Imodium - instructions for use, reviews, analogs and forms of release (capsules and tablets for resorption of 2 mg, chewing Plus) of a medicament for the treatment of diarrhea in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Imodium. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Imodium in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Imodium with available structural analogues. Use to treat diarrhea in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Imodium - antidiarrhoeal preparation.

Loperamide (the active substance of Imodium) binds to opioid receptors in the intestinal wall, which leads to inhibition of propulsive peristalsis, increased resorption of water and electrolytes. Loperamide does not change the physiological microflora of the intestine and increases the tone of the anal sphincter.

Simethicone is an inert surface-active compound. Has a defoaming effect, and therefore facilitates the symptoms associated with diarrhea (flatulence, abdominal discomfort, spastic pain).

Imodium does not have a central effect.

Composition

Loperamide hydrochloride + excipients.

Loperamide hydrochloride + Simethicone + auxiliary substances (Imodium plus).

Pharmacokinetics

Loperamide is well absorbed from the intestine. Simethicone is not absorbed from the digestive tract. Loperamide is subjected to the effect of "first passage", while almost completely metabolized in the liver and excreted with bile in the form of conjugated metabolites. Due to the intensive metabolism, the concentration in the blood plasma of the unchanged loperamide is very low. Metabolites of loperamide are excreted with feces.

Indications

• acute and chronic diarrhea;
• for the purpose of stool regulation in patients with ileostomy;
• diarrhea of ​​any etiology and accompanying symptoms (flatulence, abdominal discomfort, spastic pain).

Forms of release

Tablets for resorption of 2 mg.

Capsules 2 mg.

Chewable tablets (Imodium plus).

Instructions for use and reception scheme

The drug is prescribed inside.

In acute diarrhea, adults and elderly patients are given an initial dose of 4 mg, then 2 mg after each defecation in the case of a loose stool. Children older than 6 years are prescribed in an initial dose of 2 mg, then - 2 mg after each act of defecation in the case of a loose stool.

In chronic diarrhea, adults and elderly patients are given an initial dose of 4 mg per day. Then the dose is adjusted so that the stool frequency is 1-2 times a day, which is usually achieved with a maintenance dose of 2-12 mg per day. Children older than 6 years are prescribed in an initial dose of 2 mg per day. Then the dose is adjusted so that the stool frequency is 1-2 times a day, which is usually achieved with a maintenance dose of 2-12 mg per day.

The maximum daily dose for acute and chronic diarrhea in adults is 16 mg; in children - 6 mg per 20 kg body weight - up to 16 mg.

When a normal chair appears or if there is no stool for more than 12 hours, the drug is canceled.

The tablet for resorption should be put on the tongue. Within a few seconds, it dissolves on the surface of the tongue and it can be swallowed with saliva without water.

Imodium Plus (chewing tablets)

The drug is prescribed for adults and children over 12 years in the initial dose of 2 tablets, then - 1 tablet after each liquid stool. The maximum daily dose is 4 tablets. Duration of reception - no more than 2 days.

When using the drug in elderly patients, dose adjustment is not required.

When using the drug in patients with impaired renal function, a dose reduction is not required.

Side effect

• constipation and / or bloating;
• intestinal colic;
• pain or discomfort in the abdomen;
• nausea, vomiting;
• dry mouth;
• intestinal obstruction;
• fatigue;
• drowsiness;
• dizziness;
• skin rash;
• a feeling of burning or tingling of the tongue, which occurs immediately after taking the drug in the form of tablets for resorption;
• retention of urine.

Contraindications

• acute dysentery and other infections of the gastrointestinal tract (caused, including Salmonella spp., Shigella spp., Campylobacter spp.);
• intestinal obstruction (including if necessary to avoid suppression of peristalsis);
• diverticulosis;
• acute ulcerative colitis;
• pseudomembranous enterocolitis (diarrhea caused by taking antibiotics);
• 1 trimester of pregnancy;
• lactation period (breastfeeding);
• children under 6 years of age (imodium plus up to 12 years);
• hypersensitivity to loperamide and / or other components of the drug.

Application in pregnancy and lactation

Imodium is contraindicated in the first trimester of pregnancy.

Although there is no indication of a teratogenic or embryotoxic effect, Imodium may be prescribed in the second and third trimesters of pregnancy only in cases where the intended benefit of therapy for the mother exceeds the potential risk to the fetus.

Loperamide in small amounts excreted in breast milk, so if you need to use the drug during lactation, breastfeeding should be discontinued.

special instructions

The drug should be stopped immediately if constipation or bloating develops.

Since the treatment of diarrhea by Imodium is only symptomatic, along with this it is necessary, if possible, to use etiotropic drugs.

In diarrhea, especially in children, hypovolemia and a decrease in the electrolyte content may occur.In such cases, the most important is replacement therapy to replenish fluid and electrolytes.

In acute diarrhea, if there is no clinical improvement within 48 hours, Imodium intake should be discontinued and the infectious genesis of diarrhea should be excluded.

Do not use for diarrhea with an admixture of blood in the stool and high fever.

Patients with AIDS should immediately stop treatment at the first sign of bloating. In some cases, in patients with AIDS with infectious colitis, both viral and bacterial in the treatment with Imodium, toxic expansion of the large intestine may develop.

Patients with a dysfunction of the liver should be carefully monitored for the purpose of timely detection of signs of toxic damage.

During the treatment period, it is recommended that the diet be followed and the fluid replenished.

It should be borne in mind that the tablets for resorption are quite fragile, so to avoid damage they can not be pushed through the foil. In order to get a tablet from the blister, it is necessary to take the foil by the edge, completely remove it from the hole in which the tablet is located, and gently pushing from below, to remove the tablet from the package.

Impact on the ability to drive vehicles and manage mechanisms

During the period of treatment, it is necessary to refrain from driving and practicing potentially dangerous activities that require high concentration of attention and high speed of psychomotor reactions.

Drug Interactions

With the exception of drugs that have a similar pharmacological effect, due to the mutual enhancement of effects, interaction with other drugs has not been established.

Analogues of the medicinal preparation Imodium

Structural analogs for the active substance:

• Vero Loperamide;
• Diar;
• Diarol;
• Laremide;
• Lediumum;
• Loperacap;
• Loperamide;
• Superylope;
• Enterobene.

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