Lamisil - instructions for use, analogs, testimonials and release forms (tablets 250 mg, cream or ointment 1%, spray 1%, Uno solution, gel 1% Dermgel) for the treatment of mycosis (fungus) of feet and nails and hair loss in adults, children and pregnancy

In this article, you can read the instructions for using the drug Lamisil. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Lamizil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Lamizil in the presence of existing structural analogs. Use for treatment of mycosis (fungus) of feet and nails and multi-colored hair loss in adults, children, as well as during pregnancy and lactation.

Lamisil - an antifungal drug for external use, which has a wide range of antifungal activity. In small concentrations, Terbinafine (the active ingredient of Lamisil) has a fungicidal effect against dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton violaceum, Trychophyton tonsurans, Microsporum canis, Epidermophyton floccosum), mold (mainly Candida albicans) and some dimorphic fungi (Pityrosporum orbiculare). Activity with respect to yeast fungi, depending on their type, may be fungicidal or fungistatic.

Terbinafine specifically changes the early stage of biosynthesis of sterols occurring in fungi. This leads to a deficit of ergosterol and to intracellular accumulation of squalene, which causes death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.

Terbinafine has no effect on the cytochrome P450 system in humans and, accordingly, on the metabolism of hormones or other medications.

Pharmacokinetics

With external application absorbed less than 5% of the dose, so the absorption of terbinafine in the systemic blood stream is extremely low.

Indications

Prevention and treatment of fungal infections of the skin:

• mycosis stop (tinea pedis), inguinal epidermophytia (tinea craris), fungal lesions of smooth skin of the body (tinea corporis), caused by such dermatophytes as Trichophyton (including T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum canis and Epidermophyton floccosum;
• yeast infections of the skin, mainly those caused by fungi of the genus Candida (eg, Candida albicans), in particular, diaper rash;
• a multicolored lichen (Pityriasis versicolor), caused by Pityrosporum orbiculare (Malassezia furfur).

Forms of release

Tablets 250 mg.

Spray for external use 1%.

Cream for external use 1% (sometimes mistakenly called ointment).

Solution for external use film-forming 1% Lamisil Uno.

Gel for external use 1% Lamizil Dermgel.

Instructions for use and how to use them

Cream or ointment

In adults and children over 12 years of age, Lamisil can be used 1 or 2 times a day, depending on the indications. Before using the drug, it is necessary to thoroughly clean and dry the affected areas. The cream is applied a thin layer on the affected skin and adjacent areas and lightly rubbed. In infections accompanied by intertrigo (under the mammary glands, in the interdigital spaces, between the buttocks, in the groin area), the places of application of the cream can be covered with gauze, especially at night.

In case of extensive fungal lesions of the body, it is recommended to use a cream in tubes of 30 g.

The average duration of treatment and the frequency of application of the drug for dermatomycosis of the trunk, shins is 1 week 1 time per day; with dermatomycosis stop - 1 week 1 time per day; with keratinization, cracks, itching and flaky skin caused by foot fungus - 2 weeks 1-2 times a day; with candidiasis of the skin - 1-2 weeks 1-2 times a day; with colored lichen - 2 weeks 1-2 times a day.

Reducing the severity of clinical manifestations is usually noted in the first days of treatment. If there is an irregular application or premature discontinuation of treatment, there is a risk of renewal of the infection. If there are no signs of improvement, the diagnosis should be verified after 1-2 weeks of therapy.

Lamisil cream is not recommended for use in children under 12 years of age.

Pills

Adults appoint 250 mg once a day.

The recommended duration of treatment for foot dermatomycosis (interdigital, plantar or socks) is 2-6 weeks; at a dermatomymosis of a trunk, anticnemions - 2-4 weeks; with candidiasis of the skin - 2-4 weeks.

Complete disappearance of the manifestations of infection and complaints associated with it can occur only a few weeks after mycological cure.

The recommended duration of treatment for mycosis of the scalp is 4 weeks. Mycoses of the scalp are mainly seen in children.

With onychomycosis (nail fungus), the duration of effective treatment is in most patients from 6 to 12 weeks. With onychomycosis, brushes in most cases are sufficient for 6 weeks of treatment. With onychomycosis of feet, in most cases, 12 weeks of treatment are sufficient. Some patients who have a reduced rate of nail growth may need longer treatment. The optimal clinical effect is observed several months after mycological cure and discontinuation of therapy. This is determined by the time period that is necessary for the growth of a healthy nail.

Solution

The drug is applied externally, once.

For adults and adolescents over the age of 15 years, Lamizil Uno film-forming solution is applied 1 time on both feet, even if the fungal lesion is observed only on one foot. This ensures the destruction of fungi (dermatophytes), which can be located on the foot areas where lesions are visually invisible.

Before applying the product, you should wash and dry your feet and hands.First, one stop is processed, then the other. When starting the procedure on the interdigital areas, a thin layer should be applied evenly between the fingers and around all over their surface, as well as on the sole and sides of the foot to a height of up to 1.5 cm. Use a sufficient amount of the drug to cover the necessary surface of the skin, usually 1/2 tubes for processing each foot.

In the same way, another foot should be treated, even if the skin on it looks healthy. Dry the solution for 1-2 minutes before film formation. After finishing stop treatment, you should wash your hands.

Do not apply the product again to the treated skin. Lamizil Uno should not be rubbed into the skin.

Gel

Lamizil Dermgel is used externally in adults and children from 12 years 1 time per day for any of the indications. Before using the drug, it is necessary to thoroughly clean and dry the affected areas. The drug is lightly rubbed into the areas of both affected and adjacent intact skin. In the case of infections accompanied by intertrigo (under the mammary glands, between the fingers, in the gluteal and groin folds), the gel application area can be covered with gauze, especially at night.

Duration and frequency of application of Lamizil Dermgelya with dermatomycosis of the trunk, shins - 1 week, 1 time per day; with dermatomycosis stop - 1 week, 1 time per day; with multi-colored lichen - 1 week, 1 time per day.

Before the first use of Dermgel Lamizil, the sealing membrane should be punctured using a tip located on the outside of the screw cap.

When using Lamizil Dermgelya, the decrease in the severity of clinical manifestations is usually noted in the first days of treatment. In case of irregular treatment or premature termination, there is a risk of recurrence of the infection. In the event that after a week of treatment there are no signs of improvement, the diagnosis should be verified.

Side effect

• redness;
• sensation of itching or burning;
• allergic reactions.

Contraindications

• increased sensitivity to terbinafine or to any of the inactive ingredients that make up the drug.

Application in pregnancy and lactation

Clinical experience of application of Lamizil for external use in pregnancy is limited, so the drug can be used only on strict indications.

It is known that terbinafine is excreted in breast milk.However, when used in nursing mother Lamizila, any negative effect on the baby is unlikely, since systemic absorption of terbinafine through the skin with external application is negligible.

In experimental studies teratogenic properties of terbinafine have not been revealed. To date, no developmental deficiencies have been reported with the use of Lamizil.

special instructions

Reducing the severity of clinical manifestations is usually noted in the first days of treatment. In case of irregular application or premature termination, there is a risk of recurrence of the infection.

The drug is intended for external use only.

Avoid getting the product into the eyes, as it can cause irritation. In case of accidental contact, the eye should be rinsed immediately with running water, and in case of persistent irritation, consult a specialist.

When developing allergic reactions, it is necessary to cancel the drug.

Drug Interactions

Currently, the drug interaction Lamizil is unknown.

Analogues of the drug Lamisil

Structural analogs for the active substance:

• Atitis;
• Binafin;
• Lamican;
• Lamella;
• Myconorm;
• Mycoterbine;
• Onihon;
• Tebicur;
• Terbized-Aggio;
• Terbisyl;
• Terbiks;
• Terbinafine;
• Terbinafine Hexal;
• Terbinafine Pfizer;
• Terbinafine-MFF;
• Terbinafine-Sar;
• Terbinafine-Teva;
• Terbinox;
• Terbifin;
• Thermic;
• Tigal-sanovel;
• UNOGUSAN;
• Fungoterbine;
• Cidokan;
• Exeter;
• Exifin.

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