Pyrogenal - instructions for use, analogs, testimonials and release forms (injections in ampoules for injections, rectal suppositories 50 μg, 100 μg, 150 μg and 200 μg №5, 10 and 12) drugs for the treatment of adhesions, uveitis in adults, children and during pregnancy

In this article, you can read the instructions for using the drug Pyrogenal. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Pyrogenal in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Pyrogenal in the presence of existing structural analogs. Use to treat adhesions, uveitis and chronic prostatitis in adults, children, as well as during pregnancy and lactation.

Pyrogenal - immunomodulator of broad spectrum of action, activates reticuloendothelial, hypothalamic-pituitary and fibrinolytic systems. It has desensitizing and anti-inflammatory properties, increases the general and specific resistance of the body, affects the thermoregulatory centers of the hypothalamus.

Composition

Lipopolysahard, isolated from the bacteria Salmonella typhi + auxiliary substances.

Indications

• trauma of the central nervous system and peripheral nervous system;
• tuberculosis (torpid form in the resolution phase);
• chronic liver disease;
• stricture of urethra, ureter, chronic prostatitis, urethritis;
• uveitis, iridocyclitis, herpetic infection of the eye, corneal opacity;
• inflammation of the appendages of the uterus, infertility;
• Adhesive disease of abdominal cavity;
• burn disease;
• venereal diseases;
• psoriasis and other chronic skin diseases;
• specific provocation in case of examination for venereal diseases;
• for pyrotherapy.

Forms of release

Solution for intramuscular injection (injections in ampoules for injection).

Candles for rectal administration 50 μg, 100 μg, 150 μg and 200 μg in packages of 5, 10 and 12 pieces.

Other dosage forms, be it pills or syrup, are not registered.

Instructions for use and dosage

Ampoules

Intramuscularly once a day every other day, if necessary, the drug is diluted with 0.9% solution of sodium chloride.

The initial single dose is 0.2 μg, in the following days the dose is gradually increased by 2.5-5 μg.

The maximum single dose is 100 mcg. Full course - 10-30 injections, if necessary, it is possible to repeat the course - after 2-3 months.

For pyrotherapy - intramuscularly once a day, starting with 5-10 mcg with an increased dose to 100-150 mcg. Injections are carried out after 1-2 days.

Candles

Rectally, 1 suppository per day, every day or every other day, the initial dose is 50 μg, the maximum dose is 200 μg. The course of treatment - 12-15 suppositories. Treatment according to the scheme is recommended: 50, 50, 50, 100, 100, 100, 150, 150, 150, 200, 200, 200 mcg. When using suppositories in the form of monotherapy for immunorehabilitation in case of incomplete recovery after acute bacterial or viral disease, suppositories of 50 or 100 μg should be used. The course of treatment is 5-10 suppositories.

Possible simultaneous treatment with suppositories and intramuscular injections.

Treatment with pyrogenal

Injections: Starting at 5 μg / ml every other day, with an incremental rate of 5 μg / ml, 15-20 injections. The maximum single dose is 150 μg / ml.

Candles: Course 10-12 days, increasing course, daily.Either a set of 12 suppositories, or, according to the scheme:

Pyrogenal 50 μg - 3 days + Pyrogenal 100 μg - 3 days + Pyrogenal 100 μg + Pyrogenal 50 μg - 3 days + Pyrogenal 100 μg - 2-3 days = 12 days.

In a chronic course, the course is 24 days - Pyrogenal 50 μg - 6 days + Pyrogenal 100 μg - 6 days + Pyrogenal 100 μg + Pyrogenal 50 μg - 6 days + Pyrogenal 100 μg - 2-6 days = 24 days.

Side effect

• increase in body temperature to 37.5 ° C;
• chills;
• malaise;
• headache;
• back pain.

Contraindications

• acute febrile illness;
• chronic diseases in the stage of exacerbation and decompensation (with the exception of diseases that are an indication for the prescription of the drug);
• blood diseases;
• pregnancy.

Application in pregnancy and lactation

Contraindicated in pregnancy.

Use in children

In children, the dose is reduced in accordance with age; begin with the introduction of 5-15 IU, gradually increasing the dose, if necessary, but not exceeding 250-500 IU. The course of treatment - 10-15 injections.

special instructions

If intramuscular injection usually occurs within 3-8 h, hyperthermia, chills, malaise, then the dosage that caused this reaction is repeated on subsequent days (usually 1-3 days) until the reaction stops, after which the dose is consistently increased.

If within 6-8 h there is hyperthermia up to 39.5 ° C, severe chills, headache, back pain, then the dose of the drug is recommended to be reduced. When using the drug for pyrotherapy, the above reactions are acceptable.

If there is a convulsive readiness, the drug is prescribed against the background of anticonvulsant therapy.

Drug Interactions

The drug is compatible and well combined with all medicines used in the treatment of the diseases and conditions indicated in the indications. Strengthens the effectiveness of chemotherapeutic drugs in the complex therapy.

Analogues of the drug Pyrogenal

Structural analogues of the active substance of the drug Pyrogenal does not.

Analogues on the curative effect (agents for the treatment of adhesions):

• Longitude.

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