Sigetin - instructions for use, reviews, analogs and forms of release (100 mg tablets, injections in ampoules for injection 2 ml) of the drug for the treatment of menopause, postpartum pregnancy, weakness of labor in women. Composition
In this article, you can read the instructions for using the drug Sigetin. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors specialists on the use of Sigetin in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogs Sigetina in the presence of existing structural analogues.Use for the treatment of menopause, endured pregnancy, weakness of labor in women. Composition of the preparation.
Sigetin - in structure has a similarity with synestrol, but does not have an estrogenic effect (similar to the action of female sex hormones-estrogens); at the same time, in connection with the effect on the gonadotropic function of the pituitary gland (the function of the pituitary gland aimed at stimulating the activity of the gonads) and on the functions of the hypothalamus that regulate its function, is effective for mild climacteric disorders. Strengthens the contraction of the uterus, inhibits the gonadotropic function of the pituitary gland, improves placental circulation (fetal circulation, metabolizing between mother and fetus).
Composition
Mesodiethylethylenedibenzenesulfonate + auxiliary substances.
Indications
- climacteric syndrome (manifested by "hot flashes", increased sweating, sleep disorders, irritability, depression, forgetfulness, degenerative changes in the skin and mucous membranes - fragility of the nails, thinning of the skin, wrinkles, dystrophy of the urinary tract mucosa);
- weakness of labor activity;
- intrauterine fetal asphyxia.
Forms of release
Tablets of 100 mg.
Injections in ampoules for injection 2 ml.
Instructions for use and dosing regimen
When a threat of intrauterine asphyxia is administered intravenously, 2-4 ml of 1% solution in 20-40 ml of 40% glucose solution. If necessary, injections are repeated after 30 minutes - 1 hour (no more than 5 times). For the prevention of threatening fetal asphyxia, intramuscularly or intravenously, 1-2 ml of a 1% solution daily for 10 days.
With menopausal disorders, women are given oral tablets at 0,05-0,1 g 2 times a day or intramuscularly 1-2 ml of 1% solution once a day. The course of treatment is 30-40 days.
Side effect
- nausea, vomiting;
- dizziness;
- rash;
- swelling of the eyelids;
- with prolonged use - metrorrhagia (uterine bleeding), cholestatic jaundice (lack of access to bile in the intestine).
Contraindications
- hypersensitivity;
- massive hemorrhage in the parturient woman;
- premature detachment of the normally located placenta.
Carefully
- kidney failure;
- abnormal liver function;
- hyperlipoproteinemia (a violation of lipid metabolism with an increase in the amount of fat in the blood).
Application in pregnancy and lactation
During pregnancy and lactation, Syegin is not used.
special instructions
Not indicated.
Drug Interactions
Strengthens the action of diuretic, antiarrhythmic, antihypertensive drugs, anticoagulants. Weakens the effects of male sex hormones.
Folic acid and thyroid drugs increase the effectiveness of Sigetin.
Analogues of medicinal product Sigetin
Structural analogs for the active substance:
- Sagenite.
Analogues on the pharmacological group (hormones of the hypothalamus, pituitary, gonadotropins and their antagonists):
- Adiurecrin;
- Alterpur;
- Antiqua;
- Atosiban;
- The biosome;
- Bravelle;
- Buserelin;
- Vasomyrin;
- Vero-Danazol;
- Genotropin;
- Genfastat;
- Goserelin;
- Danoval;
- Dianodiol;
- Danol;
- Decapeptil;
- Desmopressin;
- Gentropine;
- Dinatrop;
- Diferelin;
- Zoladex;
- Luveris;
- Lucrin;
- Menogon;
- Menopur;
- Meriofert;
- Metrodine;
- Mininin;
- Modastatin;
- Nativa;
- Norditropin;
- Norprolac;
- Nurem;
- Ovitrel;
- Oxytocin;
- Octreotide;
- Octretex;
- Omnitrop;
- Organutran;
- Pabal;
- Peptorelin;
- Pergoveris;
- Pergonal;
- Pregnil;
- Presinex;
- Profession;
- Pureghon;
- Rastan;
- Remestip;
- Sizen;
- Sandostatin;
- Signyfor;
- Sinakten;
- Somatropin;
- Somatulin;
- Stylamine;
- Tirodzhin;
- Tractocyl;
- Triptorelin;
- Foliotrop;
- Horagon;
- Khoral
- Humatrop;
- Humegon;
- Humog;
- Cetrotid;
- Elonva;
- Emosint.
Response of a gynecologist
Sigetin is an effective drug for alleviating the condition of women during the menopause, as well as for the treatment and prevention of fetal weakness of labor activity accompanied by hypoxia. The drug perfectly helps to eliminate such manifestations of climacteric syndrome as "hot flashes", intense sweating, irritability, forgetfulness, sleep disorders, depressive conditions. Sigetin enhances uterine contractions and promotes increased placental blood flow, which makes it an effective means of preventing intrauterine fetal asphyxia.
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