Bromhexine - instructions for use, reviews, analogs and formulations (4 mg tablets and 8 mg Berlin Chemie, syrup, solution) drug for cough treatment in adults, children and during pregnancy

In this article, you can read the instructions for using the drug Bromhexine. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Bromhexine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Bromhexine in the presence of existing structural analogs. Use to treat cough, including dry with bronchitis and asthma in adults, children, as well as during pregnancy and lactation.

Bromhexine - mucolytic agent with expectorant action. Reduces the viscosity of bronchial secretions by depolarizing the acidic polysaccharides contained in it and stimulating the secretory cells of the bronchial mucosa that produce a secret containing neutral polysaccharides. It is believed that bromhexine contributes to the formation of surfactant.

Pharmacokinetics

Bromhexine is rapidly absorbed from the digestive tract and is subject to intensive metabolism during the "first passage" through the liver. Widely distributed in the tissues of the body. About 85-90% is excreted in the urine mainly in the form of metabolites. The metabolite of bromhexine is ambroxol. Bromhexine penetrates the BBB. In small quantities, it penetrates the placental barrier.

Indications

Diseases of the respiratory tract, accompanied by the formation of a difficult-to-separate viscous secretion:

• tracheobronchitis;
• chronic bronchitis with broncho-obstructive component;
• bronchial asthma;
• cystic fibrosis;
• chronic pneumonia.

Forms of release

Tablets 4 mg and 8 mg (Berlin Chemie).

Syrup (child form of the drug).

Solution for oral administration.

Solution for injection (Bromgexin Aegis).

Instructions for use and reception scheme

Inside adults and children older than 10 years - 8 mg 3-4 times a day. Children under 2 years - 2 mg 3 times a day; at the age of 2 to 6 years - 4 mg 3 times a day; at the age of 6 to 10 years - 6-8 mg 3 times a day. If necessary, the dose can be increased to 16 mg adults 4 times a day, children - up to 16 mg 2 times a day.

In the form of inhalation to adults - 8 mg, children over 10 years - 4 mg, at the age of 6-10 years - 2 mg. At the age of 6 years - apply in doses up to 2 mg. Inhalation is carried out 2 times a day.

Therapeutic effect may appear on the 4-6th day of treatment.

Parenteral administration is recommended for treatment in severe cases, and also in the postoperative period to prevent congestion of thick sputum in the bronchi. Enter 2 mg subcutaneously, intramuscularly or intravenously 2-3 times a day slowly for 2-3 minutes.

Side effect

• dyspeptic phenomena;
• headache;
• dizziness;
• increased sweating;
• skin rash;
• cough;
• bronchospasm.

Contraindications

• hypersensitivity to bromhexine.

Application in pregnancy and lactation

In pregnancy and lactation, bromhexine is used in cases where the intended benefit to the mother exceeds the potential risk to the fetus or child.

special instructions

With peptic ulcer disease, as well as when indicating gastric bleeding in an anamnesis, bromhexine should be administered under the supervision of a physician.

Use with caution in patients suffering from bronchial asthma.

Bromhexine is not used concomitantly with drugs containing codeine, because this makes it difficult to cough up thinned phlegm.

Applied as a combination of herbal preparations with essential oils (including eucalyptus oil, anise oil, peppermint oil, menthol).

Drug Interactions

Bromhexine is incompatible with alkaline solutions.

Analogues of the drug Bromhexine

Structural analogs for the active substance:

• Bromhexine 4 Berlin-Chemie;
• Bromhexine 4 mg for;
• Bromhexine 8;
• Bromhexine 8 Berlin-Chemie;
• Bromhexine 8 mg;
• Bromhexine Grindex;
• Bromhexine MS;
• Bromhexine Nycomed;
• Bromhexine-Acry;
• Bromhexine-ratopharm;
• Bromhexin-Rusfar;
• Bromhexine-UBF;
• Bromhexine-Ferein;
• Bromhexine-Aegis;
• Bromhexine hydrochloride;
• Bronchotil;
• Vero-Bromhexine;
• Solvyn;
• Flegamine;
• Flexin.

Similar medicines:

Other medicines: