Tempalgin - instructions for use, analogs, reviews and release forms (tablets) of an anesthetic drug for the treatment of headaches and toothaches in adults, children and pregnancy. Composition and interaction with alcohol

In this article, you can read the instructions for using the drug Tempalgin. Comments of visitors of the site - consumers of this medication, as well as opinions of specialists on the use of Tempalgina in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tempalgin with existing structural analogues.Use of an anesthetic for the treatment of headache and toothache in adults, children, as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.

Tempalgin - an analgetic-antipyretic with a combined composition. Has analgesic, antipyretic, mild anti-inflammatory and sedative effect. The composition of the drug includes the non-opioid analgesic metamizole sodium and anxiolytic (tranquilizer) tempidone.

Composition

Metamizole sodium + Triacetonamine 4-toluenesulfonate (tpididone) + auxiliary substances.

Indications

• moderately or weakly expressed pain syndrome (including headache, migraine, toothache, neuralgia, radicular syndrome, myalgia, arthralgia, algodismenorea), especially in patients with increased nervous excitability;
• mild pain of visceral origin (including renal, hepatic, intestinal colic) in combination with spasmolytic therapy;
• pain syndrome after surgical and diagnostic interventions (as an adjuvant);
• increase in body temperature with colds and other infectious and inflammatory diseases.

Forms of release

The tablets covered with a cover.

Instructions for use and dosing regimen

Tablets are taken orally, without chewing, with a sufficient amount of liquid, during or after a meal.

Adults appoint 1 tablet 1-3 times a day, with insufficient effectiveness, you can take another 1 tablet. The maximum single dose is 2 tablets, the maximum daily - 6 tablets Duration of admission - no more than 5 days. An increase in the daily dose or an increase in the duration of treatment is possible only under the supervision of a physician.

Side effect

• burning sensation in the epigastric region;
• dry mouth;
• cholestasis;
• jaundice;
• headache;
• dizziness;
• hallucinations;
• decrease or increase in blood pressure;
• tachycardia;
• cyanosis;
• agranulocytosis, leukopenia, thrombocytopenia;
• oliguria;
• anuria;
• proteinuria;
• interstitial nephritis;
• staining the urine in red;
• skin rash;
• itching;
• urticaria (including conjunctiva and mucous membranes of the nasopharynx);
• angioedema;
• multi-form exudative erythema (including Stevens-Johnson syndrome);
• toxic epidermal necrolysis (Lyell's syndrome);
• bronchospasm;
• anaphylactic shock.

Contraindications

• severe hepatic impairment;
• severe renal failure;
• chronic heart failure;
• arterial hypotension (decrease of systolic blood pressure below 100 mm Hg);
• oppression hemopoiesis (granulocytopenia, leukopenia, agranulocytosis, cytostatic or infectious neutropenia);
• deficiency of glucose-6-phosphate dehydrogenase;
• "aspirin" asthma;
• pregnancy;
• lactation period (breastfeeding);
• children's age (up to 14 years);
• increased sensitivity to metamizole sodium, pyrazolone derivative or triacetonamine-4-toluenesulfonate.

Application in pregnancy and lactation

The drug is contraindicated for use in pregnancy. Do not use the drug during lactation, tk. both components are excreted in breast milk.

special instructions

Radiocontrast preparations, colloidal blood substitutes and penicillin should not be prescribed with metamizole sodium.

Do not drink alcohol while taking this medication.

The use of the drug in patients receiving cytotoxic drugs should be performed only under the supervision of a doctor.

Against the background of the use of Tempalgina, the development of agranulocytosis is possible, in connection with which, when an unclear genesis of fever, chills,pain in the throat, difficulty swallowing, stomatitis, as well as in the development of the phenomena of vaginitis or proctitis, drug withdrawal is necessary.

With prolonged (more than 7 days) taking the drug, you need to monitor the blood picture and the functional state of the liver.

It is inadmissible to use Tempalgine to relieve acute pain in the abdomen (until finding out the cause).

Impact on the ability to drive vehicles and manage mechanisms

In connection with the anxiolytic effect of the drug during the period of Tempalgina intake, one should refrain from engaging in potentially dangerous activities requiring increased attention and speed of psychomotor reactions.

Drug Interactions

Tempalgin enhances the effects of ethanol (alcohol).

Simultaneous application of Tempalgine with chlorpromazine or other phenothiazine derivatives may lead to the development of severe hyperthermia.

Sedatives and tranquilizers increase the analgesic effect of the drug.

With simultaneous use of thiamazole and cytotoxic drugs increase the risk of developing leukopenia.

With the simultaneous use of metamizole sodium with cyclosporine, the concentration of the latter in the blood plasma decreases.

Metamizole sodium, displacing from the bond with protein oral hypoglycemic drugs, indirect anticoagulants, glucocorticosteroids (GCS) and indomethacin, increases their effect.

With the simultaneous use of barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole sodium.

The simultaneous use of metamizole sodium with other non-opioid analgesics, tricyclic antidepressants, oral contraceptives, Allopurinol may lead to a mutual enhancement of toxic effects.

Codeine, histamine H2-receptor blockers and Propranolol slow the excretion of metamizole sodium and enhance its effect.

Analogues of the drug Tempalgin

Structural analogs for the active substance:

• Tempanginol.

Analogues on the pharmacological group (means for relief of headache and migraine):

• Aviton;
• Alisat;
• Allikor;
• Amigrenin;
• Amylonosar;
• Amitriptyline;
• Analgin;
• Anaprilin;
• Andipal;
• Ascofen;
• Aspirin-C;
• Acetaminophen;
• Betalk;
• Bromazepam Lannacher;
• Brustan;
• Burana;
• Vasocardine;
• Valerian;
• Vero Anadrilin;
• Vinpotropil;
• Histaglobin;
• Grippostad;
• Diltzer;
• Dimephosphone;
• Ditamin;
• Ibufen;
• Imigran;
• Inderal;
• Ipronal;
• Cardiomagnet;
• Caffetin;
• Contamnol;
• Cofetamine;
• Coffedon;
• Xantinol nicotinate;
• Kudevita;
• Lexotan;
• Metovit;
• MIG 200;
• MIG 400;
• Nalgezin;
• Nalgezin forte;
• Naramig;
• Nilogrin;
• Noblessite;
• Novigan;
• Novo Passit;
• Nurofen;
• Nurofen for children;
• Nurofen fort;
• Obsidan;
• Omaron;
• Optinat;
• Panadol;
• Paracetamol;
• Pentalgin;
• Pikamilon;
• Revalgine;
• Redergin;
• Remidon;
• Retafil;
• Rudotel;
• Sinkapton;
• Sinusan;
• Solpadein;
• Stugeron;
• Sumygamren;
• Topamax;
• Upsarin of the UPSA;
• Faspik;
• Febricet;
• Fezam;
• Flamax;
• Fluxcold;
• Cefexon;
• Cinnarizine;
• Efkamon.

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