Pidotimod - instructions for use, reviews, analogs and forms of release (solution for ingestion of 400 mg) drug for the treatment of infections and immunodeficiency in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Pidotimod. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Pidotimoda in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Pidotimod in the presence of existing structural analogs. Use for the treatment of infections and immunodeficiency in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Pidotimod - immunostimulating agent. Pidotimod stimulates and regulates cellular and humoral immunity in conditions of immunodeficiency. The effect on T-cell immunity - increases the activity of natural killers and activates phagocytosis. Effects on humoral immunity - increases the production of cytokines.

Composition

Pidotimod + auxiliary substances.

Pharmacokinetics

When ingested absorption is high. Bioavailability is 45%, half-life is 4 hours. Pidotimod is excreted unchanged in the urine.

The speed and degree of absorption of the pidotimod significantly decreases with simultaneous intake with food. Compared to fasting, the oral bioavailability with food is reduced to 50%, maximum serum concentrations are reached 2 hours later.

Pharmacokinetic studies with elderly patients showed no difference from the pharmacokinetics in adults.

Pidotimod is completely excreted in the urine, the half-life increases with renal failure. Nevertheless, even with severe renal failure, the half-life of the pidotimod does not exceed 8-9 hours.Since patients take the drug every 12 or 24 hours, there is no risk of cumulation in renal failure.

Indications

• immunocorrection in bacterial, fungal and viral infections of the upper and lower respiratory tract;
• immunocorrection in bacterial, fungal and viral infections of the urinary tract.

Forms of release

Solution for oral administration 400 mg.

Instructions for use and dosing regimen

Adults-800 mg twice a day, out of a meal for 15 days.

Children older than 3 years - 400 mg 2 times a day out of a meal for 15 days.

Maximum doses: for adults - 1.6 g per day, for children - 800 mg per day.

Side effect

• allergic reactions;
• nausea;
• diarrhea;
• stomach ache.

Contraindications

• hypersensitivity to the pidotimod;
• intolerance to fructose;
• children under 3 years.

Application in pregnancy and lactation

It is not recommended for use in pregnancy and lactation (breastfeeding). In experimental studies on animals embryotoxic and teratogenic action was not revealed.

Use in children

Contraindicated in childhood up to 3 years.

special instructions

Use with caution in patients with hyperimmunoglobulinemia syndrome E, allergic reactions in the anamnesis.

Drug Interactions

Pidotimod does not bind to blood plasma proteins and is not metabolized, so pharmacokinetic interaction is not expected. Pidotimod can influence the effectiveness of drugs that suppress or stimulate the functional activity of lymphocytes or affect the activity of the immune system.

Analogues of the drug Pidotimod

Structural analogs for the active substance:

• Imunoriks.

Analogues for the pharmacological group (other immunomodulators):

• Aksoglatiran;
• Actinolysate;
• Actipol;
• Aldara;
• Alkimer;
• Anaferon;
• Arbidol;
• Arpefly;
• Arthrofoon;
• Afala;
• Afludol;
• Affinoleukin;
• Bactisporin;
• Bation;
• Beast;
• Bioaron;
• Brizantine;
• Bronho Vaxom;
• Bronhomunal;
• Wartocide;
• Vilozen;
• Wobenzym;
• Galavit;
• Gepon;
• Glatyrate;
• Glutoxim;
• Groprinosin;
• Deoxynate;
• Derinat;
• Dr. Theiss;
• Imiquimod;
• Imichimod;
• Immunal;
• Immunomax;
• Immunorm;
• Imudon;
• Imunofan;
• Ismigen;
• Yodantipyrine;
• Keravort;
• Copaxon;
• Myelopid;
• Mozobail;
• Moliksan;
• Neuroferon;
• Neovastet;
• Nerventra;
• Optinat;
• Panagen;
• Pyrogenal;
• Polymuramyl;
• Polyoxidonium;
• Polyferon;
• Posterizan;
• Profetal;
• Ribomunyl;
• Rhinital;
• Ruzam; Splenin;
• Sporobacterin;
• Stemokin;
• Stimforte;
• Superlimph;
• Tactivin;
• Tamerite;
• Timalin;
• Timexon;
• Timogen;
• Timusamine;
• Trekrezan;
• Tubosan;
• Ferrovir;
• Phlogenzyme;
• Helixor;
• Exalb;
• Epiphamine;
• Erbisol;
• Ergoferon;
• Estifan;
• Echinacecine;
• Echinocor.

Response of infectious diseases physician

Pidotimod is an effective immunostimulating agent. The drug increases the body's resistance to viral, bacterial, fungal infections. I assign it to patients with infections of the upper respiratory tract and infectious diseases of the genitourinary system. Pidotimod helps to speed up recovery with infectious bronchitis, tonsillitis, pharyngitis, bacterial pneumonia. It is also effective in chronic infectious pyelonephritis, cystitis, urethritis of the prostate and bacterial inflammatory pathologies of the vagina.

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