Triderm - instructions for use, analogs, reviews and release forms (ointment and cream for external use) drugs for treating lichen, neurodermatitis, eczema and psoriasis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Triderm. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Triderm in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Triederma in the presence of existing structural analogues. Use for the treatment of dermatitis, neurodermatitis, eczema and psoriasis in adults, children, as well as during pregnancy and lactation.

Triderm - a combined preparation for external use.

Ointment Triderm combines antiphlogistic, antipruritic, antiallergic and antiexudative effect of glucocorticosteroid (GCS) of Betamethasone dipropionate with antifungal activity of Clotrimazole and broad antibacterial action of Gentamicin sulfate.

Cream Triderm combines antiphlogistic, antipruritic, antiallergic and antiexudative effect of betamethasone dipropionate with antifungal activity of clotrimazole and broad antibacterial action of gentamycin sulfate.

Clotrimazole has an antifungal effect due to a disruption in the synthesis of ergosterol, which is an integral part of the fungal cell membrane. It is active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, Malassezia furtur (Pityrosporum obiculare).

Gentamicin is a broad-spectrum antibiotic from the aminoglycoside group. It is bactericidal and provides highly effective local treatment of primary and secondary bacterial skin infections. It is active against gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae; gram-positive bacteria: Streptococcus spp.(sensitive strains of beta-and alpha-hemolytic streptococcus group A), Staphylococcus aureus (coagulase-positive, coagulase-negative and some strains producing penicillinase).

Composition

Betamethasone dipropionate + Clotrimazole + Gentamicin (in the form of sulfate) + auxiliary substances.

Indications

• Dermatoses complicated by infections caused by drug-susceptible pathogens, or suspected of such infections, including simple and allergic dermatitis, atopic dermatitis (including diffuse neurodermatitis), limited neurodermatitis, eczema, dermatomycosis (dermatophytin, candidiasis, multicolored lichen), especially when localized in the groin and large folds of the skin;
• simple chronic lichen (limited neurodermatitis).

Forms of release

Ointment for external use (15 g).

Cream for external use (15 g and 30 g).

Instructions for use and how to use them

Ointment

Ointment Triderm should be applied a thin layer on the entire affected surface of the skin and surrounding tissue 2 times a day - in the morning and at night. To ensure the effectiveness of treatment Tridentum ointment should be used regularly.The duration of therapy depends on the size and localization of the lesion, as well as, the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may serve as a reason for specifying the diagnosis.

Cream

Cream Triderm should be applied a thin layer on the entire affected surface of the skin and surrounding tissue twice a day - in the morning and at night. To ensure the effectiveness of treatment, the Tridermine cream should be used regularly. The duration of therapy depends on the size and location of the lesion, as well as, the patient's response.

If clinical improvement does not occur after 3-4 weeks of treatment, this may serve as a reason for specifying the diagnosis.

Side effect

• burning sensation;
• erythema;
• exudation;
• maceration of the skin;
• violation of pigmentation (hypopigmentation);
• itching;
• dry skin;
• hypertrichosis;
• acne (pimples);
• development of secondary infection;
• skin atrophy;
• stria;
• prickly heat;
• the appearance of blisters;
• peeling;
• local edema.

Contraindications

• lupus;
• cutaneous manifestations of syphilis;
• chickenpox;
• herpes simplex;
• dermal post-vaccination reactions;
• open wounds;
• children's age (up to 2 years);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The use of Triderm during pregnancy is possible only if the intended benefit to the mother exceeds the potential risk to the fetus.

It is not known whether the components of the drug are excreted in breast milk. Therefore, when appointing Triderma during lactation, it is necessary to resolve the issue of stopping breastfeeding.

special instructions

Ointment Triderm is not intended for use in ophthalmology.

Prolonged local use of antibiotics can sometimes lead to an increase in resistant microflora. In this case, as well as with the development of irritation, sensitization or superinfection in the treatment of Triderm ointment, treatment should be discontinued and appropriate therapy prescribed. There were cross-allergic reactions with aminoglycolytic antibiotics.

Any side effects that occur with the use of systemic glucocorticosteroids, including suppression of adrenal cortex function, can also be noted with topical application of GCS, especially in children.

Systemic absorption of GCS or gentamicin for topical application will be higher,if the radiation will be carried out on large areas of the skin or with the use of occlusive dressings, especially with prolonged treatment or in violation of the integrity of the skin. It is necessary to avoid applying gentamicin to open wounds and damaged skin. Otherwise, there may be side effects, characteristic of gentamicin in its systemic application. Appropriate precautions should be taken in such cases, especially when treating children.

With prolonged use of the drug, it is recommended to cancel it gradually.

Use in Pediatrics

Children are prescribed the drug only under strict indications and under medical supervision, since it is possible to develop systemic side effects associated with betamethasone. When triderma, as well as many other topical preparations based on GCS, on extensive surfaces and / or with occlusive dressing can suppress the function of the hypothalamic-pituitary-adrenal system, a decrease in the excretion of growth hormone, as well as an increase in intracranial pressure, can be observed.

Drug Interactions

Due to low systemic absorption, interaction with other drugs has not been observed.

Analogues of the drug Triderm

Structural analogs for the active substance:

• Acriderm GK;
• Canison Plus.

Similar medicines:

Other medicines: