Karipazim - instructions for use, analogs, reviews and release forms (lyophilizate for the preparation of a solution, ointment, gel or cream) of a medicinal product for the treatment of burns in adults, children and during pregnancy
In this article, you can read the instructions for using the drug Caripazim. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of caripazim in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of caripazime in the presence of existing structural analogues. Use to treat burns (to accelerate the removal of scabs and wounds) in adults, children, as well as during pregnancy and lactation.
Caripazim - a proteolytic agent for external use, cleaves necrotic tissues, dilutes viscous secrets, exudate, blood clots.
By action it is close to chymotrypsin and trypsin.
Composition
Enzymes from dried papaya milk paste (papain, chymopapain A, chymopapain B, peptidase A and B, lysozyme - mucolytic enzyme), with total proteolytic activity + auxiliary substances.
Pharmacokinetics
When applied externally, the drug is not absorbed and does not have systemic effects on the body. The enzymes that make up Karipazima are destroyed and completely biotransformed in the liver.
Indications
- burns 3a degree (to accelerate the rejection of the strings and purification of granulating wounds from the remains of purulent-necrotic tissues).
Forms of release
Liofilizate for the preparation of a solution for external use 350 PE and 700 PE.
There are no other forms, be it ointment, cream or gel.
Instructions for use and how to use them
Outer, in the form of solutions with concentrations of 17.5 PE / ml, 35 PE / ml or 70 PU / ml, depending on the thickness of the scab. Solutions are prepared on 0.5% solution of novocaine or 0.9% isotonic sodium chloride solution.A tissue moistened with a drug is applied to the burn surface, covered with a waterproof bandage. At the same time, no more than 30% of the total body surface is treated. The bandage is changed once a day or 1 time in 2 days, while removing the exfoliated necrotic tissue. The course of treatment is 4-12 days.
Side effect
- allergic reactions.
Contraindications
- increased individual sensitivity to the drug;
- pregnancy;
- lactation period.
Application in pregnancy and lactation
Contraindicated to use the drug Karipazim during pregnancy and lactation.
special instructions
The drug has no adverse effect on the ability to drive a car and work with machinery.
Drug Interactions
Clinically significant interactions of caripazim with other drugs have not been established.
Analogues of the drug Karipazim
Structural analogs for the active substance:
- Papain.
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