Postinor - instructions for use, reviews, analogs and forms of release (tablets 0.75 mg) drugs for emergency contraception. Menstruation, pain and possible pregnancy after taking the contraceptive
In this article, you can read the instructions for using the drug Postinor. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Postinor in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Postinor analogs in the presence of existing structural analogues. Use for emergency contraception. Menstruation, pain and possible pregnancy after taking the contraceptive.The effect of alcohol on the availability of the drug.
Postinor - a synthetic preparation with a contraceptive effect, expressed by gestagenic and antiestrogenic properties. With the recommended dosage regimen, the active substance of the drug levonorgestrel suppresses ovulation and fertilization if sexual contact occurs in the pre-evolution phase, when the possibility of fertilization is greatest. It can also cause changes in the endometrium, which prevent implantation. The drug is not effective if the implantation has already occurred.
Efficacy: with the help of Postinor tablets, pregnancy can be prevented in about 85% of cases. The more time passed between sexual intercourse and drug intake, the lower its effectiveness (95% during the first 24 hours, 85% from 24 to 48 hours and 58% from 48 to 72 hours). Thus, the reception of the Postinor tablets is recommended to begin as soon as possible (but no later than 72 hours) after sexual contact, if no protective measures have been applied. In the recommended dose, levonorgestrel does not significantly affect the factors of blood coagulability, the exchange of fats and carbohydrates.
Pharmacokinetics
With oral administration of Postinor, the drug is quickly and almost completely absorbed.Absolute bioavailability is almost 100% of the dose. Levonorgestrel is excreted approximately equally by the kidneys and through the intestine exclusively in the form of metabolites. Biotransformation of levonorgestrel corresponds to the metabolism of steroids.
Indications
- emergency (postcoital) contraception (after unprotected sex or unreliability of the contraceptive method used).
Forms of release
Tablets 0.75 mg.
Instructions for use and how to use them
The drug is taken orally. It is necessary to take 2 tablets in the first 72 hours after unprotected intercourse. The second tablet should be taken 12 hours later (but not later than 16 hours) after taking the first tablet.
To achieve a more reliable effect, both tablets should be taken as soon as possible after unprotected intercourse (no later than 72 hours).
If vomiting occurs within 3 hours after the 1st or 2nd dose of Postinor Tablets, one more Postinor tablet should be taken.
Postinor can be used at any time of the menstrual cycle. In the case of an irregular menstrual cycle, you must first exclude pregnancy.
After taking an emergency contraceptive before the next menstrual period, local barrier contraceptive methods should be used (for example, a condom, a cervical cap). The use of the drug with repeated unprotected intercourse during one menstrual cycle is not recommended because of the increased frequency of acyclic bleeding / bleeding.
Side effect
- urticaria, rash, itching, swelling of the face;
- vomiting, diarrhea;
- dizziness, headache;
- soreness in the chest;
- delay in menstruation (no more than 5-7 days; if menstruation is delayed for a longer period, pregnancy should be excluded);
- nausea;
- fatigue;
- pain in the lower abdomen;
- acyclic bleeding (bleeding).
Contraindications
- adolescence up to 16 years;
- severe hepatic impairment;
- pregnancy;
- rare hereditary diseases, such as lactose intolerance, lactase deficiency or glucose-galactose malabsorption;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
Postinor is contraindicated in pregnancy.If the pregnancy occurred when using an emergency method of contraception, then based on the available data, the adverse effect of the drug on the fetus is not revealed.
Levonorgestrel is excreted in breast milk. After taking the drug, breastfeeding should be stopped for 24 hours.
special instructions
Postinor should be used exclusively for emergency contraception. Repeated use of the drug Postinor during one menstrual cycle is not recommended.
Efficacy of tablets Postinor after unprotected intercourse, which did not use contraceptives, with time decreases.
The drug does not replace the use of permanent methods of contraception. In most cases, Postinor does not affect the nature of the menstrual cycle. However, acyclic bleeding may occur and menstruation may be delayed for several days. If you delay menstruation for more than 5-7 days and change its nature (meager or abundant discharge), you must exclude pregnancy. The appearance of pain in the lower abdomen, fainting can indicate ectopic (ectopic) pregnancy.
To adolescents under 16 years in exceptional cases (incl.when raping) it is necessary to consult a gynecologist for confirmation of pregnancy.
After emergency contraception, a gynecologist's consultation is recommended to select the most acceptable method of permanent contraception.
Emergency contraception does not protect against sexually transmitted diseases.
For violations of the function of the gastrointestinal tract (for example, with Crohn's disease), a decrease in the effectiveness of the drug is possible.
Simultaneous reception of the drug Postinor and alcohol increases the risk of bleeding and increases the load on the liver (hepatotoxicity).
Impact on the ability to drive vehicles and manage mechanisms
The influence of Postinor on the ability to drive vehicles and mechanisms is not investigated.
Drug Interactions
The following drugs may decrease the effectiveness of levonorgestrel: amprekavil, lansoprazole, nevirapine, oxcarbazepine, tacrolimus, topiramate, tretinoin, barbiturates including primidone, phenytoin and carbamazepine, preparations containing St. John's wort (Hypericum perforatum), rifampicin, ritonavir, ampicillin, tetracycline, rifabutin, griseofulvin.Levonorgestrel reduces the effectiveness of hypoglycemic and anticoagulant (coumarin derivatives, phenyldione) drugs. Increases plasma concentrations of GCS. Women who take these drugs should consult a doctor.
Preparations containing levonorgestrel may increase the risk of toxicity of cyclosporine due to the suppression of its metabolism.
Analogues of the drug Postinor
Structural analogs for the active substance:
- Levonorgestrel;
- Microlus;
- Mirena;
- Norplant;
- Escapel;
- Eskinor-F.
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