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Lamellar - instructions for use, reviews, analogs and forms of release (spray for external use 1%) drugs for the treatment of fungus or mycosis of the skin, inguinal epidermophytosis and colorful lichen in adults, children and pregnancy. Composition

Lamellar - instructions for use, reviews, analogs and forms of release (spray for external use 1%) drugs for the treatment of fungus or mycosis of the skin, inguinal epidermophytosis and colorful lichen in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Lameler. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Lamitel in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Lamitel's Analogues in the presence of existing structural analogs.Use to treat fungus or mycosis of the skin, inguinal epidermophytosis and colorful lichen in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

 

Lamel - antifungal drug for external use, allylamine derivative with a wide range of antifungal activity. Specifically, it changes the early stage of sterol biosynthesis occurring in fungi. This leads to a deficit of ergosterol and to intracellular accumulation of squalene, which causes death of the fungal cell. The action of Terbinafine (the active substance of the preparation Lamel) is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.

 

In small concentrations, terbinafine has a fungicidal effect against dermatophytes (Trichophyton rubrum, T.mentagrophytes, T.verrucosum, T. violaceum, T.tonsurans, Microsporum canis, Epidermophyton floccosum), moldy (mainly C. albicans) and certain dimorphic fungi ( Pityrosporum orbiculare). Activity with respect to yeast fungi, depending on their type, may be fungicidal or fungistatic.

 

Terbinafine has no effect on the cytochrome P450 system in humans and, accordingly, on the metabolism of hormones or other medications.

 

Composition

 

Terbinafine + excipients.

 

Pharmacokinetics

 

With topical application, absorption is less than 5%, has a minor systemic effect.

 

Indications

  • prevention and treatment of fungal infections of the skin, including mycoses or fungus of feet and hands, fungus of head and beard, fungal lesions of smooth skin of the body caused by dermatophytes such as Trichophyton (including T. rubrum, T. metagrophytes, T. Verrucosum, T. violaceum), Microsporum canis and Epidermophyton floccosum;
  • inguinal epidermophytia;
  • colored lichen;
  • candidiasis of skin and nails.

 

Forms of release

 

Spray for external use 1% in a vial of 20 ml.

 

Instructions for use and dosing regimen

 

Lamella is used externally. Adults and children from the age of 12 spray are applied to the affected areas of the skin (after cleansing and drying) and adjacent areas 1 or 2 times a day in an amount sufficient to thoroughly moisturize. Average duration and frequency of application of the drug: dermatomycosis of the trunk, shins - 1 week, 1 time per day; dermatomycosis stop - 1 week, 1 time per day; multi-colored lichen - 1 week, 2 times a day.

 

Side effect

  • redness at the site of application, a sensation of itching or burning, but these rarely led to the need to stop treatment;
  • allergic reactions (rarely).

 

Contraindications

  • children's age till 12 years;
  • hypersensitivity to the components of the drug.

 

Application in pregnancy and lactation

 

In the experimental studies of teratogenic properties, Lamitel was not identified. Until now, there have been no reports of any developmental defects in the use of the drug. However, because there is no data on the safety of terbinafine during pregnancy, it should be used only on strict indications, when the expected positive effect of treatment for the mother exceeds the potential risk to the fetus.

 

Terbinafine is excreted in breast milk. However, in the case of terbinafine feeding the mother in the form of a spray, only a small amount of active substance is absorbed through the skin, so it is unlikely that the baby will be adversely affected. However, due to the lack of sufficient experience in the use of the drug during breastfeeding, breastfeeding should be discontinued at the time of treatment.

 

Use in children

 

Contraindicated in children under 12 years.

 

Application in elderly patients

 

Dosage regimen in elderly people does not differ from the usual one described above.

 

special instructions

 

Caution should be used Lamellar in persons with hepatic and / or renal insufficiency, alcoholism, oppression of bone marrow hematopoiesis, tumors, metabolic diseases, occlusive diseases of the vessels of the extremities.

 

The drug is intended for external use only. It should be avoided getting on the mucous membrane of the eyes. In case of contact with eyes, rinse with plenty of running water, and in case of persistent irritation, consult a physician. If the drug was accidentally injected into the respiratory tract by inhalation, then, in case of any symptoms, and especially when they are preserved, it is necessary to consult a doctor. When developing allergic reactions, it is necessary to cancel the drug.

 

With care, apply Lamella in the dosage form of the spray to the damaged areas of the skin, since alcohol can cause irritation.

 

Reduction in the severity of clinical manifestations of the disease is usually observed in the first days of treatment. In the case of irregular treatment or premature termination, there is a risk of recurrence of the infection.In the event that after a week after the start of treatment there are no signs of improvement, the diagnosis should be verified.

 

When treating Lamitel, general hygiene rules should be followed to prevent re-infection (through underwear, shoes).

 

Drug Interactions

 

When using the drug in the form of a spray, interactions with other medicinal products are unknown.

 

Analogues of the drug Lamel

 

Structural analogs for the active substance:

  • Atitis;
  • Binafin;
  • Lamisyl;
  • Lamican;
  • Lamifungin;
  • Myconorm;
  • Mycoterbine;
  • Onihon;
  • Tebicur;
  • Terbized;
  • Terbisyl;
  • Terbiks;
  • Terbinafine;
  • Terbinox;
  • Terbifin;
  • Thermic;
  • Ungusan;
  • Fungoterbine;
  • Cidokan;
  • Exeter;
  • Exifin.

 

Analogues of Lamitel on the pharmacological group (antifungal agents):

  • Ambiz;
  • Amicon;
  • Ancotyl;
  • Atitis;
  • Batrafen;
  • Binafin;
  • Beefasam;
  • Vfend;
  • VORICOSE;
  • Voriconazole;
  • Gynofort;
  • Griseofulvin;
  • Dactanol;
  • Dactarine;
  • Daphnejin;
  • Dermazol;
  • Zalain;
  • Imidil;
  • Irunin;
  • Itrazole;
  • Itraconazole;
  • Candide;
  • Candisol;
  • Canditral;
  • Ketoconazole;
  • Clotrimazole;
  • Lamisyl;
  • Lamican;
  • Lotrimin;
  • Loceril;
  • Mikonil;
  • Medoflucon;
  • Mycoterbine;
  • Mifungar;
  • Nizoral;
  • Nitrofungin;
  • Nofung;
  • Onihon;
  • Oronazole;
  • He broke the lacquer;
  • Perch;
  • Pimafucin;
  • Procanazole;
  • Rumikoz;
  • Sebosol;
  • Sertamicol;
  • Tebicur;
  • Tecnazol;
  • Terbiks;
  • Faktodin;
  • Flukonorm;
  • Flukoral;
  • Flucostat;
  • Cidokan;
  • Cyclopolis;
  • Ciscan;
  • Ekalin;
  • Exeter;
  • Exoderyl;
  • Exostat;
  • Ecodax;
  • Ecofuqin;
  • Eraksis.

 

A doctor's opinion of a dermatologist

 

Treatment of fungal diseases is always a difficult task. Spray Lamitel copes well with the fungus in cases when the disease is not started. A good effect of the drug gives in the treatment of foot fungus, trunk, brushes. It is not always enough for seven days to use the spray. Sometimes it is necessary to extend the course of treatment to ten days. If the patient is responsible for the treatment and regularly applies Lamitel to the affected and surrounding areas of the skin, there is no recurrence of the disease. There were no adverse reactions to the drug in my practice.

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