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Monural - instructions for use, analogs, reviews and release forms (powder in the form of granules for the preparation of a solution of 2 g and 3 g) of a drug for the treatment of cystitis, urethritis and pyelonephritis in adults, children and pregnancy

Monural - instructions for use, analogs, reviews and release forms (powder in the form of granules for the preparation of a solution of 2 g and 3 g) of a drug for the treatment of cystitis, urethritis and pyelonephritis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Monural. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Monural in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Monural with existing structural analogues. Use for the treatment of cystitis, urethritis and pyelonephritis in adults, children, as well as in pregnancy and lactation.

 

Monural - broad-spectrum antibiotic, a derivative of phosphonic acid, has a bactericidal effect, the mechanism of which is associated with the suppression of the first stage of bacterial cell wall synthesis. It is a structural analogue of pyruvate phosphoenol, enters into a competitive interaction with the enzyme N-acetyl-glucosamine-3-o-enolpyruvyl transferase. As a result, specific, selective and irreversible inhibition of this enzyme occurs, which ensures that there is no cross-resistance to other classes of antibiotics and the possibility of synergism with other antibiotics (synergism with amoxicillin, cephalexin, pipemidic acid is noted in vitro).

 

It is active in vitro against most gram-positive and gram-negative microorganisms. In vitro phosphomycin (the active ingredient of the preparation Monural) reduces the adhesion of a number of bacteria to the epithelium of the urinary tract.

 

Pharmacokinetics

 

After oral administration, it is rapidly absorbed from the digestive tract. When taken in a single dose of 3 g in urine is reached high concentration (from 1053 to 4415 mg / l), 99% bactericidal for most of the usual pathogens of urinary tract infections.It is excreted unchanged by kidneys (up to 95%) with the creation of high concentrations in the urine; about 5% - with bile.

 

Indications

  • acute bacterial cystitis;
  • acute attacks of recurrent bacterial cystitis;
  • bacterial nonspecific urethritis;
  • asymptomatic massive bacteriuria in pregnant women;
  • postoperative urinary tract infections;
  • prevention of urinary tract infection during surgery and transurethral diagnostic studies.

 

Forms of release

 

Powder in the form of granules for the preparation of a solution for oral administration of 2 g and 3 g.

 

Instructions for use and dosing regimen

 

Adults drug prescribed 3 grams 1 time per day. The course of treatment is 1 day. If necessary (with severe or recurrent infections, the elderly) it is possible to re-take the drug at a dose of 3 g after 24 hours.

 

In order to prevent infection of the urinary tract during surgery, transurethral diagnostic procedures, the drug is taken at a dose of 3 g for 3 hours before the intervention and 3 g at 24 hours after the first dose.

 

For children over the age of 5, the drug is prescribed in a dose of 2 g only once.

 

When appointing the drug to patients with renal insufficiency should reduce the dose and increase the interval between doses.

 

Before taking the granules, dissolve in 1/3 cup of water. The drug is taken once a day on an empty stomach 2 hours before or after eating (preferably before going to bed), previously emptying the bladder.

 

Side effect

  • nausea;
  • heartburn;
  • diarrhea;
  • skin rash;
  • allergic reactions.

 

Contraindications

  • severe renal failure (CC <10 mL / min);
  • children's age is less than 5 years;
  • hypersensitivity to the components of the drug.

 

Application in pregnancy and lactation

 

The use of the drug during pregnancy and during lactation is possible only if the intended benefit of therapy for the mother exceeds the potential risk of developing teratogenic effects.

 

special instructions

 

When appointing Monural to patients with diabetes should take into account that in 1 package containing 2 g of phosphomycin, contains 2.1 g of sucrose, and in 1 package containing 3 g of phosphomycin - 2. 213 g of sucrose.

 

Drug Interactions

 

With simultaneous use with metoclopramide, a decrease in the concentration of phosphomycin in serum and in urine (this combination is not recommended).

 

Analogs of the drug Monural

 

Structural analogs for the active substance:

  • Urophosfabol;
  • Fosfomycin;
  • Phosphomycin sodium;
  • Phosphomycin trometamol.

Similar medicines:

Other medicines:
Reviews (15):
Guests
Alina
Late in the autumn it was frozen waiting for the transport at the stop, as a result, all the rest of the cold came home. Although I tried to warm myself with hot tea and under a rug, but my bladder still chilled and at night the cystitis twisted me like it usually does. Previously slept furaginom, but the effect had to wait a long time, and then the familiar urologist sub-advised a new medicine (for me so sure) monural.

The medicine was not cheap in convenient bags for dissolution in water. But the effect from the reception felt immediately - within an hour or two the symptoms subsided and the pain went away and I forgot about my cystitis. It's better for me than drinking a pack of furagin tablets as it was before.
Guests
Ilona
If I drink anti-aging, can I drink mono?
Administrators
admin
Ilona, In the instructions for the use of Monural there are no indications for interaction with contraceptives. Perhaps for a full backup it is worth to look at the interaction with the medications of your contraceptive and if there is no indication for Monural to take it together. In general, such questions are resolved by a doctor who prescribes the drug, which in turn is worth telling about all the drugs that you are taking at the moment.
Visitors
JuliaS
In general, I believe that first and foremost you need to run to the doctor. I caught a cold at my grandmother's summer cottage that summer and earned myself cystitis. It was treated longly and Monuralom too tried or tasted but nothing helped or assisted.
Visitors
Kara
There was a cystitis. Very cold at night, when frosts were given! The doctor recommended Monural. I drank it. Two days the temperature was from 37.3 to 37.8. I lay, thought everything. And then everything went by as it was taken off by hand. I went to work and forgot that I had cystitis. Think for yourself.I happened to be like the two sides of the coin.
Visitors
bol`noi
The girls say, you chose the Monural yourself or you were prescribed by the doctor. Could I buy it in a pharmacy without a doctor's discharge?
Administrators
admin
bol`noi, Monural is a good uroantibiotic and like any antibiotic is dispensed by prescription. From cystitis, he also helps well (remembering your story with this disease from other issues).
Guests
Julia1981
Monural is excellent for cystitis helps, because it is for this purpose is intended, its action is directed at what would kill the E. coli, which causes an infection. And here to antibiotics of a wide spectrum of action at the majority of people already stability was developed, therefore the probability is great, that they any more will not help or assist at a cystitis.
Guests
Fariza
While waiting for her bus in the winter - very much frozen, especially the legs. After 2-3 days, cystitis with a large amount of excretion appeared, a small one could not walk at all. My friend advised Monural. After reception all as a hand has removed or has taken off. Thank God he helped me winked I advise feel
Visitors
Pavel65
Question to the doctor: Cystitis. I accepted the Monural. It was taken off immediately, but a few days later it returned. STDs are excluded by analysis. The question is - as I understand the monoral acts not through blood, but through urine. Therefore, is it possible for men to have an infection in the prostate and is the monural less effective? Or this is nonsense. And does it make sense to repeat or better to try something else? Thank you.
Administrators
admin
Pavel65, I understand it is treated yourself, therefore, and cystitis may not be cystitis, I fully admit prostatitis, and these are different diseases and are treated differently. It is necessary to go to the urologist and pass urine and blood tests to begin with, so that there is something to talk about with the doctor. Monural and with male cystitis will help and the prostate has nothing to do with it. It is possible that you will need a course of antibiotic treatment, but since the symptoms are not indicated, then there is nothing to talk about, as the question without details.
Guests
Tatyana
An excellent product. I have already won more than once. Cystitis fights well and quickly. Take too nice, because. has orange flavor.
Visitors
Elena06
Hello. Tell me, please, whether it is possible to replace Monural Furagin? At mum a polyneuropathy (lays already 4 years). Ultrasound revealed acute cystitis. Her therapist appointed Tsifran first, then the urologist put the catheter (because urine ceased to go away at all) and said to drink Furagin. The temperature jumps (that is 36.5, then 37.4-37.8). The pain intensifies and has already passed from the bottom of the abdomen to the ribs and back, and numbness of the arms and neck has also intensified. In the side effects indicated: the development of polyneuritis. I read on the Internet, what is it and was horrified. The urologist said that the bladder does not have anything to do with it, and consult the therapist with pain. It turns out that this Furagin strengthens my mother's disease - polyneuropathy, and pain pains in addition. The urologist does not even listen to everything I'm describing to him - he has one answer. I, after reading reviews about Monural, decided to mother no longer give Furagin, and try Monural (there and pobochki less, and it's not so terrible). Mama can not drink a lot of water, but with Furagina one should drink a lot. Force I can not pour it. In addition, urine, like, goes into the urine receiver. Still drunk Kanefron and now has still bought or purchased to mum Tsiston.Prompt, if to drink Monural, that, I so have understood, it is a single dose? And for the elderly, maybe 2g.? Her weight: 38 kg., Age: 70 years.
Administrators
admin
Elena06, For the elderly, there is no need to reduce the dosage of Monural, therefore it is necessary to take the prescribed 3 grams once. In general, the tactics of treatment should still be discussed with the attending physician, because it is a severe patient lying down, plus a bunch of concomitant diseases, so you are responsible for the result. I admit that polyneuropathy in this case can develop as an independent disease, and not as a result of taking Furagin. Although the place of the urologist, I would replace the problem drug with Monural, if it is not contraindicated to a particular patient for the concomitant diseases and there are reasons to prescribe it (that is, acute cystitis).
Guests
Olga
Olga, Your feedback has been moved to the Cyston drug, where it is more appropriate.
admin

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