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Erius - instructions for use, reviews, analogs and forms of release (syrup or drops, 5 mg tablets and 2.5 mg for resorption) drugs for the treatment of urticaria and allergic rhinitis in adults, children and pregnancy. Composition

Erius - instructions for use, reviews, analogs and forms of release (syrup or drops, 5 mg tablets and 2.5 mg for resorption) drugs for the treatment of urticaria and allergic rhinitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Erius. Presented are reviews of visitors to the site - consumers of this medication, as well as the opinions of physicians specialists on the use of Erius in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Erius in the presence of existing structural analogs. Use for the treatment of urticaria and allergic rhinitis in adults, children, as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.

 

Erius - antihistamine long-acting drug, blocker of peripheral histamine H1-receptors. Desloratadine is the primary active metabolite of loratadine. Inhibits a cascade of reactions of allergic inflammation, incl. release of pro-inflammatory cytokines including the interleukins IL-4, IL-6, IL-8, IL-13, the release of proinflammatory chemokines, production of superoxide anion by activated polymorphonuclear neutrophils adhesion and chemotaxis eosinophils selection adhesion molecules such as P-selectin, IgE - mediated release of histamine, prostaglandin D2 and leukotriene C4. Thus, it prevents the development and facilitates the allergic reactions has antipruritic and antiexudative action, reduces capillary permeability, prevents the development of edema, smooth muscle spasm.

 

The drug has no effect on the central nervous system, has almost no sedative effect (does not cause drowsiness) and does not affect the rate of psychomotor reactions.

 

Does not cause an extension of the QT interval on the ECG.

 

The action of Erius begins within 30 minutes after ingestion and lasts for 24 hours.

 

Composition

 

Desloratadine + auxiliary substances.

 

Pharmacokinetics

 

After taking the drug inside, Erius is well absorbed from the digestive tract. Simultaneous food intake or the simultaneous use of grapefruit juice does not affect the distribution of desloratadine. Does not penetrate the blood-brain barrier (BBB). Desloratadine is excreted from the body in the form of a glucuronide compound and in a small amount (less than 2% with urine and less than 7% with feces) unchanged.

 

Indications

  • allergic rhinitis (elimination or relief of sneezing, nasal congestion, mucus discharge from the nose, itching of the nose, itching of the palate, itching and redness of the eyes, lachrymation);
  • urticaria (reduction or elimination of itching, rash).

 

Forms of release

 

The tablets covered with a cover of 5 mg.

 

Tablets for resorption of 2.5 mg and 5 mg.

 

Syrup (the ideal children's form of the drug).

 

Other forms, be it drops, spray or ointment, at the time of publication in the directory did not exist.

 

Instructions for use and dosage

 

Pills

 

Adults and adolescents aged 12 years and over are prescribed 5 mg once a day, regardless of food intake, preferably at the same time of day.

 

The tablet should be swallowed whole, not liquid, squeezed with a small amount of water.

 

Syrup

 

Children aged 1 to 5 years are prescribed 1.25 mg (2.5 ml syrup) once a day; children aged 6 to 11 years - 2.5 mg (5 ml syrup) 1 time per day; adults and teenagers over 12 years - 5 mg (10 ml of syrup) 1 time per day.

 

Syrup is taken orally, regardless of food intake, with a small amount of water.

 

Side effect

  • fatigue;
  • dry mouth;
  • headache;
  • dizziness;
  • tachycardia;
  • palpitation;
  • anaphylaxis;
  • angioedema;
  • itching;
  • hives;
  • rash;
  • nausea, vomiting;
  • diarrhea;
  • increased body temperature;
  • insomnia.

 

Contraindications

  • pregnancy;
  • lactation (breastfeeding);
  • age up to 1 year (for syrup);
  • age up to 12 years (for coated tablets);
  • hereditarily transmitted diseases (fructose intolerance, impaired glucose / galactose absorption or sugarase / isomaltase insufficiency in the body) due to the presence of sucrose and sorbitol in the syrup;
  • hypersensitivity to the components of the drug.

 

Application in pregnancy and lactation

 

The use of the drug in pregnancy is not recommended due to the lack of clinical data on the safety of its use in this period.

 

Desloratadine is excreted in breast milk, so the use of Erius during breastfeeding is not recommended.

 

special instructions

 

The effectiveness and safety of Erius application in the form of syrup in children under the age of 1 year is not established.

 

In most cases, rhinitis in children under 2 years of age is of an infectious nature. There were no studies of the efficacy of Erius in rhinitis of infectious etiology.

 

Differential diagnosis between allergic rhinitis and rhinitis of a different origin in children under 2 years of age presents certain difficulties. When making a differential diagnosis, attention should be paid to the presence or absence of foci of infection or structural anomalies of the upper respiratory tract, to conduct a careful history, examination, as well as appropriate laboratory tests and skin tests.

 

Eating does not affect the effectiveness of the drug.

 

Influence on the ability to drive and drive machinery

 

In the recommended dose, Erius does not affect the ability to drive vehicles or control mechanisms.

 

Drug Interactions

 

Erius does not increase the effects of ethanol (alcohol) on the central nervous system.

 

Clinically significant interaction with other drugs has not been identified.

 

Analogues of the drug Erius

 

Structural analogs for the active substance:

  • Desloratadine;
  • Desloratadine Teva;
  • Desloratadine hemisulphate;
  • Lordestin.

Similar medicines:

Other medicines:
Reviews (7):
Guests
Lyudmila Leonidova
My child was not sick for almost a year and a half. And when the first time we seriously caught a cold, the pediatrician, in addition to the basic drugs, Erius appointed us. I bought something, but after reading the instructions, I decided not to give it. Sopley in the child was not, only the temperature and cough. So the bank of syrup stood unclaimed. And the husband suffers from an allergy to some pollen, because from mid-July to September, his nose, sneezing and red eyes are constantly stuffed. Remembering about the drug Erius, who is standing around, I suggest that his wife try it, although he was already desperate, so many tried products did not give a result. But what was our surprise when the very next day the husband's condition improved significantly, from the unpleasant symptoms of allergy, there was almost no trace left. And he was saved.Pleasure is, it should be noted, not cheap, but no money is not a pity, just to feel normal.
Guests
Alexey
Thank you very much for this site - it is true clearly and without superfluous hypothetical hypotheses! You Well done - Thank you very much !!!
Guests
people
To the son 4 years 2 from them we accept erius. Helps directly say good (tried many drugs) the only thing that confuses. How long it is possible to drink it from the doctor of the allergist did not recognize.
Administrators
admin
people, The preparation of Erius can be taken for a long time, but sometime it will be necessary to try to cancel it, and it is better to do this after examining your child and consulting an allergist, because you may be shown a step-by-step withdrawal of therapy, there are many nuances that need to be learned from the treating doctor. Therefore, consult a specialist internally, it may be time for your child's body to cope with allergens independently.
Guests
Margo27
We with the husband for 50. Last 8 years I had an allergy on heat and the sun in the form of a urticaria on a body and blisters or blebs on the face. Then the bubbles burst, fluid leaked, the skin covered with red mounds. For seven days I did not go out on the street because I was like a "Kruger". But 2-3 years ago, the pharmacy offered an erius, which made life easier for me, although it did not heal completely. A year ago I was treated in China and forgot about allergies! My husband learned two years ago what an allergy to cold is in the form of rhinitis, lacrimation, headache, weakness, even from a slight breeze of the wind. Erius consulted until recently. Treatment in China also did not help. What to do? Do not convey the words of his torment ...
Visitors
m2714175
Just do not think that I'm joking. After frequent visits to the sea (2-3 times a year) eight years ago, I started allergic to heat and sun. My face was reminiscent of Gogol's wiya, which did not make me abandon the South. Especially since Erius, who was an indispensable friend for the last 2-3 years, almost helped me at least not to hide from people. A year ago, after treatment (miraculously) in China, I forgot about the allergy.BUT ... Three years ago my husband had an allergy to cold. Even if he moves from room to room with a temperature difference of 3-5 degrees, he starts sneezing without a break, then he pours a stream from his nose, then his eyes water, and then his nose becomes like a purple shnobel and he can not breathe through it. Until recently, Erius helped him a lot. And treatment in China did not bring the desired effect. What to do? We are both active, sport with us. The difference between us is only that he has asthmatics in his family and before going to bed he loves to miss a glass of wine or two. And for me, alcohol is not tasty. Now I think, which of the two reasons prevents my husband from living. Can something advise?
Administrators
admin
Margo27Probably, it is necessary to address to the allergist, to hand over analyzes and assays, including cold. Probably, in addition consultation and the immunologist in especially started cases is required.

m2714175Probably, this you described the situation under the nickname Margo27 earlier. I can add only that the presence in the relatives of asthmatics already indicates possible allergic problems, so it will be necessary to be examined.And with alcohol for allergies it is necessary to tie, as it can have liver problems, and allergists (sensible) liver are checked without fail and many allergic problems are solved by the normalization of liver function.

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