Wobenzym - instructions for use, reviews, analogs and forms of release (tablets) drugs for the treatment of cystitis, thrombophlebitis and sexually transmitted infections in adults, children and pregnancy
In this article, you can read the instructions for using the drug Wobenzym. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Wobenzima in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Wobenzym analogues in the presence of existing structural analogues. Use for the treatment of cystitis, thrombophlebitis, sinusitis, sexually transmitted infections in adults, children, as well as during pregnancy and lactation.
Wobenzym combined preparation.It is a combination of highly active enzymes of vegetable and animal origin. Has immunomodulatory, anti-inflammatory, fibrinolytic, decongestant, antiplatelet and secondary analgesic effect.
Wobenzym has a positive effect on the course of the inflammatory process, limits the pathological manifestations of autoimmune and immunocomplex processes, positively influences the immunological reactivity of the organism. Stimulates and regulates the functional activity of monocyte-macrophages, natural killers, stimulates antitumor immunity, cytotoxic T-lymphocytes, phagocytic activity of cells.
Under the influence of Wobenzim, the number of circulating immune complexes decreases and the membrane deposits of immune complexes are removed from the tissues.
Wobenzym reduces infiltration of interstitium by plasma cells. Increases the elimination of protein detritus and fibrin deposits in the inflammation zone, accelerates the lysis of toxic metabolic products and dying tissues, improves resorption of hematomas and edema, normalizes the permeability of the vessel walls.
Wobenzym reduces the concentration of thromboxane and platelet aggregation.It regulates adhesion of blood cells increases the capacity of erythrocytes to change its shape by adjusting their ductility, and normalizes the number of normal discocytes (platelet) and reduces the total number of activated forms of platelets, and normalizes blood viscosity, reduces the total number mikroagregantov, thereby improving microcirculation and blood rheology, and also supplying tissues with oxygen and nutrients.
Vobenzim normalizes lipid metabolism, reduces the endogenous synthesis of cholesterol, increases HDL, reduces the level of atherogenic lipids, improves absorption of polyunsaturated fatty acids.
Vobenzim increases the effectiveness of antibiotic therapy, increasing the concentration of antibiotic in blood and plasma, the inflammation and reduces the side effects of antibiotics (dysbiosis).
Wobenzym reduces the severity of side effects associated with taking hormonal drugs (including hypercoagulable).
Wobenzym regulates the mechanisms of nonspecific defense (the production of interferons), thereby demonstrating antiviral and antimicrobial effects.
Pharmacokinetics
After taking Wobenzim, the enzymes included in the preparation are absorbed from the small intestine by resorption of intact molecules and, when bound to blood transport proteins, enter the bloodstream. Then, the enzymes, migrating along the vascular bed, accumulate in the zone of the pathological process.
Indications
As part of complex therapy:
- thrombophlebitis (including acute thrombophlebitis of superficial veins), post-phlebitis syndrome, obliterating endarteritis and atherosclerosis of lower limb arteries, lymphatic edema, prevention of recurrent phlebitis;
- cystitis, cystopyelitis, prostatitis;
- sexually transmitted infections;
- chronic infections of the genitals, gestosis, mastopathy, adnexitis, to reduce the frequency and severity of side effects of hormone replacement therapy in gynecology;
- angina pectoris, subacute stage of myocardial infarction (to improve the rheological properties of the blood);
- sinusitis, bronchitis, pneumonia;
- pancreatitis, hepatitis;
- pyelonephritis, glomerulonephritis;
- Diabetic angiopathy, diabetic retinopathy;
- autoimmune thyroiditis;
- Rheumatoid arthritis, reactive arthritis, Bechterew's disease;
- atopic dermatitis, acne;
- multiple sclerosis;
- uveitis, iridocyclitis, hemophthalmus, application in ophthalmic surgery;
- treatment of postoperative complications (inflammatory processes, thrombosis, edema), adhesions, posttraumatic and lymphatic edema, plastic and reconstructive operations;
- traumas, fractures, distortions, ligamentous apparatus injuries, bruises, chronic posttraumatic processes, inflammations of soft tissues, burns, injuries in sports medicine.
Prevention:
- disorders of microcirculation, post-stress disorders, as well as disruption of adaptation mechanisms;
- side effects of hormone replacement therapy, hormonal contraception;
- with surgical interventions to prevent infectious complications and adhesions.
- It is recommended to prevent infectious complications and improve the quality of life during chemo- or radiotherapy; viral infections and their complications.
Forms of release
Tablets, coated with a shell, soluble in the intestine, in blisters or a bottle of 20, 40 or 800 tablets.
Instructions for use and dosing regimen
Established individually, depending on the severity of the disease.
Adults, depending on the activity and severity of the disease prescribed in a dose of 3 to 10 tablets 3 times a day.In the first 3 days of taking the drug, the recommended dose is 3 tablets 3 times a day.
With an average disease activity, the drug is prescribed in a dose of 5-7 tablets 3 times a day for 2 weeks. In the future, the dose should be reduced to 3-5 tablets 3 times a day. Course - 2 weeks.
With a high disease activity, the drug is prescribed in a dose of 7-10 tablets 3 times a day for 2-3 weeks. In the future, the dose should be reduced to 5 tablets 3 times a day. Course - 2-3 months.
With chronic long-term diseases, Wobenzym can be used according to the indications of courses from 3 to 6 months or more.
To increase the effectiveness of antibiotics and prevent dysbacteriosis, Wobenzym should be used throughout the course of antibiotic therapy at a dose of 5 tablets 3 times a day. After stopping the course of antibiotic therapy to restore the microflora of the intestine Wobenzym should be prescribed 3 tablets 3 times a day for 2 weeks.
During the radiotherapy and chemotherapy, Wobenzym should be used in a dose of 5 tablets 3 times a day before the end of the course of radiation and chemotherapy to prevent infectious complications, improve the tolerability of basic therapy and improve the quality of life.
With the preventive purpose of Wobenzim 3 tablets are prescribed 3 times a day for 1.5 months with a repetition of the course 2-3 times a year.
Children aged 5-12 years are prescribed in a daily dose of 1 tablet per 6 kg of body weight. Children older than 12 years of age, the drug is prescribed according to a scheme designed for adults. The duration of treatment is determined individually.
The drug should be taken at least 30 minutes before eating, without chewing, washing with water (200 ml).
Side effect
Wobenzym, as a rule, is well tolerated by patients. In most cases of side effects, withdrawal syndrome, addiction was not observed even with prolonged use in high doses.
In some cases: slight changes in the consistency and odor of stool, urticaria (go with a lower dose or drug withdrawal).
The patient should be warned that if other side effects occur, it is recommended that you stop taking the drug and consult a doctor.
Contraindications
- diseases associated with an increased likelihood of bleeding (including hemophilia, thrombocytopenia);
- conducting hemodialysis;
- children under 5 years;
- individual intolerance of the drug.
Application in pregnancy and lactation
With caution and under the supervision of a doctor, it is possible to prescribe Wobenzym during pregnancy and lactation.
Use in children
Contraindicated in children under 5 years.
Children aged 5-12 years are prescribed in a daily dose of 1 tablet per 6 kg of body weight. Children older than 12 years of age, the drug is prescribed according to a scheme designed for adults. The duration of treatment is determined individually.
special instructions
It should be borne in mind that at the beginning of treatment with Wobenzym may exacerbate the symptoms of the disease. In such cases, it is recommended to temporarily lower the dose, treatment should not be interrupted.
With infectious and inflammatory diseases, Wobenzym does not replace antibiotic treatment, but increases their effectiveness.
Wobenzym is not doping.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not adversely affect the ability to drive a car and perform work that requires a high rate of psychomotor reactions.
Drug Interactions
With the simultaneous administration of Wobenzym with other drugs, incompatibility cases are unknown.
Analogues of the drug Wobenzym
Wobenzym does not have structural analogs for the active substance.
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