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Suprax - instructions for use, analogs, reviews and release forms (capsules or tablets 200 mg and 400 mg, suspension or syrup) drugs for the treatment of sore throats, pharyngitis and sinusitis in adults, children and pregnancy. Composition of antibiotic

Suprax - instructions for use, analogs, reviews and release forms (capsules or tablets 200 mg and 400 mg, suspension or syrup) drugs for the treatment of sore throats, pharyngitis and sinusitis in adults, children and pregnancy. Composition of antibiotic

In this article, you can read the instructions for using the drug Suprax. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Suprax in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of the antibiotic Suprax in the presence of existing structural analogues.Use for the treatment of angina, pharyngitis and sinusitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

 

Suprax - Semisynthetic cephalosporin antibiotic of a broad spectrum of action of 3 generations for oral administration. It is bactericidal. The mechanism of action is due to the inhibition of the synthesis of the cell membrane of the pathogen. Cefixime is resistant to the action of beta-lactamases produced by most gram-positive and gram-negative bacteria.

 

In vitro and in clinical practice, Suprax is active against gram-positive and gram-negative bacteria.

 

The drug is resistant to Pseudomonas spp., Enterococcus (Streptococcus) serogroup D, Listeria monocytogenes, Staphylococcus spp. (including methicillin-resistant strains), Enterobacter spp., Bacteroides fragilis, Clostridium spp.

 

Composition

 

Cefixime (in the form of trihydrate) + auxiliary substances.

 

Pharmacokinetics

 

When administered orally, the bioavailability of Suprax is 40-50% regardless of food intake. The binding with plasma proteins, mainly with albumins, is 65%. About 50% of the dose is excreted in the urine unchanged for 24 hours, about 10% of the dose is excreted with bile.

 

Indications

 

Infectious-inflammatory diseases caused by microorganisms sensitive to the preparation:

  • pharyngitis;
  • tonsillitis;
  • sinusitis;
  • acute and chronic bronchitis;
  • otitis media;
  • uncomplicated urinary tract infections;
  • uncomplicated gonorrhea.

 

Forms of release

 

Capsules 200 mg and 400 mg (forms of release in the form of tablets do not exist).

 

Granules for the preparation of a suspension for oral administration (the ideal pediatric form of the drug, sometimes mistakenly called syrup).

 

Instructions for use and dosing regimen

 

For adults and children over 12 years of age with a body weight of more than 50 kg, the daily dose is 400 mg once a day. The duration of the course of treatment is 7-10 days.

 

With uncomplicated gonorrhea prescribed 400 mg once.

 

For children under 12 years of age, the drug is administered in the form of a suspension at a dose of 8 mg / kg body weight once a day or 4 mg / kg every 12 hours.

 

Children aged 5-11 years, the daily dose is 6-10 ml of the suspension, at the age of 2-4 years - 5 ml, at the age of 6 months to 1 year - 2.5-4 ml.

 

For infections caused by Streptococcus pyogenes, the course of treatment should be at least 10 days.

 

In case of violations of kidney function (with CC from 21 to 60 ml / min) or in patients on hemodialysis, the daily dose should be reduced by 25%.

 

At CC ≤20 ml / min or in patients on peritoneal dialysis, the daily dose should be reduced by 2 times.

 

Patients with renal dysfunction with KK less than 60 ml / min,which is on hemodialysis or peritoneal dialysis, the drug should be administered in the form of a suspension.

 

Rules for the preparation of suspension

 

Turn the vial and shake the granules. Add 40 ml of boiled water cooled to room temperature in 2 stages and shake after each addition until a homogeneous suspension forms. After this, it is necessary to allow the suspensions to settle for 5 minutes to ensure complete disintegration of the granules. Before use, the prepared suspension should be shaken.

 

Side effect

  • dry mouth;
  • anorexia;
  • nausea, vomiting;
  • diarrhea;
  • constipation;
  • stomach ache;
  • flatulence;
  • Candidiasis of the gastrointestinal tract;
  • dysbiosis;
  • stomatitis;
  • glossitis;
  • pseudomembranous enterocolitis;
  • leukopenia, thrombocytopenia, neutropenia, hemolytic anemia, pancytopenia, aplastic anemia;
  • dizziness;
  • headache;
  • impaired renal function;
  • acute renal insufficiency;
  • itching;
  • hives;
  • hyperemia of the skin;
  • eosinophilia;
  • fever;
  • exudative erythema multiforme;
  • toxic epidermal necrolysis;
  • anaphylactic shock;
  • dyspnea;
  • development of hypovitaminosis B.

 

Contraindications

  • renal dysfunction with KK less than 60 ml / min (for capsules);
  • children under 12 years (for capsules);
  • increased sensitivity to cephalosporins and penicillins.

 

Application in pregnancy and lactation

 

The use of Suprax during pregnancy is possible only if the intended benefit to the mother exceeds the potential risk to the fetus.

 

If you need supraksa during lactation should stop breastfeeding.

 

Use in children

 

Caution should be given to suprax in children under 6 months of age.

 

Children up to the age of 12 years, the drug is prescribed as a suspension at a dose of 8 mg / kg body weight once a day or 4 mg / kg every 12 hours.

 

Children aged 5-11 years, the daily dose is 6-10 ml of the suspension, at the age of 2-4 years - 5 ml, at the age of 6 months to 1 year - 2.5-4 ml.

 

special instructions

 

With prolonged use of the drug, a violation of normal intestinal microflora is possible, which can lead to the growth of Clostridium difficile and cause the development of severe diarrhea and pseudomembranous colitis.

 

Patients with a history of allergic reactions to penicillins may exhibit increased sensitivity to cephalosporin antibiotics.

 

During treatment, a positive direct Coombs reaction and a false positive urine reaction to glucose are possible.

 

Impact on the ability to drive vehicles and manage mechanisms

 

Patients taking cefixime should be careful in driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions, taking into account the profile of side effects.

 

Drug Interactions

 

The tubular secretion blockers (allopurinol, diuretics) delay the excretion of cefixin by the kidneys, which can lead to an increase in the concentration of the drug in the blood plasma.

 

With the simultaneous use of Suprax and carbamazepine, the concentration of Carbamazepine in the blood plasma increases.

 

Reduces the prothrombin index, increases the effect of indirect anticoagulants.

 

Antacids containing magnesium or aluminum hydroxide, slow the absorption of the drug, so the drug should be used 1-2 hours before or 4 hours after taking these medications.

 

Analogues of Suprax

 

Structural analogs for the active substance:

  • Ixim Lupine;
  • Panzef;
  • Cemidexor;
  • Ceforal Solutab;
  • Cefspan.

Similar medicines:

Other medicines:
Reviews (24):
Guests
Alina
I work as a guide, the vocal cords are constantly stressed. This fall, problems with the throat began: in the morning, persecution, towards the evening, pain, but the most terrible - the voice became hoarse, and when my work is a disaster. Has addressed in an out-patient department, the doctor has diagnosed - a chronic pharyngitis. We started treatment. Aflubin and imudon the proper effect was not given. Only the suprax helped. Within 4 days after taking this medication, a sore throat passed. Of course, side effects (such as diarrhea) could not be avoided, but this is understandable - after all, suprax is considered a very strong antibiotic. However, after the course of treatment was over, and the intestines quickly calmed down. And in the main suprax helped me - and my throat stopped hurting, and my voice recovered.
Guests
Irina
The doctor diagnosed a bilateral sinusitis. Appointed Supraks, great help!
Administrators
admin
Question from the visitor ND1982 moved to the required section:
Hello, tell me my suspicion of cystitis and urolithiasis often ran to the toilet. So far, ultrasound has not been prescribed antibiotic Supraks-salutab, very expensive. I have amoxicillin at home. He, too, a broad sector of the action, can I drink it? I was prescribed a dose of 1t per day. If there is no can tell me an analogue that suits me ?! Thanks in advance.

ND1982, For the diagnosis of cystitis it is better to pass a general urine test, will be more informative than ultrasound. For urolithiasis, of course, it is necessary and ultrasound to pass.

About the replacement of expensive Supraksa Amoxicillin, remotely we will not do so. I generally like to start primary cystitis therapy with inexpensive Furagin and other derivatives of the furan group, but if the cystitis is started, then from a group of third-generation cephalosporins (to which Supraks refers), antibiotics (not all of them in tablets or capsules,more injectable forms and more domestic or Indian counterparts by origin): Cefabol, Cefatrine, Cefoperazone, Cefosin, Cefotaxime and the most popular ceftriaxone.
Guests
Timothy
Supraks, great help!
Guests
Olga
Lor has diagnosed: otitis and inflammation of the trigeminal nerve. Has written out Supraks 400 on 1 caps. 2 times / day. within 5 days. I drank 3 days, bought a new package and only then read the instruction, which says that 1 capsule per day for 7 to 10 days. I do not know whether to reduce the dose, will not it be worse? This I was poisoned with a lethal dose of 3 days! The microflora of the intestine probably dies, although I drink bifiform.
Laura at the reception said that there was no Rise, only the ear hurt, the jaw joint on the left - it's painful to touch. But the trigeminal nerve does not treat like a \ b. The girlfriend was prescribed finlepsin.
So, the ENT itself does not know how to properly appoint? On rolled, as in most cases, appoint 1 to 2 p. Days.?
In addition, she prescribed drops with a / b in the ear, a turunda with boric acid, hydrocortisone and levomecovol ointment in the evening. In short, otitis is lethal.
Administrators
admin
Olga, Dosage and really your doctor is too big. If the drug allows an increase in the average therapeutic dosages, then this is clearly indicated in the instructions. In your case, then there would be a fork for taking a medication for a daily intake of 400 mg - 800 mg, but in the instructions for the antibiotic Supraks is not like that. Considering that you drank it for 3 days, take it as it is, because if you lower the concentration of the antibiotic now, then you can reactivate the injection. Probably, your ENT is based on your experience of using the drug, but it is wrong.
Guests
OTITIS
Saw 400mg 2 r \ day for 5.5 days. Laurus said that the otitis is not cured. So it did not fit a \ b, despite the slaughter dose. Spent 1.5 thousand rubles. And besides that, there was a drop in the norm.
Guests
Galina
Very satisfied with Suprax. The child had a terrible angina, only Supraks helped.
Guests
Alexandra
The drug was prescribed to the child for 6 years. Absolutely did not help, but only made it worse.The child was covered with a rash, the kidneys did not cope - the baby was swelling. There was a conjunctivitis. In general, the drug is disgusting and I think it is dangerous for children.
Guests
Deimonys
I take Suprapax 400 mg, already the second time and again with a purulent angina, and he does an excellent job. The truth for the second time there were pobochki: a rash on the hands, skin itch.
Guests
DariaL
The child was 2 years old, hospitalized with acute laryngitis plus otitis media. The temperature is under 40, if not knocked over. On the third day, antibiotics were prescribed. They gave me a choice orally or injections. I chose it orally, because I read that in 3 and above the generation there are no special drawbacks compared to the injections (Supraks was appointed). Yesterday was the first reception, today is the second. While the effect is not present and the doctor insists on nyxes. But can there be an effect when not even a day has passed yet? And with the change of antibiotic now is not developed resistance to supraksu (they want to change the antibiotic of the same group, injected intravenously).
Administrators
admin
DariaL, I would have taken the third day and if there is no speaker, then it really is worth changing the antibiotic or the way it is delivered to the baby's body. Two days such a period that may not have time to work out an antibiotic, on the third day, at least something should be noticeable.
Guests
DariaL
As a result, by the evening of the second day, the antibiotic acted, we continue it.
Visitors
123456789
Hello. To me have appointed or nominated Supraks at a pyelonephritis. Can I drink it today at night, and take the next pill in 12 hours? Or is it better to drink then every night? And whether it is possible to accept it or him together with nurofenom as strong pains and temperature !?
Administrators
admin
123456789If you start taking Suprax in the evening, then in the evening and on other days, take it. So it will be right to take at the same time. With Nurofen this antibiotic is combined and there should not be negative side effects when used together.
Visitors
123456789
Yesterday I drank suprax for the night, today all day dizziness and nausea. Is it a side effect or because of pyelonephritis? I do not even know how to proceed?
Administrators
admin
123456789If side effects are tolerable, you can continue treatment, if not - then contact your doctor who appointed Suprax to replace the antibiotic with another. These side effects may give this medicine.
Guests
Katerina
And he did not help me ...
Guests
Masrach
Hello. To the child 4 months the temperature is 37-37,8. There are no other signs of the disease, they have passed the analysis - leucocytes are increased. The diagnosis is a viral infection. Have registered supraks 1,5 ml for time. Need such a strong drug?
Administrators
admin
Masrach, In case of a viral infection, the use of antibiotics is not advisable. Most likely your doctor does not have a clear diagnosis, so he appoints everything in order to get a finger in the sky. I would recommend consulting another specialist.
Guests
Aida
To the child 3 years. We were diagnosed with angina, appointed Supraks, the third day I give it and the temperature is still high.
Visitors
Martha
Hello. When bronchitis the doctor prescribed suprax 400 mg 1p./d, but did not say anything about probiotics. In the home medicine cabinet is Florin Forte, tell me, please, how correctly to take an a / b and probiotic: together or separately and with what interval.
Administrators
admin
Martha, Probiotics and antibiotics are prescribed together only with the development of dysbacteriosis (diarrhea, flatulence, abdominal pain and other symptoms), but without antibiotic cancellation therapy will not be so effective, because the antibiotic destroys both harmful and beneficial bacteria in the body. Therefore, I assign eubiotics and probiotics to my patient after taking antibiotics, and the majority of patients will have enough kefir or better live curdled milk after the course of treatment.
Guests
Nikolay Samara.
I drank 6 tablets. For 400 ml. one per day. (appointed after surgery). One week later, an itchy groin in the groin (an operative removal of the testicle cyst) on the palms of the palms, between the fingers, on the left cheekbone of the face, an allergic rash with blisters.

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