Tavegil - instructions for use, reviews, analogs and forms of release (tablets 1 mg, syrup, injections in ampoules for injection) drugs for the treatment of allergies in adults, children and pregnancy. Interaction with alcohol

In this article, you can read the instructions for using the drug Tavegil. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Tavegil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tavegil in the presence of existing structural analogues. Use for the treatment of allergies in adults, children, as well as in pregnancy and lactation.Interaction of the drug with alcohol.

Tavegil - blocker of histamine H1 receptors, ethanolamine derivative. Has antiallergic and antipruritic effect, reduces permeability of vessels, has a sedative and m-holinoblokiruyuschy effect, does not have hypnotic activity. Prevents development of vasodilation and contraction of smooth muscles, induced by histamine. Reduces the permeability of capillaries, inhibits exudation and formation of edema, reduces itching.

The antihistamine activity of the drug when ingested reaches a maximum after 5-7 hours, persists for 10-12 hours, and in some cases up to 24 hours.

Composition

Clemastine hydrofumarate + auxiliary substances.

Pharmacokinetics

After oral administration, Tavegil is almost completely absorbed from the digestive tract. Is allocated with breast milk in a small amount. Clemastin undergoes significant metabolism in the liver. Metabolites in the main (45-65%) are excreted in the urine; The unchanged active substance is found in urine only in trace amounts.

Indications

For the use of tablets:

• hay fever and other allergic rhinopathies;
• urticaria of various genesis;
• itching, itching dermatoses;
• acute and chronic eczema, contact dermatitis;
• drug allergy;
• bites and stings of insects.

To apply the solution for injection:

• anaphylactic or anaphylactoid shock and angioedema (as an additional agent);
• prevention or treatment of allergic and pseudo-allergic reactions (including with the introduction of contrast agents, blood transfusion, diagnostic use of histamine).

Forms of release

Tablets 1 mg.

Syrup.

Solution for intravenous and intramuscular injection (injections in ampoules for injection).

Instructions for use and dosage

Pills

Inside adults and children over 12 years of age appoint 1 tablet (1 mg) in the morning and evening. In cases that are difficult to treat, the daily dose can be up to 6 tablets (6 mg).

Children aged 6-12 years are prescribed 1 / 2-1 tablets before breakfast and at night.

Tablets should be taken before meals, washed down with water.

Syrup

Adults and children over 12 years of age are prescribed 10 ml of syrup (1 mg) in the morning and in the evening. In cases that are difficult to treat, the daily dose can be up to 60 ml of syrup (6 mg).

Children aged 6 to 12 years are prescribed 5-10 ml of syrup before breakfast and overnight.

Children aged 3 to 6 years are prescribed 5 ml 2 times a day before breakfast and at night.

Children aged 1 to 3 years are prescribed 2-2.5 ml 2 times a day before breakfast and at night.

It is recommended to dose the syrup with the supplied measuring cup.

Ampoules

Intramuscularly or intravenously, adults are prescribed 2 mg (2 ml, i.e., the contents of one ampoule).

For the purpose of prevention immediately before the possible occurrence of an anaphylactic reaction or reaction in response to the use of histamine, the drug is administered intravenously in a dose of 2 mg (2 ml). Solution for injection in the ampoule can be further diluted with isotonic sodium chloride solution or 5% glucose solution in a ratio of 1: 5. In / in Tavegil injection should be done slowly, for more than 2-3 minutes.

Children are prescribed at a dose of 25 mcg / kg per day in 2 injections.

Side effect

• drowsiness;
• increased fatigue;
• headache;
• dizziness;
• tremor;
• sedative effect;
• weakness;
• feeling tired;
• retardation;
• violation of coordination of movements;
• rarely, especially in children, there is a stimulating effect on the central nervous system, manifested by anxiety, increased irritability, agitation, nervousness, insomnia,hysteria, euphoria, convulsions, paresthesia;
• dyspepsia;
• nausea, vomiting;
• pain in epigastrium;
• constipation;
• dry mouth;
• decreased appetite;
• diarrhea;
• frequent urination;
• difficulty urinating;
• thickening of the bronchial secretion and difficulty in separating the sputum;
• feeling of pressure in the chest and difficulty breathing;
• nasal congestion;
• lowering blood pressure (usually in elderly patients);
• palpitation;
• extrasystole;
• hives;
• skin rash;
• anaphylactic shock;
• photosensitization;
• violation of clarity of visual perception;
• noise in ears;
• hemolytic anemia, thrombocytopenia, agranulocytosis.

Contraindications

• diseases of the lower respiratory tract (including bronchial asthma);
• simultaneous use of MAO inhibitors;
• children under 1 year of age (tablets should not be used in children under 6 years of age);
• lactation (breastfeeding);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

In pregnancy, Tavegil is used only if the expected benefit of therapy for the mother exceeds the potential risk to the fetus.

Tavegil should not be used during lactation,Clemastin in small amounts excreted in breast milk.

Use in children

Contraindicated for children under 1 year.

Children older than 1 year: 0.025 mg / kg per day intramuscularly, dividing into 2 injections.

special instructions

Intraarterial administration of Tavegil is not permitted.

To prevent distortion of skin scarification test results for allergens, the drug should be discontinued 72 hours before the allergy testing.

Impact on the ability to drive vehicles and manage mechanisms

Patients receiving Tavegil are advised to refrain from driving vehicles, working with mechanisms, as well as other activities requiring increased attention.

Drug Interactions

Tavegil potentiates the effect of drugs that depress the central nervous system (hypnotics, sedatives, tranquilizers), m-holinoblokatorov, as well as ethanol (alcohol).

Analogues of the drug Tavegil

Structural analogs for the active substance:

• Clemastine;
• Clemastin-Eskom;
• Rivtagil.

Similar medicines:

Other medicines: