Pyridoxine (vitamin B6) - instructions for use, analogs, testimonials and release forms (tablets of 2 mg and 10 mg, injections in ampoules for injection of 5% hydrochloride) of a drug for the treatment of hypovitaminosis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Pyridoxine (vitamin B6). There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of pyridoxine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of pyridoxine in the presence of existing structural analogues.Use for the treatment of hypovitaminosis (vitamin B6 deficiency) in adults, children, as well as during pregnancy and lactation.

Pyridoxine - vitamin B6. It plays an important role in the metabolism; is necessary for the normal functioning of the central and peripheral nervous system. In phosphorylated form, pyridoxine is a coenzyme of a large number of enzymes acting on a non-oxidative exchange of amino acids (including decarboxylation and transamination processes). Pyridoxine is involved in the metabolism of tryptophan, methionine, cysteine, glutamic and other amino acids. It plays an important role in the exchange of histamine. Pyridoxine promotes normalization of lipid metabolism.

Composition

Pyridoxine hydrochloride + excipients.

Pharmacokinetics

Metabolized in the liver with the formation of pharmacologically active metabolites (pyridoxal phosphate and pyridoxamine phosphate). Distribution is predominantly in the muscles, liver and CNS. Penetrates through the placenta and into the mother's milk. It is excreted by the kidneys (with intravenous injection with bile - 2%).

Indications

• treatment and prevention of clinical insufficiency of vitamin B6;
• peptic ulcer of the stomach and duodenum;
• hypochromic and microcytic anemia;
• Parkinsonism;
• chorea;
• toxicosis of pregnant women;
• hepatitis;
• dermatitis;
• exudative diathesis;
• neurodermatitis;
• psoriasis.

Forms of release

Tablets 2 mg and 10 mg.

Solution for injection 5% (injections in ampoules).

Instructions for use and dosing regimen

For treatment of vitamin B6 deficiency in adults - 80 mg 4 times a day. It is also possible intramuscular, subcutaneous or intravenous administration in a daily dose of 50-150 mg. The duration of treatment is determined by the type and severity of the disease.

To prevent the deficiency of vitamin B6 used in a dose of 40 mg per day.

Side effect

• allergic reactions;
• hypersecretion of hydrochloric acid.

Contraindications

• hypersensitivity to pyridoxine.

Application in pregnancy and lactation

It is possible to use pyridoxine during pregnancy and lactation (breastfeeding) according to the indications.

special instructions

With caution apply for peptic ulcer of the stomach and duodenum, IHD.

With severe liver damage, pyridoxine in high doses can cause deterioration of its function.

Drug Interactions

With simultaneous use with hormonal contraceptives, an increase in the concentration of pyridoxine in the blood plasma is possible.

With simultaneous use, the action of diuretics is potentiated.

When combined with levodopa, the effects of levodopa are reduced or completely inhibited.

With simultaneous use with isonicotinhydrazide, penicillamine, cycloserine, a decrease in the effectiveness of pyridoxine is possible.

With simultaneous use with phenytoin, phenobarbital, the concentrations in the blood plasma of phenytoin and Phenobarbital may decrease.

Analogues of the drug Pyridoxine (vitamin B6)

Structural analogs for the active substance:

• Pyridoxine bufus;
• Pyridoxine Vial;
• Pyridoxine hydrochloride.

Analogues for the pharmacological group (vitamins and vitamin-like drugs):

• D Panthenol;
• Alpha Tocopherol acetate Vitamin E;
• Aquadetry;
• Beta carotene;
• Vitamin A Retinol;
• Vitamin B12 Cyanocobalamin;
• Vitamin B1 Thiamine;
• Vitamin B2 Riboflavin;
• Vitamin D3 is a cholecalciferol;
• Vitrum;
• Herboton;
• Geriatrix;
• Dexpanthenol;
• Doppelgerc Vitamin E forte;
• Yeast beer;
• Calcium pantothenate;
• Calcium folinate;
• Carnitine;
• Cocarboxylase;
• Levocarnitine;
• Multi tabs;
• Multivita plus;
• Niacin;
• Nicotinamide;
• Panthenol;
• Prenatal;
• Fish fat;
• Sana'a Sol;
• Ferrinate;
• Folic acid;
• Cholecalciferol;
• Rosehip syrup;
• Eikonol;
• Ergocalciferol.

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