Etamzilat - instructions for use, analogs, testimonials and release forms (250 mg tablets, injectable injections) of a medicament for the treatment of bleeding with menstruation, in surgery and dentistry in adults, children and pregnancy

In this article, you can read the instructions for using the drug Etamsylate. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Etamsylate in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Ethamylate analogues in the presence of existing structural analogues.Use to treat bleeding with menstruation, in surgery and dentistry in adults, children, as well as during pregnancy and lactation.

Etamsylate - antihemorrhagic means. Normalizes the permeability of the vascular wall, improves microcirculation. The effect is apparently associated with an activating effect on the formation of thromboplastin. Does not affect prothrombin time, does not possess hypercoagulable properties and does not promote formation of thrombi.

The onset of action is 5-15 minutes after intravenous injection, the maximum effect is 1-2 hours after the injection. The duration of the action is 4-6 hours.

Composition

Etamsylate + auxiliary substances.

Pharmacokinetics

About 72% of the administered dose is excreted in the urine for the first 24 hours unchanged. Penetrates through the placental barrier, excreted in breast milk.

Indications

• prevention and treatment of capillary bleeding in diabetic angiopathies, surgical interventions in otolaryngology, ophthalmology, dentistry, urology, surgery and gynecology;
• emergency cases with intestinal and pulmonary hemorrhages, with hemorrhagic diathesis.

Forms of release

Tablets 250 mg.

Solution for intravenous and intramuscular injection (injections in ampoules for injection).

Instructions for use and dosage

When ingestion - 250-500 mg 3-4 times a day, intramuscularly or intravenously - 125-250 mg 3-4 times a day. If necessary, a single dose for oral administration can be increased to 750 mg, for parenteral administration up to 375 mg.

Children - 10-15 mg / kg per day, the frequency of application - 3 times a day in equal doses.

For external use, a sterile swab impregnated with etamzilate (in the form of an injection solution) is applied to the wound.

Side effect

• heartburn;
• feeling of heaviness in the epigastric region;
• headache;
• dizziness;
• hyperemia of the face;
• a decrease in systolic blood pressure;
• paresthesia of the lower extremities.

Contraindications

• thromboses;
• thromboembolism;
• increased sensitivity to etamzilate.

Application in pregnancy and lactation

When pregnancy is possible, if the expected effect of therapy exceeds the potential risk to the fetus (safety of etamzilate in pregnancy is not established). For the duration of treatment, breastfeeding should be discontinued.

Use in children

The application is possible according to the dosing regimen.

special instructions

Etamsylate can not be used as the only remedy if the patient has haemorrhages caused by anticoagulants.

Drug Interactions

Pharmaceutically incompatible with other medicinal products. Do not mix in the same syringe with other drugs.

The combination with aminocaproic acid, menadione sodium bisulfite is acceptable.

Analogues of the drug Etamsylate

Structural analogs for the active substance:

• Dicycin;
• Etamzilate Ferein;
• Etsamilat Eskom;
• Etamsylate injection 12.5%.

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