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Cefotaxime - instructions for use, analogs, reviews and release forms (injections in ampoules for injection 500 mg and 1 g) drugs to treat infections in adults, children and in pregnancy. Breeding (on water or novocaine) and the action of an antibiotic

Cefotaxime - instructions for use, analogs, reviews and release forms (injections in ampoules for injection 500 mg and 1 g) drugs to treat infections in adults, children and in pregnancy. Breeding (on water or novocaine) and the action of an antibiotic

In this article, you can read the instructions for using the drug Cefotaxime. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Cefotaxime in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Cefotaxime in the presence of existing structural analogues.Use to treat infectious and inflammatory diseases in adults, children, as well as during pregnancy and lactation. Breeding (on water or novocaine) and the action of an antibiotic.

 

Cefotaxime - 3-generation cephalosporin antibiotic of a broad spectrum of action. Has a bactericidal effect by inhibiting the synthesis of the bacterial cell wall. The mechanism of action is due to the acetylation of membrane-bound transpeptidases and the cross-linking of peptidoglycans, which is necessary to ensure the strength and rigidity of the cell wall.

 

Highly active against Gram-negative bacteria (resistant to other antibiotics): Escherichia coli (E. coli), Citrobacter spp., Proteus mirabilis (Proteus), Providencia spp., Klebsiella spp. (Klebsiella), Serratia spp., Certain strains of Pseudomonas spp., Haemophilus influenzae.

 

Less active against Streptococcus spp. (including Streptococcus pneumoniae) (streptococcus), Staphylococcus spp. (Staphylococcus aureus), Neisseria meningitidis, Neisseria gonorrhoeae, Bacteroides spp.

 

Resistant to the action of most beta-lactamases.

 

Pharmacokinetics

 

Quickly absorbed from the injection site. The binding with plasma proteins is 40%. Widely distributed in tissues and body fluids. Achieves therapeutic concentrations in the cerebrospinal fluid, especially with meningitis.Penetrates through the placental barrier, excreted in breast milk in low concentrations. 40-60% of the dose is excreted unchanged in 24 hours, 20% in the form of metabolites.

 

Indications

 

Infectious-inflammatory diseases caused by sensitive microorganisms, including:

  • CNS infections (meningitis);
  • respiratory tract infection and ENT organs;
  • urinary tract infections;
  • infection of bones and joints;
  • infections of the skin and soft tissues;
  • infections of the pelvic organs;
  • abdominal infections;
  • peritonitis;
  • sepsis;
  • endocarditis;
  • gonorrhea;
  • infected wounds and burns;
  • salmonellosis;
  • Lyme disease;
  • infection against the background of immunodeficiency;
  • prevention of infections after surgical operations (including urological, obstetric-gynecological, on the organs of the digestive tract).

 

Forms of release

 

Powder for the preparation of solution for intravenous and intramuscular injection (injections in ampoules for injection) 250 mg, 500 mg and 1 gram of powder for reconstitution in water for injection or novocaine.

 

Instructions for use and dosage

 

The drug is administered intravenously (either jet or drip (in a dropper) and intramuscularly.

 

With uncomplicated infections, as well as with infections of the urinary tract - in / m or / in 1 g every 8-12 hours.

 

In uncomplicated acute gonorrhea - in / m in a dose of 1 g once.

 

For infections of moderate severity - in / m or / in 1-2 g every 12 h.

 

In severe infections, for example, with meningitis - iv every 2 to 8 hours, the maximum daily dose is 12 g. The duration of treatment is set individually.

 

In order to prevent the development of infections before the surgical operation is introduced during the initial anesthesia once in a dose of 1 g. If necessary, the administration is repeated after 6-12 hours.

 

At caesarean section - at the time of application of the clamps to the umbilical vein - iv in a dose of 1 g, then 6 and 12 hours after the first dose - in addition to 1 g.

 

Premature and newborns under the age of 1 week-in / in a dose of 50 mg / kg every 12 hours; at the age of 1-4 weeks - in / in the dose of 50 mg / kg every 8 hours. Children with body weight ≤50 kg - in / in or / m (children over the age of 2.5 years) 50-180 mg / kg in 4-6 introductions.

 

In severe infections (including meningitis), the daily dose for prescribing to children is increased to 100-200 mg / kg, IM or IV for 4-6 injections, the maximum daily dose is 12 g.

 

Rules for the preparation of injection solutions

 

For intravenous injection: 1 g of the drug is diluted in 4 ml of sterile water for injection; the drug is injected slowly for 3-5 minutes.

 

For intravenous infusion: 1-2 g of the drug is diluted in 50-100 ml of the solvent. As a solvent, use 0.9% solution of sodium chloride or 5% solution of Dextrose (glucose). The duration of the infusion is 50-60 min.

 

For the / m introduction: 1 g is dissolved in 4 ml of the solvent. As a solvent, water for injection or 1% solution of Lidocaine (novocain) is used.

 

Side effect

  • headache;
  • dizziness;
  • impaired renal function;
  • oliguria;
  • nausea, vomiting;
  • diarrhea or constipation;
  • flatulence;
  • abdominal pain;
  • dysbiosis;
  • stomatitis;
  • glossitis;
  • pseudomembranous enterocolitis;
  • hemolytic anemia, leukopenia, neutropenia, granulocytopenia, thrombocytopenia, agranulocytosis;
  • potentially life-threatening arrhythmias after a rapid bolus injection into the central vein;
  • increased urea concentration in the blood;
  • a positive Coombs reaction;
  • phlebitis;
  • soreness along the veins;
  • morbidity and infiltration at the site of intramuscular injection;
  • hives;
  • chills or fever;
  • rash;
  • itching;
  • bronchospasm;
  • eosinophilia;
  • anaphylactic shock;
  • Superinfection (vaginal and oral candidiasis).

 

Contraindications

  • pregnancy;
  • children's age to 2.5 years (for intramuscular injection), with caution in newborns;
  • increased sensitivity (including penicillins, other cephalosporins, carbapenems).

 

Application in pregnancy and lactation

 

The use of cefotaxime in the first trimester of pregnancy is not recommended.

 

Application in the 2nd and 3rd trimester of pregnancy and lactation is possible only in cases where the intended benefit to the mother exceeds the potential risk to the fetus or infant.

 

It should be borne in mind that after intravenous administration of cefotaxime at a dose of 1 g in 2-3 hours the maximum concentration of the active substance in breast milk averages 0.32 μg / ml. With such concentration, a negative effect on the oropharyngeal flora of the child is possible.

 

In experimental animal studies, teratogenic and embryotoxic effects of cefotaxime were not detected.

 

Use in children

 

With caution apply cefotaxime in newborns.

 

special instructions

 

In the first weeks of treatment, pseudomembranous colitis can occur, which is manifested by severe prolonged diarrhea. At the same time, stop taking the drug and prescribe adequate therapy, including Vancomycin or metronidazole.

 

Patients who had a history of allergic reactions to penicillins, may have increased sensitivity to cephalosporin antibiotics.

 

When treating the drug for more than 10 days, monitoring of the peripheral blood pattern is necessary.

 

During treatment with cefotaxime, it is possible to obtain a false positive sample of Coombs and a false positive urine reaction to glucose.

 

During treatment, alcohol can not be consumed, since effects similar to that of Disulfiram (facial hyperemia, stomach and stomach spasms, nausea, vomiting, headache, decreased blood pressure, tachycardia, dyspnea) are possible.

 

Drug Interactions

 

Cefotaxime increases the risk of bleeding when combined with antiaggregants, non-steroidal anti-inflammatory drugs.

 

The risk of kidney damage increases with the simultaneous administration of aminoglycosides, polymyxin B and "loop" diuretics.

 

Drugs that block tubular secretion, increase plasma concentrations of cefotaxime and slow its elimination.

 

Pharmaceutical interaction

 

Pharmaceutically incompatible with solutions of other antibiotics in one syringe or dropper.

 

Analogues of the drug Cefotaxime

 

Structural analogs for the active substance:

  • Intrataxime;
  • Kefotex;
  • Clafhorn;
  • Claforan;
  • Clafotaxime;
  • Liphoran;
  • Oritax;
  • Ortaxime;
  • Resibelact;
  • Spirozin;
  • Tax-o-bid;
  • Taltsef;
  • Tarcephoxime;
  • Tirotax;
  • Cetax;
  • Cefabol;
  • Cefanthral;
  • Cefosin;
  • Cefotaxime Lek;
  • Cefotaxime sodium;
  • Cefotaxime Sandoz;
  • Cefotaxime Vial;
  • Cefotaxime sodium salt.

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Reviews (123):
Guests
gurgen
A good antibiotic for the treatment of pneumonia, I was assigned to the hospital when I got there with an inflammation of Ceftriaxone, so it was a sickly infection and 5 days of painful injections did not bring me closer to recovery. And then the doctor privately advised me to buy Cefotaxime, with novocaine for breeding, so that it would not hurt so much. And on the third day of receiving this medication, I received an improvement in the x-ray of my lungs and recovery did not wait. As a result, he discharged in a week with a slight cough, which he cured in the polyclinic without antibiotics. So take Cefotaxime with pneumonia, but do not forget that it is poison with alcohol and it will be very bad, these are those who treats at home and loves to lay their collars, with this strictly.
Guests
Irina
Excellent antibiotic.
Guests
Kate
A good drug.At me to the son of 5 years have put a bronchopneumonia and have appointed or nominated this preparation. We bought - started to do, were treated at home and he helped us a lot.
Guests
Elena Mikhailovna
Tell me! To us today have put suspicion on a pneumonia. The girl is 10 years old. Have registered the same medicine. In the morning, the first injection was made - there was no temperature, and in the evening after the second injection she got up at 37.2. We are very worried. Today we did X-rays, but the results will be ready only on Tuesday ....
Administrators
admin
Elena MikhailovnaThe situation described by you is often encountered. The rise in temperature, after the start of treatment with antibiotics (in your case - Cefotaxime), is due to the death of a large number of bacteria and the entry of pyrogenic substances into the bloodstream of the patient (particles of dead bacteria and the products of their vital activity). All this provokes a rise in temperature. So if the diagnosis is confirmed - you can continue treatment with this antibiotic and fix the dynamics for 3-5 days after the start of treatment.
Guests
Elena Mikhailovna
Thank you very much for the answer. And then we have already begun to sound the alarm, because the cough is long, but at the same time the temperature never rose. Can we still consult? The drug was prescribed in a solution with water and ice capsules - 0.85 mg. The first day (today) was done by a nurse. You do not tell me how much in what proportions you need to mix our drug, ice cream and water for injections at a fixed dose of 0.85. If it's not difficult, just explain on the divisions of the syringe.
Administrators
admin
Elena Mikhailovna, With Cefotaxime I do not work densely, therefore I will not tell you the exact proportions of non-standard dosages for children. So it's better to ask the nurse who put your baby on the first injection. I somehow use Ceftriaxon, so I'll explain everything to him.
Guests
Tatyana
We have a long cough than just not treated does not pass. Today we went to the reception and asked for injections. Today was the first. We bred 2 mm of ice-breaker + 2 mm of water for an injection into 1 ampoule.
Guests
Marina
Mom was assigned "Tsefatoxim". Today I took the first injection in / in - 2d. Not much for the first time?
Administrators
admin
MarinaIf intravenously, and even 2 grams, then the problem must be really serious. And in fact, this dosage is quite acceptable, but you need good reasons - the severity of the process, a strong bacterial invasion, to prescribe the maximum dosages of Cefotaxime.
Guests
marina
Hello. I was prescribed a cefotaxime doctor, but I breast-feed the baby. What should I do in this situation?
Administrators
admin
marina, Stop breastfeeding while taking an antibiotic. Milk can be expressed and poured. There are no other options when taking cefotaxime.
Guests
Alla
Can an arrhythmia occur when taking cefotaxime?
Administrators
admin
Alla, In the instruction arrhythmias are noted at fast bolus introduction of a drug Cefotaxime intravenously.Although, if the excretory system works poorly or the recommended dose of the drug is exceeded, then I think this effect can occur even with intramuscular injection, but this is more of a special case of a side effect. The answer to your question is yes, it can.
Guests
galena
We take this drug for the second day the temperature is 37.3 then 38.2. Why is that?
Administrators
admin
galena, I told you why. Look closely at the reviews and comments on the drug before asking a question. During treatment with antibiotics (including Cefotaxime) there is a massive death of bacteria that cause the disease. As a result of this process in the blood there is a large number of corpses of bacteria and products of their vital activity, all these are strong pyrogenic substances that cause a rise in temperature. To reduce this effect, you need a lot of fluid (if there are no problems with the kidneys), to remove this debris from the body.
Guests
Nadia
Hello.My husband was pricked in the hospital with cefotaxine, please tell me through how many children can be planned?
Administrators
admin
Nadia, Children can be scheduled the day after the last injection, since the half-life of Cefotaxime is 0.8-1.4 hours.
Guests
Irina
Good afternoon. I am treated with cefotaxime from a genyantritis. But wrongly began to prick it, that is, 1g of cefotaxime + 2ml of water for injection + 2ml of lidocaine and injected intramuscularly at once, that is, the medicine was cloudy, as a result, a bruise and pain on the buttock. What other consequences can there be?
Administrators
admin
Irina, Usually such violations of the tri-preparation of the solution or its introduction lead to consequences in the area of ​​the injection (abscesses, suppuration, etc. side effects) that you received. Other changes should not be, but just in case, I recommend to monitor the temperature and general condition of patients with impaired technique of drug administration.
Guests
Tatyana
Have appointed or nominated at a cystitis, after 7 days a course of a flexidum. On the third day there was an itch. When to finish, if the clinical symptoms have disappeared? There is no information about the minimum rate anywhere.
Administrators
admin
Tatyana, In this section, consultations and reviews about the use of Cefotaxime. 7 days the standard time of antibiotic therapy in uncomplicated cases.
Guests
Lena
My daughter prescribed cefotaxin, and can I pierce some vitamins to raise my immunity?
Administrators
admin
LenaIn one syringe with antibiotic - it is impossible, and so it is possible. But not necessarily. And if you prescribe yourself vitamins, then take the best in tablets or capsules, if she is already an adult and can swallow the pill herself.
Guests
Yuliya.
Treated in hospital hr.ooophoritis. Cefotaxime 1.0 2 r / d was administered together with nystatin, metronidazole, diclofenac.
On the first day - a syndrome of an acute abdomen, the second - a tachycardia, the third - t 38 °. Then fell to 37.3. A runny nose started, a cough, and a sore throat.
The course is 7 days. Has left.One week the temperature is 37.3, the runny nose has passed, lymph nodes, kidneys, tachycardia have become inflamed. Analyzes at an extract all in norm or rate. Does not the given antibiotic or the reason in the other suit me?
Administrators
admin
Yuliya.Most likely, you have against a worsening of chronic disease there was a decrease in immunity and if the underlying disease in the hospital you stopped antibiotic, then with the accompanying cold you still have not coped. And with inflammation in the body can be a poor state of health and tachycardia. At the time of discharge, you had to pass tests, even if you had a chronic oophoritis completely, or you can still have all the symptoms and against the background of an untreated underlying disease. Do not do anything yourself, and do not get cured on the Internet - go to a gynecologist, maybe you need to be treated like a woman, or maybe just a cold, but you can not check it out remotely. The case is not trivial.
Guests
Marina A
A good drug. We put a lacunar sore throat. Have appointed or nominated on 2 mg two times a day for 7 days.On the third day, I did not observe any signs of illness, the temperature fell on the first day of taking the drug. No side was! The only negative is that he is wildly sick (even on Novocaine).
Guests
Diana
At 6.5 pregnancies, I was prescribed digitaloksim on novocaine, I have inflammation of the kidneys? How to proceed?
Guests
Elmira
Marin, try it with lidocaine (unless of course there are contraindications), sting it 7 days to 1g. I dilute with 4 ml. icekaina - excellent, if you can say so))) 1 time pricked with novocaine, a little pain did not collapse (((it hurts, but I do not feel anything ... The drug really helps, the doctor prescribed 7 days for 2 injections, pregnancy 37 weeks, the diagnosis of "E. coli."
Administrators
admin
Diana, Although with regard to the antibiotic Cefotaxim and there were changes in the part of taking during pregnancy and feeding, which I introduced into the Handbook, but for your case, namely during the first trimester of pregnancy, there is a ban on the use of an antibiotic. Although 6.5 may not be weeks, but months, then look in the instructions, there is a footnote that if you really need it, you can also be treated, under the supervision of a doctor.

Perhaps the clinical base of research on the effect on the body of a pregnant woman or fetus is not enough, and not harm, but we live in the present day, and not the future. I would advise you to go to a specialized therapist for pregnant women (there are women's consultations) or to a gynecologist who is watching you. But inflammation in the kidneys in any case have to be treated, even if it's another antibiotic, but it's necessary.
Guests
Dmitriy
Is it possible to dilute cefatoxin with sodium chloride for intramuscular injection?
Administrators
admin
DmitriyIt can be diluted with water for injections, but it will be more painful. Allergic people are only watered and bred, if the anesthetics have an allergy.
Guests
Marina
Creepy bronchitis, in the pharmacy advised to pierce cefotaxime, only made the first injection, diluted with lidocaine.
Guests
Tasia
Pneumonia. They pierced 7 days. Excellent result. Diluted 1% with lidocaine. Not at all sore.
Guests
Tatyana
My husband fell ill. Cough is severe. They injected cefotaxime twice a day for three days, diluted with water for injection and lidocaine. A tremendous result. Has recovered.
Guests
Dmitriy
The heat lasted a week. Have registered this medicine (be damned). Allergies to anything not. On day 2 of the injections, the whole face poured out. On the same day, when I injected cefotaxime, I had an anaphylactic shock!
Guests
Tatyana
The drug is good, but only a lot of toxins are given off by dying bacteria - the temperature is at night 38.7 3rd day. I'm afraid to sleep.
Visitors
igor 555
Hello, tell me, please, did the washing of the lacrimal canal in the hospital (the child is 6 months old). After the procedure we went home. By the evening there was swelling. In the morning, even more. We went to the hospital, they immediately put us and assigned to prick the antibiotic cefotaxime 2 times a day for 450 mg intramuscularly.One nurse diluted the antibiotic with novocaine, then another changed and said that with lidocaine it would be less painful. And the third said that children under the age of lidocaine can not. Tell me, please, whether it is possible at all to inject an antibiotic intramuscularly into a 6 month old baby. Is it not dangerous, then that we diluted the day with novocaine, the day - with lidocaine. And the course of treatment was 3 days.
Administrators
admin
igor 555, In hospitals, usually bred by what is available at the moment in stock, then under this business come up with all sorts of tales that this can not be, and with this you can. It's from our poverty.

There is no fundamental difference between Novocain or Lidocaine if the child does not have allergies to these components of the injection. I prefer Lidocaine, since there is a statistic that Novocaine gives more allergic reactions and reduces the activity of antibiotics. But I think that this change from one drug to another is not allowed at all, if it's a small child, then the nurses blundered. Than started, the better and to prove the full course of treatment. To children, Cefotaxim pricks are indicated, if there are grounds and they are recommended by a doctor.
Visitors
ekaterina
Hello! To me have registered a course of a cefotaxime (5 days in / m, 2 times a day). I breast-feed, while koljat - I express. After what time after the last injection, can I give the baby a breast?
Administrators
admin
ekaterina, The half-life of the drug Cefotaxime is about 1 hour. That is, by the evening of the same day, when you were given an injection of an antibiotic in the morning, you can continue breastfeeding or the next day if you pierce the course in the evening.
Guests
Olga
I blew my son from a protracted cough. I helped on the 8th ampoule!
Visitors
saliha
But look, then you said that in an hour it is excreted, so then you can then feed after the injection in two hours? Thanks for the answer.
Administrators
admin
saliha, Of course not. The elimination issue is raised only after the end of the course of treatment. If you are injected three times a day, then in the blood, and hence in milk, there is a constant concentration of antibiotic Cefotaxime and you can not breast-feed.

And for understanding, 1 hour is the half-life of the drug, when the concentration of the drug falls two times, then after another hour another half-elimination - a quarter of the drug in the blood from the initial, etc. As a result, 4 injections per day (a not three as prescribed, it's wrong) completely overlap the therapeutic spectrum of the drug and it is constantly present in the blood, which is necessary for recovery.
Guests
Galina Melnikova
The drug is excellent! I take with novocaine + Calcium 5 mg. Improvement is felt even with the first two injections. However, I am still in the stage of treatment. I hope that at this rate I will soon be well.
Visitors
sav
Have appointed a child cefotaxime with adenoiditis, pharyngitis and eustachyte. The temperature (and it was 39.7) quickly began to subside, but on the third day it rose again to 37.6. A severe diarrhea began, the child lies with a layer, the throat is still red, adenoiditis is there. How to help? Whether to cancel an antibiotic (the doctor said that a course of 7-10 days is required)?
Administrators
admin
sav, To take another two days, but if the diarrhea is strong, then you can go early and see a doctor who prescribes an antibiotic, maybe the drug did not fit, and maybe a viral infection, in which the antibiotic will help poorly. There may be several reasons, you can not understand it remotely, but you should not abolish Cefotaxime yourself, it's probably just that it works on your child, given the darkness of the diseases that suddenly arose.
Guests
Yuri
Is this drug prescribed for cystitis?
Administrators
admin
Yuri, Cystitis antibiotic Cefotaxime is indicated. Consult your doctor to determine the correct dosage.
Guests
nastia
I was given this antibiotic in the hospital. On a background of it or him there was a thrush and a strong itch of a vagina.
Guests
Alisa Ivanovna
A preterm 35-week-old child who received a cefotoxime 3 weeks after cesarean section (3,410 kg 51 cm) for a second course of antibiotic treatment, which is administered without lidocaine and intramuscularly from which the child is difficult to calm,long time screaming and wriggling with pain. Mom is not around. It seems to me that this is an extremely cruel method of drug administration. In the instruction for cefotaxime, children up to two and a half years are advised to administer it intravenously.
Guests
Alya
Good evening! With sinusitis, they prescribed cefotaxime for 2 injections a day for 5 days. Has made 8 of 10 injections. Does not stand up already pop. Can I stop at 8 if the doctor saw significant improvements on the second day of injections? In this case, every 3 days, the nose is washed with cefotaxime.
Administrators
admin
Alya, I think you can. But the attending physician decides, remotely advising this is difficult. With a genyantritis do not joke and if you do not cure the disease to the end, then you will treat a relapse and the priest thank you just will not say for a second course of stronger antibiotics.
Visitors
197860811
Good evening! The child in the nasopharynx found a Staphylococcus aureus 10 * 3. The pediatrician prescribed cefotaxime + nystatin ointment to mix 1 to 10 and smear the nose and yawn 2 r.v day.Question: Is it possible to store the mixture in the refrigerator for 10 days or to prepare a new one every time? And will this mixture help to overcome Staphylococcus aureus? Thank you.
Administrators
admin
197860811If Staphylococcus aureus is sensitive to Cefotaxime, then it is this antibiotic that will help sanitize the nasopharynx of the child. And it must be taken correctly (that is, in injectable form, intramuscularly, if the child's age permits). But what will give nystatin ointment with Cefotaxime, and even in such an original feed is unknown to me. Most likely, nothing will give, because the pathogen is inside, and does not sit on the mucous membrane of the nasopharynx. The child as I understand there is no fungal disease, and the likelihood of fungal complications when taking antibiotics is small and I do not prescribe anything to my patients, in 90% of cases everything ends without antifungal therapy.

Summarizing. Do sowing from the throat, nasopharynx, the ears of the baby with the definition of the sensitivity of the sown pathogen to antibiotics and let the doctor pick up the most effective antibiotic that is allowed to a toddler of your age (which you did not specify, by the way).And yes, Cefotaxime is less sensitive to the staphylococcal group of pathogens, I would choose another antibiotic if I tried to treat without determining the sensitivity to a particular bacterium.
Visitors
RELENA
Good evening! My son is 5 years old. Have pierced a cefotaxime 7 days (hurted or were ill; were sick with a scarlet fever), in day after the termination of treatment there was the strongest urticaria on all body, such late reaction to an antibiotic can be? Or is it we ate something?
Administrators
admin
RELENA, Most likely the reason is not in Cefotaxime. Such delayed adverse reactions for antibiotics are not characteristic. Probably they ate something. I also fully admit that the course of treatment with Cefotaxime could disrupt and provoke an allergic mood of the body, which subsequently resulted in urticaria, possibly on ordinary food, but such a reaction is rare. If will not pass or take place within couple of days - address to the allergist.
Guests
Lena
Hello. Tell me, please, I have this situation, I'm pregnant for 27 weeks, I got into the hospital with poisoning, I ate something wrong.At admission, there was a temperature of 38, diarrhea and 2 times vomiting, prescribed regidron, polysorbent and antibiotic cefotaxime 2 times a day intramuscularly. Also have started to prick, I when have read through the instruction, have not found, in the summary, that it or him appoint or nominate at poisonings. But the next day the temperature became normal and without diarrhea. She asked the doctor why this antibiotic was prescribed, if it is intended for the treatment of other diseases, he answered, he also helped you.
Guests
Arina
I would like to know something. I'm a girl, 16 years old. I got sick and, as it should, went to the polyclinic at the place of residence. There I was immediately sent to a teenage doctor. The doctor diagnosed ARVI, the temperature before going to the doctor was about 38.9, but it was raised only in the evening. I explained the situation and yes, one more thing, a cough does not rest, as soon as I try to breathe, cough immediately interrupt my attempt, and then I was suffocating from the approaching cough. To me have written out some, in my opinion, useless medicines and procedures, and on a raising of temperature it was recommended to drink nurofen well or ibuprofen and still have written out antibiotics "flemoxane".By the way, they did not help at all and on the third day I went with a non-decreasing temperature and a cough that does not allow me to sleep for several nights. Here to me and have written out cefotaksim, today pricked the first day, but while any improvements. I'm terribly afraid of all kinds of injections, because I always considered them very, very painful, but as for this drug, it's pretty tolerable. The doctor advised to dilute the powder with lidocaine, perhaps it makes the injection not so painful.
Visitors
rada123
Hello, we were prescribed cefotaxime 450 mg 2 times. How to dissolve with 1 g of cefotaxime and 2% lidocaine? Do I need water for injection?
Administrators
admin
rada123, 1 g of Cefotaxime for injection is dissolved in 4 ml of a solvent. The solvent is water for injection or 1% solution of lidocaine. Since you have a 2% solution of lidocaine, 1 g of Cefotaxime is diluted simultaneously in 2 ml of water for injection and in 2 ml of a 2% solution of lidocaine. We get the initial solution and type the necessary 450 mg - this will be 1.8 ml of the prepared solution. The injections of an antibiotic, judging by the dosage,I will throw out the second half of the solution and prepare a new one each time, but if the money is tight, then it is possible to store the finished solution in the refrigerator for no more than 12 hours (until the next injection).
Visitors
alekseeva2502
The doctor prescribed a child three years to prick cefotaxime three days twice (it turns out diluted drug in half). But before that, we drank augmentin 5 ml twice a day, but treatment with it was not effective, as the temperature on the 5th day rose to 38 degrees. I have a question for three days is it normal or need more? The temperature fell after the first injection somewhere in 8 hours. Now there are three injections of the temperature was no more.
Administrators
admin
alekseeva2502, I do not understand about the dosages of Cefotaxim recommended by the doctor, because they are not indicated in the question, but we will consider the medicine to be prescribed in age-related doses. It is also interesting to know if the whole problem is only in the temperature or there are still symptoms of a cold?

I would still pierce the minimum allowable course of the antibiotic, and this is 5 days to completely rid the baby of the bacterial infection.But in any case, the last word for the attending physician - he knows better.
Visitors
lepushka
The child was hospitalized for 4 years with a diagnosis of acute bronchitis and a suspicion of pneumonia, not quite clear on the description of the X-ray. Kolyat cefotaxime, already 7 days, on the 4th day of temperatures fell to 35.8, it's all cold, is there any sense in sticking further this drug, the doctor motivates continuation of the fact that the baby has a protein in the urine, can it be a side effect of the antibiotic?
Administrators
admin
lepushkaHere everything is decided by the attending physician, because the protein in the urine can be as a result of a recent cold (bronchitis, pneumonia or tonsillitis), stress, and more serious causes - pyelonephritis, glomerulonephritis, etc. If the child has problems with urine tests, the doctor must prescribe an additional urinary examination to avoid a serious complication or concomitant disease, including that caused by a primary bacterial infection (bronchitis).
Guests
lady2909
Hello, I have such a question, but if I'm stabbed with cefotaxime 2 times from angina, I was appointed for 3 days, then I can not feed the baby? Can you please explain why?
Administrators
admin
lady2909Because the antibiotic penetrates into breast milk and leads to a violation of the normal flora of the mouth and pharynx in the child. Therefore, during the injections of cefotaxime, breastfeeding should be abolished, and the resulting milk should be decanted and discarded.
Visitors
Irgash
Hello, I'm 32 years old, diagnosed with bronchopneumonia. My doctor prescribed cefotaxime 2 times a day and tavanik 500 once a day. Not many antibiotics. Day 2 dizziness and weakness.
Administrators
admin
IrgashMuch or not much can be said only by the attending physician, who has the results of your tests and lung X-rays on hand, because similar antibiotic regimens are used to treat pneumonia, bronchopneumonia of severe and moderate severity.I prefer to send such patients to a hospital, they are still not treated at home properly, but the risk of getting respiratory failure due to massive lung damage remains.
Guests
111
She stabbed the child with an injection, and he was very capricious and it so happened that the needle did not come to the end and the medicine seemed to be under the skin. Is it dangerous?
Administrators
admin
111, It is not dangerous, if there is no suppuration of the medication injected, that is, if an abscess is not formed. And this can only be known with time. If everything dissolves without remnant, then the episode can be forgotten.
Visitors
B-737
admini.e. if the normal phenomenon of temperature increase, is it shown to knock it down with a lytic mixture?
Administrators
admin
B-737, An adult in the absence of severe chronic illnesses can tolerate temperatures of up to 38 degrees Celsius. Less than this indicator to use the means to reduce it, I think it's pointless - it blocks the immune response of the body and the production of human interferons that fight viruses.True, the temperature threshold for all people is different and some of the 37.5 feel extremely bad, such people can lower the temperature and on smaller figures. In this regard, everything is individual.

And at the beginning of treatment with antibiotics, the temperature may rise (this phenomenon is called the Yarisch-Gerxheimer reaction and is described in the literature). Tactics are the same as with increasing temperature as a result of the development of an infectious or inflammatory process.
Visitors
Novak_2016
I have bilateral pneumonia. I am being treated at home. Have registered Cefotaxime in / m. Today is the third day as stabbing injections, there are notable improvements, but the problem has appeared. Something is happening in my head, some unpleasant sensations, similar to the fact that consciousness disconnects. They last a second, but often. What is it and will it not be worse? After all, I have to stab him two more times for three.
Administrators
admin
Novak_2016, Similar side effects when using this antibiotic are unknown to me neither from experience, nor from the instruction (there is dizziness, but not switching-off).Either this is a manifestation of the underlying disease, or an individual reaction to Cefotaxime, since I can not pinpoint this definitely, I can not advise you to consult a doctor who prescribes this medicine.
Visitors
Tanja
Hello. Have appointed a preparation to the child of 8 years, weight approximately 25 kg. From fear of pricking, I forgot to stab 1 ml or 1 gram (the whole ampoule) of the drug? Dilute in 4 ml of lidocaine. Help me please.
Administrators
admin
Tanja, According to calculations, 1 ml does not work for me - either more than 1 ml, or a gram of chop, but this is the maximum limit dosage for a child weighing 25 kg. According to the instructions it goes like this: "Children weighing less than 50 kg - intravenously or intramuscularly (children over the age of 2.5 years) 50-180 mg / kg in 4-6 introductions." And a specific dose of antibiotic from this fork of doses is determined by the attending physician in accordance with the condition and severity of the disease in the patient.
Visitors
lancetti
Good day. The drug is really very good. We treat them not the first time. Treatment is faster.The youngest child (almost 3 years) prescribed this antibiotic in February from bronchitis. With the reservation - pour 5 ml of novocaine into the vial, and do an injection of only 2 ml. Twice a day. Also, the doctor explained that the remaining divorced medicine should be thrown away. One of these days has picked up the son a pneumonia. And again prescribe this antibiotic. The dosage is the same as before. But now the doctor (already different) has told or said, that it is possible to not throw out the remained medicine, and to prick another time. Tell me who is right?
Administrators
admin
lancetti, I always advise you to throw it away. Still, injectable drugs and if God forbid which wand gets into the diluted ampoule, the abscess on the pope is the smallest that can wait for the child. Especially with children, I do not risk secondary drugs. So you want to put experiments on your children - colitis with an old dilution, you want to safely undergo a course of injections - colitis with a freshly prepared solution, and discard the rest.

The money issue also takes place, it is better to go through a full course of antibiotic therapy than to finish it prematurely due to lack of funds, but this is no longer to Cefotaxime, but to expensive drugs refers.
Visitors
lancetti
admin, Thank you.
Visitors
sikopa
Good afternoon! To the child of 7 years, have appointed or nominated cefotaksim, diluted with water. The child screams in pain and is afraid to go to the injection. When the doctor asked whether it was possible to refuse with an anesthetic. Question: when diluted with anesthetic, the quality of the drug worsens?
Administrators
admin
sikopa, To dilute Cefotaxime and reduce pain, you can use a special injection 1% solution of lidocaine. The breeding scheme is similar to the breeding of Ceftriaxone (preparations of one pharmacological group), and how to properly dilute the latter I wrote in a detailed article that can be found through the search form of the Directory.
Visitors
Alina K.
Hello, have appointed or nominated a cefotaxime at a genyantritis 2 times a day 7 days, on the second day there was a strong cough with a departure of dark green sputum, it is very sick to cough ... But green allocation from a nose have decreased. The fact that a cough appeared does not mean that the antibiotic is misdirected and the disease has started to progress?
Administrators
admin
Alina K.Dark green sputum is bad. Especially if it eventually comes not from the nose, but from the deep divisions of the respiratory tract. Address to the attending physician, let will direct on a picture of a thorax if after inspection will understand that the sputum goes therefrom. Or he already will redirect you to the ENT, if this is in his part and the pus comes out of the sinuses.
Guests
Alesya Novoselova
To effectively use both cefotaxime and all cephalosporin antibiotics in general, it is necessary to use 1% lidocaine, this concentration of the drug provides high safety and effectiveness of antibiotic use. Lidocaine is a powerful second-generation analgesic, therefore, in addition to its properties as a solvent for antibiotics, it has a powerful analgesic effect. Novocaine should not be used as a solvent, since its use spectrum is sufficiently narrow and as a solvent according to its instructions, it is not used, but is used only privately for anesthetic small-scale interventions. Lidocaine has long been known in clinical practice, so its safety should not be questioned.It should be taken into account that lidocaine has contraindications to use in patients with cardiovascular diseases and in pregnant women at any gestation period. Before use, consult your physician to prevent individual intolerance to the drug components. All the best!
Guests
Lyudmila Musaeva
My husband and I had an acute intestinal infection after taking a low-quality kefir. Have appointed Cefotaxime. And nowhere about this do not write. Maybe it's wrong !? Kohl 2 days.
Administrators
admin
Lyudmila Musaeva, In intestinal infections (I think there is a suspicion of salmonellosis in your case) it is permissible to use antibiotics, such as Cefotaxime. If this drug is prescribed by a doctor - take the prescribed treatment.
Visitors
Alyoshechka
To the child of 12 years. We took the analysis from the nose for staphylococcus, we sowed staphylococcus aureus 10 * 9. Have made sensitivity and there has shown, that to him approaches or suits cefotaxime.How many days it is necessary to prick it with such a diagnosis. The child has severe nausea and diarrhea, injections are given 2 days - in the morning and in the evening.
Administrators
admin
AlyoshechkaThe question is not clear. Write a clinic, symptoms. What with the fact that the child found staphylococcus aureus? He is not allowed into kindergarten or what? A lot of people live with an obligate microflora, they sow monstrous titres of microbes, but patients feel themselves normally, do not get sick, they do not suffer from immunity. Why load a child with antibiotics. Treat illnesses, not flora.
Guests
PurumBurum
Such a question, after one injection of cefotaxime, the drug was canceled, after what time can you drink alcohol in such a case, without the risk that the antibiotic and alcohol will cause a strong impact on the body? belay
Administrators
admin
PurumBurum, The half-life of the drug Cefotaxime is about 2-4 hours. That is, on the next day after use, the body is completely free from the metabolites of the antibiotic.And alcohol is harmful, although with antibiotics, even without.
Visitors
Diana_Sharanina
Hello. At me such problem was ill with a bronchitis, it was treated all over again independently azithromycin 1 3 times a day (has not helped or assisted) has gone to the doctor. The doctor prescribed clarithromycin 2 r daily, ambroxol, a little better, but then the temperature rose again to 37 degrees. I changed my doctor, went to another one, she prescribed me injections of ceftriaxone 2 injections a day (7 days), today is 7 days, there is improvement in terms of temperature, there is no cough, but there is a terrible weakness, I can not even sit constantly want to lie and sleep there was a noise in the ears, then passes it appears). Fluorography 2 times did in the picture, pneumonia was not shown, the doctor listened, said wheeze still there, and on the fluorography the lung pattern is strengthened due to the bronchial component, as there was nothing in LOR for her part, but weakness is excruciating and I feel as if there is temperature, and ears heavily laid. Also, after interruptions after clarithromycin, I took a blood and urine test, showed the doctors, said that inflammation was not visible, the only anemia was 111, what should I do now? Help,please, every day worse and worse, maybe I did not get the antibiotic? Can change the other? Analysis for sensitivity is still early, you need 2 weeks to wait, and I already so exhausted the body. Help me please!
Administrators
admin
Diana_Sharanina, There are two options. If bronchitis (temperature, inflammation) symptoms are gone, it is quite possible to spend on drink a course of vitamins (preferably with iron due to unclear anemia) and consume plenty of fluids (tea, water, juice). Residual cough (you can optionally continue to receive Ambroxol), headache, somnolence must eventually pass (if these symptoms are not caused by anemia, but anemia will understand later, after a couple of weeks after complete recovery from bronchitis, hand re-test to check the level of hemoglobin , maybe after the illness his level jumped down).

If symptoms of bronchitis persists, then shows a further antibiotic treatment, only need to use drugs other groups not previously used in the treatment, plus add physiotherapy (UHF, and other techniques, appoint a physiotherapist).Cefotaxime is not needed, because it is with Ceftriaxone a drug of one group (cephalosporins of the 3rd generation) and there is no sense in using the same medicine in this case.

Sowing with sensitivity to you to do or make already late, and I see faster convalescence on the description of illness or disease, rather than blooming bronchitis, therefore this analysis now superfluous.
Guests
Inga
Hello. Tell me please. We had a fever yesterday morning. The doctor said that it was sore throat and prescribed to prick the cifatoxin 2 times a day. We pierced the day, today there are no signs of angina. Can it stop stabbing it and transfer it to liquid antibiotic Amoxicillin?
Administrators
admin
Inga, No, so no one does, it is permissible only if the antibiotic is not suitable and an urgent replacement of the drug is needed. Kolit Cefotaxime according to the proposed scheme at least 5 days, but rather as much as prescribed by your doctor.
Visitors
Timur's mother
To the son 3 years.The nose is stuffy, can not breathe, but there's no rhinitis. Throat is red, swollen with a white touch. The temperature rose on the third day - 38.3. Urine analysis is good, in the blood monocytes 16, lymphocytes 59, leukocytes 12.2, segment-nuclear 18, stab. 5. After raising the temperature, the doctor prescribed Cefotaxime injections on Lidocaine twice a day, at the reception after 2 days. In addition, rinsing of the nose with sea water, irrigation of the throat with Ingaliptum and Septomirin, drops of Tonzylgon + antihistamines are also prescribed. Whether this treatment will be effective provided that the smear from the nose and mouth was not taken from the son. Will it help breathe through the nose and remove the swelling of the throat?
Administrators
admin
Timur's mother, Inflammation in the body is present, what the tests say, though not strong. There are raids on the throat, if it is not diphtheria (you can exclude it provided that the child receives all the necessary vaccinations on the calendar), then, most likely, angina, so treatment with antibiotics is justified.

Runny nose is unclear from what. In this case, the ENT doctor must give his opinion after examining the child, the cause may not be associated with angina (adenoids and others).In the rest, I do not seem to see any flaws in treatment, get well and recover.
Visitors
Timur's mother
The rhinitis is not present, simply the nose is put in pawn strongly. So much that when you try to breathe through your nose you get the strongest snoring. The child is not vaccinated against diphtheria. The adenoids are enlarged, ENT said that while surgery is not required. Now because of the temperature show the child Laura no opportunity.
Administrators
admin
Timur's motherThen, it remains to treat the angina and then show LOR if the problem with nasal breathing persists.
Guests
Millyula
Diagnosis: right-sided lower-lobe pneumonia. Have written out this antibiotic, teotard and stolid. Today is the second day. The temperature and really the second day does not rise. Cough was less frequent. But by the evening there is a very strong throbbing headache. At which even a very rare cough becomes a torment ...
Guests
Maria2020
I almost understood, it is written above that it was incorrectly bred. Water for injection + lidocaine is all 2 ml. That is 4 ml in a tube ... I breed so! Why is this wrong? And how right?
Administrators
admin
Maria2020, Properly dilute, provided that lidocaine is 2%, and not a special 1% injection. Where it is said that it is wrong? Twice I revised it, I did not see it ...
Guests
Irbe
When can I drink alcohol after a week of intramuscular cefotaxime?
Administrators
admin
IrbeA similar question was already asked and the answer was received. Carefully look at my answers above.
Visitors
Aiven
Hello. The wife lies in the hospital with a diagnosis of "Fracture of the base of the skull." Without complications. Prescribed a preventive course of cefotaxime 2 times a day for 5 days. During the injections, the temperature was 37.4, which, as I understood, is normal. But the next day after the end of the course, the temperature jumped to 38. Is this normal? Before the doctor on duty can not get through, the weekend.
Administrators
admin
AivenIf there are no signs of infection, then the brain produces such pyrogenic or temperature reactions in response to its damage. And Cefotaxime has nothing to do with it. This happens after accidents and without colds and bacterial diseases. And it's normal or not, everything depends on the specific case, you will not be told the truth in the hospital, unfortunately.
Visitors
inns
Hello! After the introduction of the drug intramuscularly, I became covered with a sticky sweat, a weak pulse and a brief loss of consciousness ... What could it be? Sugar fell, so the doctor said.
Administrators
admin
innsIt looks like an allergic reaction, which can be provoked by intramuscular injections of antibiotics. I would replace the cefotaxime with another doctor on the spot of the doctor because of the suspicion of anaphylactoid reactions. About sugar, most likely the doctor has thought up, anything such is not usually observed, even at sick of a diabetes.
Visitors
Diana5445
Hello. To me, Laur appointed Cefotaxime to drip into the nose 2 times a day. Could there be an allergy in the form of Quincke's edema when dripping into the nose?
Administrators
admin
Diana5445, Cefotaxime is an injectable antibiotic that is used intravenously or intramuscularly, but not locally, as the otorhinolaryngologist has prescribed. It is not right. The antibiotic should still be absorbed into the bloodstream to start working. I advise you to go to another doctor for an appointment of competent treatment.
Visitors
Anechka
To my son 1.4. He was prescribed cefotaxime 400 mg 2 times. I dilute it with 2% lidocaine 2 ml and 2 ml water for injection. How much will 400 mg be in the syringe? How much should I prick?

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