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Pirentel - instructions for use, reviews, analogs and forms of release (tablets 250 mg, suspension or syrup) drugs for the treatment of worms in adults, children and pregnancy

Pirentel - instructions for use, reviews, analogs and forms of release (tablets 250 mg, suspension or syrup) drugs for the treatment of worms in adults, children and pregnancy

In this article, you can read the instructions for using the drug Pirantele. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Pirantel in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Pirantel in the presence of existing structural analogues. Use for the treatment of worms (ascariasis, enterobiasis and other pathogens) in adults, children, as well as during pregnancy and lactation.

 

Pirantele - anthelminthic agent acting on nematodes.

 

It causes neuromuscular blockade in sensitive helminths, which facilitates their removal from the digestive tract without stimulation and stimulation of migration of affected worms.

 

The drug acts on parasites in the early phase of development and on their mature forms, does not affect the larvae during their migration into tissues.

 

Pirantel is effective against infestations caused by pinworms (Enterobius vermicularis), hookworms (Ancylostoma doudenale, Necator americanus), against the causative agents of trichocephalosis (Trichostrongylus orientalis and Trichostrongylus colubriformis) and ascariasis (Ascaris lumbricoides).

 

Pharmacokinetics

 

Pirantel is very poorly absorbed from the gastrointestinal tract (GIT). There are no data on the penetration of the drug through the placenta and into the milk of the lactating woman, and also regarding the distribution of the drug in the tissues and body fluids (theoretically, the resorption of the drug is minimal). About 93% of the oral dose of the drug is excreted unchanged in the intestine, and not more than 7% by the kidneys in unchanged form or as a metabolite of N-methyl-1,3-propanediamine.

 

Indications

  • ascaridosis;
  • enterobiosis;
  • ankylostomidosis;
  • necropsy;
  • trichocephalus.

 

Forms of release

 

Tablets 250 mg.

 

Suspension for oral administration (sometimes mistakenly referred to as syrup).

 

Instructions for use and dosage

 

Inside.

 

The drug is used during or after a meal, thoroughly chewing the tablet, drinking 1 glass of water.

 

If no other treatment regimen is prescribed, depending on the age and body weight of the patient, the following dosages are recommended (tablets and suspension):

  1. 3-6 years - 1 tablet once a day - 1 measurement = 5 ml;
  2. 6-12 years - 2 tablets once a day - 2 measures = 10 ml;
  3. over 12 years and adults with body weight up to 75 kg - 3 tablets once a day - 3 measures = 15 ml;
  4. adults with a body weight of more than 75 kg - 4 tablets once a day - 4 measures = 20 ml.

 

To avoid self-invasion, it is possible to repeat the course 3 weeks after the first dose.

 

With isolated ascariasis, the use of Pirantel is recommended at 5 mg / kg, once.

 

With ascariasis and enterobiasis, as well as mixed infestations with these parasites, the dose intended for the entire course (at the rate of 10 mg / kg) is applied once.

 

With ankylostomiasis, a combination of non-carotenosis with ascariasis or other combined helminthic lesions, Pirantel is used for 3 days at 10 mg / kg per day.

 

In massive invasions of Necator americanus, a dose of 20 mg / kg of body weight is recommended for 2 days.

 

Side effect

  • nausea, vomiting;
  • lack of appetite;
  • diarrhea;
  • pain and cramping of the stomach;
  • headache;
  • dizziness;
  • drowsiness or insomnia;
  • weakness;
  • rash;
  • elevated temperature;
  • hearing impairment;
  • hallucinations with confusion and paresthesia (the relationship of these symptoms with taking the drug is not proven).

 

Contraindications

  • hypersensitivity to the drug;
  • myasthenia gravis (treatment period);
  • Children under 3 years old (for this dosage form).

 

Application in pregnancy and lactation

 

There are no controlled studies of the use of Pirantel in pregnant women, so the drug should be used only if the potential benefit to the mother exceeds the possible risk to the fetus.

 

There are no data on the safety of the drug in lactating women, so the question of stopping breastfeeding for the duration of treatment with the drug should be resolved.

 

special instructions

 

After taking Pirantel laxatives are not prescribed. In the treatment of enterobiasis, all co-residents must be treated simultaneously. Careful hygiene (cleaning the living quarters and cleaning clothes to destroy helminth eggs) serves as a preventive measure against reinfection.14 days after treatment with Pirantel, parasitological control tests should be performed.

 

Given the possible side effects of the nervous system during the use of the drug should be careful when dealing with potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

 

Drug Interactions

 

Pyrantel should not be used together with piperazine. These funds act antagonistically.

 

Pirantel increases the concentration of theophylline in plasma.

 

Analogues of the drug Pirantel

 

Structural analogs for the active substance:

  • Helmintox;
  • Nemocide;
  • Pirantela pamoat.

 

Analogues on the antihelminthic effect:

  • Biltricide;
  • Vermox;
  • Vero-Mebendazole;
  • Worming;
  • Gelmodol-VM;
  • Decaris;
  • A thousand-thousandth grass;
  • Mebendazole;
  • Medamin tablets 0.1 g;
  • Nemosol;
  • Tansy flowers;
  • Piperazine;
  • Piperazine adipate;
  • Piervinium;
  • Sanoxal;
  • Telmox 100;
  • Pumpkin seeds.

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Reviews (26):
Guests
ollo
In the house there are two dogs and a cat, a little child has appeared, so the problem of fighting worms became urgent, as children put all sorts of muck and unwashed hands into their mouths.First tried to drive worms Dekarisom, my mother's old remedy (she also advised) drank the whole course, but when they passed the analysis of the stool after the treatment course they still found worms. I had to buy Pirantel and there were no misfires, with another surrender the body was clean. So now we use Pirantel, if a similar problem appears.
Guests
Lech
Shoot two dogs and a cat living in the house, or let them devour the poison, and do not have to poison the baby.
Guests
Ksenia
Pinworms, for example, do not live in dogs, dogs carry them from one person to another)) why should they be targeted if we pass them their infection)), they can also be processed easier)
Guests
Christina
Lech, shoot yourself better if you do not understand the treatment.
Guests
Crown
Animal glistens are not transmitted to humans.
Administrators
admin
Crown, Ascarids are accurately transmitted. It is possible that there are others, but I'm not strong in veterinary medicine. Although as for me and ascarid enough.
Guests
May
Yeah, we are waiting for a response about the medicine, but we get reflections on the ways of transferring worms or screaming of the lusters. Class.
Administrators
admin
May, Be the first. And then the advisers are now a dime a dozen smile
Guests
Saltanat
My daughter bites her nails from a small age. Once the doctor prescribed a pyrantel. It helps.
Guests
Nika
Shoot, of course, is not necessary, but in a house where there is a small child to keep dogs or cats is not very good.
Guests
Yulechka
Glistov can be on the playground, and in the sandbox, etc. pick up, not just dogs and cats :)
Guests
Alex84
And I agree with Lyokha. I would shoot both cats and dogs, so as not to poison the child. And infestations from animals are very much transmitted to humans.Ascarids, Ankylostomas, Nematodes (pinworms) are also a common type of worms in cats and dogs, Toxocara, Cucumber tapeworm, Broad Ribbon, Cestodes, Flukes ... I think this is enough to reflect on who you are dearer to a child or pets. .. Source: knowledge obtained at the Medical Academy.
Guests
helen
I really love animals, but my children are more. When I see that the small stomach in the middle of the navel is sore, and the older one has frequent urination. Already on the symptoms I assume that it's worms. Also I start to think what to give to children, what tablets. And there are so many side effects and you are afraid to give them. And already I begin to regret that I started a dog. There would be no dog, there would be no problems. But I start to remember, when we did not have a dog, the children were not always climbed out of the sandbox in the summer and after the summer they started itching in the anus. So here is a double-edged sword. Not having a dog you can get anywhere, worms live in the ground, and in the soil, etc. All people need 2 times a year to take drugs from the worms necessarily.
Guests
lef
I accepted it myself for prophylaxis.It's bad that you need to chew - such a muck! Nearly did not vomit. Fu!
Guests
Irina
We did not have any animals, and our daughter had to be treated for Ascaris. Worms are a disease of dirty hands!
Guests
Laka
I took 2 times during pregnancy for fear and risk and thank God it was all right.
Guests
Milan
Does it help with pinworms?
Administrators
admin
Milan, Pinworms or Enterobius vermicularis are successfully treatable with the Pirantel drug. For the appointment of an exact therapy scheme, I advise you to consult your doctor.
Guests
Lyalya
Pirentel is a good thing. It is good to drink for prophylaxis. To the farmers! I advise you to drink green tea. From the inflammation of the brain. Worms are not from dogs and cats, but from dirt. If you are dirty, it is not treated with any pyrantel.
Guests
Aigerim
How many days should I take 2 tablets. The child is 9 years old.
Administrators
admin
Aigerim, Register as prescribed by the rules of the Directory and clarify the question, because the disease, for which treatment the child will give Pirantel, is not indicated. In general, the exhaustive information is in the manual, you just need to read it carefully, but it is better to follow the recommendations of the treating doctor.
Guests
Teke
My son had worms, infected the whole family. I've drunk Pirentel. I wait for analyzes. It seems to move in the pope gone.
Guests
Olga
About 8 years ago we did not have animals, but the child found worms. Treated the whole family pirantelom, on the advice of a doctor.
Guests
grandmother of Rome
A good drug. In liquid form, they gave the grandson (3 years) 5 ml from the Askaris, at 9 pm. On day 3 (3 chairs) left dead creatures, big and small brrrr! Prior to this, according to the doctors' advice, nemozol was given 3 times 20 ml each with interruptions of 3-4 weeks (the entire vial, the adult dose). Did not help, in the analysis every time there were eggs. In vain we poisoned the child. Has helped with 1 time pirantel. It's easy to drink, I think I also need to drink a suspension.
Guests
Vera .
I have three cats at home, and never had problems with worms. Just keep the animals clean and observe the rules of personal hygiene.
Guests
Ekaterina Aleksandrovna
I have three children, and I give everyone a pirantel. The only thing, at all three, after reception of a medicine a liquid chair within one day and all. I'm happy with the result. Thanks to the manufacturer.

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