Pikamilon - instructions for use, analogs, reviews and release forms (tablets of 20 mg and 50 mg, injections in injections) of a drug for the treatment of stroke and encephalopathy in adults, children and pregnancy

In this article, you can read the instructions for using the drug Picalon. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Pikamilon in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Pikamilon analogues in the presence of existing structural analogues. Use for the treatment of stroke, encephalopathy and alcohol intoxication in adults, children,as well as during pregnancy and lactation.

Picalon - Nootropic agent, dilates the vessels of the brain. It also has a tranquilizing, psychostimulating, antiaggregant and antioxidant effect. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volume and linear speed of cerebral blood flow, reduces the resistance of cerebral vessels, inhibits platelet aggregation, improves microcirculation).

At the course reception increases physical and mental efficiency, reduces headache, improves memory, normalizes sleep; contributes to the reduction or disappearance of feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders.

Pharmacokinetics

Absorption is fast and complete, regardless of the route of administration. Penetrates through the blood-brain barrier (BBB), is retained for a long time in the tissues of the body. It is excreted mainly by the kidneys in unchanged form.

Indications

• cerebrovascular insufficiency, asthenia, depressive disorders in old age;
• states, accompanied by anxiety, fear, increased irritability, emotional lability. Asthenic conditions caused by various neuropsychic diseases;
• in the complex treatment - for the management of acute alcohol intoxication; with chronic alcoholism - to reduce asthenic, asthenoneurotic, postpsychotic, pre-recurrent conditions, as well as alcoholic encephalopathy.
• in the complex therapy - migraine (prevention), TBI, neuroinfection;
• Improving the portability of physical and mental loads (to persons in tense and extreme conditions of activity, to restore the physical performance of athletes, to increase resistance to physical and mental stress).
• Open-angle glaucoma (to stabilize the visual function);
• in urological practice (in children older than 3 years and in adults with urinary disorders) to improve the adaptive function of the bladder (reduction in hypoxia detrusor).

Forms of release

Tablets of 20 mg and 50 mg.

Solution for intravenous and intramuscular injection 10% (injections in ampoules for injection).

Instructions for use and reception scheme

Is taken orally, regardless of food intake.

In cerebrovascular diseases, a single dose of 20-50 mg 2-3 times a day, a daily dose of 60-150 mg. The course of treatment is 1-2 months. The second course is in 5-6 months.

Depressive states of late age: 40-200 mg per day for 2-3 doses, the optimal dose range is 60-120 mg per day for 1.5-3 months. As an anti-asthenic and anxiolytic agent - 40-80 mg per day, if necessary - up to 200-300 mg per day, for 1-1.5 months.

At an alcoholism during the period of an abstinence appoint in a dose of 100-150 mg a day, a short course of 6-7 days; with more persistent violations outside the abstinence - 40-60 mg per day for 4-5 weeks.

To restore efficiency and with increased loads - 60-80 mg per day for 1-1.5 months, for athletes in the same dose, for 2 weeks of training period.

Parenterally injected intravenously drip or jet (slow), intramuscularly.

With chronic disorders of cerebral circulation - in / in or / m, 100-200 mg 1-2 times a day, daily dose - 20-40 mg. Depending on the condition of the patient used in the morning in / in the drip, in the evening - in / m; or for 10 days in / in, then in / m. The course of treatment is 15-30 days.

For relief of acute uncomplicated intoxicationEthanol (alcohol) as part of complex therapy is administered at a saturating dose of 5 mg / kg and a maintenance dose of 1.56 mg / kg / h in a volume of 2.5 liters of the infusion solution, for 4 hours, in the morning and in the evening.

In asthenic conditions, depending on the severity of the disease, in addition to oral administration, I / m in a daily dose of 20-40 mg for 1 month.

Side effect

• irritability;
• excitation;
• anxiety;
• dizziness;
• headache;
• skin rash;
• itching;
• nausea.

Contraindications

• chronic renal failure;
• pregnancy;
• lactation period;
• increased sensitivity to nicotinoyl gamma-aminobutyric acid (picamilon).

Application in pregnancy and lactation

The drug is contraindicated in pregnancy and lactation.

special instructions

It is not recommended for severe degree of acute disturbance of cerebral circulation.

Drug Interactions

Pikamilon shortens the action of barbiturates, enhances the action of narcotic analgesics.

Analogues of the drug Picamalon

Structural analogs for the active substance:

• N-nicotinoyl-gamma-aminobutyric acid sodium salt;
• Amylonosar;
• Sodium salt of N-nicotinoyl gammaaminobutyric acid;
• Nicotinoyl gamma-aminobutyric acid;
• Pikamilona injection;
• Picanoyl;
• PikagoM.

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