Zodak - instructions for use, reviews, analogs and form of release (tablets 10 mg, syrup, drops for ingestion) of the drug for the treatment of allergies, rhinitis and conjunctivitis in adults, children and pregnancy. Composition and interaction with alcohol

In this article, you can read the instructions for using the drug Zodak. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Zodak in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Zodak with available structural analogues.Use for the treatment of allergies, rhinitis and conjunctivitis in adults, children, as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.

Zodak - antiallergic drug, blocker of histamine H1-receptors. Cetirizine belongs to the group of competitive antagonists of histamine. Has a pronounced anti-allergic effect, prevents development and facilitates the course of allergic reactions. Has antipruritic and antiexsudative effect. Affects the early stage of allergic reactions, and also reduces the migration of inflammatory cells; oppresses the selection of mediators involved in a late allergic reaction. Reduces the permeability of capillaries, prevents the development of edema of tissues, relieves spasm of smooth muscles. Eliminates the skin reaction to the administration of histamine, specific allergens, and also to cooling (with cold urticaria).

Virtually no anticholinergic and antiserotonin action.

In therapeutic doses, it practically does not have a sedative effect. Against the background of the course, tolerance does not develop.

The drug begins in 20 minutes (in 50% of patients) or after 1 hour (in 95% of patients) and persists for 24 hours.

Composition

Cetirizine dihydrochloride + excipients.

Pharmacokinetics

After ingestion Zodak quickly and almost completely absorbed from the digestive tract. Eating does not have a significant effect on the amount of absorption, but in this case, the rate of absorption is slightly reduced. Cetirizine does not penetrate the cell. Does not penetrate the blood-brain barrier (BBB). Cetirizine is poorly metabolized in the liver with the formation of an inactive metabolite. About 70% is excreted by the kidneys mostly unchanged.

Indications

• seasonal and year-round allergic rhinitis and conjunctivitis;
• itching allergic dermatoses;
• Pollinosis (hay fever);
• urticaria (including chronic idiopathic);
• angioedema.

Forms of release

The tablets covered with a cover of 10 mg.

Drops for oral administration.

Syrup.

Instructions for use and dosage

Pills

The drug Zodak is used according to the doctor's prescription in order to avoid complications.

Inside, regardless of food intake.

Adults and children over the age of 12 years

The drug Zodak, as a rule, appoint 1 tablet, coated with a shell, (10 mg cetirizine) 1 time per day.

Children aged 6 to 12 years

The drug Zodak, as a rule, is prescribed 1 tablet coated with a coating (10 mg cetirizine) once a day or 1/2 coated tablets, 5 mg cetirizine) 2 times a day, morning and evening.

Drops or syrup

The drug is administered orally, regardless of food intake. Before taking the drop, dissolve in water.

Adults and children over 12 years of age - 10 mg cetirizine (20 drops or 2 measuring spoons of syrup) 1 time per day, daily, preferably in the evening.

Children from 6 to 12 years - 10 mg cetirizine (20 drops or 2 measuring spoons of syrup) once a day or 5 mg cetirizine (10 drops or 1 measuring spoon) 2 times a day - in the morning and in the evening.

Children from 2 to 6 years - 5 mg cetirizine (10 drops or 1 measuring spoon syrup) 1 time per day, or 2.5 mg cetirizine (5 drops or 1/2 measuring spoon syrup) 2 times a day - in the morning and in the evening.

Children from 1 to 2 years - 2.5 mg (5 drops) 2 times a day.

In renal failure, the recommended dose should be reduced by a factor of 2.

In case of violations of liver function, the dose should be selected individually, reducing it to 5 mg per day or less, with extreme caution in case of simultaneous renal failure.

Older patients with normal renal function are not required to adjust the dose.

The rules for using a vial with a safety lid

The bottle is closed with a lid with a safety device that prevents its opening by children. The bottle opens when the lid is pressed hard down and then unscrewed against the clockwise direction. After use, the bottle cap must be tightened again tightly.

Side effect

• dry mouth;
• dyspepsia;
• headache;
• drowsiness;
• fatigue;
• dizziness;
• excitation;
• migraine;
• skin rash;
• angioedema;
• hives;
• itching.

Contraindications

• pregnancy;
• lactation period;
• Children under 1 year of age (drops for oral administration);
• children under 2 years of age (syrup);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The drug is contraindicated in pregnancy and lactation.

special instructions

It is not recommended simultaneous administration of drugs that have a depressing effect on the central nervous system, and the use of alcohol.

Strengthens (mutually) the de-adaptation and decrease in the rate of psychomotor reactions when using ethanol (alcohol); For the period of treatment it is necessary to abandon alcoholic beverages.

Drops for ingestion do not contain sugar (as a sweetener used saccharin), so this dosage form can be prescribed to patients with diabetes mellitus.

In 10 ml of syrup (2 measuring spoons) contains 3 g of sorbitol, which corresponds to 0.25 XE.

Impact on the ability to drive vehicles and manage mechanisms

During the treatment period, it is necessary to refrain from engaging in potentially dangerous activities that require a high concentration of attention and speed of psychomotor reactions.

Drug Interactions

There is no clinically significant interaction of Zodak with other drugs.

Joint application with theophylline (400 mg per day) leads to a decrease in the total clearance of cetirizine (theophylline kinetics does not change).

Analogs of the drug Zodak

Structural analogs for the active substance:

• Alerza;
• Allertec;
• Zincet;
• Zirtek;
• Lethisen;
• Parliamentary;
• Cetirizine;
• Cetirizine Hexal;
• Cetirizine-Teva;
• Cetirizine dihydrochloride;
• Cetirinax;
• Cetrin.

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