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Amitriptyline - instructions for use, reviews, analogs and formulations (tablets and pills 10 mg and 25 mg, injections in ampoules) of a drug for the treatment of depression and psychosis in adults, children and pregnancy. Combination with alcohol

Amitriptyline - instructions for use, reviews, analogs and formulations (tablets and pills 10 mg and 25 mg, injections in ampoules) of a drug for the treatment of depression and psychosis in adults, children and pregnancy. Combination with alcohol

In this article, you can read the instructions for using the drug Amitriptyline. There are reviews of visitors to the site - consumers of this medication, as well as the opinions of doctors of specialists on the use of Amitriptyline in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Amitriptyline in the presence of existing structural analogues.Use to treat depression, psychosis and schizophrenia in adults, children, as well as in pregnancy and lactation. Combination of the drug with alcohol.

 

Amitriptyline antidepressant (tricyclic antidepressant). It also has some analgesic (central genesis), antiserotonin action, helps to eliminate night incontinence and reduces appetite.

 

Has a strong peripheral and central anticholinergic action due to high affinity for m-holinoretseptoram; a strong sedative effect associated with affinity for H1-histamine receptors, and an alpha-adrenergic blocking action.

 

Has the properties of antiarrhythmic drug class IA, like quinidine in therapeutic doses, slows down the ventricular conduction (in case of an overdose it can cause severe intraventricular blockade).

 

The mechanism of antidepressant action is associated with an increase in the concentration of noradrenaline and / or serotonin in the central nervous system (CNS) (a decrease in their reverse absorption).

 

Accumulation of these neurotransmitters occurs as a result of inhibition of their inverse capture by the membranes of presynaptic neurons.With prolonged use reduces the functional activity of beta-adrenergic and serotonin receptors in the brain, normalizes adrenergic and serotonergic transmission, restores the balance of these systems, disturbed in depressive states. With anxiety-depressive states reduces anxiety, agitation and depressive manifestations.

 

The mechanism of antiulcer action is due to the ability to exert sedative and m-anticholinergic action. Efficacy at night urinary incontinence is apparently due to anticholinergic activity leading to increased bladder capacity for stretching, direct beta adrenergic stimulation, alpha-adrenergic agonist activity accompanied by increased sphincter tone, and central blockade of serotonin uptake. Has a central analgesic effect, which is believed to be associated with changes in the concentration of monoamines in the central nervous system, especially serotonin, and influence on endogenous opioid systems.

 

The mechanism of action for bulimia nervosa is unclear (it may be similar to that in depression).It shows a distinct effect of the drug with bulimia in patients with both depression and its presence, while a decrease in bulimia can be noted without the concomitant weakening of depression itself.

 

When general anesthesia reduces blood pressure and body temperature. Does not inhibit monoamine oxidase (MAO).

 

Antidepressant effect develops within 2-3 weeks after the beginning of application.

 

Pharmacokinetics

 

Absorption is high. Passes (including nortriptyline - amitriptyline metabolite) through the histohematetic barriers, including the blood-brain barrier, placental barrier, penetrates into breast milk. It is excreted by the kidneys (mainly in the form of metabolites) - 80% in 2 weeks, in part with bile.

 

Indications

  • depression (especially with anxiety, agitation and sleep disorders, including in childhood, endogenous, involutional, reactive, neurotic, drug, with organic brain lesions);
  • as part of complex therapy used in mixed emotional disorders, psychoses in schizophrenia, alcohol withdrawal, behavioral disorders (activity and attention), nocturnal enuresis (except for patients with bladder hypotension), bulimia nervosa,chronic pain syndrome (chronic pain in cancer patients, migraine, rheumatic diseases, atypical pain in the face, postherpetic neuralgia, posttraumatic neuropathy, diabetic or other peripheral neuropathy), headache, migraine (prophylaxis), gastric ulcer and 12-finger guts.

 

Forms of release

 

Tablets 10 mg and 25 mg.

 

Dragee 25 mg.

 

Solution for intravenous and intramuscular injection (injections in ampoules for injection).

 

Instructions for use and dosage

 

Assign inside, not liquid, immediately after meals (to reduce irritation of the gastric mucosa).

 

Adults

 

Adults with depression, the initial dose - 25-50 mg per night, then gradually the dose can be increased taking into account the effectiveness and tolerability of the drug to a maximum of 300 mg per day in 3 divided doses (most of the dose is taken at night). When the therapeutic effect is achieved, the dose can be gradually reduced to the minimum effective depending on the patient's condition. The duration of the course of treatment is determined by the patient's condition, effectiveness and tolerability of the therapy and can range from several months to 1 year, and, if necessary, more.In old age, when light violations, as well as nervous bulimia, in combined therapy with mixed emotional disorders and behavioral disorders, psychoses, schizophrenia and alcohol withdrawal administered in a dose of 25-100 mg daily (at night), after moving the therapeutic effect at minimal effective doses - 10-50 mg per day.

 

For the prevention of migraine, chronic pain syndrome, neurogenic character (including long headaches), as well as in the treatment of gastric ulcer and duodenum 12 - from 10-12.5-25 to 100 mg per day (maximum dose portion taken at night).

 

Children

 

Babies as an antidepressant: 6 to 12 years - 10-30 mg per day, or 1-5 mg / kg per day fractional, a teenager - to 100 mg per day.

 

When nocturnal enuresis in children 6-10 years - 10-20 mg per day at night, 11-16 years - up to 50 mg per day.

 

Side effect

  • blurred vision;
  • mydriasis;
  • increased intraocular pressure (only in individuals with a local anatomical predisposition - a narrow angle of the anterior chamber);
  • drowsiness;
  • fainting;
  • fatigue;
  • irritability;
  • anxiety;
  • disorientation;
  • hallucinations (especially in elderly patients and patients with Parkinson's disease);
  • anxiety;
  • mania;
  • memory impairment;
  • decreased ability to concentrate;
  • insomnia;
  • "nightmarish" dreams;
  • asthenia;
  • headache;
  • ataxia;
  • increase and intensification of epileptic seizures;
  • changes on the electroencephalogram (EEG);
  • tachycardia;
  • a feeling of palpitations;
  • dizziness;
  • orthostatic hypotension;
  • arrhythmia;
  • lability of blood pressure (decrease or increase in blood pressure);
  • dry mouth;
  • constipation;
  • nausea, vomiting;
  • heartburn;
  • gastralgia;
  • increased appetite and body weight or decreased appetite and body weight;
  • stomatitis;
  • change in taste;
  • diarrhea;
  • darkening of the tongue;
  • an increase in the size (swelling) of the testicles;
  • gynecomastia;
  • increase in the size of the mammary glands;
  • galactorrhea;
  • decreased or increased libido;
  • decreased potency;
  • skin rash;
  • itching;
  • photosensitization;
  • angioedema;
  • hives;
  • hair loss;
  • noise in ears;
  • edema;
  • hyperpyrexia;
  • enlarged lymph nodes;
  • retention of urine.

 

Contraindications

  • hypersensitivity;
  • application in conjunction with MAO inhibitors and 2 weeks before the start of treatment;
  • myocardial infarction (acute and subacute periods);
  • acute alcohol intoxication;
  • acute intoxication with hypnotics, analgesics and psychoactive drugs;
  • angle-closure glaucoma;
  • severe disturbances of AV and intraventricular conduction (blockade of the bundle of the bundle, AV blockade of 2 items);
  • lactation period;
  • children's age till 6 years;
  • intolerance to galactose;
  • deficiency of lactase;
  • glucose-galactose malabsorption.

 

Application in pregnancy and lactation

 

In pregnant women, the drug should be used only if the intended benefit to the mother exceeds the potential risk to the fetus.

 

Penetrates into breast milk and can cause drowsiness in infants. To avoid the development of the "cancellation" syndrome in newborns (manifested by shortness of breath, drowsiness, intestinal colic, increased nervous excitability, increase or decrease in blood pressure, tremor, or spastic phenomena), amitriptyline is gradually withdrawn at least 7 weeks before the expected delivery.

 

Use in children

 

Contraindicated in children under 6 years.

 

In children, adolescents and young people (under 24 years) with depression and other mental disorders, antidepressants, compared with placebo, increase the risk of suicidal thoughts and suicidal behavior. Therefore, with the appointment of amitriptyline or any other.antidepressants in this category of patients, it is necessary to correlate the risk of suicide and the benefit from their use

 

special instructions

 

Before the start of treatment, it is necessary to control blood pressure (in patients with low or labile blood pressure it can decrease even more); in the period of treatment - control of peripheral blood (in some cases, agranulocytosis may develop, and therefore it is recommended to monitor the blood picture, especially with an increase in body temperature, the development of influenza-like symptoms and sore throats), with prolonged therapy - control of the functions of the CCC and liver. In the elderly and patients with SSS diseases, control of heart rate, blood pressure, and ECG is shown. On the ECG, there may be clinically insignificant changes (T wave smoothing, S-T segment depression, QRS complex expansion).

 

Care must be taken when jumping to a vertical position from the "lying" or "sitting" position.

 

During the treatment should be excluded from the use of ethanol.

 

Assign no earlier than 14 days after the abolition of MAO inhibitors, starting with small doses.

 

With a sudden discontinuation after long-term treatment, the syndrome of "withdrawal" may develop.

 

Amitriptyline in doses above 150 mg per day reduces the threshold of convulsive activity (it should take into account the risk of epileptic attacks in predisposed patients, as well as in the presence of other predisposing factors to the emergence of convulsive syndrome, for example, brain damage of any etiology, simultaneous use of antipsychotic drugs (neuroleptics ), during the period of rejection of ethanol or withdrawal of drugs with anticonvulsant properties, for example, benzodiazepines). Depression is characterized by the risk of suicidal actions, which can persist until a significant remission is achieved. In this regard, at the beginning of treatment, a combination with drugs from the benzodiazepine group or neuroleptic drugs and continuous medical monitoring (entrusting trusted persons with storage and dispensing of medicines) may be indicated. In children, adolescents and young people (under 24 years) with depression and other mental disorders, antidepressants, compared with placebo, increase the risk of suicidal thoughts and suicidal behavior. Therefore, with the appointment of amitriptyline or any other.antidepressants in this category of patients should be related to the risk of suicide and the benefits of their use. In short-term studies in people over 24 years of age, the risk of suicide did not increase, but in people older than 65 years, it declined slightly. During treatment with antidepressants, all patients should be monitored for early detection of suicidal tendencies.

 

In patients with cyclical affective disorders in the period of the depressive phase, manic or hypomanic conditions may develop on the background of therapy (dose reduction or drug withdrawal and antipsychotic drug administration are necessary). After the relief of these conditions, if there are indications, treatment at low doses can be resumed.

 

Due to possible cardiotoxic effects, care must be taken when treating patients with thyrotoxicosis or patients receiving thyroid hormone preparations.

 

In combination with electroconvulsive therapy is prescribed only under the condition of careful medical supervision.

 

At predisposed patients and patients of advanced age can provoke development of medicinal psychoses,mainly at night (after the drug is withdrawn for several days).

 

May cause paralytic intestinal obstruction, mainly in patients with chronic constipation, the elderly or in patients who are obliged to comply with bed rest.

 

Before conducting general or local anesthesia, an anesthesiologist should be warned that the patient is taking amitriptyline.

 

Due to the anticholinergic effect, tearing can be reduced and the relative amount of mucus in the tear fluid can be increased, which can damage the epithelium of the cornea in patients using contact lenses.

 

With prolonged use, there is an increase in the frequency of tooth decay. The need for riboflavin may be increased.

 

The study of reproduction on animals has revealed an unfavorable effect on the fetus, and adequate and strictly controlled studies in pregnant women have not been conducted. In pregnant women, the drug should be used only if the intended benefit to the mother exceeds the potential risk to the fetus.

 

Penetrates into breast milk and can cause drowsiness in infants. To avoid the development of the "cancellation" syndrome in newborns (manifested by shortness of breath, drowsiness, intestinal colic, increased nervous excitability, increase or decrease in blood pressure, tremor, or spastic phenomena), amitriptyline is gradually withdrawn at least 7 weeks before the expected delivery.

 

Children are more sensitive to acute overdose, which should be considered dangerous and potentially fatal for them.

 

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

 

Drug Interactions

 

With the joint use of ethanol (alcohol) and drugs, depressing the central nervous system (including other antidepressants, barbiturates, benzadiazepines and general anesthetics), a significant increase in the inhibitory effect on the central nervous system, respiratory depression and hypotensive effect. Increases the sensitivity to beverages containing ethanol (alcohol).

 

Increases anticholinergic drugs with anticholinergic activity (e.g., phenothiazine derivatives, antiparkinsonian drugs, amantadine, atropine, biperiden, antihistaminic drugs), which increases the risk of side effects (CNS, vision, and bladder intestine). When combined with the use holinoblokatorami, derivatives of phenothiazine and benzodiazepine - mutual enhancement of sedation and central anticholinergic effects and increase the risk of seizures (seizure threshold reduction); derivatives of phenothiazine, in addition, may increase the risk of neuroleptic malignant syndrome.

 

When combined with anticonvulsant drugs, it is possible to increase the inhibitory effect on the central nervous system, reduce the threshold of convulsive activity (when used in high doses), and reduce the effectiveness of the latter.

 

When combined with antihistamine drugs, clonidine - increased oppressive effect on the central nervous system; with atropine - increases the risk of paralytic intestinal obstruction; with medicines,causing extrapyramidal reactions - an increase in the severity and frequency of extrapyramidal effects.

 

With the simultaneous use of amitriptyline and indirect anticoagulants (coumarin derivatives or indadion), an increase in anticoagulant activity of the latter is possible. Amitriptyline may increase depression caused by glucocorticosteroids (GCS). Drugs for the treatment of thyrotoxicosis increase the risk of agranulocytosis. Reduces the effectiveness of phenytoin and alpha-blockers.

 

Inhibitors of microsomal oxidation (cimetidine) prolong T1 / 2, increase the risk of developing toxic effects of amitriptyline (a 20-30% dose reduction may be required), inducers of microsomal liver enzymes (barbiturates, carbamazepine, phenytoin, nicotine and oral contraceptives) reduce plasma concentration and reduce the effectiveness of amitriptyline.

 

Joint use with Disulfiram and other inhibitors of acetaldehyde genase provokes delirium.

 

Fluoxetine and fluvoxamine increase the concentration of amitriptyline in plasma (a decrease in the dose of amitriptyline by 50% may be required).

 

Estrogen-containing oral contraceptive medications and estrogens can increase the bioavailability of amitriptyline.

 

With the simultaneous use of amitriptyline with clonidine, guanethidine, betanidine, reserpine and methyldopa - reducing the hypotensive effect of the latter; with cocaine - the risk of arrhythmia of the heart.

 

Antiarrhythmic drugs (such as quinidine) increase the risk of developing rhythm disturbances (possibly slowing the metabolism of amitriptyline).

 

Pimozide and probucol may increase cardiac arrhythmias, which is manifested in the prolongation of the Q-T interval on the ECG.

 

Strengthens the effect on the CCC of epinephrine, norepinephrine, isoprenaline, Ephedrine and phenylephrine (including when these drugs are part of local anesthetics) and increases the risk of heart rhythm disturbances, tachycardia, severe arterial hypertension.

 

When co-administered with alpha-adrenomimetics for intranasal administration or for use in ophthalmology (with significant systemic absorption), the vasoconstrictor effect of the latter may be enhanced.

 

With a joint admission with thyroid hormones - a mutual enhancement of the therapeutic effect and toxic effects (include cardiac arrhythmias and a stimulating effect on the central nervous system).

 

M-holinoblokatory and antipsychotic drugs (neuroleptics) increase the risk of hyperpyrexia (especially in hot weather).

 

When co-administered with other hematotoxic drugs, it is possible to increase hematotoxicity.

 

Incompatible with MAO inhibitors (there may be an increase in the frequency of periods of hyperpyrexia, severe seizures, hypertensive crises and death of the patient).

 

Analogs of the drug Amitriptyline

 

Structural analogs for the active substance:

  • Amizole;
  • Amirol;
  • Amitriptyline Lechiva;
  • Amitriptyline Nycomed;
  • Amitriptyline-AKOS;
  • Amitriptyline-Grindeks;
  • Amitriptyline-LENS;
  • Amitriptyline-Ferein;
  • Amitriptyline hydrochloride;
  • Apo-Amitriptyline;
  • Vero-Amitriptyline;
  • Saroten retard;
  • Triptysole;
  • Elivel.

Similar medicines:

Other medicines:

Reviews (45):
Guests
Agrippina
Acquired with Amitriptyline relatively recently. There was a time when the doctor prescribed this medicine for depression. I started taking with 1/3 of the pill, gradually brought up to take the whole. Took it at night. Anxiety and fears did not go away immediately. As well as it is written in the instruction, I felt better somewhere in 18-20 days. But the side effects were almost immediately. His mouth smacked and his tongue darkened. I had no drowsiness.

Pleases the affordable price of Amitriptyline, since I had to take it for about six months. But still there are many side effects. The effect of addiction was not. If in the future I need to drink antidepressants, then I will ask that they write out another medicine.
Guests
Irina
I happened 2 days ago to get acquainted with the effect of this drug. I was administered it in a drip in parallel with trental and euphyllinum as a complex therapy for the treatment of lumbar osteochondrosis. The state is difficult to describe. 2 days could not get out of bed because of strong dizziness, noise in the ears. There were pressing pains in the region of the heart and pains in the stomach. The pressure decreased, there was an arrhythmia (pulse jumped from 50 to 100 beats per minute).On the second day, plus everything else, there was shortness of breath, pressing pains in the chest, a rash appeared on my face. The upper limbs and the lower part of the face were numb. Dissipation of consciousness, memory impairment, speech fuzziness ... In general, the state is depressing. I thought that I would not live to see a doctor again.
Guests
Sergeeva Raisa
I longly took anaprilin 10 mg + anaprilin 10 mg after treatment of sympathoadrenal crises. I was prescribed a neurologist. It helped. But after 20 years, I am now 60, began to suffer from insomnia and again the same dosage began to help fall asleep. Side effects do not feel, perhaps because a small dose. But other drugs do not help me. I do not know how long I can use these drugs. Advise.
Administrators
admin
Sergeeva Raisa, I so understand Anaprilin + Amitriptyline the doctor has appointed or nominated to you, and not as you have written. If I have written everything correctly, then you can take this drug for a long time, the more the instruction allows. The main thing is to allow your body and your stomach (this drug has a negative in terms of the gastrointestinal tract).

About a sleeplessness it is possible to consult at the doctor as there are much softer preparations for treatment of the given problem. Although if you tried them and did not help, it is quite possible that it will be impossible to pick them up now.
Guests
Antonina
A month ago she was in the hospital and the doctor prescribed Amitriptyline for insomnia. The tablets were white in color and divided into halves. I fell asleep very well. I liked it and went out of the hospital and hurried to get it in the pharmacy. But the tablets turned yellow. Production of "Zentiva" of the Slovak Republic. After taking the pill, sleep did not happen. And now the second week I accept and do not sleep. Noises in the ears, headache. Decided not to take anymore.
Guests
Galina
I was prescribed this medicine by a doctor, during a period of depression related to troubles at work. When I drank the medicine for the first time, I fell asleep almost all day, on the second day the condition was just drowsy (for work is unacceptable), but on the third day I already went to work with a clear mind, calm, confident in myself, doing my job well.She drank this medicine for a month, then reduced the dosage and stopped altogether. I consider this medicine very effective.
Guests
Alexandra
I have a diabetic polyneuropathy. I take amitriptyline at night for 15 years. I did not sleep, only sleeping pills helped at the beginning, then did not help. Now I fall asleep with amitriptyline 1 tab.
Guests
tais
I was given a stress in the hospital. After reception slept 12 hours and it was difficult to wake up in the morning. Then she noticed that her vision was spreading. I think it's better on herbs, something natural to take ...
Guests
Alexandra
I take amitriptyline for 2 years with interruptions. I have a diagnosis of diabetic neuropathy since 2001. I started to treat in 11, I did not sleep at all, I was disturbed by the pains of the feet and hands. Doctors up to 11 g practically did not treat. The diagnosis was osteochondrosis, I suffered so many years, but now the pains are stronger, amitriptyline helps out, but it is not always of good quality.
Guests
Sven
There is no difference, even a Slovak, though African, active substance is one and the same!
Visitors
Irrina
Hello! Dear doctors, tell me, can a single dose of amitriptyline cause a sharp increase in appetite? I was prescribed to drink it for a long time (problems with the spine, pain, insomnia) and I would not like to eat a dozen kilograms and completely kill my spine. The effect was obvious and very bright. Therefore, I think, until you answer me, I will refrain from further taking this drug. The annotation on your site says "a decrease in appetite." But, perhaps, I have a paradox? Were there already such cases? What am I supposed to do?
Administrators
admin
IrrinaA sharp increase in appetite can also be caused by stress from taking a new drug. I think the second and even third time Amitriptyline you take, according to the prescribed scheme of treatment, still have to accurately determine what the reason for the pill. If the medicine is to blame for increased appetite, then it is necessary with the attending physician to decide whether it is possible to cure your back with other medications or not and what is more important is the appetite and accompanying problems with excess weight or back.You have not indicated the diagnosis, so let's proceed from the indispensability of Amitriptyline.
Guests
Lyudmila
The condition was terrible. I will not describe. Wine is an early untreated menopause and in time not revealed a disease of the thyroid gland. Children did not know where to drag me, to which doctors, the ambulance did not want to leave. They advised me to drink Corvalol in the tube. What is Corvalol ?! I was sitting in a forced position in the armchair (I was ill awfully sore) I did not sleep, I did not eat, I could drink only in a second from pain. One neurologist suggested: You have a climacteric neurosis and advised a psychotherapist. Saw Amitriptyline long. The cunning psychotherapist did not really explain what to drink according to the scheme and for a long time! I wanted more patients to see paid psychotherapy sessions. I drank, it became better and left! Everything resumed. Drink strictly according to the scheme and at the end of the course to reduce gradually. I drank about 2 years. You can and for life. Those side-lines are NOTHING in comparison, what happened to me! Before, I did not understand: how can people do away with life ?! Now understand!
Guests
Dmitrieva Oksana
Has laid down in hospital with VSD with panic attacks, on 3 day of treatment to me to anaprilinu 20 have added amitriptyline. Half in the morning, half before lunch on the second day morning, afternoon half, at night the whole, the third day morning, noon, afternoon half of the night the whole, I did not drink for the fourth day in the morning, after lunch, half and whole night, the fifth half day in the morning at 10.00 already done a hundred gram IV with amitriptyline, I felt dizzy, dry throat and tongue, then drank another half to 15.00 and 21.40 still half. I could not sleep for a long time, by the hour of the night my tonsils and throat were dry, there was panic. On the fifth day I realized that something was not right, I read the annotation and stopped drinking them on the fifth day.
Guests
orina
Daughters dripped amitriptyline 2 weeks from depression. Now her condition is worse than it was. She does not recognize anyone. Became a vegetable.
Guests
Ivan
Recently have registered Amitriptyline from a headache - the central nervous system has collapsed + a long depression. Works - yes disguises pain, but does not heal. A year ago, I was cured by acupuncture + manual therapy, but has violated the prohibition and again began to smoke a little, drink coffee in large quantities - that is now being treated again =) And not cheap procedure ...
Guests
Tatyana
And amitriptilin helped me to recover from prolonged depression. No special side effects were observed. The truth has increased activity, and even what. I always wanted to do something. Work, do lots of things to remake. At least with accuracy I can say that from depression it helps one hundred percent. Sometimes there was dry mouth, but insignificant. I drank almost a year. I left it gradually. Delilah tablet in the beginning for 2 admission, then for 4. Month for the three dose came to naught. All of health!
Guests
Irina
Amitriptyline is an old, but very good drug. The main thing is to start with one-fourth at night, and then gradually add and the mood will be excellent.
Guests
Lera
The drug was prescribed in the hospital, there was an anxiety-depressive disorder. She continued to drink after discharge for 2-3 months, but she did not feel any effect. I stopped drinking and after 3 days I felt better. The doctor said that there is a cancellation effect - on the cancellation there is an improvement. Now again I feel bad, I started to drink again.Which is good: I went to the toilet every night at least 4 times, and now only once. But in the first days there was a strange state, when you do not feel the border between sleeping and waking, it seems, you do not sleep, then you realize that you have a dream. On the mood while no effect I do not feel. I will continue to drink.
Guests
manshuk
I had a severe depression after losing my sister and plus everyday problems. For a long time I could not come to my senses, I was treated for 2 years by different neurologists, the condition did not change, I quit my job. Then through acquaintances I went to a therapist, he prescribed amitriptyline together with other medications, I felt better after 2 days. I sleep well amitriptyline I take 1 TB at night. I went to the third month, until I am afraid to cancel it. The doctor said it was too early.
Guests
Maia Kuzmina
Very satisfied with the drug. I accept 1 tab. at 18.00. She began to sleep normally, fears and inner shivers passed. Now I feel the same. Confident. Calm. It ceased to enrage everything. And tearfulness, confusion passed. Very satisfied. I feel like a full-fledged person. In all.
Guests
Natalie 1977
I received these pills from a nurse in a hospital where my husband was treated. He had oncology. He was given one tablet a day when he was sitting on promedol and the pain was unbearable. Whether this medicine helped him or not - I can not say for sure, but the state of anxiety became less obvious. My husband was always afraid when the action of promedolum passed, and the pain would begin.
My husband, unfortunately, died and on the day of the funeral I drank one tablet of this medicine. At the burial service and at the cemetery behaved more or less restrained. And after arriving home, she chopped off and slept for about 5 hours. I did not take this medication any more, but that day he helped me.
Guests
Tatyana
I have been experiencing anxiety for a long time, but I periodically fall into a state of depression. Accidentally learned about the drug, I drank at night only one twice. At night I began to sleep, wake up in the morning to go to the toilet. In the morning, a slight intoxication, but quickly passes. I'm going to drink half a couple more weeks. And there I'll take myself in hand, load myself with work and God will! Side effects did not appear.And as for insomnia, I will give advice that I heard from a psychiatrist. If you are 50-60 years old, then treat with understanding. This is your body is awake before finally falling asleep. I have not been bothering with insomnia for a long time, although I work. But I am surprised by unemployed pensioners who complain of insomnia, they do not go to work, sleep, whenever you want, you will get your portion of sleep at any time.
Guests
Sergey01
I suffer from somatoform dysfunction of the autonomic nervous system. After treatment and positive results I decided to additionally examine the gastrointestinal tract, because there were problems with liquid stool and gas formation. The doctor the therapist, immediately upon admission, appointed me amitriptyline. I did not know about this, give pills - I drink them. Thought some intestinal ... Anxiety began to be beaten when in 5 days it began to ring wildly in the ears and the head buzzing like a transformer box. Having found out, than me treat and from what, I was in bewilderment and wildly upset. I tried to combat self-training with different pills and methods and found the optimal combination for myself in the form of a contrast shower, massage and some psychological exercises.I was left wildly disappointed by the therapist who decided to treat me to God knows what, and even in that area where she does not understand much. Instead of tablets for the intestines, I was eating this rubbish, which has just a huge heap of side effects. In short - do not drink this stuff.
Hello. My daughters prescribed amitriptyline from nocturnal enuresis. When I went to the pharmacy, they told me "Are you going to make a fool out of a child?" We prescribed this medicine as a neurologist for children. Diagnosis of neurosis-like enuresis. Drink at night for 1 tab. child 9 years. She has already drunk a month and has not become a fool, but now I do not know what to do!
Administrators
admin
Elena VedorovnaThe fool is the one who stands at the counter in a white robe and poses as a doctor, not being that way. In terms of prescription, Amitriptyline can be used in children from the age of 6, including treatment of nocturnal enuresis. Especially your child has been taking the drug for a month now and has not become anyone like that. On the diagnosis of the issue of the appointment is justified, I want to believe will help.Pharmacists are not those specialists who are allowed to get into the treatment of patients, they were not taught this training base in institutes and universities.
Guests
GALINA ,,
I read all the reviews and now I'm afraid to take the drug wink
Guests
Asia_04_04
I was prescribed a narcologist. I'm coded for alcohol addiction. But, after I transferred 4 operations in a row to the nose. After a general anesthesia, pimple, nervousness, insomnia went. In general, the narcologist advised this drug. From one pill, I sleep for two days. I can not straight awake ... Dryness in the mouth and disorientation. And in general, nothing. Especially me now rescues, in the period when has stopped to smoke.
Guests
Tatyana
Anxiety disappeared, but every night she dreamed.
Guests
Rav
My mom has been drinking this drug for over a month. The condition is weakness, fatigue. The doctor said you should drink a year, one pill at night drinks.
Guests
AMINA
My pressure rises sharply.After examination, the neuropathologist said that it was all nerves and she prescribed amitriptyline 25 mg.
Guests
Sergey123
At work there are days when everything is on your nerves and "you want to kill." The first time helped one pill, the second with two felled. In a week, even with three tablets of the effect was no more.
Guests
Irina
The drug is not bad. Relieves pain with polyneuropathy, relieves anxiety, improves sleep, etc. But ... Take it carefully, starting with a very small dose, gradually adding up to the desired effect. The drawback is that there are many side effects. I had terrible bitterness in my mouth, dryness and pain in the mammary glands. So I had to cancel the drug. What to replace do not know, severe pain in the legs and hands.
Guests
Irina
Was on day time inpatient treatment for an intervertebral hernia. Have appointed amitriptyline immediately on the whole tablet 3 times a day. I felt terribly - I slept on the move, could not sit behind the wheel, lost orientation, walked like a zombie. I did not listen to the doctor and began to drink one pill at night.She felt relief, a good calm sleep, after which she got up rested. Now I drink sometimes at night as sleeping pills. It helps.
Guests
Asya
I had a prolonged depression and agoraphobia. To me have appointed or nominated amitriptyline in \ m 10 days, then escitalopram and trunk. I am treated for 3,5 years, now the condition has sharply worsened, can again pierce amitriptyline 10 days?
Administrators
admin
AsyaIf 3,5 years have elapsed since the previous course of treatment with Amitriptyline, re-use of the drug is permissible. Only to the full-time doctor all the same it is necessary to descend or go, even behind the prescription.
Guests
Olga
Hello. Here I am from nerves I can not eat normally. In general, almost do not eat. Already the skeleton is similar and this despite the fact that I have two children. Have appointed or nominated to me amitriptyline 25 for the night. Immediately after the first pill I began to eat very well, although the instructions say that the drug should lower the appetite.
Guests
Love
I've been drinking Amitriptyline nicomed for more than a year and a half. The condition improved. Has recovered, and there was 35 kg, now 72 at body height 71.I was panic attacked, shaking, fear constantly lived with me, could not sleep at night, I walked on the street. I drink 1 tablet at 14 00.
Guests
Tatyana
In 2016, I went to a psychiatric hospital where I was not even told a diagnosis. They gave amitriptyline. I do not know the dose. As a sedative it did not help me, but it became easier for me in my main disease - rheumatoid arthritis. One day I woke up in the morning and felt that my legs were not aching and I could move freely. What is this effect of this drug I do not know, but I felt better. After the hospital, the drug was not taken and the pain returned. Now I decided to try myself to take 1 tablet at night.
Guests
Meiri
This drug was taken by the mother 20 years ago and he helped her very much, she got rid of fear, anxiety and insomnia, but now she has the same problems and we want to start taking it again.
Guests
Love
Amitriptyline Nycomed, a question to the doctor, is there any addiction to it?
Administrators
admin
LoveThe addiction to Amitriptyline in the instruction says nothing. The withdrawal syndrome with a sudden discontinuation of the medication is possible.
Guests
Love,
Amitriptyline Nycomed appointed me a rheumatologist to remove the pain syndrome. I took 8 months 25 mg at night. The pain syndrome has left, began to sleep, began to dream. Fear and anxiety went away. I became cheerful. A congestion: dryness in a mouth, a distraction of attention, constipations at me a problem with GASTROINTESTINAL TRACT is better, than to cry, be irritated, the pain became tolerant. The nervous system managed to become.
Guests
Tatyana
To me have registered this preparation in the afternoon and for the night. When I drank during the day - I just got demolished, I fell asleep in the chair in the kitchen, it's good that it was a day off and I did not drive. After that, I did not drink this drug any more and started to warn everyone.
Guests
Olga
They were tormented with enuresis at the son of 12 years. We could not go to the camp or hike. And here one neurologist has appointed or nominated Amitriptyline on 1 tab. at night. Within a month we forgot about enuresis.Did not notice the pills. It's just happiness, to sleep without diapers. Only take a dose with a doctor, by age.

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