Negra - instructions for use, reviews, analogs and form of release (tablets 500 mg) drugs for the treatment of cystitis, pyelonephritis and other infectious and inflammatory diseases in adults, children and pregnancy

Negra - instructions for use, reviews, analogs and form of release (tablets 500 mg) drugs for the treatment of cystitis, pyelonephritis and other infectious and inflammatory diseases in adults, children and pregnancy

In this article, you can read the instructions for using the drug The Negroes. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of the Negro in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of the Negroes in the presence of existing structural analogues. Use for the treatment of cystitis, pyelonephritis and other infectious and inflammatory diseases in adults, children,as well as during pregnancy and lactation.


The Negroes - antibacterial drug from the group of quinolones. Has a bactericidal or bacteriostatic effect, depending on the sensitivity of the pathogen and concentration. The mechanism of action is to suppress the synthesis of bacterial DNA by inhibiting the polymerization process.


It is active against Escherichia coli, Salmonella spp., Shigella spp., Proteus spp., Klebsiella spp. To a preparation strains of microorganisms resistant to antibiotics and sulfonamides are sensitive. Not active against gram-positive and anaerobic bacteria.




Treatment of infectious-inflammatory diseases caused by microorganisms sensitive to the preparation:

  • pyelonephritis;
  • cystitis;
  • urethritis;
  • prostatitis;
  • infections of the digestive tract;
  • cholecystitis.


Forms of release


Tablets of 500 mg.


Instructions for use and dosing regimen


The drug is prescribed to adults 1 g 4 times a day for 7 days. With a longer treatment, the dose can be reduced to 500 mg 4 times a day.


Children aged 2-12 years are prescribed in the initial daily dose of 60 mg / kg body weight; maintenance dose is 30 mg / kg / daily dose should be taken in 3-4 divided doses.


Side effect

  • nausea, vomiting, diarrhea;
  • gastralgia;
  • gastrointestinal bleeding;
  • cholestasis;
  • drowsiness;
  • headache;
  • dysphoria;
  • visual impairment and color perception;
  • convulsions;
  • skin rash, itching, angioedema;
  • thrombocytopenia, leukopenia, hemolytic anemia.



  • impaired liver function;
  • impaired renal function (QC less than 50 ml / min);
  • epilepsy;
  • severe form of atherosclerosis of the brain;
  • deficiency of glucose-6-phosphate dehydrogenase;
  • children under 2 years;
  • pregnancy;
  • increased sensitivity to nalidixic acid and other quinolones.


Application in pregnancy and lactation


Contraindicated the appointment of the drug during pregnancy. During lactation, use with caution, only in cases where the expected therapeutic effect for the mother exceeds the potential risk of side effects in the infant.


special instructions


If treatment is continued for more than 2 weeks, liver and kidney function should be monitored.


In case of serious side effects on the part of the CNS (increased intracranial pressure, psychotic reactions, convulsions) or allergic reactions (skin rash, photosensitization), taking Negram should be discontinued.


Treatment Negrum should be interrupted in the case of arthralgia in children and adolescents.


During the period of taking Negra, patients are advised to avoid prolonged exposure to the sun.


Against the backdrop of the application of Negrum, a false positive urine reaction to glucose is possible with a reduction method of determination, as well as falsely high values ​​of 17-ketosteroids in the urine.


Impact on the ability to drive vehicles and manage mechanisms


During treatment with Negrum, one should refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.


Drug Interactions


You should not appoint Negroes at the same time as indirect anticoagulants.


With the simultaneous use of Negrum with ethanol or drugs depressing the central nervous system, the depressing effect on the central nervous system can be intensified.


Negro is incompatible with nitrofurans.


Analogues of the medicinal product of Negra


Structural analogs for the active substance:

  • Nevigramon.

Similar medicines:

Other medicines:

Reviews (8):
Dr. Doolittle
Rare to use antibiotic.
Negroes for me are always prompt help, as soon as the old cystitis begins to bother. I will not hide that when I first started taking this drug, there were some side effects like drowsiness. But after a week she passed, the only thing that needs to be paid attention to interaction with other medicines, but this can always be discussed with the attending physician.
My daughter at 4.5 years old in the St. Vladimir Hospital was fed horse doses of black, she developed a toxico-allergic reaction. At first the face was swollen, then she screamed in pain from the joints, then stopped rising to her feet. Thanks to the doctors of the Morozov hospital for good treatment and treatment, my daughter recovered. The truth after all has sharply typed weight.
ELENA58, Moved your question to the drug Prediizin, where it is more appropriate.
I found out Pyelonephritis. I just did not understand what was happening to me ... I thought it was prostatitis, adenoma ... But when urine was not just blood, but bloody and blood clots, then I turned to the diagnostic system and received Pyelonephritis. Here tomorrow I'll buy the Negroes, and I'll start taking them urgently! I planned to buy Negra tomorrow, but I found out as a result of the search that in the pharmacies of Moscow it simply does not exist.
Vladimir.ONIt is possible to use the analogue of Negrum drug Nevigramon, but he now for some unrealistic price began to be sold. So I would not apply to the diagnostic system (there are no full-fledged systems at the moment, everyone sins with the completeness of the information provided and the quality of remote diagnostics), and to the urologist and the results of tests and examinations you would be given an accurate diagnosis and assigned a treatment.
admin, Many thanks! Would you recommend a normal urologist in the Eastern District of Moscow, Novogireevo district? Thank you.
Vladimir.ONUnfortunately, I do not subconscious. It has long been already territorially not in Moscow.

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