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Indapamide - instructions for use, reviews, analogs and formulations (tablets 2.5 mg and 1.5 mg retard, MB and Stade, capsules 2.5 mg Verte), a diuretic for the treatment of arterial hypertension in adults, children and pregnancy

Indapamide - instructions for use, reviews, analogs and formulations (tablets 2.5 mg and 1.5 mg retard, MB and Stade, capsules 2.5 mg Verte), a diuretic for the treatment of arterial hypertension in adults, children and pregnancy

In this article, you can read the instructions for using the drug Indapamide. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of diuretic Indapamide in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Indapamide in the presence of existing structural analogs. Use for the treatment of hypertension in adults, children, as well as in pregnancy and lactation.How long it takes to take the drug.

 

Indapamide - an antihypertensive drug, a thiazide-like diuretic with a moderate in strength and long duration of action, a benzamide derivative. Has moderate saluretic and diuretic effects, which are associated with blockade of reabsorption of sodium, chlorine, hydrogen ions, and to a lesser extent potassium ions in the proximal tubules and cortical segment of the nephron distal tubule. The vasodilator effects and the reduction of the overall peripheral vascular resistance are based on the following mechanisms: a decrease in the reactivity of the vascular wall to norepinephrine and angiotensin 2; an increase in the synthesis of prostaglandins with vasodilating activity; oppression of calcium current in the smooth-muscle walls of blood vessels.

 

Reduces the tone of the smooth muscles of the arteries, reduces the overall peripheral resistance of the vessels. Helps reduce hypertrophy of the left ventricle of the heart. In therapeutic doses does not affect lipid and carbohydrate metabolism (including in patients with concomitant diabetes mellitus).

 

Antihypertensive effect develops at the end of the first / beginning of the second week with a constant intake of the drug and persists for 24 hours against a background of a single dose.

 

Pharmacokinetics

 

After oral administration, it is quickly and completely absorbed from the digestive tract; bioavailability is high (93%). Eating somewhat slows the rate of absorption, but does not affect the amount of absorbed substance. Has a high volume of distribution, passes through the histohematological barriers (including placental), penetrates into breast milk. Metabolised in the liver. The kidneys excrete 60-80% in the form of metabolites (in unchanged form, about 5% is excreted), through the intestine - 20%. In patients with renal insufficiency, pharmacokinetics does not change. Do not cumulate.

 

Indications

  • arterial hypertension.

 

Forms of release

 

Tablets, film-coated 2.5 mg.

 

Tablets coated with 2.5 mg of Stade.

 

Modified release tablets coated with 1.5 mg Indapamide MB.

 

Tablets of prolonged action, coated with 1.5 mg retard.

 

Capsules 2.5 mg Verte.

 

Instructions for use and dosing regimen

 

Tablets are taken orally, without chewing. The daily dose of the drug is 1 tablet (2.5 mg) per day (in the morning). If after 4-8 weeks of treatment the desired therapeutic effect is not achieved, the dose of the drug should not be increased (an increase in the risk of side effects without strengthening the anti-neuronrhagic effect).Instead, it is recommended that another antihypertensive drug that is not a diuretic be included in the drug regimen.

 

In cases where treatment should start with the taking of two drugs, the dose of Indapamide remains 2.5 mg in the morning once a day.

 

Retard

 

Inside, not liquid, squeezed enough liquid, regardless of food intake, mainly in the morning hours at a dose of 1.5 mg (1 tablet) per day.

 

If the desired therapeutic effect is not achieved after 4-8 weeks of treatment, the dose of the drug should not be increased (the risk of side effects increases without increasing the antihypertensive effect). Instead, it is recommended that another antihypertensive drug that is not a diuretic be included in the drug regimen. In cases where treatment should begin with the taking of two drugs, the dose of Indapamide retard remains equal to 1.5 mg in the morning once a day.

 

In elderly patients, plasma concentration of creatinine should be monitored taking into account age, body weight and sex, the drug can be used in elderly patients with normal or slightly impaired renal function.

 

Side effect

  • nausea, vomiting;
  • anorexia;
  • dry mouth;
  • gastralgia;
  • diarrhea;
  • constipation;
  • asthenia;
  • nervousness;
  • headache;
  • dizziness;
  • drowsiness;
  • insomnia;
  • depression;
  • increased fatigue;
  • general weakness;
  • malaise;
  • muscle spasm;
  • irritability;
  • conjunctivitis;
  • impaired vision;
  • cough;
  • pharyngitis;
  • sinusitis;
  • rhinitis;
  • orthostatic hypotension;
  • arrhythmia;
  • palpitation;
  • nocturia;
  • polyuria;
  • rash;
  • hives;
  • itching;
  • hemorrhagic vasculitis;
  • Hyperglycemia, hypokalemia, hypochloraemia, hyponatremia, hypercalcemia;
  • influenza-like syndrome;
  • pain in the chest;
  • backache;
  • decreased potency;
  • decreased libido;
  • rhinorrhea;
  • sweating;
  • decreased body weight;
  • tingling in the extremities.

 

Contraindications

  • anuria;
  • hypokalemia;
  • expressed hepatic (including with encephalopathy) and / or renal failure;
  • pregnancy;
  • lactation period;
  • age under 18 years (effectiveness and safety not established);
  • simultaneous reception of drugs that extend the QT interval;
  • hypersensitivity to the drug and other sulfonamide derivatives.

 

Application in pregnancy and lactation

 

Contraindicated in pregnancy and lactation.

 

special instructions

 

In patients taking cardiac glycosides, laxatives, against the background of hyperaldosteronism, as well as in the elderly, regular monitoring of the content of potassium and creatinine ions is shown.

 

On the background of taking indapamide, the concentration of potassium, sodium, magnesium ions in the blood plasma (electrolyte disturbances may develop), pH, glucose concentration, uric acid and residual Nitrogen should be systematically monitored.

 

The most thorough control is shown in patients with cirrhosis of the liver (especially with edema or ascites - the risk of metabolic alkalosis, increasing manifestations of hepatic encephalopathy), coronary heart disease, chronic heart failure, and also in the elderly. Patients with an increased QT interval on an electrocardiogram (congenital or developing against a background of a pathological process) also belong to the high-risk group.

 

The first measurement of the potassium concentration in the blood should be performed during the first week of treatment.

 

For a diuretic and antihypertensive effect, the drug must be taken for life, in the absence of side effects and contraindications to admission.

 

Hypercalcemia on the background of taking indapamide may be a consequence of previously undiagnosed hyperparathyroidism.

 

In patients with diabetes mellitus, it is extremely important to control the level of glucose in the blood, especially in the presence of hypokapaemia.

 

Significant dehydration can lead to the development of acute renal failure (reduced glomerular filtration). Patients must compensate for the loss of water and at the beginning of treatment carefully monitor the kidney function.

 

Indapamide can give a positive result in the conduct of doping control.

 

Patients with hypertension and hyponatremia (due to taking diuretics) need to stop taking diuretics 3 days before the start of taking ACE inhibitors (if necessary, diuretics can be taken a little later) or they are given initial low doses of ACE inhibitors.

 

Derivatives of sulfonamides can aggravate the course of systemic lupus erythematosus (it should be borne in mind when administering indapamide).

 

Impact on the ability to drive vehicles and manage mechanisms

 

During the treatment period, care must be taken when driving vehicles and occupationsother potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions.

 

Drug Interactions

 

Saluretics, cardiac glycosides, gluco- and mineralocorticoids, tetracosactide, amphotericin B (intravenously), laxatives increase the risk of hypokalemia.

 

With simultaneous admission with cardiac glycosides, the likelihood of developing digitalis intoxication increases; with preparations of Ca2 - hypercalcemia; with Metformin - may aggravate lactic acidosis.

 

Increases the concentration of lithium ions in the blood plasma (decreased excretion in the urine), lithium has a nephrotoxic effect.

 

Astemizole, Erythromycin intranasally, pentamidine, sultopride, terfenadine, vincamine, antiarrhythmic drugs 1a class (quinidine, disopyramide) and 3 classes (amiodarone, brethylium, sotalol) can lead to the development of torsades de pointes.

 

Non-steroidal anti-inflammatory drugs, glucocorticosteroid agents, tetracosactide, sympathomimetics reduce the hypotensive effect, Baclofen - strengthens.

 

Combination with potassium-sparing diuretics can be effective in some patients, however,while the possibility of developing hypo- or hyperkalemia, especially in patients with diabetes mellitus and renal insufficiency, is not completely excluded.

 

ACE inhibitors increase the risk of arterial hypotension and / or acute renal failure (especially with existing renal artery stenosis).

 

Increases the risk of kidney dysfunction when using iodine-containing contrast media in high doses (dehydration of the body). Before using iodine-containing contrast agents, patients need to restore fluid loss.

 

Imipramine (tricyclic) antidepressants and antipsychotic drugs increase the hypotensive effect and increase the risk of developing orthostatic hypotension.

 

Cyclosporine increases the risk of hypercreatininaemia.

 

Reduces the effect of indirect anticoagulants (coumarin or indanedione derivatives) due to an increase in the concentration of clotting factors as a result of a decrease in the volume of circulating blood and increase in their production by the liver (dosage adjustment may be required).

 

Strengthens the blockade of neuromuscular transmission,developing under the influence of nondepolarizing muscle relaxants.

 

Analogues of the drug Indapamide

 

Structural analogs for the active substance:

  • Acrypamide;
  • Acrypamide retard;
  • Acuter-Sanovel;
  • Arindap;
  • Arifon;
  • Arifon retard;
  • Vero-Indapamide;
  • Indap;
  • Indapamide MB Stade;
  • Indapamide retard;
  • Indapamid Stade;
  • Indapamide-OBL;
  • Indapamid-Verte;
  • Indapamid-Teva;
  • Inder;
  • Inverse;
  • Indians;
  • Indyur;
  • Ionik;
  • Ionik retard;
  • Ipres Long;
  • Lauras SR;
  • Pamid;
  • Ravel SR;
  • Retapres;
  • SR-Indamed;
  • Tenzar.

Similar medicines:

Other medicines:

Reviews (117):
Guests
Artem
Dedovind indapamide helped to reduce high blood pressure, naturally in combination, since before that, both enalapril-lisinopril and eugloco-concoras were tried, all to no avail. One clever doctor prescribed noliprel, there was a sudden decrease in pressure, but I did not pull out such a treatment for finance, so my therapist appointed lisinopril with indapamide (the same noliprel was said, it would only get cheaper for me) and everything settled. In general, with pressure, you need to select drugs individually, including for money, then it will be useful.
Guests
kudryavchenko galina
How long can I take indapamide?
Administrators
admin
kudryavchenko galinaCan be taken indefinitely. The main thing is that there should be no side effects when taking Indapamide, especially those associated with a lack of potassium (which this drug flushes out of the body): fatigue, weakness, decreased muscle tone, etc.
Visitors
galina79614
I take Indapamide 2.5 with Bisoprolol 2.5 in the mornings for about a year. Very satisfied. Is it permissible to take Metformin simultaneously? In the evening I still accept Lorist.
Administrators
admin
galina79614You can take the medicines you indicated together. According to the instruction there should be no negative side effects during joint admission. However, it should be noted that when Metformin is used with diuretics and in particular with Indapamide, a more careful control of blood glucose (sugar) level is necessary, and Metformin dosage adjustment may be increased upwards, as the combined use of this medication with diuretics leads to a decrease in hypoglycemic action of the latter.
Guests
Tatyana
Indapamide, can I use instead of enalapril?
Administrators
admin
Tatyana, In the garden of elder ... Indapamid is a diuretic, Enalapril is an ACE inhibitor. Different drugs, different pharmacological groups. Often designate together. If to reduce the pressure, then start with Enalapril, and then in case of inefficiency or the presence of edema, then immediately, designate Indapamide. Contact your doctor for advice and treatment.
I take indapamide on the recommendation of a doctor in conjunction with amlodipine (morning-evening) for 4 years. Zaimel diagnosis: polyneuropathy of the lower extremities (in the presence of hypoparathyroidism). The neurologist did not offer to choose another scheme for the treatment of hypertension. Is it possible to restore the axons when this scheme is canceled?

--------------------
Administrators
admin
Elena Chistyakova, Your therapy scheme does not in any way concern polyneuropathy.Probably the reason is for something else, because neither Indapamide nor Amlodipine influence the development of this disease and can not provoke it. Maybe the reason in the violation of metabolism, diabetes, a problem with the liver, can thyroid influences the metabolism in the nervous tissue. I would look for a reason in the exchange violation.
Visitors
vereteno13
Side effects on inhibitors have been identified, right up to the Quincke edema. Now the therapist prescribed Noliprel + Amlodipine. The cardiologist was surprised, since Noliprel also contains an inhibitor, and Indapamide was prescribed instead. So, you get two diuretics - is not it a lot? I never had any swelling, the pressure rose to 170 at 110. Can you please, what else can I replace with inhibitors other than diuretics?
Administrators
admin
vereteno13, Amlodipine is not a diuretic - it is a blocker of calcium channels. Therefore, the combination of Amlodipine + Indapamide is good. You can also try. Amlodipine sometimes causes swelling, so take it first with caution, watch for pressure and swelling, especially on the legs.

The group of calcium channel blockers is big in it and Nifedipine, and Lercamen and many other less popular drugs. Still it is possible to try beta-blockers (Atenolol, Bisoprolol and others). In an extreme case, angiotensin 2 receptor antagonists (Valsartan, Losartan and others) can be tried, but they may have cross-sensitivity with ACE inhibitors and the allergy may recur. But any replacement should be agreed with the doctor who sees your medical history and concomitant pathology.

Noliprel is really not worth taking, it contains an ACE inhibitor for which you are allergic.
Guests
Maria Semyonovna
Hello! The doctor has appointed or nominated to drink Indapamid I have noticed, that has grown thin. I do not want to lose weight. How can I be in this case? Thank you.
Administrators
admin
Maria SemyonovnaYou lose weight, because the excess fluid leaves the body, to get rid of which, you probably had a diuretic drug Indapamide. Other questions on what can be replaced or how to cancel a medicine is better to ask your doctor. in the matter of the initial information there.
Guests
Lika
Hello. To me the masseuse advised to drink indapamid that there was an excess liquid. Is it dangerous?
Guests
Lyudmila
Good afternoon! The endocrinologist advised me to take indapamide for a week to reduce excess fluid in the body. I take lodos, and many years ago I had mild urticaria with sulphadimethoxin. Is it possible to take indapamide in this situation? Thank you.
Administrators
admin
Lika, Dangerous as any other drug use by an amateur. The masseuse as follows from a question the doctor is not. And so - the disease or a description of the problem is not indicated, they are not registered themselves, so there is nothing to answer on the merits. Address to the doctor.

Lyudmila, In fact, you are already taking a drug that contains a diuretic - it's Lodose, which contains along with a beta-blocker and a diuretic hydrochlorothiazide. So in your case it is necessary to look at the general condition, the nature of the disease and the tolerability and such combination therapy can only be prescribed by your doctor.

Combining these diuretics can be because they are from the same pharmacological group - thiazide diuretics and their derivatives, only this will lead to an increase in the diuretic effect, as well as possible washing out of microelements from the body. Remotely, your question is not solved, only in person.
Guests
Galina
A good site, because doctors often do not explain the effect of drugs. He helped me to understand the treatment correctly.
Guests
Alla
Hello! I am 44 years old. Twice a year there are exacerbations of hypertensive disease (2 items). Up to 170 / 120. Used to drink Tark - it helped. Now this drug is not available in our pharmacy chains. For a month I've been drinking indapamide. The pressure became more stable. 140/90 or 130/90. True pulse is always 85-90. Advise: continue to drink indapamide or replace it with noliprel? Maybe there's something else to add? Thank you in advance!
Administrators
admin
Alla, You need to see a doctor, because Tarka and Indapamide, as well as Noliprel, are not analogues of the active substance.Yes, these drugs reduce the pressure, but from these groups you can find many other medicines, as they say, choose any. In this case, only a doctor can help, who dynamically observes the patient, knows his medical history and can prescribe a suitable medicine.
Visitors
Frosty
The cardiologist has appointed or nominated indapamid and simultaneously валз and корсаан from a tachycardia. As I understand indapamide is not a potassium-sparing diuretic, and before taking valz from such should be abandoned to restore electrolytes. Means simultaneously it is impossible? Coraxane is also not recommended at the same time as thiazide-like diuretics, like indapamide, I used to take concorre, it lowered my chest pressure and because of bronchitis the cardiologist suggested this regimen, but I'm not sure if she is right?
Administrators
admin
FrostyThe last point of the question did not understand - Indapamid with Concor? Nominal combination. the truth in the issue I saw only a tachycardia, so why the diuretic is necessary to me is unclear.

On the first part of the question.Valls with Indapamid - always please, I do not know where you take this heresy about Wales and diuretics diuretic diuretics, I will say more - it is more dangerous to prescribe potassium-sparing diuretics with Wals. If you are very worried about this issue, you can take courses in large doses Asparkam, Panangin or other donators of potassium, if this is necessary. But Indapamid and Coraxan can really be dangerous, therefore it is better to designate this scheme thoughtfully and to control the level of electrolytes of blood in the process of treatment.

In other respects the treatment is multifaceted, so without the help of a cardiologist, who can clarify the disputable moments live you can not do.
Visitors
Snowing
The cardiologist assigned the following combination to the grandmother: Indapamide 2.5 mg in the morning, Losartan 25 mg + Amlodipine 10 mg in the evening. During the day, Tulip 10 mg, Trombo Ass 100 mg. For a long time, did not treat hypertension, and later an inefficient combination of Concor 5 mg mornings, Captopril 25 mg in the evening. On the first day of the new treatment, the pressure became 130/80, before that, on average, 160 \ 180-70 \ 90, I thought that everything would be fine, but on the second day the pressure dropped 100-110-160, the pulse 100-130.And now I do not know what to do, I do not get to see a doctor within 2-3 weeks. Reduce the dose or something to note? Or maybe this is a temporary reaction to the beginning of treatment?
Administrators
admin
Snowing, Try to reduce the evening dosage of Amlodipine to 5 mg. If the pressure is still kept at low values ​​it will be possible to completely cancel the day after 3 or halve the morning dose of Losartan (instead of the current 25 mg, leave 12.5 mg). Indapamide can be left. After the holidays, always consult a doctor to check that you are doing everything right.
Guests
Galina
Is it possible to take Indapamide only to stabilize the pressure instead of Lorist? Thank you.
Administrators
admin
GalinaSomeone and one Indapamide helps in stabilizing the pressure, although it happens rarely. Talk with your doctor.
Guests
Max
I take enalapril (10 mg) and started taking indapamide (2.5 mg) (as prescribed by the doctor). After two days of taking indapamide, the pressure dropped sharply.Is it possible to take indapamide (2.5 mg) less often than every day, i.e. two days to take, five days of rest?
Administrators
admin
MaxIn the first two weeks after the start of taking antihypertensive drugs, the pressure may fluctuate upward or downward, and after this time period, the values ​​are fixed and the tactics of taking the medications with the attending physician are changed. I would start with a reduction in the dosage of Enalapril.
Guests
Bedenko Tatyana Grigoryevna
The drug to take before meals or after?
Administrators
admin
Bedenko Tatyana Grigoryevna, Indapamide, like any other diuretic is taken on an empty stomach 30 minutes before meals.
Guests
Emma Nikolaevna
I am 84 years old. The diagnosis is CHD. Accepted Concor plus Indapamide plus Aspirin (before bedtime) for a year. The pulse dropped sharply to 45. The cardiologist canceled Concor. Pulse recovered. The pressure is 120/80 - 145/90. Pulse on average 70. The whole year I use the breathing apparatus "Super Health" for 20 minutes daily. I feel good. I'm engaged in Scandinavian walking.
Guests
Eustace
For a long time and regularly I take in the morning Wales. The therapist recommended adding 2.5 mg of indapamide, but on the third day the pressure became 103-110 / 58-62. Can I continue taking Indapamide?
Administrators
admin
EustaceThe question of taking Indadamid in your situation is not obvious. Register and describe in more detail your situation (the medical history, than the doctor motivated the appointment of an additional component of treatment), so that the consultation could take place.
Guests
Alexandra
Hello colleague, my mom 84 years after the stroke appointed losartan and physiotheros. (Before that, my mother had a year on indapamide with very good effect, but given the heat and loss of fluid, the therapist changed the appointment). Since the appointment of this combination, my mother's condition has become worse - depression, drowsiness, cough. Takes this combination for about one and a half months.

Now it's not so hot and dehydration does not threaten my mother, I would like to return my mother to indapamide. Which combination is better for the transition period: indapamide + losartan or indapamide + physiotensis? (I AM - the doctor of the emergency department, with the appointment of cardiac drugs I rarely encounter).
Administrators
admin
AlexandraAnd how could I help Indapamide, a monotherapy that your mom took, if she had a stroke? How can I cancel the prescribed treatment only on the grounds that it was better before, and then there was a stroke? Where are the guarantees that the present condition (depression, drowsiness) is not caused by the consequences of a cerebral infarction? Is there a regular monitoring of blood pressure figures?

With a cough that often causes drugs to lower blood pressure, you need to work and try changing the combination of drugs. For example, remove Physiotens from the therapy scheme by adequately increasing the dosage of Losartan or using a combination of Losartan with diuretics (you can use Lozap Plus, Wals H and other combinatorial drugs). If it does not help, change the scheme to the other side by excluding Lozartan and compensating this cancellation by suitable medications for the patient.
Guests
Lyudmila
Indapamide which is more effective - Russian production or imported?
Administrators
admin
LyudmilaIn principle, the same.If you are driven by prejudices and have enough money, take the import.
Visitors
Oksana13
Hello! The therapist appointed Indapamide (in the morning) and Lorist (evening). What drug can cause a cough (especially at night). Should I replace or cancel? Thank you!
Administrators
admin
Oksana13, Usually such manifestations are characteristic of Lorista more than for Indapamide. The question of cancellation or replacement of a specific drug is decided by the attending physician in accordance with your feelings, because the pill should be taken from the pressure for a long time, often for life and with a cough, of course, it will be problematic to feel good.
Visitors
MAKSHAPPY
Good afternoon. Tell me, can I take Indapamide with medications such as Nebilet, Cardiomagnol, Atenolol in one day?
Good afternoon. Tell me what to do. The doctor appointed Noliprel (2.5 mg + 0.625 indapamide) plus left me Egilok (I took it for the past 2 years, it was good, then a crisis,Initially, I was prescribed indapamide 2.5 mg, but he did not restrain the pressure plus there was shortness of breath, weakness, dizziness). Began to drink noliprel, thought there indapamide small absolutely a dosage, but the tachycardia did not stop, pressure 90/60, pulse 80-110, while ehilok the pulse 76-86 has strongly decreased. Now, closer to the evening, I need to take epiglottis, but I'm afraid of such pressure, but not to take a strong tachycardia. What to do, drink the Egilok? Today I can not get to a doctor - a day off.
Administrators
admin
MAKSHAPPY, Can. According to the instructions and experience negative consequences of such a joint reception should not be, besides these drugs potentiate (increase) the mutual positive effect when used together. Only it is necessary to divide reception of the given medicines on time (morning-evening). Plus, if you need to take two or more drugs at the same time, it is recommended to observe the interval between taking the tablets 15-30 minutes.
Administrators
admin
Klyshnikova Galina Dmitrievna, Egilok in any case must be left and taken in the morning. This drug regulates the heart rate or heart rate more and reduces the blood pressure to a lesser degree.

From the pressure, it seems that Noliprel is too strong, perhaps it's worth starting with a simple one - Enalapril, Lizinopril, to see how the body reacts. And why Indapamide is necessary, is there edema? From the question of this moment I do not see. If not, then perhaps you can do without a diuretic.
Visitors
valeraqazxsw
I drink indapamide 2.5 and amlodipine 5. The pressure drops, but the pulse rises. I add bisoprolol 5, everything falls and pulse, and pressure, but the pulse drops very low. What to do, how to reduce pressure, so as not to knock down the pulse? Prior to this, I drank concor 10-5 am with indapamide, but the problem with the pulse dropped to 40. Question to the doctor.
Administrators
admin
valeraqazxsw, Address to the internal doctor, because preparations for decrease in the raised arterial pressure it is a lot of and to appoint them it is necessary depending on a condition of your health and the previous treatment.Depending on the indications and contraindications for a particular patient is preferable to reduce the pressure to assign ACE inhibitors (enalapril, lisinopril, and many other products), calcium channel blockers (nifedipine, amlodipine), angiotensin 2 (losartan, telmisartan and other) receptors. But Bisoprolol or Concor is a medication to regulate and reduce heart rate and heart rate, and to a lesser extent to reduce elevated blood pressure.
Guests
armine
The doctor neurologist has appointed or nominated to drink constantly indapamid 2,5 ml, bisoprolol 1/2 mg in the morning and in the evening 5 mg enalapril. I had a lot of dizziness and pressure of 170/100. I've been drinking for two months. First pressure dropped to 110/70 HR 56, and then again in the morning was the heart rate to rise to 140/80 60. And somehow hurts constantly head and neck.
Visitors
Anna45
Question: I am 45 years old, taking the drug Indapamide 1.5 mg somewhere 1.5 years with interruptions. In the last month took both him and Grandaxinum aktoveginom (neurologist prescribed) because the normal pressure was 115/80, I stopped taking indapamide in the last week.There was swelling, especially the legs, sharply increased in weight, the pressure was normal, my heart began to beat violently. Explain, please, what to do, whether there is a link with medicines, can take what else?
Administrators
admin
Anna45, It is good to establish what is associated with puffiness (heart disease, kidney disease) and only then be treated. While it is possible to continue to take Indapamide and be examined in parallel to determine the causes of puffiness and poor health. Address to the doctor for internal consultation.
Guests
Галина 52 years old
Year I drink indapamide and lisinopril. I feel fine, but for 2 weeks my leg joints began to hurt. Can it be because of indapamide?
Administrators
admin
Галина 52 years old, You take medicine for a year, and 2 weeks started to get sick? Look for the cause in the joints, most likely the cause of arthrosis and is determined by the pictures of the joints.
Guests
olga
I had a pressure of 170/80. Has started to drink indapamid, pressure became stably low 100 \ 60.
Guests
Алексей 54 years old
There were problems with the pressure (periodically increased to 150-165 / 90). The doctor prescribed Indapamide (1.5 mg) with Concor (2.5 mg). I have been taking 1.5 months. The pressure is stable (on average 115/70), heart rate is 60-65.
Hello. For a long time I take coronale 5 ml in the morning and a cardiomon in the evening, the pressure is usually 120-140 / 80-100. Yesterday at the doctor in the evening the pressure was 160/101, she recommended indapamid retard 1.5 mg to the already taken drugs. Is it worth to reduce the dosage? Thank you.
Administrators
admin
Svetlana of Kiev, I do not prescribe any drugs after a single jump in pressure, the more you do not have a big jump, it can be a reaction to a dressing gown or stress. But patients do not leave me that easily, but they get an order of two weeks daily, in the morning and in the evening, to record the measured values ​​of pressure and pulse in order to see what kind of jump it was - one-time or permanent.If against the background of the therapy, the pressure still goes beyond the norms - then we add-change the existing therapy scheme. To Coronale add Indapamid retard possible, the rest is decided by the attending physician of the patient.
Guests
galena
People be careful with indapamide very increases uric acid in the blood and from this aching joints hand in the analysis. I drank it for three years and did not walk with my feet. Now I drink allopurinol has driven uric acid to 400 was 540 and legs easier.
Hello! For a year I have been taking indapamide (2.5 mg) + vamloset (5 mg + 160 mg) every morning. The pressure stabilized, the puffiness on legs or foots, has grown thin has grown thin for 20 kg. Everything was wonderful. I feel fine. But lately there have appeared rez by the type of cystitis. Can this be a reaction to indapamide? I really would not want to stop taking the drug.
Administrators
admin
Svetlana Makarova, Try to pass the general analysis of urine for the beginning and to make US of kidneys. Maybe the sand comes out, or an infection, or something else appeared during this time. It does not seem to be the result of taking Indapamide.
Guests
Lyudmila
Hello! For 50 years, literally today, it took the first time Enalapril Hexa and Indapamid Teva. There is no swelling and was not. I have a question, can I drink a lot of water?
Administrators
admin
LyudmilaIf the body requires a lot of water, but there are no problems with the kidneys and edema - drink.
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soyka5959
57 years old. Hypertension more than 10 years. I sat down on a low-fat diet. Restricted sweet. Two years the pressure was less than 120 at 75. I did not take any pills. Very rarely, when the pressure rises to 125. Relaxed, several times ate strong-salted food, the pressure for 2 weeks rose to 135, and when it rose above 140 was frightened, took the lorist 25, after some time, a diuretic furosemide. Then again to the lorist, the pressure rose slowly but surely. I drank captopril 25 mg under the tongue, and when I reached 182 at 95 I called an ambulance. Intramuscularly, magnesia relieved pressure. At the weekend, the ambulance recommended indapamide and enalapril 5 mg. After a day, the pressure is not strong, but rose to 150, now it's normal. 5 days later.I again use a low-salt diet. Can I still combine with indapamide? In the annotation to the drug it is indicated that enalapril and indapamide are cautious when salt is restricted? And another question, I provoked a rise in pressure by the introduction of salt into the body? A further uplift of anxiety, fright, or is it a regularity in hypertensive patients? But in fact I dieted for 2 years a fine pressure, measured 2 times a day?
Visitors
valinica
Read all the letters-questions and answers to them. I did not find the answer to my question: can I simultaneously take indapamide and magnesium B6? And whether it is necessary? Indapamidum I accept already within 14 months. It helps with both pressure and swelling. I am 68 years old. She began to sleep badly, they say magnesium B6 well calms the nerves. I live in the village, the doctor is the only one for all diseases. He advises poprinimat, but somehow uncertain. Thanks in advance for the answer.
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admin
soyka5959, I see more psychological problems in you, not organic ones. I would abolish indapamide altogether and do not worry about anything else, you do not have problems with organic hypertension.Better not read further, I will describe your problem for other people, or your consciousness can draw different pictures.

What we have is a patient who considers himself to be a hypertensive patient. He reads in the popular science literature absolutely correct postulate that a salt-free diet reduces the risk of increasing pressure and begins to follow a diet. All going well, the pressure is normal, but here comes the breakdown of food and the brain spins the story of the rise in pressure, so it creeps up every hour, there is anxiety, hysteria, bang comes a hypertensive crisis. First suppresses attack of magnesium, although it is also good to help, and a shot of sedative, if they knew the whole story and would like to figure it out.

This story I want to once again show that the man is a multi-faceted, in addition to authorities an important impact on his health has a mental attitude, the same psychosomatic medicine, which sometimes produces such trick, and we doctors try to treat these problems tablets, although in such cases better help the therapist.

P.S. Such a remarkable post about psychosomatics wrote until I saw in the recall of the visitor soyka5959 to another drug that it turns out to be accepting (or taking Tenoric).This is to the question that always indicate all the drugs taken at the moment. This district doctor can not say this, he already sees it in the map, but I do not.

valinicaWhen taking indapamide, magnesium can be increased from the body, which can provoke hypomagnesemia (magnesium deficiency in the body). So with long-term diuretic intake, Magnesium B6 does not hurt, and even vice versa.

As for the regulation of sleep in this way, there are doubts, because in this way you can assign any remedy for your sleep problems and not the fact that it will help. The causes of insomnia are many - from stresses, to side effects from medications taken. Circle of popular causes must be disassembled, examined, it is possible to prescribe tests. The magnesium deficiency can be determined by the banal blood biochemistry.
Guests
yuke
After 10 days, there is no improvement.
At discharge from the hospital, the doctor prescribed to me in the morning Noliprel Fort + Egilok 5 mg., At the Lunch Physiotense 0.4, in the evening Enalapril 20 mg. A month later he ordered to see a local doctor, who in turn appointed Lorist 100 mg in the morning. + Egilok 50 mg, lunch - Physiotense 0.4, evening - Amlodipine 10 mg.I drink already 10 months, pressure not below 150-160 / 100, sometimes I notice an edema of legs or foots. Advise a medicine more effectively.
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admin
Leonardo Lopez, It will be difficult to consult, because your treatment regimen passes the maximum dosages of drugs, and the effect, as I understood from the question, is insufficient. You can add a diuretic to your scheme, for example, Indapamide, Indap. It is permissible to introduce a combined preparation into the therapy scheme, for example, instead of pure Lorista, to give Loristu H or ND is a drug with a diuretic hydrochlorothiazide. You can also try to cancel the evening Amlodipine, because the drugs in this group can give a puffiness. But without a cardiologist, I would not remotely advise you to change it yourself or to change it yourself, to avoid crisis and recurrence, because the case is heavy, if by such dosages you can not reach enough blood pressure figures and its level still remains elevated.
Guests
Nina Stepanovna 64 years old
I'm sick with hypertension. The therapist appointed me in the morning indapamid and egilok, and in the evening lopaz and egilok. The pressure returned to normal.
Visitors
Anna C
Good afternoon! Always considered herself a hypotonic, pressure 100/60. On reception at the doctor pressure 140/90 (some times in a row). Cholesterol increased 6.9-7.3. Statins are prescribed, as well as indapamide 1.5 mg. I'm afraid that with the use of indapamide, the pressure will be low. Should I take it all the time? Thank you.
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admin
Anna CI think it's worth starting, but it will be seen. Moreover, the dosage of the drug is minimal. With the parameters of your blood pressure and cholesterol, it's good to tell your age if it's beyond the 40 chance that the pressure will return to normal and drugs to reduce blood pressure (in your case it's Indapamide) can be undone.
Visitors
nt.kstv
Hello. I have hypertension 2 tbsp. To me the doctor has appointed or nominated Valz 160 + 12, bisoprolol 5, but the pressure all the same keeps 150 on 89. To me have advised still to accept indapamid. Can I take drugs in such a combination? Before that, I still took amlodipine in this combination, but recently there has been a buzzing in my ears. But the pressure declined and stayed throughout the day. Thank you.
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Zinaida
Hello. Is it possible to take Indapamide together with Enalapril?
Administrators
admin
nt.kstv, I would then try a special form of Wals H with a diuretic hydrochlorothiazide. And take fewer tablets, and special multicomponent drugs were initially balanced by the manufacturer. And there is no other way, you need to select your combination of antihypertensive drugs, adjust the dosage and range of medications you take until you reach stable blood pressure within the age limit.
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admin
Zinaida, Can. According to the instructions and experience negative side effects with such a joint use should not be. The combination is recommended, the drugs potentiate the mutual positive effect.
Visitors
masha-1956
Age 60 years. Can I take diroton, indapamide and oxybradum simultaneously?
Administrators
admin
masha-1956, Can. All these drugs mutually reinforce the antihypertensive effect, so when prescribing dosages, you need to be careful not to cause a strong drop in blood pressure. Otherwise, there should not be any negative side effects when used together.
Visitors
mmmcom
Hello. To me of 48 years, a hypertension 2st. I take ramipril 10 mg, but the pressure is 150/90 and 160/90. Today was at the doctor to me have appointed or nominated still amlodipin 5 mg for the night. Is this possible? I thought that I would be added indapamide.
Administrators
admin
mmmcom, Such a combination is possible. You take Ramipril in the morning, and Amlodipine in the evening. For possible combinations with a diuretic, it is better to use ready-made combinations of ramipril with hydrochlorothiazide, rather than indapamide (these are commercial brands Amprilan NL and ND, Vazolong N, Hartil D and others). Here the decision in the matter of the appointment is with your doctor.
Visitors
Lika88
Good afternoon, I have a question for the doctor! Mom is 68 years old. Because of pressure spikes, Enalapril (5 or 10) has been taking for several years, depending on the pressure spikes. In the autumn the doctor has appointed or nominated additionally reception Indapamida. Mum accepts so medicines: at 18:00 Indapamide 1,5 tab in half, is closer to a dream Enalapril 5 or 10. In the afternoon at it or her weakness weak and pressure low 100 top (at working 125/90). By 23:00 the pressure begins to rise to 160. And weakness by the evening passes. Yesterday and today I decided to transfer the time of taking Indapamide to 14:00 (from 18:00). Pressure in the afternoon in the norm is now 126 upper, but very strong weakness and "fuzziness" in the head and dizziness remained. Is it possible with the reception of Indapamide such pressure jumps, dizziness and weakness? Can change the drugs? Only recently have pierced a course Cavintonum and other preparations for vessels, but a giddiness and an ambiguity in a head does not come. Thanks in advance!
Guests
Olga
I have a working pressure of 90/60. Age 50. Pressure jumps, headache, weakness started. I took indapamide within a month. I felt well, no problems.
Administrators
admin
Lika88It is better to take medicines from pressure correctly. I would change the schedule for the morning reception of Indapamide and / or Enalapril in dosages that maintain the normal pressure level and do not cause the negative effects described in the question, and in the evening gave Amlodipine or its commercial counterparts, you can try Moxonidine, Physiotens. So it will be more correct taking into account the physiology of man and the purpose of medicines. If you change your mother's drugs for others, you should consult your doctor so that their use is not contra-indicated, taking into account the concomitant diseases and the previous experience of taking.

Dizziness and weakness can also be caused by circulatory insufficiency and are not associated with medications, this option can not be ruled out. This condition is treated with drugs that enhance blood circulation (Fezam, Nicergolin and others).
Visitors
Ivan_360
Hello. Tell me, please, the doctor appointed Indapamid 1.5 in the evening and Giposart 8 mg. in the morning.Whether prompt correctly the doctor has appointed or nominated indapamid in the evening, because in the instruction it is written to accept in the morning?
Administrators
admin
Ivan_360, No one prescribes diuretics at night to run less in the toilet at night, this is anti-physiological, only if another diuretic is taken in the morning or a large dosage is required for serious edema. Judging by the description of the problem, you do not need such a need. I would apply both drugs in the morning or even take a combinatorial medicine that would include an antihypertensive component and a diuretic in one tablet.
Guests
Lana-53
53 years old, had a hypertensive crisis 4 years ago, hypertension of the 2nd degree, the doctor prescribed indapamide 2.5 mg, enalapril 5 mg, and bisoprolol, since. tachycardia often, I drink these tablets constantly in the morning. Bisoprolol at first drank, and then began to feel a pressing pain in the heart after its administration, now only indapamide and enalapril. The pressure from the morning of 130 to 95, by the evening decreases, thanks to the pill becomes 105 to 90, and when 110 to 85, but some kind of fatigue and weakness is felt. Last time pain in the heart is constantly.
Visitors
ChadovaNS
ChadovaNS, Moved your question to the drug Indap, which was mentioned in the question.
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Guests
kosmos
Long took indapamide 1.5 mg and monopril, the pressure was normal. Has stopped reception indapamida after an attack of a gout. The pressure rose sharply. Replaced indapamide with amlodipine - edemas appeared.
Guests
Galya is 62 years old.
I had high blood pressure. I even drank Cloophelin, but he helped for a short time. The doctor changed the pills and administered Indapamide and Bisoprolol. There were severe edema on the legs. A miracle happened! Edema passed and pressure 110 to 70. But I still drink Panangin, so the doctor ordered.
Visitors
marina200562
Tell me, please, with indapamide should you drink asparkam? At me on a background of reception indapamida there was a palpitation in the mornings about 100 blows. I read that asparks (or panangin) helps in disturbing the rhythm.
Administrators
admin
marina200562When taking indapamide, hypokalemia may develop and then potassium preparations like Asparkam or Panangin are indicated. You can try to add these drugs to the treatment regimen.Also, maybe the cause of your tachycardia is in another, for example, in a previously undiagnosed disease. I advise you to see a doctor for a full-time consultation, preferably if it's a cardiologist.
Guests
marietta
I have a question. I have been drinking Concord 125/85 for 3 years already. But I'm constantly swelling left leg for 25 years only in the summer. Sometimes in winter, but rarely. The doctor appointed Indapamide. Can you drink together Concor and Indapamide? In fact them it is necessary to drink on an empty stomach or as?
Administrators
admin
mariettaThe drugs mentioned in the question can be taken together. Take them better in the morning, on an empty stomach. Additional side effects when using Indapamide and Concor should not be, plus these drugs enhance the antihypertensive effect of each other when used together.
Visitors
nadya02-09
I was discharged from Arifon, which included Indapamide. Is it possible to use not Arifon, but Indapamide, since Arifon costs 380 rubles, and Indapamide 21 rubles?
Administrators
admin
nadya02-09If there is no possibility to spend on an expensive and branded medicine, you can replace it with a cheaper analogue. In your case, the replacement will be justified, if earlier you Indapamide in a simple (rather than a retarded form, as in Arifone) did not accept.
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Alexander the Transfiguration
About a year ago there was an ischemic stroke at 56 years old. I now take indapamide 2.5, amlodipine 10 - in the morning. In the evening: atorvastatin 20, amlodipine 10, cardiomagnetic 25. Pressure within 130/80, edema on my legs now, I can not walk the stairs between floors, the joints (like wadded, friable), cough are very painful. At night, go to the toilet every 2 hours. Muscular spasms of the legs. Whether advise it is not necessary to change a dosage and the scheme or plan of reception of medicines because there is an accrual of by-effects and I accept them about one year?
Administrators
admin
Alexander the Transfiguration, Amlodipine morning would be replaced with another antihypertensive drug, and if the swelling continues to increase, then the evening reception of this medicine should be canceled and replaced with another drug.Since each of them has its own set of contraindications and side effects, it is necessary to know the concomitant diseases and previous treatment performed, contact this question with the treating doctor who is observed in the internal order, it is better if it is a cardiologist.
Visitors
anna.mart2011
Good afternoon. I the hypertensive patient with the big experience. In 2014. the doctor has appointed or nominated to me Valz 40, betalok 50 and indapamid (before accepted enalapril 10 and egilok 25). Like everything was not bad (the pressure was up to 150, sometimes it dropped to 100). But in August 2017g. to me have raised or increased Vals up to 80 with a diuretic morning and Valz 80 without a diuretic evening, betalkov 50, betaserk. And indapamide was canceled. The pressure is now 170 to 190. A week ago they added veroshpiron 25 for lunch - the pressure does not fall. It seems to me that with indapamide I felt better. But the doctor stubbornly does not want to appoint me indapamide. What is your point of view?
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admin
anna.mart2011, It is necessary to ask your doctor why he does not want to assign you Indapamide. Perhaps he saw in your analyzes that potassium or magnesium is being washed away (although this diuretic not so strongly removes these elements,but the subsequent appointment of potassium-sparing diuretic Veroshpirona leads to similar thoughts) and this was the reason for the cancellation. And if it's just a medicine that your doctor does not like to appoint, then there's no point in canceling it. It may be worthwhile to contact another specialist for treatment correction, the more negative the values ​​of blood pressure after the abolition of Indapamide you notice and if there are no other reasons, then it is necessary to return the medication.
Visitors
Elena_bendz
My mother is 87 years old. In 2010, her right kidney was removed from oncology, and left cysts. Is it possible to use indapamide 1.5?
Administrators
admin
Elena_bendzIt is necessary to look at the function of the kidney and only then decide on the use of diuretics. Remotely such a question can not be solved, contact the nephrologist in person.
Guests
Lyudmila
When buying indapamide, the pharmacy was told that it was ineffective. A medicine can not cost 10 rubles., Advised the indap. If so, why is it produced?
Administrators
admin
LyudmilaIn Indap contains the same active substance as in Indapamide. The question is rather to the producers, rather than to the medicines. Pharmacists are not doctors and they can not advise medicines because of their education.
Is it possible to combine the intake of the coronal and indapamide?
Guests
Tamara 60 years old
Against the background of stress there was a steady increase in pressure. Below 140-150-90 did not fall, sometimes it was higher. Enalapril did not help (drank daily 10 mg in the morning and 5 mg at night). Assigned enalapril hexal 10 mg and indapamide 1.5 in the morning and afobazol 1 t.3 times. Against the background of taking indapamide, heart rate 110, weakness, sweat hail, back pain, dizziness. Indapamide is a very dangerous drug. Take it very carefully, even in the smallest doses. I do not advise anyone. I used to try amlodipine - my legs are very swollen. Take medication very carefully, even according to the doctor's prescription. Sometimes it seems that doctors do not read the instructions and the more so the interaction of medicines.
Administrators
admin
Lyubov Konovalova, Can. With the combined use of Coronale and Indapamide, the antihypertensive effect is potentiated, which may require correction of the doses of these drugs in the direction of their decrease.
Guests
Gregory
Good evening. The cardiologist prescribed indapamide and niperten, but the pressure still rises to 150/100. The therapist has registered to add ko-pianevu. Are these drugs compatible? It's embarrassing that I already drink indapamide, the co-perineva also includes indapamide. Is not there a lot of diuretic? Help, please, advice.
Administrators
admin
GregoryWith Ko-Perineva, your therapist got excited. Or it is necessary to cancel Indapamide and add Ko-Perineva or add Perineva's drug, which is without a diuretic, to the treatment plan with Indapamide and Niperten.
Visitors
Sofia
Good afternoon. My diagnosis is catarrhal reflux-esophagitis. Focal antral gastritis. I accept Нофлюкс, мотилиум and гевискон 2 weeks.
Can I take indapamide retard with these drugs? I used to be discharged at elevated blood pressure. And now I have a strong swelling of the face and throat. In the morning I can not open my eyes and my throat swells so much that it's difficult to swallow.
Administrators
admin
Sofia, Indapamide can be used in conjunction with the drugs indicated in the question. Additional side effects should not be. I want to draw your attention to the fact that the side effects of Motilium are delayed by urine, so potentially I would consider the possibility of edema due to the use of this medication, although it is not clearly indicated in the side effects.
Guests
Raisa 53goda
Hello. I want to say that indapamide is a very dangerous drug. I drank just one tablet, after 5 minutes my lips turned blue, my whole body flushed, big blisters appeared, my face was numb, it was hard for me to breathe, to move. It's good that I had suprastin in my home at the injection.
Guests
Larisa Sadiq
I drink indapamid 1.5 mg the second day, there was a nausea and pains in the right hypochondrium. The pressure returned to normal.
Guests
Lyudmila
I am 65 years old. Previously, I took indapamide 2.5 mg alone, Lorist 25 mg, once a day in the morning. There was a problem with the heart, I do not associate with taking medications. After a visit to the cardiologist, I take Lorid, 25 mg, amlodipine 10 mg, veroshpiron 25 mg, atcemcarol, once a day in the morning, and atorvastatin 20 mg in the evening for 1.5 months. There were edemas on the legs, pains in the knee joints.
Visitors
Olena
Good afternoon. 58 years. Hypertension, high cholesterol. The cardiologist has appointed in the morning indapamide, in the evening atorvastatin-teva 0.1 and cardiomagnet. I feel fine, cholesterol for half a year is almost normal. But at me 1 stage of an arthrosis, the knee hurts, and me confuses, that indapamid raises uric acid. Advise, on what preparation it can be replaced, not too expensive? Unfortunately, constantly monitoring the potassium on the analysis of blood there is no possibility, the doctor is so loaded that at the reception of the tests and does not look.The pharmacist is advised to take Pananginum, and again to monitor the blood. So we read everything on the Internet.
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admin
The visitor question of the Directory PAN. moved to the required section:
To me 65. I accept indapamide, pressure was stabilized, but from reception indapamida began to recover. The time of taking September-March per month was 2 kg (my height was 173), 82-84 was 90 kg. What should I do?
PAN.If there is an understanding that the gain in weight is caused by taking Amlodipine, and not by other factors (nutrition, swelling, etc.), then the replacement of the drug for another is shown. To do this, consult your doctor, if it is a cardiologist. If the testimony is impossible to replace (this is extremely rare, if the patient is only suitable for a particular drug, and all others are allergic or other adverse reactions), then you have to put up with excess weight, there are already choosing less than two evils.
Administrators
admin
OlenaIf there is no excess of uric acid in the assays, then you can calm down and continue taking Indapamide. The indication in the instructions for changing the indices in the blood of patients taking this diuretic,for real problematic cases, which are rare. From the fact that you cancel it, the progression of arthrosis will not stop. It is necessary to protect your joints and undergo periodic courses of chondroprotectors with symptomatic therapy of pain and inflammation if necessary. Analogue Indapamide cheaper you will not find.

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