Tobrex - instructions for use, reviews, analogs and forms of release (eye drops 0,3%, ointment for eyes 0,3%) drugs for the treatment of conjunctivitis and blepharitis in adults, children (including babies and newborns) and during pregnancy
In this article, you can read the instructions for using the drug Tobrex. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Tobrex in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tobrex in the presence of existing structural analogs. Use for the treatment of conjunctivitis, blepharitis and keratitis in adults, children (including infants and newborns), as well as during pregnancy and lactation.
Tobrex - a broad-spectrum antibiotic from the aminoglycoside group. At low concentrations, it acts bacteriostatically (blocks the 30S subunit of the ribosome and breaks down the protein synthesis), and at higher bactericidal levels (it breaks the function of cytoplasmic membranes, causing death of the microbial cell).
Highly active against Staphylococcus spp. (including coagulase-negative and coagulase-positive, as well as strains resistant to penicillin); Streptococcus spp. (including alpha-beta-hemolytic species, some non-hemolytic species, Streptococcus pneumoniae); Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis (indole-negative) and indole-positive species of Proteus spp., Haemophilus influenzae, Haemophilus aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus (Herellea vaginacola), some species of Neisseria spp. (including Neisseria gonorrhoeae).
Composition
Tobramycin + excipients.
Pharmacokinetics
With topical application, systemic absorption is low.
Indications
- blepharitis;
- conjunctivitis;
- keratoconjunctivitis;
- blepharoconjunctivitis;
- keratitis;
- iridocyclitis;
- prevention of postoperative complications in ophthalmology.
Forms of release
Eye drops 0,3%.
Ointment for eyes 0,3%.
Instructions for use and how to use them
With a mild infectious process, the drug is instilled in 1-2 drops in the conjunctival sac of the affected eye (or eyes) every 4 hours.
In the case of acute acute infection, the drug is instilled every 30-60 minutes, as the inflammation decreases, the frequency of instillation of the drug is reduced.
Side effect
- itching;
- swelling of the eyelids;
- congestion hyperemia.
Contraindications
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
There is no sufficient experience in the use of the drug during pregnancy and lactation (breastfeeding). The use of eye drops Tobrex in pregnant women and nursing mothers is possible when the expected therapeutic effect exceeds the potential risk of side effects.
Use in children
There is no sufficient experience in the use of eye drops Tobrex in children (including infants and newborns). Possible use of the drug in children, if the expected therapeutic effect exceeds the potential risk of side effects.
special instructions
Prolonged use of eye drops Tobrex, as in the case of using other antibiotics, can lead to increased growth of non-susceptible microorganisms (including fungi).It is recommended to sow before and after the end of treatment if the clinical result is unsatisfactory.
It is unacceptable to wear contact lenses during treatment with the drug.
Impact on the ability to drive vehicles and manage mechanisms
Patients who, after Tobrex instillation, have a visual impairment temporarily impaired, it is not recommended to drive a car or work with complicated equipment, machines or some other complicated equipment that requires clarity of vision.
Drug Interactions
In the case of simultaneous administration of eye drops Tobrex with systemic antibiotics from the aminoglycoside group, it is possible to intensify systemic side effects (nephrotoxic, ototoxic effect, disturbance of mineral metabolism and hemopoiesis).
Analogues of drug Tobrex
Structural analogs for the active substance:
- Bramitob;
- Brulamycin;
- Dilaterol;
- Nebzin;
- Toby;
- Toby Podhaler;
- Tobramycin Gobbi;
- Teborocin ADS;
- Тобрекс 2Х;
- Tobrup.
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