Cyclomed - instructions for use, reviews, analogs and formulations (eye drops 1%) of the drug for the treatment of keratitis, uveitis and iridocyclitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Cyclomed. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Cyclomed in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Cyclomed in the presence of existing structural analogues. Use for the treatment of keratitis, uveitis and iridocyclitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Cyclomed - m-holinoblokator.Blocking m-holinoretseptory, prevents the action of the mediator of cholinergic synapses - acetylcholine.

As a result of blocking the cholinergic synapses located in the pupil sphincter and ciliary muscle, the pupil dilates due to the predominance of the muscle tone that dilates the pupil and relaxes the muscle that narrows the pupil. Simultaneously, due to relaxation of the ciliary (accommodative) muscle, a paresis of accommodation (cycloplegia) occurs.

Dilation of the pupil occurs within 15-30 minutes after a single instillation. Mydriasis persists for 6-12 hours, in particularly sensitive patients, mild mydriasis can last much longer. Residual phenomena of cycloplegia persist for 12-24 hours.

The drug has a weak spasmolytic effect, increases intraocular pressure, reduces the tone of the vagus nerve, which leads to an increase in heart rate with a slight increase in blood pressure, it is also possible to reduce the secretion of salivary, gastric, bronchial glands and pancreas. Penetrating through the blood-brain barrier (BBB), in moderate therapeutic doses has a moderate stimulating effect on the central nervous system (in high doses has an exciting effect on the cortex of the headbrain, as a narcotic drug (drug), so it is released by prescription), stimulates the respiratory center.

Composition

Cyclopentolate hydrochloride + auxiliary substances.

Pharmacokinetics

Well absorbed through the conjunctiva. The detectable concentration in the central nervous system is reached after 0.5-1 h. Binding to plasma proteins is moderate.

Indications

• for the purpose of diagnosis with ophthalmoscopy and determination of refraction;
• in ophthalmic surgery - in preoperative preparation for the purpose of dilating the pupil in the extraction of cataracts;
• in the complex therapy of inflammatory diseases of the anterior part of the eye (episcleritis, scleritis, keratitis, iridocyclitis, uveitis).

Forms of release

Eye drops 1%.

There are no other forms, be it drops in the nose or pills.

Instructions for use and dosing regimen

Apply topically, by digesting into the conjunctival sac 1-2 drops.

For examination of the fundus, as a rule, 1-3-fold instillation is sufficient for 1 drop with an interval of 10 minutes.

When examining refraction in children and adolescents appoint 1-2 drops in 15-20 minutes 2-3 times a day.

In inflammatory diseases, eyes are prescribed 1 drop of 3, in severe cases, the drug is allowed to apply 1 drop every 3-4 hours.

When instillating the solution into the conjunctival sac, it is advisable to press the lower lacrimal point to avoid getting the solution into the nasopharynx.

Side effect

• redness of the conjunctiva and a feeling of discomfort after instillation;
• temporary decrease in visual acuity;
• increased intraocular pressure in patients with primary glaucoma;
• weakness;
• nausea;
• dizziness;
• tachycardia;
• drowsiness;
• dry mouth;
• headache.

Contraindications

• glaucoma or suspicion of its presence;
• post-traumatic paresis of musculus sphincter pupillae of the iris;
• hypersensitivity to cyclopentolate and other components of the drug.

Application in pregnancy and lactation

Data on the safety of Cyclomed in pregnant women and nursing mothers is currently insufficient, so the use of the drug is only possible in cases where the expected benefit of therapy for the mother exceeds the risk of possible side effects in the fetus or infant.

Use in children

With caution should prescribe the drug to children under the age of 3 years.

In children with a semi-stable or persistent spasm of accommodation for cycloplegia, it is more effective to apply the instillation courseatropine sulfate.

special instructions

Cyclomed is less effective in individuals with dark iris pigment. In these individuals, with the use of the drug, residual accommodation can reach 2.0-4.0 D.

In elderly patients, the use of Cyclomed requires monitoring of intraocular pressure.

Patients with hypersensitivity to atropine sulfate, do not give a cross-allergy to Cyclomed, which allows using it in this category of patients.

Impact on the ability to drive vehicles and manage mechanisms

Against the background of the use of the drug, it is necessary to refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Drug Interactions

The effect of Cyclomedum may be enhanced by sympathomimetics (mezaton), weakened by m-cholinomimetics (pilocarpine).

Preparations with m-holinoblokiruyuschimi properties while using the same can increase the side effects of Cyclomed.

Analogues of the drug Cyclomed

Structural analogs for the active substance:

• Cycloptic.

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