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Aquadetrim - instructions for use, reviews, analogs and formulations (aqueous solution) of medicines for the treatment of vitamin D3 deficiency, rickets and osteoporosis in adults, children (including infants and newborns) and during pregnancy. Composition

Aquadetrim - instructions for use, reviews, analogs and formulations (aqueous solution) of medicines for the treatment of vitamin D3 deficiency, rickets and osteoporosis in adults, children (including infants and newborns) and during pregnancy. Composition

In this article, you can read the instructions for using the drug Aquadetrim. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Vitamins Aquadetrim in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Aquadetrim in the presence of existing structural analogues.Use for the treatment of vitamin D3 deficiency, rickets and osteoporosis in adults, children (including infants and newborns), as well as during pregnancy and lactation. Composition of the preparation.

 

Aquadetrim - a drug that regulates the exchange of calcium and phosphorus. Vitamin D3 is an active antirachitic factor. The most important function of vitamin D is the regulation of calcium and phosphate metabolism, which contributes to the mineralization and growth of the skeleton.

 

Vitamin D3 is a natural form of vitamin D, which is formed by a person in the skin under the influence of sunlight. Compared with vitamin D2 is characterized by 25% higher activity.

 

Kolekaltsiferol plays an important role in the absorption of calcium and phosphate in the intestine, in the transport of mineral salts and in the process of calcification of bones, it also regulates the excretion of calcium and phosphate by the kidneys.

 

The presence of calcium ions in the blood in physiological concentrations ensures the maintenance of muscle tone of skeletal muscles, the function of the myocardium, facilitates the conduction of nervous excitement, regulates the process of blood coagulation.

 

Vitamin D is necessary for the normal functioning of the parathyroid glands, also participates in the functioning of the immune system, affecting the production of lymphokines.

 

Vitamin D deficiency in food, impaired absorption, calcium deficiency, as well as insufficient sun exposure during the child's rapid growth leads to rickets, in adults - to osteomalacia, pregnant women may experience tetany, a violation of the processes of calcification of newborn bones.

 

An increased demand for vitamin D occurs in women during menopause, as they often develop osteoporosis due to hormonal disorders.

 

Composition

 

Kolekaltsiferol (vitamin D3) + auxiliary substances.

 

Pharmacokinetics

 

Aquadetrim aqueous solution is absorbed better than the oil solution (this is important when used in premature infants, because in this category of patients there is a lack of production and the intake of bile in the intestines, which violates the absorption of vitamins in the form of oily solutions). After ingestion, colcalciferol is absorbed from the small intestine. Metabolised in the liver and kidneys. Penetrates through the placental barrier. Excreted in breast milk. Kolekaltsiferol cumulates in the body. It is excreted by the kidneys in a small amount, most of it is excreted with bile.

 

Indications

 

Prevention and treatment:

  • vitamin D deficiency;
  • rickets and rachitis-like diseases;
  • hypocalcemic tetany;
  • osteomalacia;
  • metabolic osteopathy (hypoparathyroidism and pseudohypoparathyroidism);
  • osteoporosis, incl. postmenopauznogo (as part of complex therapy).

 

Forms of release

 

Drops for oral administration 10 ml (aqueous solution).

 

Instructions for use and dosage

 

The dose is set individually, taking into account the amount of vitamin D that the patient receives as part of the diet and in the form of medications.

 

The drug is taken in 1 spoon of liquid (1 drop contains 500 IU of colcalciferol).

 

For the purpose of prevention of full-term newborns from 4 weeks of life to 2-3 years, with proper care and sufficient stay in the open air, the drug is prescribed in a dose of 500-1000 IU (1-2 drops) per day.

 

Preterm infants from 4 weeks of life, twins and children living in unfavorable conditions, appoint 1000-1500 IU (2-3 drops) per day.

 

In the summer, the dose can be reduced to 500 IU (1 drop) per day.

 

Pregnant daily appoint 500 IU (1 drop) per day during the entire pregnancy, or 1000 IU per day, starting from the 28th week of pregnancy.

 

In the postmenopausal period 500-1000 IU (1-2 drops) are prescribed per day.

 

In order to treat rickets, the drug is prescribed daily at a dose of 2000-5000 IU (4-10 drops) per day for 4-6 weeks, depending on the severity of rickets (1, 2 or 3) and the course of the disease.In this case, the patient's clinical condition and biochemical parameters (calcium, phosphorus, activity of the alkaline phosphatase in the blood and urine) should be monitored. The initial dose is 2000 IU per day for 3-5 days, then with good tolerability the dose is increased to an individual therapeutic dose (usually up to 3000 IU per day). A dose of 5000 IU per day is prescribed only with pronounced bone changes. If necessary, after 1 week break, the course of treatment can be repeated.

 

Treatment should continue until a clear therapeutic effect, followed by a transition to a prophylactic dose of 500-1500 IU per day.

 

In the treatment of rachitis-like diseases, 20,000-30,000 IU (40-60 drops) per day are prescribed depending on the age, body weight and severity of the diseases, under the control of biochemical blood indices and urinalysis. The course of treatment is 4-6 weeks.

 

In the treatment of postmenopausal osteoporosis (as part of complex therapy) 500-1000 IU (1-2 drops) are prescribed per day.

 

Side effect

  • loss of appetite;
  • nausea, vomiting;
  • head, muscle and joint pain;
  • constipation;
  • dryness in the oral cavity;
  • polyuria;
  • weakness;
  • violation of the psyche, incl. depression;
  • loss of body weight;
  • sleep disturbance;
  • temperature increase;
  • in the urine appears protein, white blood cells, hyaline cylinders;
  • increase in the level of calcium in the blood and its excretion in the urine;
  • it is possible calcification of kidneys, blood vessels, lungs;
  • hypersensitivity reactions.

 

Contraindications

  • hypervitaminosis D;
  • hypercalcemia;
  • hypercalciuria;
  • urolithiasis (formation of calcium oxalate stones in the kidneys);
  • sarcoidosis;
  • acute and chronic kidney disease;
  • kidney failure;
  • active form of pulmonary tuberculosis;
  • children up to 4 weeks;
  • increased sensitivity to vitamin D3 and other components of the drug (especially benzyl alcohol).

 

Application in pregnancy and lactation

 

In pregnancy, do not use Akvadetrim in high doses because of the possibility of teratogenic effects in case of an overdose.

 

With caution should be appointed Aquadetrim during lactation, tk. when using the drug in high doses in a nursing mother, it is possible to develop symptoms of an overdose in a child.

 

During pregnancy and during breastfeeding, the dose of vitamin D3 should not exceed 600 IU per day.

 

Use in children

 

Contraindicated in children under 4 weeks.

 

special instructions

 

When prescribing the drug, you must consider all possible sources of vitamin D.

 

The use of the drug for medical purposes in children should be carried out under careful medical supervision and adjust the dosage regimen during periodic examinations, especially in the first months of life.

 

Long-term use of Aquadetrim in high doses or use of the drug in shock doses can lead to chronic hypervitaminosis D3.

 

Do not simultaneously use Aquadetrim and calcium in high doses.

 

Control of laboratory indicators

 

When using the drug for therapeutic purposes, it is necessary to monitor the level of calcium in the blood and urine.

 

Drug Interactions

 

With the simultaneous use of Aquadetrim with antiepileptic drugs, rifampicin, colestyramine, the absorption of colcalciferol decreases.

 

With the simultaneous use of Aquadetrim and thiazide diuretics, the risk of hypercalcemia increases.

 

Simultaneous use of Aquadetrim with cardiac glycosides can enhance their toxic effect (the risk of heart rhythm disturbances increases).

 

Analogues of the medicinal product Aquadetrim

 

Structural analogs for the active substance:

  • Wigantol;
  • Videchol;
  • Videole solution in oil;
  • Vitamin D3;
  • Vitamin D3 100 SD / S dry;
  • Vitamin D3 Bon;
  • Vitamin D3 aqueous solution;
  • Cholecalciferol.

Similar medicines:

Other medicines:

Reviews (25):
Guests
Katerina
Vitamin is good and necessary. But be careful with dosages for children. The fact that the dream is broken is for sure. Babies sleep badly and restlessly. But not all of course, eat that sleep well. I even checked - we accept - we do not sleep well, we do not accept, everything is good and we sleep well))
When my daughter was 1.6 years old and we were prescribed a neurologist to take three drops, and a couple of days later my child became afraid of sex. It lasted all 5-10 minutes somewhere. The sight is appalling. We'll take it to lunch, and later, by the evening it began, twice this was and I immediately stopped giving D3.That's horrible! At first I was frightened that my child was going crazy slowly and with a psyche something. But thank God, everything is fine with us. I read the annotation and understood everything. Three drops were too much for her. Although before that we drank it almost always 1 drop and everything was fine. So, that's what we had. Little does anyone like this happen, so they know and do not get scared ...
Guests
Elena
We are now, in winter we take 2 drops of aquadetrim, and last summer in overcast weather the pediatrician recommended giving 1 drop. My son is healthy and I'm happy about it. I know about rickets only from articles on the Internet.
Guests
Julia
I like that aquadetrim is an effective drug and is easily digested. Just think, 1 drop of solution, and how much benefit from it to the baby. We were assigned in the winter to take akvadetrim for 1 drop. Vitaminized with pleasure, because they are also delicious)))
Guests
Olesya
Tell me, I'm breastfeeding a three-month-old baby, I take vitamins for nursing, in which D3 is already contained, will there be an overdose if I give 1 drop per day for prophylaxis?
Administrators
admin
OlesyaThe rule is universal. If you take one multivitamin, then combine it with other vitamins and vitamin complexes is not recommended.

The exception is the individual characteristics of the body and severe diseases, when there is still a deficit of certain vitamins, despite the intake of some multivitamins, but you yourself do not diagnose it and in such cases you need to go to the doctor.
Visitors
ira.s
Vitamin D in the blood I was much below the permissible limit, so I was appointed akvadetrim. Maybe I was too sensitive to the drug or the dose was shock (the first six weeks of 6 drops, followed by a decrease), only on the second day there was muscle pain. At first it was not very strong, but with every day it intensified. Wild pains under the knees, when I squat, dry mouth, bad sleep. After two months of admission, I could not normally go down or go up. If she stood for a long time, then she barely made the first steps. If you were sitting, you could hardly get up. It became hard to put on or undress - my forearms hurt terribly. It's hard to lie.When I lay on my side, my shoulder began to hurt. I had to roll all the night without sideways. Do it very slowly and keep your legs bent. For two months I lost 9 kilograms. The doctors in the polyclinic could say nothing. After two and a half months I stopped taking the drops myself. Slightly gained weight but the pain did not disappear. I have not accepted them for three months, but there is no improvement. I continue to lose weight, but not so quickly. Pain in forearms slowly increases. I can not straighten my arms out to the sides, get them behind my back, lift them up. When you touch the muscles, you do not feel the pain. When you stand or walk, there is no pain. You lie - your hands hurt. In the morning you wake up from severe pain in your forearms. Has handed over the analysis of daily loss of a calcium with urine. I have 11 mmol per day. Vitamin D - 37.99 ng / ml. A doctor in an osteoporotic center thinks that aquadetry can not give such a side effect, although the instructions say this. He does not even want to listen. He says that I understand the clinic with the therapist, what's the matter. What am I supposed to do? Now I will retake the analysis of the daily loss of calcium in the urine, donate blood and densitometry.
Administrators
admin
ira.sIf joints hurt, then it is better not to try for the hundredth time to reassess the analysis for vitamin D3, and make an x-ray of the joints that hurt. It is possible that the doctor is right and your pains are not caused by taking Aquadetrim, but appeared by themselves (although taking the drug and provoking the development of these processes as a stress factor). Sometimes it happens when you start taking one drug, but it's a completely different sore. Especially since, as I understand it, you do not take any vitamin preparations at all for two weeks, and during this time any negative action of the medicine should have ended. In general, start looking for your problems with the radiography of the joints that hurt, as well as with the biochemical blood test with the definition of joint parameters (CRP, rheumatifactor and other indicators).
Guests
Anna Eva
She fed the child to three years of age with aquadritim. We have very little sun, and these droplets only went for good. I myself take them in the spring.
Visitors
ira.s
Joints just do not hurt me. The muscles ache.The therapist says that there may be an overabundance of calcium in the muscles. I prescribed medicine. And contraindications in the instructions for the medicine for whom they write?
Administrators
admin
ira.s, I can say one thing. Your troubles can and triggered the drug Aquadetrim, but now the cause is definitely not in excess of vitamin D3. Especially according to the results of the tests (depends on the laboratory), but if you take the average data, the level of vitamin you had at the time of delivery was at the lower limit of the norm, which is an overabundance. So look for the cause of your problems with your doctor and start by putting trivial tests (blood, urine, biochemistry, sugar, ECG, ultrasound of internal organs). The simplest screening sometimes gives many reasons and points of application for a specialist.
Guests
Tatyana
We have been drinking aquadritem for 3 years, started at 2 months. The child is healthy, there are no signs of rickets. A good and useful vitamin for children.
Only you have to be more careful with the dosage. A couple of times it turned out that I gave more drops than necessary. Then the following days did not give aquadetry at all.
Guests
Violetta
I give half a year aquadetry to my baby. At us under analyzes a lack of vitamin D. Therefore initially to us have registered to accept on three drops. Now, after a second analysis, everything has improved, we have replenished the reserves in the body and now only for the sake of prevention drink on a drop. Already 4 teeth in our country and fontanel grow in time
Guests
Svetlana K
Has handed over the analysis on vitamin D the general or common. The result is 10.56 ng / ml (at a rate of 30-100). The doctor appointed aquadetrim 10 mg 1 bottle once a month in one session. And so three months, then retake the analysis. I doubt the dosage, because in the instructions and in the reviews write 1-3 drops every day. What to do?
Administrators
admin
Svetlana K, Lack of vitamin D3 according to the analysis takes place to be. There should not be any special dosages for these vitamin values, and it's quite enough for the average therapeutic dosages, you can slightly more (up to 6 drops of the drug). One bottle of Aquadetrim contains 300 drops, which is 70-100 diurnal doses of vitamin D3. In my opinion or the doctor something is confused, or the appointment is doubtful.
Guests
Gulya
To me the doctor the gynecologist has appointed or nominated Akvadetrim on 10 drops every day in the morning. After that, nausea is no appetite, no strength, dizziness.
Guests
Sofa
And I thought I had one such. My legs hurt - I can not sleep. Near the knees, under the knees. I take aquadetrim for 1,5 months 10 drops a day. The doctor appointed or nominated: a lack of a calcium and vitamin D. It has begun it akkurat after the beginning of reception. And the sleep had sharply worsened.
Guests
Irina
Akvadetrim I give the child six months. We are only 7 months old and already have 4 teeth. I give a drop every morning. In the summer they did not take a break, the pediatrician said that the child now has active growth, vitamin D should be given on cloudy days and when there is not much sun in the sun. We grow and develop well. At 6 months, the analysis for vitamin D was given, it is normal for us.
Guests
TATYANA
Good afternoon. To me the doctor the endocrinologist too has appointed or nominated akvadetrim 1/2 a vial or flask in the morning 1 time a week. Very dubious dosage. 13.5 ng / ml at the rate of 60. I am 33 years old.
Administrators
admin
TATYANA, Superfluous water-soluble vitamins and trace elements in the human body are utilized and do not bring benefits. Only fat-soluble vitamins are accumulated, therefore, when administered in large quantities, an overdose is possible. I also think that the method of using Aquadetrim is more doubtful than that prescribed in the instructions.
Guests
a guest
I accept aquadetry for about half a month. I started to gain weight, although I eat the same way. Has typed already 4 kg.
Guests
LOVE.
At me an osteopenia (researches have shown on vit. D 31,89, a calcium общ.2,50, calcium ionized 1,28). The endocrinologist appointed Aquadetrim for 50 caps. 2 times a week, 4 weeks. Is the dosage too high? I'm afraid to accept. I am 65 years old. Waiting for your reply.
Administrators
admin
LOVE.If every day there are such high doses, it would be a lot. And so it is normal, given that you have a curative course of Aquadetrim, and not preventive.
Guests
Galina
Hello.After reading the previous reviews, I think my dosage is incorrect, vit. D is 2 times lower. assigned 50 cap. in the morning and 50 cap. at lunch. Is it dangerous?
Administrators
admin
Galina, 100 drops per day is a lot. Definitely smells like an overdose. There are bolus preparations on the market that need to be taken once a week and therefore contain high dosages of vitamin D (the same as Devit), but Aquadetrim does not apply to such drugs. It is taken regularly and gradually, according to instructions.
Guests
Anastasia I.
I go to the gym. Between the girls and the trainer there was talk about the need for vitamin D. Some of them took multivitamins, where the composition already had a vitamin. The trainer strongly recommended starting to drink vitamin D additionally to strengthen the bone system, improve the condition of the muscles and metabolism. Yes, he also positively influences the mood. And the dosage of the element in multivitamins is less than necessary. Well at least in the summer, the sun is spoiling us, and even on the street you are longer.But most of the time of the year does not satisfy our need for this vitamin. Yes, and in the daytime we are mostly at work, indoors. Whence at us then forces, a tonus?
Many of the girls started taking Aquadetrim. Strength and vivacity increased. And honestly, the results of training improved, a couple more smudges from the thighs removed.

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