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Guttalax - instructions for use, analogs, reviews and release forms (drops, tablets 5 mg) laxative drug for the treatment of constipation in adults, children and pregnancy. Composition

Guttalax - instructions for use, analogs, reviews and release forms (drops, tablets 5 mg) laxative drug for the treatment of constipation in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Guttalax. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Guttalaksa in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Guttalaksa in the presence of existing structural analogues. Use to treat constipation in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

 

Guttalax - laxative drug.The active substance - sodium picosulphate - is a laxative triarylmethane group.

 

As a local laxative, sodium picosulfate after bacterial cleavage in the large intestine has a stimulating effect on the mucosa of the colon, increasing peristalsis, contributing to the accumulation of water and electrolytes in the large intestine. This leads to stimulation of the act of defecation, a decrease in the time of evacuation and softening of the stool.

 

Composition

 

Sodium picosulphate monohydrate + auxiliary substances.

 

Pharmacokinetics

 

After oral administration, Guttalax enters the large intestine. Absorption of the drug is negligible, which excludes its enterohepatic circulation. In the colon, sodium picosulphate is split into an active metabolite. The time of development of the laxative effect of the drug is determined by the release rate of the active metabolite and is 6-12 hours. An insignificant part of the drug enters the systemic bloodstream.

 

The relationship between the laxative effect of the active metabolite and its concentration in serum is absent.

 

Indications

 

As a laxative in the following cases:

  • constipation due to atony and hypotonia of the colon (including in old age, in bedridden patients, after surgery, after childbirth and during lactation);
  • constipation caused by medication;
  • for the regulation of stool with hemorrhoids, proctitis, anal fissures (for softening the stool consistency);
  • diseases of the gallbladder, irritable bowel syndrome with a predominance of constipation;
  • constipation due to intestinal dysbiosis, diet disorders.

 

Forms of release

 

Drops for oral administration.

 

Tablets 5 mg.

 

Other forms, such as syrup or candles, do not exist.

 

Instructions for use and reception scheme

 

The drug is prescribed inside.

 

Adults and children over 10 years are prescribed 10-20 drops (5-10 mg); children 4-10 years - 5-10 drops (2.5-5 mg).

 

To get a laxative effect in the morning, the drug should be taken the night before.

 

Side effect

  • nausea, vomiting;
  • spasms and pains in the abdomen;
  • diarrhea;
  • dizziness;
  • fainting;
  • reactions of hypersensitivity from the immune system, including angioedema and skin reactions.

 

Contraindications

  • intestinal obstruction;
  • obstructive bowel disease;
  • acute inflammatory bowel disease;
  • severe abdominal pain accompanied by nausea and vomiting, which may be a symptom of the above-mentioned severe conditions;
  • severe dehydration;
  • children under 4 years;
  • hypersensitivity to sodium picosulphate and other components of the drug.

 

Application in pregnancy and lactation

 

There are no data on reliable and well-controlled studies in pregnant women. Long-term experience of use has not revealed a negative effect of the drug on pregnancy. Taking the drug in the first trimester of pregnancy is contraindicated.

 

In the 2nd and 3rd trimesters of pregnancy (as with other laxatives), the drug is taken only by the doctor's prescription.

 

Studies on the effect of the drug on fertility have not been conducted. During pre-clinical studies, there were no teratogenic effects on reproductive performance.

 

Use in children

 

Contraindicated in children under 4 years.

 

special instructions

 

It is not recommended to take the drug daily without consulting a doctor for more than 10 days. Long-term use of the drug in high doses can lead to dehydration, disruption of electrolyte balance, hypokalemia.

 

In folk medicine there is an opinion about the advisability of taking Guttalax as a means of losing weight. This appointment is not justified, since the effect will be short-lived (while this drug is being taken).

 

Dizziness and fainting were observed in patients taking Guttalax. The analysis showed that these cases are associated with fainting during defecation (or a syncope caused by stress during defecation) or with a vasovaginal response to abdominal pain that may be caused by constipation and is not necessarily associated with taking the drug.

 

In 1 ml drops contains 450 mg of sorbitol. The maximum recommended daily dose for treatment of adults and children 4-10 years old contains 600 mg and 300 mg of sorbitol, respectively.

 

The drug does not have taste, so children can add it to food. Children should take the drug only as directed by the doctor.

 

Impact on the ability to drive vehicles and manage mechanisms

 

Special clinical studies of the effect of the drug on the ability to control the car and mechanisms were not carried out. Despite this, patients should be informed that they have a vasovagal reaction (i.e.during a spasm of the intestine) dizziness and / or fainting may occur. If patients develop a spasm of the intestine, they should avoid potentially dangerous activities, incl. driving vehicles or controlling machinery.

 

Drug Interactions

 

With the simultaneous use of Guttalax in high doses and diuretics or glucocorticosteroids (GCS), the risk of developing electrolyte disorders (hypokalemia) is increased.

 

Simultaneous administration of antibiotics can reduce the laxative effect of Guttalax.

 

Violation of electrolyte balance can increase sensitivity to cardiac glycosides.

 

Analogues of the drug Guttalaks

 

Structural analogs for the active substance:

  • Guttasil;
  • Laxigal;
  • Regulax Picosulphate;
  • Slabicap;
  • It's weak.

 

Analogues for the pharmacological group (laxatives):

  • Agiolax;
  • Bisacodyl;
  • Vaseline oil;
  • Glaxen;
  • Glycelax;
  • Glycerol;
  • Good luck;
  • Depurablux;
  • Dr. Theiss Nova figure;
  • Dulcolax;
  • Dufalac;
  • Gastric collection number 3;
  • Castor oil;
  • Clam;
  • Buckthorn bark;
  • Lavakol;
  • Lactitol monohydrate;
  • Lactulose;
  • Kelp;
  • The Legend;
  • LIVOVOK PB;
  • Lizalak;
  • Flax seeds;
  • Mikrolaks;
  • Milk of magnesia;
  • Mukofalk;
  • Naturoolax;
  • Norgalax;
  • Normase;
  • Osmogol;
  • Pursennid;
  • Realaksan;
  • RectActive;
  • Romfalak;
  • Senadé;
  • Senadexin;
  • Senales;
  • Senna;
  • Sennalax;
  • Slabicap;
  • Laxative collection;
  • Licorice root;
  • Software;
  • Thyssen;
  • Transulose;
  • Forlax;
  • Fortez Rompharm;
  • Fortrans;
  • Endofalk;
  • Enema Klin.

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Reviews (7):
Guests
Alina
Because of the peculiarities of the work, often have to chew on the go. Naturally, about any first dishes we are not talking, rolls with yogurt, yes sandwiches with mineral water - my main lunches. As a consequence - constipation.

To re-evaluate the diet does not work, and I did not want to drink laxatives, because I know about their, often, painful action. But a colleague with a similar delicate problem shared her recipe for getting rid of it.Very praised drug guttalaks just for the softness and painlessness of the action. Me this tool also came up. In the evening I accept, early in the morning the problem is solved.

It should be noted that the drug can be taken daily for a short time, up to 10 days. But plus guttalaksa is that he not only weakens, but normalizes the stool. Therefore, it is not necessary to take it every day. I'm missing 2-3 times a week. I have been taking it for more than 3 months. Neither the expressed taste, nor a smell this medicine does not have. In general, no discomfort, the action of the drug is very satisfied. It is worth, however, a little expensive.
Guests
Anna Petrovna
Constipations suffer often, so I try to take different drugs from constipation. Guttalax is in my medicine cabinet. I drip to 15 - 20 drops in a glass of water and drink in the evening. In the morning, everything is in order with a chair. I did not notice any spasmodic pains, nausea or vomiting, and other reactions of the body to the drug.
Guests
Saranova
I am saved from constipation by candles RectActive from an extract of dry horse chestnut.Excellent, natural laxative, helped me many times already.
Guests
Yulka
Representatives and / or distributors of the company RectActive I give you a warning for advertising your drug in reviews, and besides to other medicines. Have a conscience and respect for other members of the pharmacy and consumers.
admin
Guests
OLGA
Me too the preparation approaches or suits. Still, it should be taken with some periodicity (you need to choose for yourself this regime) if you have it chronically, and not sporadically. Well, plus myself to do something, so that the intestines still try to work themselves.
Visitors
Lara Iris
Dear admin, we have this problem. His father (he is 79 years old) four months ago began to suffer regular constipation. And only a month ago somehow convinced him to be examined. He passed all the tests, FGS, ultrasound of the organs of the abdominal cavity (they found 2 stones 2 cm in the gall, but this never bothered him) - all organs within the norm by age. Only constipation is painful, but nothing hurts. An entry to the proctologist is in the middle of March. It is saved only by guttalaks (drops) in 2-3 days.Very much I worry, whether it is harmful to so often drink guttalaks, whether there can be any problems because of this medicine? In March, I hope the pope will be diagnosed at last and prescribe a treatment, but for now our therapist staunchly remains silent ... Maybe something else will be advised?
Administrators
admin
Lara IrisUntil March, these are not years, you can poprinimat, because to suffer from chronic constipation and doing nothing it would be worse than to stimulate defecation, albeit regularly. Examination - this is correct, the cause should be looked for, because if there was a trivial reason, it would be enough for a couple of days of taking Gutalax, and then there was a normalization of the stool. You can try more drugs based on lactulose (Dyufalak, Normase and others). If the problem is in the intestinal flora, a similar replacement can help. Most likely the reason in the atony of the intestine, this is possible with age, so it is possible after the proctologist will have to turn to the gastroenterologist, for diagnosis and treatment.

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