Begrivac - instructions for use, analogs, reviews and release forms (vaccine in the form of a suspension for injections in syringes) of a drug for the treatment and prevention of influenza in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Begrivac. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of experts on the use of Begrivac in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogs of Begrivac with available structural analogues. Use for the treatment and prevention of influenza in adults, children,as well as during pregnancy and lactation. Composition of the preparation.

Begrivac - forms a high specific immunity against influenza. Protective titers of antibodies to influenza viruses after vaccination of persons of different ages are determined in 75-92% of vaccinated.

Composition

Hemagglutinin and influenza A neuraminidase (strain H1N1) + Hemagglutinin and influenza A neuraminidase (strain H3N2) + Hemagglutinin and influenza virus type B + neuraminidase.

Indications

Prevention of influenza in adults and children older than 6 months, including when:

• diseases of the respiratory system and cardiovascular system;
• chronic renal failure;
• diabetes mellitus;
• immunodeficiency, including HIV infection, malignant blood diseases;
• concomitant therapy with immunosuppressants, cytostatics, high doses of HCC;
• radiation therapy;
• for elderly patients (over 65 years);
• for pregnant women at high risk of influenza.

Forms of release

Vaccine in the form of a suspension for injections in syringes 0.5 ml in 1 dose.

Instructions for use and dosing regimen

Intramuscularly, into the deltoid muscle or deeply subcutaneously into the upper third of the outer surface of the shoulder,children of younger age - in the anterolateral surface of the thigh.

Children from 6 months to 3 years: 0.25 ml once. In the event that children who have not previously had the flu and unvaccinated - twice with an interval of 4 weeks.

Children older than 3 years and adults - 0.5 ml once.

Patients with immunodeficiency can enter the vaccine twice in 0.25 ml at intervals of 4 weeks.

Side effect

• headache;
• hyperthermia (fever);
• malaise;
• fatigue;
• shiver;
• sweating;
• soreness in the muscles and joints;
• neuralgia;
• thrombocytopenia (decrease in the number of platelets);
• paresthesia (sensitivity disorder: tingling, burning, crawling crawling);
• convulsions;
• encephalomyelitis (inflammation of the brain and spinal cord of toxic-allergic or viral etiology);
• neuritis (inflammation of the peripheral nerves);
• hyperemia (redness), densification, swelling and tenderness at the site of administration;
• ecchymosis (hemorrhages in the skin or mucous membranes).

Contraindications

• hypersensitivity, including the chicken protein and aminoglycosides;
• allergic reactions to the previous administration of the vaccine;
• acute febrile conditions or exacerbation of a chronic disease (vaccination is carried out after recovery or remission);
• non-severe ARVI (vaccination is performed after normalization of body temperature).

Application in pregnancy and lactation

Preclinical studies have shown that the vaccine Begrivac does not have embryotoxic and teratogenic effects. The decision on vaccination of pregnant women should be taken by a doctor individually, taking into account the risk of infection with influenza and possible complications of influenza infection. Vaccination is most safe in the second-third trimesters of pregnancy. Begrivac does not have teratogenic and toxic effects on the fetus. Possible vaccination during lactation.

Use in children

Allowed the use of Begrivac for children from 6 months of age.

special instructions

Vaccination is carried out annually in the autumn-winter period. It is possible to vaccinate at the beginning of an epidemic rise in the incidence of influenza.

Intravenous administration is not allowed.

Against the background of severe ARVI, acute intestinal diseases and other vaccinations are carried out after the normalization of body temperature.

On the day of vaccination, the vaccinated should be examined by a physician (paramedic) with obligatory thermometry. At a body temperature above 37 degrees Celsius, there is no vaccination.

The vaccination rooms should have medicines for anti-shock therapy (epinephrine, GCS and others).

After vaccination, it is possible to obtain false positive results of serological tests for enzyme-linked immunosorbent assays, which are caused by the production of IgM.

The drug may contain trace amounts of gentamicin.

The vaccinated should be monitored by a health worker within 30 minutes after immunization.

The vials are opened and the vaccination procedure is carried out with strict adherence to aseptic and antiseptic rules: before opening the ampoule, the ampulla neck is wiped with cotton wool soaked with 70% ethanol, the ampoule is opened, the vaccine is taken into a disposable syringe and excess air is removed from the syringe. Ethanol (medical alcohol) rubs the skin at the injection site.

The drug in the opened ampoule is not subject to storage.

The preparation is not suitable for use in ampoules with broken integrity or marking, with a change in physical properties (color, transparency), expired,when the requirements for storage conditions are violated.

Impact on the ability to drive vehicles and manage mechanisms

Does not affect the ability to concentrate and the speed of the psychomotor reaction.

Drug Interactions

The Begrivac vaccine can be used concomitantly with other inactivated vaccines (contraindications to each of the vaccines used must be taken into account, drugs must be injected into different parts of the body, with different syringes).

GCS (glucocorticosteroids) and immunosuppressants reduce the immune response to the administration of the vaccine.

Analogues of the medicament Begrivac

Structural analogs for the active substance:

• Agrippal S1;
• Vaxigrip;
• Grippovac;
• Inflexal;
• Microflu;
• Pandeflu;
• Sovirnipp;
• Ultrix;
• Fluuarix;
• Fluvaxin.

Response of a therapist

Vaccine Beggivac is a reliable preventative against influenza. I recommend it to all my patients. There are few contraindications to the vaccine, side effects after administration are rare. Begrivac is suitable for vaccinating small children, starting at 6 months of age. It can be used for the prevention of influenza in pregnant and lactating women, as well as in people over 65 years of age.Vaccination is usually carried out in the autumn-winter period annually, but it is allowed to be carried out at the very beginning of the epidemic rise in the incidence.

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