Kombilipen - instructions for use, reviews, analogs and forms of release (tablets tablets, injections in ampoules) for the treatment of neuritis and neuralgia in adults, children and pregnancy. Composition
In this article, you can read the instructions for using the drug Koblipen. There are reviews of visitors to the site - consumers of this medication, as well as opinions of physicians specialists on the use of Kombilipen in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Kombilipen in the presence of existing structural analogs. Use for the treatment of neuritis and neuralgia in adults, children, as well as during pregnancy and lactation. Composition of the preparation.
Koblipen - combined multivitamin preparation. The effect of the drug is determined by the properties of the Vitamins that make up its composition.
Thiamine hydrochloride (vitamin B1) is involved in conducting a nerve impulse.
Benfotiamin - fat-soluble form of thiamine (vitamin B1), is involved in the conduct of a nerve impulse.
Pyridoxine hydrochloride (vitamin B6) has a vital effect on the exchange of proteins, carbohydrates and fats, is necessary for normal hematopoiesis, the functioning of the central nervous system and the peripheral nervous system. It provides synaptic transmission, inhibition processes in the central nervous system, participates in the transport of sphingosine, which is part of the nerve shell, is involved in the synthesis of catecholamines.
Cyanocobalamin (vitamin B12) is involved in the synthesis of nucleotides, is an important factor in normal growth, hematopoiesis and the development of epithelial cells; is necessary for the metabolism of folic acid and myelin synthesis.
Composition
Thiamine hydrochloride (Vit. B1) + Pyridoxine hydrochloride (Vit. B6) + Cyanocobalamin (Vit. B12) + Lidocaine hydrochloride + adjuvants (injection).
Benzothiamine + Pyridoxine hydrochloride (Vit B6) + Cyanocobalamin (Vit B12) + excipients (Tablets tablets).
Indications
In the complex therapy of the following neurological diseases:
- neuralgia of the trigeminal nerve;
- neuritis of the facial nerve;
- pain syndrome caused by diseases of the spine (intercostal neuralgia, lumboschialgia, lumbar syndrome, cervical syndrome, cervico-brachial syndrome, radicular syndrome caused by degenerative changes of the spine);
- polyneuropathy of various etiologies (diabetic, alcoholic).
Forms of release
Solution for intramuscular injection (injections in ampoules for injection).
Tablets coated with Koblipen tabs.
Instructions for use and reception scheme
Ampoules
The drug is administered intramuscularly.
With severe symptoms of the disease appoint 2 ml daily for 5-7 days, then 2 ml 2-3 times a week for 2 weeks; in mild cases - 2 ml 2-3 times a week 7-10 days.
Duration is determined by the doctor individually depending on the severity of the symptoms of the disease, but should not exceed 2 weeks.
For maintenance therapy it is recommended to take oral forms of B vitamins.
Pills
The drug should be taken after eating, without chewing and washing down with a small amount of liquid.
Adults appoint 1 tablet 1-3 times a day.
The duration of the course is according to the doctor's recommendation. It is not recommended to use the drug in high doses for more than 4 weeks.
Side effect
- itching;
- hives;
- labored breathing;
- angioedema;
- anaphylactic shock;
- increased sweating;
- tachycardia;
- acne.
Contraindications
- severe and acute forms of decompensated heart failure;
- pregnancy;
- lactation period (breastfeeding);
- childhood;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
The drug is contraindicated for use in pregnancy and lactation (breastfeeding).
Use in children
Kombilipen contains benzyl alcohol. Do not administer to children due to benzyl alcohol content in the preparation.
special instructions
When taking the drug is not recommended taking multivitamin complexes containing vitamins of group B.
Drug Interactions
Thiamin completely dissolves in solutions containing sulfites.
Thiamin is incompatible with oxidizing and reducing substances: mercuric chloride, iodide, carbonate, acetate, tannic acid, iron-ammonium citrate, as well as sodium phenobarbital, riboflavin, benzylpenicillin, Dextrose and metabisulphite.
Copper accelerates the destruction of thiamine; In addition, thiamine loses its effect with increasing pH (more than 3).
Levodopa reduces the effect of therapeutic doses of vitamin B6.
Vitamin B12 is incompatible with salts of heavy metals.
Ethanol (alcohol) dramatically reduces the absorption of thiamine.
Analogues of the drug Komlipen
Structural analogs for the active substance (multivitamin preparations):
- Alvitil;
- Angiovitis;
- Antioxidants;
- Aerovit;
- Beviplex;
- Benfolipen;
- Vectrum junior;
- Vetoron;
- Vibovit;
- Vitabeks;
- Vitamult;
- Vitatcitrol;
- Vitasharm;
- Hexavit;
- Gendevit;
- Heptavit;
- Decamewith;
- Jungle;
- Baby Jungle;
- Calcevit;
- Complymgam;
- Macrovitis;
- Milgamma;
- Multi-tabs;
- Multivita plus;
- Neurogamma;
- Neuromultivitis;
- Neurotrate forte;
- Pentovit;
- Pikovitz;
- Pikovitz Fort;
- Polybion;
- Watering Baby;
- Polivit for children;
- Multivitamin mixture;
- Pregnavit F;
- Revit;
- Ricavit;
- Sana'a-Sol;
- Stress formula 600;
- Stresstabs 500;
- Tetravit;
- Trigamma;
- Triovit Cardio;
- Undevit;
- Foliber;
- Unigamma.
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