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Loratadin - instructions for use, reviews, analogs and formulations (tablets 10 mg, effervescent, syrup 5 mg / ml) drugs for the treatment of allergies in adults, children and pregnancy. Action with alcohol

Loratadin - instructions for use, reviews, analogs and formulations (tablets 10 mg, effervescent, syrup 5 mg / ml) drugs for the treatment of allergies in adults, children and pregnancy. Action with alcohol

In this article, you can read the instructions for using the drug Loratadin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Loratadin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Loratadin in the presence of existing structural analogues. Use for the treatment of allergies in adults, children, as well as in pregnancy and lactation. Action of the drug with alcohol.

 

Loratadin - blocker of histamine H1-receptors (long-acting). Inhibits the release of histamine and leukotriene C4 from mast cells. Prevents development and facilitates the course of allergic reactions. It has antiallergic, antipruritic, antiexudative action. Reduces the permeability of capillaries, prevents the development of edema of tissues, relieves spasms of smooth muscles.

 

The antiallergic effect develops within 30 minutes, reaches a maximum after 8-12 hours and lasts for 24 hours. The duration of action is greatly enhanced by the active metabolite desloratadine. Does not affect the central nervous system and is not addictive (because it does not penetrate the blood-brain barrier (GEB)).

 

Pharmacokinetics

 

Quickly and completely absorbed into the digestive tract. Metabolized in the liver with the formation of an active metabolite deskarboksotiloratadina. Does not penetrate the BBB. It is excreted by the kidneys and with bile.

 

Indications

  • allergic rhinitis (seasonal and year-round);
  • conjunctivitis;
  • Pollinosis;
  • urticaria (including chronic idiopathic);
  • angioedema;
  • itching dermatoses;
  • pseudoallergic reactions;
  • allergic reactions to insect bites.

 

Forms of release

 

Tablets 10 mg.

 

Tablets effervescent 10 mg.

 

Syrup 5 mg / ml.

 

Instructions for use and dosage

 

Inside adults and children over 12 years of age, as well as with a body weight of more than 30 kg - 10 mg once a day.

 

Children from 2 to 12 years with a body weight of less than 30 kg - 5 mg 1 time per day.

 

For young children and adults with difficulty in swallowing, the use of a syrup is recommended.

 

Side effect

  • dry mouth;
  • change in taste;
  • anorexia;
  • constipation or diarrhea;
  • dyspepsia;
  • flatulence;
  • increased appetite;
  • stomatitis;
  • nausea, vomiting;
  • anxiety;
  • Excitement (in children);
  • asthenia;
  • drowsiness;
  • blepharospasm;
  • paresthesia;
  • tremor;
  • depression;
  • increased fatigue;
  • dermatitis;
  • alopecia;
  • change of color of urine;
  • painful urge to urinate;
  • dysmenorrhea;
  • menorrhagia;
  • increase in body weight;
  • sweating;
  • thirst;
  • cramps of the calf muscles;
  • cough;
  • bronchosiasm;
  • dryness of the nasal mucosa;
  • impaired vision;
  • conjunctivitis;
  • pain in the eyes and ears;
  • decrease or increase in blood pressure;
  • palpitation;
  • angioedema;
  • anaphylaxis;
  • hives;
  • itching;
  • rash;
  • photosensitization;
  • backache;
  • chest pain;
  • fever;
  • chills;
  • pain in the mammary glands.

 

Contraindications

  • pregnancy;
  • lactation period;
  • children's age up to 2 years;
  • hypersensitivity.

 

Application in pregnancy and lactation

 

Contraindicated.

 

Use in children

 

For young children and adults with difficulty in swallowing, the use of a syrup is recommended.

 

Children from 2 to 6 years (with a body weight of less than 30 kg): 5 mg (1 measuring spoon (5 ml) syrup) 1 time per day.

 

Children over 6 years old (weighing more than 30 kg) and adults: 10 mg (2 scoops (10 ml) syrup, or 1 tablet, or 1 tablet effervescent) 1 time per day.

 

Contraindicated in children under 2 years.

 

special instructions

 

During the treatment period, it is necessary to refrain from engaging in potentially dangerous activities that require a high concentration of attention and speed of psychomotor reactions.

 

Drug Interactions

 

Erythromycin, cimetidine, Ketoconazole increase the concentration of loratadine in the blood plasma, without causing clinical manifestations and without affecting the ECG.

 

Inducers of microsomal oxidation (phenytoin, ethanol (alcohol), barbiturates, zixorin, rifampicin, phenylbutazone, tricyclic antidepressants) decrease the effectiveness of loratadine.

 

Analogues of Loratadin

 

Structural analogs for the active substance:

  • Alerpriv;
  • Vero-Loratadine;
  • Clallergine;
  • Clargotil;
  • Claridol;
  • Claricens;
  • Claritin;
  • Clarifer;
  • Clarotadine;
  • Lomilan;
  • Lomilan Solo;
  • LoraGexal;
  • Loratadine 10-SL;
  • Loratadine-OBL;
  • Loratadin-Verte;
  • Loratadin-Teva;
  • Loratadine-Hemofarm;
  • Loratadin-Stade;
  • Lotharen;
  • Tyrror;
  • Erolin.

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Reviews (7):
Guests
Julia
The prevalence of allergy in the modern world begins to frighten. Even people who until recently did not know what it was, more often find themselves in unpleasant symptoms. And my husband was no exception. Already 4 years in the summer he is allergic to flowering plants. At first, he did not pay much attention, he periodically bought various antihistamines in the pharmacy, but they did not give noticeable results. The time has come when, due to the constant stuffiness of the nose and the terribly inflamed eyes, it became difficult to work. Finally I asked for medical help. The doctor appointed Loratadin. As it turned out, he has a number of advantages. The first, pleasantly pleased the cost of the drug, with the current order of prices for medicines, consider - a gift.Second, one reception per day is sufficient, which is a huge plus for my husband-the "sclerophore", counting the times of admission and keeping the schedule-for him it is an unbearable occupation. And thirdly, the spouse lacks significant side effects. Light and unstable dryness in the mouth is the only trouble that, compared with the normal state of health after prolonged anguish, is just a trifle. And the lack of sleepiness, which is also essential.

Still Loratadin gave a 5 year old daughter, when she was bitten by the mosquitoes on the sea with a passion. One half of the tablet took off the itch and swelling. Plus, additionally applied to affected areas ointment Fenistil. In the complex it turned out well, the child stopped combing his bites, apparently, the itch completely disappeared.
Guests
Chernichka
Claritin was over, and money was right next to me, I had to buy Loratadin, surprisingly in the pharmacy they did not discourage him, and helped, in Claritine, the active substance - Loratadine and the same 10 mg. Now I will check for drowsiness, tk. In the morning, Claritin had already drunk, helped, but not enough, so an hour later she took Loratadin, that is, the dose is already 20 mg. It turned out, while it seems to be normal, let's see what happens, becausefrom tablets of type Suprastin I fall asleep at once, for a long time and I can not wake up.
Administrators
admin
ChernichkaIt should be neat with self-combinatorial treatment, given that the drugs you take are similar. In the morning one drug, in the evening another, but from the same group and it is possible to harm the body. Be careful and consult a doctor.
Guests
Anna Ivanenko
I've also tried loratadine for an allergy not long ago. Well and that, I think, import tablets have risen in price very much, and ours - nothing is worse, really the acting substance that one and the same. And the tablets were really good. They help nothing worse than imported analogues.
Guests
Lydia Fyodorovna
Loratadin is our domestic drug, which knowledgeable people have used for many, many years. It is cheap and therefore not subject to advertising, unlike imported ones, and those who under various invented brands ("teva" for example) break prices. Loratadin always cost a penny, but once one "smart guy" add the word "teva" to determine the drug in another package and the price has risen very noticeably.And the active substance of the drug is the same. People! Be smarter, do not get fooled by expensive advertised drugs, most of them have our domestic counterparts and many of them are even better than imported ones: the active ingredient is the same, the price is much lower, the tablets are larger in packaging.
Guests
Kamkuch
Three years I accept an omniq from BPH. There was a flaky rash all over the body with a white touch. It itches very much during the day, at night the itch subsides. Plaques, mostly on the head, in the ears, on the buttocks. I think that this is an allergy from an omni. The dermatologist did not determine the exact diagnosis. I save myself with an acryram or a white-skinned woman. Plaques disappear, then appear in the same place. Will loratadine help me and how long does it take? Thank you.
Administrators
admin
Kamkuch, Try to cancel for 3-4 days Omnik and see what will happen to your allergy. If skin manifestations disappear, then contact the urologist to replace this drug with another, which will be deprived of such a side effect. Fighting a drug allergy with another medicine is a hopeless activity and I do not advise you to do it.If the allergy is not related to the medication, then a standard examination for allergens with sample preparation, liver examination, allergist consultation and treatment, including antihistamines such as Loratadine, may be prescribed.

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