Tizin - instructions for use, reviews, analogs and forms of release (nasal drops 0.1%, nasal spray 0.05% and 0.1% Xylo and Xylo Bio) drugs for the treatment of cold in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Tysin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Tizin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tizin in the presence of existing structural analogues. Use to treat the common cold in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Tysin - sympathomimetic. When topical application causes vasoconstrictive effect, which develops after a few minutes and persists for a long time.

Tizin Xylo Bio is a vasoconstrictive drug for topical application in ENT-practice. Xylometazoline (imidazole derivative) - alpha-adrenomimetic, narrows the blood vessels of the mucous membrane of the nasal cavity, eliminating edema and hyperemia of the mucous membrane. Relieves nasal breathing in rhinitis. Hyaluronic acid, which is part of the preparation, has a moisturizing effect when used in nasal medicines due to its ability to maintain mucous membranes in a moistened state and creates optimal conditions for reconstructive processes.

The action usually develops within 5-10 minutes.

Composition

Tetrisolin + excipients (Tysin).

Xylometazoline hydrochloride + excipients (Xylo and Xylo Bio).

Pharmacokinetics

With topical application, systemic absorption is low.

Indications

• slight eye irritation;
• itching, swelling and congestion hyperemia;
• burning, lacrimation, injected sclera due to chemical and physical factors (dust, cosmetics,swimming in chlorinated water, the action of bright light);
• allergic conjunctivitis;
• to reduce the edema of the nasopharyngeal mucosa and secretions in acute allergic rhinitis, acute respiratory disease with rhinitis, sinusitis, pollinosis, otitis media;
• preparation of patients for diagnostic manipulation in the nasal passages.

Forms of release

Drops in the nose 0.1%.

Spray nasal 0.05% and 0.1% (Tizin Xylo and Xylo Bio).

Instructions for use and how to use them

Spray nasal

Tysin Xylo and Bio in the form of a nasal spray 0.05% are prescribed for children aged 2 to 6 years, 1 dose per each nasal passage 1-2 times a day.

Tizin Xylo and Bio in the form of nasal spray 0.1% are prescribed for adults and children over 6 years for 1 dose in each nasal passage 3 times a day.

The dose depends on the individual sensitivity of the patient and the clinical effect.

Do not use the drug for more than 5-7 days without a doctor's recommendation.

After completion of therapy, the drug can be re-administered only after a few days.

The duration of the drug in children is determined by the doctor.

Application rules

Remove the protective cap. Before using for the first time, press the spray nozzle several times beforeuniform cloud of "fog". The bottle is ready for use. When using, press 1 time. The drug is inhaled through the nose. If possible, keep the spray bottle vertically. Do not spray horizontally or downward. After use, the bottle should be closed with a cap.

Side effect

• transient mild irritation of the nasal cavity (burning) in susceptible people;
• sneeze;
• increased swelling of the nasal mucosa (reactive hyperemia);
• headache;
• insomnia;
• impaired vision;
• fatigue and depression (with prolonged use in high doses);
• palpitation;
• tachycardia;
• arrhythmia;
• increased blood pressure.

Contraindications

• simultaneous administration of MAO inhibitors or other drugs that increase blood pressure;
• tachycardia;
• glaucoma;
• atrophic rhinitis;
• surgical interventions on the meninges (in the anamnesis);
• thyrotoxicosis;
• patients with severe cardiovascular diseases (eg, ischemic heart disease (including angina pectoris), tachycardia, arterial hypertension, severe atherosclerosis);
• patients with surgical interventions on the meninges in the anamnesis;
• Children under 6 years of age (for nasal spray 0.1%);
• Children under 2 years of age (for nasal spray 0.05%);
• hypersensitivity to any of the components of the drug.

Application in pregnancy and lactation

Xylometazoline should not be used during pregnancy; Effects on the fetus in clinical studies have not been studied.

The drug should not be used during breastfeeding. it is not known whether the active substance is excreted in breast milk.

special instructions

Long-term use and overdose of sympathomimetics, which have a decongestive effect, can lead to reactive hyperemia of the nasal mucosa. As a result, there is difficulty in nasal breathing, which leads to the fact that the patient begins to use the drug repeatedly or even constantly. This can lead to chronic swelling (medicamentous rhinitis), and eventually even to the atrophy of the mucous membrane of the nose (ozena).

In more mild cases, in order to improve the patient's condition, one can first stop the introduction of sympathomimetics into one nasal passage, and after reducing complaints continue to inject it into the other nasal passage to partially provide nasal breathing.

The patient should be informed that if the drug has become unusable or has expired, then do not throw it into sewage or into the street.It is necessary to place the drug in a bag and put it in a garbage container. These measures will help protect the environment.

Impact on the ability to drive vehicles and manage mechanisms

With prolonged treatment or use of the drug in higher doses, one can not exclude the possibility of its systemic action on the cardiovascular system. In such cases, the ability to drive and use machinery may be impaired.

Drug Interactions

Simultaneous use of MAO inhibitors such as tranylcypromine or tricyclic antidepressants may lead to an increase in blood pressure due to the cardiovascular effects of these substances.

Analogues of the drug Tysin

Structural analogs for the active substance:

• Berberil N;
• Vizin;
• Classical Vizin;
• VisOptic;
• Montevizine;
• Octilia.

Analogues on the curative effect (remedies for catarrh):

• 4 Wei;
• Abisil;
• AquaMaris;
• Aqualor Baby;
• Aqualor norms;
• Arthromax;
• Aspirin Complex;
• Bioparox;
• Vibrocil;
• Halazolin;
• Glycodine;
• Grippostad Rino;
• Influenza from the cold and flu;
• Derinat;
• Children's Tylenol for colds;
• Fornos;
• Isophra;
• Insty;
• Influenza;
• Cold storage;
• Koldar;
• Coldrex MaxGripp;
• Corizal;
• Xylen;
• Xylometazoline;
• Ximelin;
• Libexin Muko;
• Lordestin;
• Marimer;
• Mentoclar;
• Morenezal;
• Nazivin;
• Nasol;
• Knoxprey;
• Pinosol;
• Prostudox;
• Rhinisap with vitamin C;
• Rinonorm;
• Rinoprint;
• Rinoflumacil;
• Romazulan;
• Sanorin;
• Snoop;
• Suprastinex;
• Tizin Xylo;
• Tizin Xylo Bio;
• Toff plus;
• Umcalor;
• Fatal;
• Pharmazoline;
• Fervex spray from the cold;
• Physiomer spray nasal;
• Fluviert;
• Fluidite;
• Fluxcludex H;
• Fugentin;
• Humer;
• Erdomed;
• Erespal;
• Euphorbium.

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