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Sulfadimethoxin - instructions for use, reviews, analogs and formulations (tablets 200 mg and 500 mg) drugs for the treatment of sore throat, sinusitis and otitis in adults, children and pregnancy. Composition

Sulfadimethoxin - instructions for use, reviews, analogs and formulations (tablets 200 mg and 500 mg) drugs for the treatment of sore throat, sinusitis and otitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Sulfadimethoxin. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Sulfadimethoxin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Sulfadimethoxin in the presence of existing structural analogs. Use for the treatment of sore throat, sinusitis and otitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

 

Sulfadimethoxin - antibacterial agent, a sulfonamide derivative. Has a long effect with ingestion. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of tetrahydrofolic acid necessary for the synthesis of purines and pyrimidines.

 

It is active against gram-positive bacteria: Staphylococcus spp. (Staphylococcus aureus), Streptococcus spp. (including Streptococcus pneumoniae) (streptococcus); Gram-negative bacteria: Klebsiella pneumoniae, Escherichia coli, Shigella spp.

 

It is active against Chlamydia trachomatis (chlamydia).

 

Composition

 

Sulfadimethoxin + auxiliary substances.

 

Pharmacokinetics

 

After oral administration after 30 minutes it is found in the blood. Poorly penetrates the blood-brain barrier (BBB). Therapeutic concentration in adults is noted when taking 1-2 g on the first day and 0.5-1 g in the following days. Unlike other sulfonamides, the preferential metabolism is carried out along the path of microsomal glucuronation associated with the isoenzymes CYP450 and NADPH-dependent.

 

Indications

 

Infectious-inflammatory diseases caused by microorganisms sensitive to sulfadimethoxin:

  • angina;
  • sinusitis;
  • otitis;
  • bronchitis;
  • dysentery;
  • inflammatory diseases of the biliary and urinary tract;
  • erysipelas;
  • wound infections;
  • trachoma.

 

Forms of release

 

Tablets 200 mg and 500 mg.

 

Instructions for use and dosage

 

Adults on the 1st day of treatment - 1 g, in subsequent days - 500 mg per day. In severe disease, the dose may be increased. Children on the first day of treatment - 25 mg / kg, in the following days - 12.5 mg / kg per day.

 

Take inside once a day after meals. Duration of treatment 7-10 days.

 

Side effect

  • headache;
  • dyspeptic symptoms;
  • nausea, vomiting;
  • cholestatic hepatitis;
  • skin rashes;
  • drug fever;
  • leukopenia, agranulocytosis.

 

Contraindications

  • hypersensitivity to sulfonamides;
  • oppression of bone marrow hematopoiesis;
  • renal and / or liver failure;
  • chronic heart failure;
  • congenital deficiency of glucose-6-phosphate dehydrogenase;
  • porphyria;
  • azotemia;
  • pregnancy.

 

Application in pregnancy and lactation

 

Sulfadimethoxin is contraindicated in pregnancy.

 

special instructions

 

During treatment, an abundant alkaline drink is recommended, monitoring the blood and urine.

 

It is applied externally as a part of combined preparations.

 

Drug Interactions

 

Sulfadimethoxin reduces the effectiveness of bactericidal antibiotics acting only on fissile microorganisms (including penicillins, cephalosporins).

 

Analogues of the drug Sulfadimethoxin

 

Structural analogues of the active substance of the drug Sulfadimetoksin does not.

 

Analogues on the pharmacological group (sulfonamides):

  • Arhedin;
  • Argosulfan;
  • Bactrim;
  • Bactrim forte;
  • Berlocid;
  • Biseptol;
  • Briefeptol;
  • Grosseptol;
  • Dapson Fatol;
  • Dvseptol;
  • Dermazin;
  • Duo Septol;
  • Inhaliptus;
  • Co-trimoxazole;
  • Cotripharm;
  • Lidaprim;
  • Methosulfabol;
  • Oriprim;
  • Polseptol;
  • Septrin;
  • Sinersul;
  • Streptonitol;
  • Streptocide;
  • Streptocide is soluble;
  • Streptocide Ointment 10%;
  • Sulotrim;
  • Sulgin;
  • Sulphadimezine;
  • Sulfalene;
  • Sulfamethoxazole;
  • Sulfanilamide;
  • Sulfargin;
  • Sulfasalazine;
  • Sulfacetamide;
  • Sulfacil sodium (Albucide);
  • Sumetrolim;
  • Trimezol;
  • Phthalazole;
  • Phthalylsulfatiazole;
  • Tsiplin;
  • Ethazol.

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Reviews (25):
Guests
Olya
For the umpteenth time I am convinced that people often use medicines in cheap paper packaging without the instructions attached to them for other purposes. It happened in our family, it's true, it's been a long time already.

In due time my mum has had been ill with a bronchitis, treated by the appointed or nominated therapist a preparation Sulfadimetoksin. Then he helped well. But at that time they had not heard about the Internet yet, and they did not attach instructions to this drug. Because the results of the action of the drug liked, Sulfadimetoksin settled in a home medicine chest. And since then they have treated every small cold in the Maldives, although it is not from a cold at all. However, in some incredible way, we, nevertheless, recuperated.

To taste, like the look, the tablets are not noticeable. None of our family noticed any side effects.
Guests
Lopatina Elena
Treated and still treated with sulfadimethoxin. Helps or assists well at any cold. smile winked
Guests
Yuri Dmitrievich
I am 80, cold symptoms kill sulfadimethoxin! I confirm.All active life!
Guests
николай васильевич 57 years
I tried in a dose of 1 g in the morning and 1 g in the evening. It's already the third day. Got better.
Guests
Irina
With catarrhal diseases I do not know the means of more effective than sulfadimethoxin. I do not really trust new fashionable preparations like all kinds of spikes that are expensive, while they remove symptoms, and do not eliminate the cause of the disease. Especially saves the drug with a dry cough. If it were not sulfadimethoxin, I do not even know what it can replace, because there are no analogues, the active substance is unique. And a definite plus is an affordable price.
Guests
Tatyana
Sulfadimetoksin was prescribed even before the collapse of the USSR and always quickly passed a cold and even a strong cold without the use of drops. I somehow forgot about him, but I got so cold that I had a dry cough and a bad cold. I do not really trust new drugs anymore. There are too many side effects from their reception. Of course, and the price plays a role - why pay large amounts and it is not yet known whether you will buy a fake.
Guests
Tatyana
The outbreak of colds and flu in the spring of 2015 did not pass me by. After skiing, my throat fell sharply. Within one day, the pain in the throat became worse, towards the evening the lymph node became inflamed and the pain spread to the left ear. In the evening the temperature is 38.5. I do not go to doctors for a long time, I use warming up of legs, balsam "asterisk", herbal teas and pork collection, honey, lemon, fruit for recovery. After warming up his legs in an hour, the pain in his ear subsided, remained only in the throat. For several days I tried to get rid of sore throat and cough by various means, then I was advised to take sulfadimethoxin. Bright results from him, I did not notice, but the allergy on the sixth day of admission showed up. I used the product according to the instructions. Has received: reddening of sites of a skin on fingers and an external side of brushes of hands, on cheeks and kolenjah, plus a strong itch. And I have never had an allergy in my life! So, be careful!
Guests
Marina Anatolyevna
Many years I am treated with sulfadimethoxin and nothing else. As it fell ill, the temperature for 39 shura, called the doctor.the doctor came and immediately prescribed an antibiotic for me (as I later learned in the drugstore, two tablets cost 460 rubles) I said that I was treated with sulfadimethoxin, she laughed, said that my kidneys and liver would fall off, that it was yesterday's drug. And most importantly, if I do not drink the antibiotic prescribed by her, she will write me a violation of the regime in the hospital! I sent her mentally far away, I did not immediately go crazy with antibiotics. After a few days, I stopped, without cough, the bronchitis was treated. I understand that doctors have collusion with pharmacies, but why should people be cured with antibiotics and frightened by non-existent consequences. So sulphadimethoxin for many years in our medicine cabinet. Good health to everyone!
Guests
Sergey Vladimirovich
Once in childhood, after multiple angina, doctors diagnosed chronic tonsillitis. After any cold, there was a sore throat, which intensified and passed only after taking sulfadimethoxin. So I strongly recommend all the sore throats.
Guests
NATALIA.
My mother is also treated for many years with sulfadimethoxin, and he always helps her.And she is already 84 years old and no side. But not in all pharmacies it is. I went around several pharmacies in Kazan and everywhere I was told that this drug is no longer used and has not been purchased for a long time. And in a small town, please, everywhere there is. And about conspiracy of doctors is no longer a secret. Immediately they spike us with expensive antibiotics, even with a mild ORZ. And then what's more serious, and antibiotics do not work anymore. And there is no justice for this lawlessness. Immediately threatened that they will not sign the sick leave.
Guests
Max
Helps perfectly, but strongly pronounced allergies to the face and genitals.
Guests
Mihailo
Better than all the clever!
Guests
Jeanne
From the student years, from the age of 75, one salvation is sulfadimethoxin for colds. With antibiotics it is better not to get involved - I had an allergic shock when taking antibiotic Glevo. Now it is dangerous to try new drugs, take what you know!
Guests
Nikolai from Lugansk ЛНР
Cured sulfadimetoksinom gum disease (the so-called flux): one tablet of 0.5 g per day. On the second day, virtually all manifestations of inflammation disappeared.I recommend to all!
Guests
Lyudmila
With new imported medicines, I'm with hr. Bronchitis was cured prior to COPD, a chronic lung disease. Once there was an exacerbation of the disease - at first they were treated out-patient. Then put in pulmonology and so about two months. In the hospital, I probably started an allergy and I was discharged with an open b. l. Turned to a friend she worked honey. sister in a tube. hospital. So I got an appointment with this doctor. A very old woman, I now do not remember her acting. and the girlfriend has already left, but the point is that the doctor was horrified, as my friend told me, during the treatment I took seven antibiotics-seven! And helped me cope at the time with the disease sulphadimethoxin and now I always, if I find this medicine I use it for the treatment of colds - it helps.
Guests
Lyudmila
Remarkably helped in those distant and troubled 90's. We are from the first shuttles, we arrived in a strange city, and I with a temperature by the evening. The girlfriend immediately responded and offered sulfadimethoxin. In the morning rose, as if nothing had happened. Save the God of those, then discovered this drug. Now I am flying to my granddaughter.
Guests
angar
Your dimethoxin did not help at all. From analogs I can only remember biseptol, the same useless dummy. I went to the doctor, prescribed sulphadimethoxin, drank ... As a result, after a week of this intensity, I got out a sore throat, now I sit on antibiotics and though I began to recover, than I went sick after the first medicine. Probably, foot and mouth disease is still treated, but now you need to be treated quickly, and not weeks on the hospital sit.
Guests
Natalia 62g.
Throughout my conscious life, I was treated for cold and flu only with sulfadimethoxin. Cheap drug and effective.
Guests
Lazarev Oleg Gennadievich
I have long been using sulfadimethoxin for both prevention and treatment of colds.
Guests
Lyudmila Valentinovna
In 1974, I fell ill with focal pneumonia, put in a hospital, and I have penicillin and monomycin allergy. The doctor treated the disease with sulfadimethoxin, I already forgot how many days I took the medicine, but after 20 days the X-ray showed clean lungs. Now to me of 65 years, but I till now treat colds sulfadimetoksinom, but thus I accept on 0,5 tablets.against allergies. Failures never happened. In what I am sure, so in the absence of fakes. Doctors prescribe very expensive drugs.
Guests
lads
I have spent my whole life with this sulfadimethoxin. Both children and grandchildren are being treated. Always in reserve I hold. We do not often in pharmacies, it happens.
Guests
Casting
An excellent product, quickly puts on its feet. We forgot about him, but in vain. The husband only escapes them from any colds and inflammations. And recently my mother, 75, was cured of otitis for 3 days by sulfadimethoxin. I advise everyone.
Guests
a guest
Yes, the drug is good, we are treated by the whole family, but, unfortunately, I had an allergy in the form of a rash and itching: (on the face and labia, very uncomfortable.) Background: The gynecologist prescribed candles, and I caught a cold and decided to heal and drink sulphadimethoxin. .. After that, it began., A couple of days ago, I was sick, completely forgot that the allergy and drank ... after half an hour on the same spot, spots and itching: (p
Guests
Irina Zhuravleva
Very often, from childhood I have colds. And so 6-7 years almost every winter - pneumonia. What did not I try. Doctors prescribe antibiotics, when I talk about this drug laugh, they say that it is a toxin - a poison. I believe, drink, call antibiotics according to their purpose, then I get to the hospital, they break it off .... and so several years in succession. But in the last two years I decided not to listen to doctors and as soon as the first signs of a cold - 4 tablets of sulfadimethoxin on the first day, 1 tablet on the second day and on the third I have a "cucumber" ... Better sulfadimethoxin does not help.
Guests
Zinaida, city of Krasnodon
In the summer I fell sick with genyantritis and tracheitis. She started treatment with sulfadimethoxin: 1 st day 1d, last. 0.5 g, washed the nose with saline. Five days later the disease was gone. Improvements were already on the second day.

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