Logest - instructions for use, analogs, testimonials and release forms (tablets 20 + 75) of a contraceptive for contraception in women, including during pregnancy and lactation. Cancellation and side effects after taking
In this article, you can read the instructions for using the contraceptive Logest. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Logest in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Logest's analogs in the presence of existing structural analogues. Use for contraception in women, including during pregnancy and lactation. Cancellation and side effects after taking the drug.
Logest - monophasic combined gestagen-estrogen contraceptive drug. Oppresses the secretion of gonadotropic hormones of the pituitary gland, inhibits the maturation of follicles and prevents the process of ovulation. Increases the viscosity of cervical mucus, which makes it difficult to penetrate the sperm into the uterus.
Against the background of the use of the drug, the menstrual cycle becomes more regular, less painful menstruation is observed, the intensity of menstrual flow decreases, which reduces the risk of iron deficiency anemia.
Composition
Ethinyl estradiol + Gestodene + auxiliary substances.
Pharmacokinetics
Gestoden
After taking the tablets inside Gestodene quickly and completely absorbed from the digestive tract. Gestodene, mainly (about 69%), binds to globulin (GSPC - globulin, binding sex steroids). With the daily administration of Logest, the accumulation of Gestodene in the serum is observed, with the average level of Gestodene in the second half of the cycle (after 2 weeks of administration) approximately 4 times higher than at the beginning of the drug. Gestodene is excreted from the body only in the form of metabolites. Metabolites are excreted by the kidneys and through the intestine in a ratio of 6: 4.
Ethinylestradiol
After taking the tablets inside, ethinyl estradiol is quickly and completely absorbed from the digestive tract. About 0.02% of the daily dose of ethinylestradiol is excreted in breast milk. Ethinyl estradiol is biotransformed in the body. It is excreted in the form of metabolites with urine and bile in a ratio of 4: 6.
Indications
- contraception.
Forms of release
Tablets coated with a coating of 20 μg + 75 μg.
Instructions for use and reception scheme
The drug is taken 1 tablet a day for 21 days at the same time.
Logest's reception starts on the 1st day of the cycle, using tablets from the cell marked with the corresponding day of the week. After completing the intake of all 21 tablets from the calendar package, a 7-day break in taking the drug follows, during which menstrual bleeding occurs. Each next package should be taken after a 7-day break in taking the drug (regardless of whether menstrual bleeding has stopped by this time or not).
When switching from combined oral contraceptives, it is preferable to start taking Logest the next day after taking the last active tablet from the previous package,but not in any case not later than the next day after the usual 7-day break in admission (for preparations containing 21 tablets) or after taking the last inactive tablet (for preparations containing 28 tablets in the package).
If a woman used contraceptives containing only gestagen ("mini-drank"), then you can switch to Logest any day (without a break).
When using injectable forms of contraceptives containing only progestogen, Logestus is taken from the day the next injection is to be taken.
When moving from implants - the day it is removed. In all cases, it is necessary to use an additional barrier method of contraception during the first 7 days of taking the tablets.
After an abortion in the first trimester of pregnancy, a woman can start taking the drug immediately. In this case, the woman does not need additional contraceptive measures.
After childbirth or abortion in the 2nd trimester of pregnancy, the drug should be taken on the 21-28th day. If the reception is started later, then it is necessary to use an additional barrier method of contraception during the first 7 days of taking the tablets. If a woman has had a sex life between childbirth or abortion andthe beginning of taking Logesta, then first you should exclude pregnancy or you must wait for the first menstruation.
If the patient for any reason did not take the pill at the usual time and after less than 12 hours after the prescribed time, the contraceptive effect of the drug is still ongoing and the missed tablet should be taken as soon as possible. The next tablet should be taken at the set time. Thus, taking 2 tablets per day is possible. In the event that more than 12 hours have elapsed since the prescribed time of admission, the missed tablet should be immediately taken. Then continue the course as usual. It is necessary to use additional barrier methods of contraception in the next 7 days, since in this case the contraceptive effect of the drug is weakened. If less than 7 tablets are left in the package, taking the product from the next package begins without interruption.
Side effect
- nausea, vomiting;
- intermenstrual bleeding (during the first few months of admission);
- changes in vaginal secretion;
- feeling of tension and enlargement of the mammary glands;
- changes in body weight;
- changes in libido;
- decreased mood;
- headache;
- migraine;
- poor tolerance of contact lenses;
- fluid retention in the body;
- allergic reactions.
Contraindications
- presence of thromboses (venous and arterial) at present or in the anamnesis (for example, deep vein thrombosis of the lower limbs, thromboembolism of the pulmonary artery branches, myocardial infarction, cerebrovascular disorders);
- presence at present or in anamnesis of conditions preceding thrombosis (eg, transient ischemic attacks, angina pectoris);
- diabetes mellitus with vascular complications;
- presence of severe or multiple risk factors for venous or arterial thrombosis;
- the presence at present or in the history of jaundice or severe forms of liver disease (until liver tests are normal);
- the presence at present or in the history of liver tumors (benign or malignant);
- Migraine with focal neurologic symptoms (including in history);
- Pancreatitis with severe hypertriglyceridemia (including in the anamnesis);
- identified hormone-dependent malignant diseases of the genitals or mammary glands (including in the anamnesis);
- vaginal bleeding of unknown origin;
- pregnancy or suspected of it;
- lactation;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
Logest is contraindicated for use in pregnancy.
If you need to use the drug during lactation, you should decide whether to stop breastfeeding. The active substances that make up the drug are excreted in small amounts with breast milk.
special instructions
Before starting the drug, a woman should undergo a thorough general medical and gynecological examination (including breast examination and cytological examination of cervical mucus), exclude pregnancy and violations of blood coagulation.
With caution appoint the drug to patients with diabetes mellitus, hypertension, varicose veins, impaired renal function, uterine myomas, otosclerosis, migraine, multiple sclerosis, epilepsy, porphyria, systemic lupus erythematosus, excessive body weight, fibrocystic mastopathy, severe depression in anamnesis; if there is a family history of thromboembolism, chronic heart failure, strokes, breast cancer.
The relative risk of developing arterial thrombosis increases with combined use of combined hormonal contraceptives with such risk factors as age over 35 years and smoking. In this regard, smokers over 35 years of age are recommended to quit smoking if they intend to take Logest for contraception.
The risk of thrombosis is also increased in the presence of a burdened family history, obesity, dyslipoproteinemia, arterial hypertension, heart valve diseases, atrial fibrillation.
Reception of the drug is stopped 6 weeks before the scheduled surgery, as well as if necessary for prolonged immobilization and renewed 2 weeks after the end of immobilization due to an increased risk of thrombosis.
If pain occurs in the lower limbs along the veins, swelling of the extremities, acute pain or a feeling of constriction or heaviness in the chest, sudden dyspnea, it is necessary to cancel the drug and conduct tests to identify possible thrombosis or thromboembolism.
When using Logest, it should be borne in mind that the usual course of the menstrual cycle, the rectal temperature and the properties of the cervical mucus can change with the hormonal contraceptive intake.
If there is a permanent skin itch, severe pain in the lower abdomen, severe headaches and migraines, severe depression, a significant increase in blood pressure, frequent seizures, sudden changes in sight, hearing or speech, you should cancel the drug and conduct an additional examination.
Intermenstrual bloody discharge may occur during the first few months of admission and cease after adaptation of the organism to Logesta. If you reoccurrence of such secretions or increase their intensity, you should conduct an additional examination of the patient.
If there is no menstrual bleeding during the 7-day break in taking the pills, it is necessary, without renewing the drug, to conduct the examination of the patient.
When vomiting, diarrhea within 3-4 hours after taking the drug, its contraceptive effect may be reduced. In this case, you should continue to receive Logest and simultaneously use additional non-hormonal methods of contraception.
In case of concomitant use of Logesta and rifampicin, the contraceptive effect of Logestus decreases, therefore additional methods of contraception should be used within 4 weeks after the end of the antibiotic intake.
Women who take short courses of medications that affect the effectiveness of the drug Logest should temporarily apply the barrier method of contraception while taking the appropriate drugs and within 7 days after their withdrawal.
Patients who develop chloasma should avoid exposure to sunlight during the period of application.
Drug Interactions
With simultaneous use of rifampicin, ampicillin, tetracyclines, griseofulvin, non-steroidal anti-inflammatory drugs, phenytoin, phenobarbital, Carbamazepine lower the efficacy of Logest.
Analogues of the drug Logest
Structural analogs for the active substance:
- Lindineth 20;
- Lyndyneth 30;
- Mirell;
- Femoden.
Similar medicines:
Other medicines:
- Triderm - instructions for use, analogs, reviews and release forms (ointment and cream for external use) drugs for treating lichen, neurodermatitis, eczema and psoriasis in adults, children and pregnancy
- Decaris - instructions for use, analogs, reviews and release forms (tablets of 50 mg and 150 mg) of the drug for the treatment of helminthiases (ascariasis, enterobiasis and other worms) in adults, children and in pregnancy based on levamisole
- Lincomycin - instructions for use, reviews, analogs and forms of release (capsules or tablets 250 mg hydrochloride, injections in injections, ointment) of a medicament for the treatment of abscess, endocarditis in adults, children and pregnancy