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Zirtek - instructions for use, analogs, reviews and release forms (10 mg tablets, drops) of a medicinal product for the treatment of allergies and skin rashes (urticaria, dermatitis) in adults, children (including newborns) and pregnancy

Zirtek - instructions for use, analogs, reviews and release forms (10 mg tablets, drops) of a medicinal product for the treatment of allergies and skin rashes (urticaria, dermatitis) in adults, children (including newborns) and pregnancy

In this article, you can read the instructions for using the drug Zirtek. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Zirtek in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Zirtek in the presence of existing structural analogs.Use to treat allergies and skin rashes (urticaria, dermatitis) in adults, children (including newborns), as well as during pregnancy and lactation.

 

Zirtek - antiallergic drug. The blocker of histamine H1 receptors, a competitive histamine antagonist, a metabolite of hydroxyzine. Prevents development and facilitates the course of allergic reactions, has antipruritic and antiexudative action.

 

Affects the early histamine-dependent stage of allergic reactions, limits the release of inflammatory mediators in the late stage of the allergic reaction, reduces the migration of eosinophils, neutrophils and basophils, stabilizes the membranes of mast cells. Reduces the permeability of capillaries, prevents the development of edema of tissues, relieves spasm of smooth muscles. Eliminates the skin reaction to the administration of histamine, specific allergens, and also to cooling (with "cold" urticaria). Reduces histamine-induced bronchoconstriction in bronchial asthma of mild course.

 

Virtually no anticholinergic and antiserotonin action. In therapeutic doses, it practically does not have a sedative effect.

 

After a single dose of Cetirizine at a dose of 10 mg, the onset of the effect is observed after 20 minutes (in 50% of patients) and after 60 minutes (in 95% of patients), the effect lasts more than 24 hours. Against the background of course treatment, tolerance to antihistamine action of cetirizine does not develop. After cessation of treatment, the effect lasts up to 3 days.

 

Pharmacokinetics

 

After ingestion, the drug is quickly and completely absorbed from the digestive tract. The intake of the drug with food does not affect the amount of absorption. When taking the drug at a dose of 10 mg for 10 days cumulation of cetirizine is not observed. Approximately 2/3 of the dose is excreted by the kidneys unchanged.

 

Indications

  • treatment of symptoms of year-round and seasonal allergic rhinitis and allergic conjunctivitis such as itching, sneezing, rhinorrhea, lacrimation, congestion hyperemia;
  • hay fever (hay fever);
  • urticaria (including chronic idiopathic urticaria);
  • angioedema;
  • other allergic dermatoses (including atopic dermatitis), accompanied by itching and rashes.

 

Forms of release

 

Tablets, film-coated 10 mg.

 

Drops for oral administration (a convenient pediatric form of the drug).

 

Instructions for use and dosage

 

The drug is prescribed inside.

 

Adults and children over 6 years of age are prescribed a dose of 10 mg (1 tablet or 20 drops) per day. Adults - 10 mg once a day; children - 5 mg twice a day or 10 mg once a day. Sometimes an initial dose of 5 mg may be sufficient to achieve a therapeutic effect.

 

Children aged 2 to 6 years are prescribed 2.5 mg (5 drops) 2 times a day or 5 mg (10 drops) once a day.

 

Children aged 1 to 2 years are prescribed 2.5 mg (5 drops) up to 2 times a day.

 

Children aged 6 months to 12 months are prescribed 2.5 mg (5 drops) once a day.

 

Side effect

  • thrombocytopenia;
  • drowsiness;
  • dizziness;
  • headache;
  • aggression;
  • excitation;
  • depression;
  • hallucinations;
  • insomnia;
  • teak;
  • convulsions;
  • fainting;
  • tremor;
  • violation of accommodation;
  • blurred vision;
  • nystagmus;
  • tachycardia;
  • rhinitis;
  • pharyngitis;
  • dry mouth;
  • nausea;
  • stomach ache;
  • diarrhea;
  • upset urination;
  • enuresis;
  • itching;
  • rash;
  • hives;
  • angioedema;
  • hypersensitivity, up to the development of anaphylactic shock;
  • increase in body weight;
  • fatigue;
  • asthenia;
  • edema.

 

Contraindications

  • terminal stage of renal failure (CC <10 ml / min);
  • pregnancy;
  • lactation period (breastfeeding);
  • hereditary intolerance to galactose, a lack of lactase or a syndrome of glucose-galactose malabsorption;
  • children under 6 years (for tablets);
  • Children under 6 months of age (for drops) (contraindicated in newborns);
  • hypersensitivity to the components of the drug;
  • hypersensitivity to hydroxyzine.

 

Application in pregnancy and lactation

 

The drug is contraindicated for use in pregnancy and lactation (breastfeeding).

 

special instructions

 

Children aged 6 months to 6 years of age Zirtek prescribed in the form of a drug for oral administration of 10 mg / ml.

 

Impact on the ability to drive vehicles and manage mechanisms

 

With an objective assessment of the ability to drive vehicles and manage mechanisms, there were no undesirable reactions detected when taking the drug at the recommended dose. But, nevertheless, during the period of taking the drug, it is advisable to refrain from engaging in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

 

Drug Interactions

 

In the study of the drug interaction of cetirizine with pseudoephedrine, cimetidine, ketoconazole, erythromycin, azithromycin, glipizide and diazepam, no clinically significant undesirable interaction was detected.

 

With simultaneous appointment with theophylline (400 mg per day), the total clearance of cetirizine is reduced by 16% (theophylline kinetics do not change).

 

With simultaneous administration with macrolides and ketoconazole, there were no changes on the ECG.

 

When using the drug in therapeutic doses of data on the interaction with alcohol (at a blood alcohol concentration of 0.5 g / l) is not obtained. Nevertheless, the patient should refrain from drinking alcohol during therapy with the drug in order to avoid oppression of the CNS.

 

Analogues of the drug Zirtek

 

Structural analogs for the active substance:

  • Alerza;
  • Allertec;
  • Zincet;
  • Zodak;
  • Lethisen;
  • Parliamentary;
  • Cetirizine;
  • Cetirizine HEXAL;
  • Cetirizine DS;
  • Cetirizine-Teva;
  • Cetirizine dihydrochloride;
  • Cetirinax;
  • Cetrin.

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Reviews (7):
Guests
Liuba
Zirtek or Zodak (this is one and the same) is certainly a good medicine, which helps very well from, in our case, atopic dermatitis in my son was given. But if the active ingredient Cetirizine is the same, then why can not you take the usual Cetirizine in the pharmacy, which is 5 times cheaper than the foreign Zirtek at a price. What was done by me and what I do not regret, because it helps the domestic drug is not worse than imported, and the budget is saved.
Visitors
Ariel
I'm sorry of course, but Zirtek and Zodak are not the same. Zirtek is the original drug, and Zodak generic on its basis. And despite the fact that they are considered analogs - they are different. Original drugs are better. There is a concept of bioequivalence, the point is that the generic is not bioequivalent to the original. All clinical studies were conducted according to the original, and not on a copy. The generic may have different isomerism, different auxiliary substances in the composition, hence different pharmacokinetics, etc. In any case, the original is better studied!
And then as for cetirizine, it's like in the case of nosh and drohotertin, for example, for me drhotertine does not help itself in any way, but yes-yes!
Guests
Alya
I also agree with Ariel that there are a lot of analogues of medicines for active active substance, but I myself repeatedly convinced that generics, very often act not equal to the original, so I prefer the original. And the fact that the medicine worked well, it only proves that even the generic works well, what to say about the original. I, for one, are very pleased with Zirtek, because, by the will of fate, I often suffer from allergies.
Guests
Mila
A good medicine and it does not matter how many at it now analogs and help they to whom or not. Always carry a zirtek in my purse. I'm allergic to egg powder and citrus fruits and no matter how hard I try, but still meet with these products, I'll eat a bun with chemistry or with zest and all just swell and start swelling, and my eyes become numb, I'll immediately drink the tablet as soon as I feel something I do not even know what I would have done without him.
Guests
Margarita82
I give Zirtek his little son, he suffers from an allergy. Generics prefer not to give the child, so as not to save on his health.The original drug is produced according to strict standards, proven auxiliary substances are used, the necessary studies were carried out on it. Zirtek completely suits me, quickly removes allergy attacks, did not observe drowsiness in the child.
Guests
Valeria80
Valeria80, You are a warning for the hidden advertising of the drug Zirtek. I'll catch it again - I'll put it on the blacklist.
admin
Guests
Veramurulida
Only Zirtek! None of the analogs has such an effect.
I apply for all kinds of allergy. There is no addiction. The effect after 15-20 minutes. I give it to my children from birth according to the calculation 1 drop per 2 kg of weight. I took it during pregnancy and during breastfeeding, when the body itself could not cope with the attacks. Unlike other drugs, it is effective and completely eliminated from the body. Sedation has no effect at all.

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