, but the doctor told me that it is necessary to drink constantly, and in the evening amlodipine one tablet. I felt much better, the pressure was normal.
Visitors
valia.gamova
Hello! I've been taking Wales for 2 years and Concor. I got a shortness of breath, I tell doctors, they deny it.
Administrators
admin
valia.gamovaBoth of the drugs mentioned in the question can cause obstruction, with Concor more than Wales. I think you can check for a while by canceling both drugs or in turn starting with Concor, if the pressure-heart diagnosis is not life threatening.
Guests
Irina
The husband drinks Vals for 3 years with Egilokom, but the cough is very strong.
Guests
alexander 64 g
Accepted lisinopril, well holds the pressure in norm, but cough and headache ... The cardiologist has appointed or nominated valz, I read responses about and the same pobochki, but I will try to have a drink.
Hello, dear admin! Tell me please. Mom stops helping Wales. Took it daily for almost two years, stably maintained pressure (dosage of 80), caused a minimum of side effects. In recent times, cases of increased pressure for some reason in the evening and night, the increase in dosage to 160 does not help. Cordaflex, which was allowed to her as a drug for emergency action, for some reason, too, is slower than usual, as if he and Valsa are hindered.
What could be the reason for such a decrease in the effectiveness of the Valls? Is it permissible for him to be replaced by another sartan? (The question is not for self-treatment).
Thank you very much in advance.
Administrators
admin
Natalia 08042015, With prolonged use of antihypertensive drugs, some patients may experience habituation and decreased effectiveness of the action. You can try to replace both the other-sartan, and the drugs of any other group of antihypertensive drugs. It is likely that such an outcome is that after some time using the drug from another pharmacological group, the drug Valz will return effectiveness in stopping excess pressure from your mother. Also, given the nature of the increase in the evening or at night, you can try to use at night or in the afternoon Amlodipine or Moxonidine and their commercial counterparts, if these drugs for additional parameters are not contraindicated to the patient.
The pressure is 180-200 / 120. Two days ago, a therapy was prescribed, but the pressure did not go down, although in general the condition improved,of course. Assigned: in the morning Wals 80, Concor 2.5 and in the evening Norvasc 5. When to wait for improvement in the pressure indicators and is it worth it?
Administrators
admin
Marina Yuryevna, Stabilize the condition in which you can judge the effect of therapy should be within 2 weeks (after this significant pressure surges should not be, if there is, then it is necessary to change the treatment), but the pressure should decrease within 1 week. Wait for this period and if the pressure remains the same high, it is worth asking the doctor for adjusting the therapy.
Apparently, in our case there is a connection between the moments of Vals efficiency decrease and the days of magnetic storms. Previously, it was not like this.
Guests
Nina Alekseevna
I have been drinking Wals for 7 years already, the pressure is holding up normally. I wanted to go to other drugs, on the advice of a doctor, does not help, I'll try and back to the valz. They began to bother the joints. I think it's a side effect on the waltz.
Guests
Rausinya
After taking Valz, my tinnitus becomes worse.
Guests
Anatoly 1
I do not know about these pills anything. And I want to say that the administrator is a fine fellow. It responds to questions, does not launch topics. Follows everything here for more than one year, apparently. Excellent work and necessary for people.
Guests
Tatyana Pavlovna
I drink 2 years of Wales H 80. Rose sugar. The pressure dropped. The pulse became more frequent.
Administrators
admin
Anatoly 1, Thank you. I try to measure my strength and capabilities.
Visitors
vikont150255
Peel Wales 160 six months, the pressure was stable. Three days I do not drink, the pressure jumped 180/120. Can I continue drinking it again?
Administrators
admin
vikont150255, Drugs from pressure are taken for a long time, and if the patient is aged mostly for life or until they are canceled by the attending physician. So the decision to return to taking Valz 160 is right and you should not cancel it yourself.
Hello, dear admin! Tell me please.
Is it true that the use of the drug VALZ "suppresses the renin-angiotensin-aldosterone system"? If it is true, and still have to leave with VALZ because of a decrease in its effectiveness, what kind of drug can be substituted so that there is no "oppression of the RAAS"?
Thank you very much in advance.
Administrators
admin
Natalia 08042015, In patients with combined chronic heart failure (CHF) and it is necessary to eliminate the negative consequences of hyperactivity of RAAS. So I do not see any prejudice here. The drugs have a list of contraindications and side effects, if a patient exhibits something negative, then it makes sense to play with other drugs (the same ACE inhibitors, aliskiren-based drugs will also have similar effects on RAAS).
Guests
Tatyana
On the appointment of a doctor, I take Valse 80 for 80 years, Bisoprolol was prescribed a year ago. I have been suffering from a cough for several months, and I have been treated for bronchitis.A wet cough has passed, but I have a dry cough all the time. There were problems with the voice. Phonyator believes that the cause of bisoprolol, and the therapist says that bisoprolol does not affect the voice.
Guests
Irina
At mum from reception VALZ a cough. What to do? I changed the drug, but the pressure began to hold.
Guests
Elena 330182
The father of 70 years, has started to accept (within 3 months) VALZ - 80 mg / sut. Pressure keeps well, less often there are attacks of atrial fibrillation (on Enalapril and Prestarium-A they arose more often). But ... recently there were swelling on the back of the feet and legs ...
Guests
Alla
At VALZe "I sit" a year already. Tortured vertigo, not decreasing after taking the drug. Apparently, all individually - one is suitable, the other - no.
Visitors
46tigric
My mom has been drinking it for a month, while there are no changes, the pressure jumps, we do not know whether to continue drinking it further. Can I take both croaksan and wale?
Guests
Alla
I have problems associated with increased dizziness after taking the drug at a dose of 80 / 12.5. Cough is also present.
Administrators
admin
46tigric, Joint use of Valz and Coraxan preparations in one therapy scheme is possible. According to the instructions and from the experience of additional negative side effects, when combined using the medicines mentioned in the question should not be.

Irina, Change to antihypertensive drugs of other groups, select other therapy regimens. It is impossible to get rid of a cough when taking Valz, because this phenomenon has an allergic nature and the use of antitussives and such a special effect will not. A similar side effect can occur in patients taking this medication.
Guests
luminous n
I take Vals 80 and Amlodipine for over a year. The pressure returned to normal, but at night the seizures and numbness of the legs and hands began to be excruciated. Actually, I have a lumbar osteochondrosis for a long time, maybe this is not related to Wales.
Guests
Galina
Pugh valz 140 in the morning + arifon and in the evening 180 + lercamen 10. Pressure rises to 170. Probably, it does not.
Guests
Надежда 78 years
I accept valz on 40 mg in the evening more than 3 years. The last six months in the morning, blood pressure is low to 100/60. I feel bad at the same time - weakness, acute bronchiectasis, all teeth ache.
Visitors
pvs
Good afternoon. Valz taken at a dose in the morning of 80 + 1.5 + 0.5 indapamide bisoprolol, the evening of 80 + 0.5 + 5 bisoprolol, amlodipine, throughout the year after suffering a heart attack, it was all well kept pressure 120/80, and the attacks were rescued moxonidine and hood . A month ago the pressure began to hold 135-140 / 80-85, the attending physician added a dose of WALS to 120, does not help. Now the second day I take 160 in the morning and in the evening, the pressure is 140/80. Tell me please, is it an addictive effect?
Administrators
admin
pvs, Yes, it seems like the addiction of the body and its immunity to the drug taken. Most likely, we should try to push off the drug Valz in the direction of another antihypertensive drug based on another active substance.Address to the attending physician, it is better if it will be the cardiologist, for selection of an adequate replacement, respectively, of your profile of concomitant diseases and previous treatment.
Guests
Lyudmila K.
I take the drug for more than a year. Pressure jumps, but more than 160 did not rise. Would continue to drink, but a lot of side effects. Increased creatine and urea in the blood, above normal. All large and small joints became painful, I had arthrosis of large joints, and now all small ones. Now I treat kidneys and joints, and I'm afraid to take wals.
Guests
Tatyana
Who all the same should prescribe preparations from pressure, the therapist or the cardiologist?
Administrators
admin
Tatyana, Cardiologist - a specialist in a narrow profile on the problems of the cardiovascular system, the therapist is a general practitioner. To solve problems in the initial stages of the disease it is quite enough consultation and appointments of the therapist, it is worthwhile to apply to a cardiologist if the therapy prescribed by the therapist is ineffective or if serious cardiac health disorders occur.A therapist may be referred to a narrow specialist in the patient.
Guests
Irina
I have bronchial asthma and ischemic stroke with hypertension, and I was prescribed in the hospital to drink enalapril 20 mg, verapamil 180 mg, and so I want to note that, from enalapril, I have a wild dry cough and asthma attacks. I was replaced by lorist 100 mg and verapamil 180 mg, I drank 4 long years and I want to note that enalapril helped me better and much, but I had to drink the lorist because of asthma. In short, I disfigured myself with this losist and clopidogrel for the dilution of blood 75 mg, from lobsters and clopidogrel from swallowing my legs swelled, in the evenings chills, a cough of dry swallowing into an attack, my whole body ached, could not get up in the morning. And no doctor even suggested. I went to a paid clinic, and the cardiologist canceled everything for me and appointed a 180 mg amp and 180 mg diltiazem, and I immediately stopped coughing, stopped gasping and the swelling was asleep on the 2nd day of reception, my back does not hurt. That's how I cured myself. I've been drinking for a week and I feel great.
Guests
Galina
I accept 80 for almost three years, I divide the tablet into two parts and take half the morning and evening, plus a quarter of aspirin. The pressure is normal ...
Guests
Nikolay Nikolaevich
I've been drinking 160 H for six months already and do not feel any results. Maybe it's because there are a lot of fakes on the drugs market ...
Visitors
apacer1983
I am 33 years old. At me a hypertonic illness or disease of 1 stage, a sinus tachycardia, kfk 219, ast 20, alt 15, lpvp 1.0, lpnp 3.4, cholesterol 4.7. I was prescribed Valz 40 mg in the morning and Panangin 3 times a day and 5 mg at night. You can drink Wales and Panangin together?
Administrators
admin
apacer1983Given the tachycardia, I would better assign beta-blockers to reduce the pulse rate, along with the drugs of this group have an antihypertensive effect (Bisoprolol, Nebilet, Concor and others), but if there are no contraindications. The meaning of the appointment of Terialdzhen in the matter is also not disclosed, so on the conscience of your doctor.

Wals and Panangin are a bad combination, given that Wals can provoke hyperkalemia alone. Especially in the analysis of blood you did not make potassium and understand whether you really have a deficiency of this element is impossible.

And more KFK is a little bit raised, or there was a physical loading before delivery of the analysis,or it is necessary to understand what damage to the muscle tissue and where it happened. Perhaps it is worth doing an ECG.

For a combination of factors, I would apply for correction of treatment or approval of appointments to another specialist for monitoring.
Guests
Tamara Mihailovna
I tried to drink Wales, but he does not suit me. My relative has been drinking it for the third year already and feels well. Of course, the cardiologist will choose the right treatment.
Guests
Galina
I accept Valz for 6 months, the pressure is normal. At first I took 80 mg, now I divide 160 mg for 4 days, sleep is also a little broken, but I try to drink tea with herbs before bed, sometimes a quarter of a pill of sleeping pills. In general, I sighed when I began to take Wales.
Guests
A GUEST
WALZ is a very bad medicine. There are a lot of side symptoms, but you only understand it when you buy it. Even pharmacists in pharmacies say that they have bought less of this medicine. How many people paid for the waltz and threw it out, and how many people else our doctors will divorce for money. So do not completely trust doctors. I wish everyone to find their clever specialist.Be careful and study your illness.

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