Pantogam - instructions for use, reviews, analogs and forms of release (tablets 250 mg and 500 mg, capsules 200 mg and 300 mg active, syrup 10%) of the drug for treatment of cerebral palsy in adults, children (including newborns) and in pregnancy
In this article, you can read the instructions for using the drug Pantogam. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Pantogam in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Pantogam in the presence of existing structural analogues. Use to treat cerebral palsy and encephalopathy in adults, children (including infants and newborns), as well as during pregnancy and lactation.
Pantogam - Nootropic preparation.The spectrum of Pantogam's action is related to the presence in its structure of gamma-aminobutyric acid (GABA). The mechanism of action is due to the direct influence of Pantogam on the GABAB-receptor-channel complex.
The drug increases the resistance of the brain to hypoxia and the effects of toxic substances, stimulates anabolic processes in neurons, has an anticonvulsant effect, reduces motor excitability. Pantogam combines a moderate sedative effect with a mild stimulating effect. Increases mental and physical performance. Promotes the normalization of GABA metabolism in chronic alcohol intoxication and the subsequent abolition of ethanol (alcohol). Inhibits the acetylation reactions involved in the mechanisms of inactivation of novocaine and sulfonamides, which allows prolonging the action of the latter.
It causes inhibition of the pathologically increased vesicle reflex and detrusor tone.
Pharmacokinetics
Pantogam quickly absorbed from the digestive tract. The greatest concentrations are created in the liver, kidneys, in the wall of the stomach, in the skin. Penetrates through the BBB. It is not metabolized. It is excreted unchanged for 48 hours. 67.5% of the accepted dose is excreted by the kidneys, 28.5% - with feces.
Indications
- various forms of infantile cerebral palsy;
- children with perinatal encephalopathy from the first days of life;
- mental retardation of varying severity, incl. with behavioral disorders,
- violations of the psychological status of children in the form of a general delay in mental development, specific speech disorders, motor functions and their combination, the formation of school skills (reading, writing, counting, etc.);
- hyperkinetic disorders (including hyperactivity disorder with attention deficit);
- neuro-like conditions (with stuttering, tics of predominantly clonic form, inorganic encopresis and enuresis);
- reduction of mnestiko-intellectual productivity due to arteriosclerotic changes in cerebral vessels, with initial forms of senile dementia, organic brain lesions of traumatic, toxic, neuroinfectious genesis;
- schizophrenia with cerebral organic insufficiency (as part of complex therapy in combination with psychotropic drugs);
- extrapyramidal disorders in organic brain diseases (including myoclonic epilepsy, Huntington's chorea, hepatolenticular degeneration, Parkinson's disease), as well as for the treatment and prevention of extrapyramidal syndrome caused by the administration of neuroleptics;
- epilepsy with a slowing of mental processes and a decrease in cognitive productivity (in combination with anticonvulsants);
- psycho-emotional overload, decreased mental and physical performance, to improve concentration and memorization;
- neurogenic disorders of urination (pollakiuria, imperative urges, mandatory urinary incontinence).
Forms of release
Tablets 250 mg and 500 mg.
Capsules 200 mg and 300 mg Pantogam Active.
Syrup 10%.
Instructions for use and dosage
Pills
Pantogam is taken orally 15-30 minutes after eating.
For adults, the single dose is 0.25-1 g, the daily dose is 1.5-3 g.
For children, a single dose is 0.25-0.5 g, daily - 0.75-3 g.
The course of treatment is 1-4 months, sometimes up to 6 months. In 3-6 months. you can conduct a second course of treatment.
With epilepsy (in combination with anticonvulsants), the drug is prescribed in a dose of 0.75 g to 1 g per day. The course of treatment is up to 1 year or more.
With extrapyramidal neuroleptic syndrome (in combination with the therapy), the dose is up to 3 g per day. Treatment is carried out for several months.
With extrapyramidal hyperkinesias, patients with hereditary diseases of the nervous system (in combination with the therapy administered) are prescribed from 0.5 g to 3 g per day. The course of treatment - up to 4 months or more.
At the consequences of neuroinfections and craniocerebral injuries - 0.25 g 3-4 times a day.
To restore working capacity under increased loads and asthenic conditions, Pantogam is prescribed to 0.25 g 3 times a day.
For the treatment of extrapyramidal syndrome caused by the intake of neuroleptics, adults - 0.5-1 g 3 times a day, children - 0.25-0.5 g 3-4 times a day. The course of treatment is 1-3 months.
At ticks to children - 0.25-0.5 g 3-6 times a day for 1-4 months, adults - 1.5-3 g per day for 1-5 months.
For violations of urination, adults are prescribed a drug at a dose of 0.5-1 g 2-3 times a day. Children - 0.25-0.5 grams daily dose is 0.025-0.05 g / kg. The course of treatment is 1-3 months.
Children with different pathologies of the nervous system depending on the age of the drug are recommended in a dose of 1-3 g. The tactics of prescribing the drug consists in gradually increasing the dose for 7-12 days, taking in the maximum dose for 15-40 days and gradually reducing the dose for 7-12 days before the complete cancellation of Pantogam. The break between the exchange rate of Pantogam is 1-3 months. (as well as for any other nootropic remedy).
Given the nootropic effect of the drug, it is taken in the morning and afternoon.
Syrup
The course of treatment is 1-4 months, sometimes up to 6 months. In 3-6 months. it is possible to conduct a second course of treatment.
Children with different pathologies of the nervous system, depending on the age, are recommended the following doses:
up to 1 year - 5-10 ml (0.5-1 g)
from 1 year to 3 years - 5-12.5 ml (0.5-1.25 g)
from 3 to 7 years - 7.5-15 ml (0.75-1.5 g)
over 7 years - 10-20 ml (1-2 g)
Tactics of prescribing the drug include increasing the dose for 7-12 days, taking in the maximum dose for 15-40 days and gradually reducing the dose for 7-8 days before the removal of Pantogam. The course of treatment is 30-90 days (for certain diseases up to 6 months and more).
Active Capsules
Inside, 15-20 minutes after meals, 2-3 times a day, preferably in the morning and afternoon.
Capsules 200 mg - 1-4 capsules (0.2-0.8 g). The maximum daily dose is 12 capsules (2.4 g).
Capsules 300 mg - 1-3 capsules (0.3-0.9 g). The maximum daily dose of 8 capsules (2.4 g). The course of treatment is 1-4 months, sometimes up to 6-12 months. After 3-6 months, a repeat course of treatment is possible.
Side effect
- rhinitis;
- conjunctivitis;
- skin rashes;
- insomnia;
- drowsiness;
- noise in the head.
Contraindications
- acute severe kidney disease;
- 1 trimester of pregnancy;
- hypersensitivity to the drug.
Application in pregnancy and lactation
The drug is contraindicated for use in the first trimester of pregnancy.
In experimental studies it was shown that Pantogam does not have teratogenic and embryotoxic effects.
Use in children
Use in children is possible according to the dosing regimen.
special instructions
When developing allergic reactions should cancel the drug or reduce the dose.
With prolonged treatment, simultaneous administration of Pantogam with other nootropic drugs and CNS stimulating agents is not recommended.
Drug Interactions
Pantogam prolongs the action of barbiturates, enhances the effects of anticonvulsants.
When combined, Pantogam prevents side effects of phenobarbital, finlepsin, neuroleptics.
The effect of Pantogam is enhanced when applied simultaneously with glycine, xyliphon.
Pantogam potentiates the action of local anesthetics (novocain).
Analogues of the drug Pantogam
Structural analogs for the active substance:
- Gopantam;
- Hopantenic acid;
- Calcium salt of gopantenic acid;
- Calcium gopentate;
- Pantokaltsin.
Similar medicines:
Other medicines:
- Mikrolaks - instructions for use, reviews, analogs and form of release (solution for enemas) laxative drugs for the treatment of constipation in adults, children (including newborns) and pregnancy
- Ingavirin - instructions for use, reviews, analogs and forms of release (30 mg capsules, 60 mg and 90 mg capsules) for treatment of influenza and ARVI in adults, children and pregnancy. Composition
- Azithromycin - instructions for use, analogs, reviews and release forms (capsules and tablets 250 mg and 500 mg) drugs for the treatment of angina, pneumonia and other infections in adults, children and pregnancy