Mebrogroline - instructions for use, reviews, analogs and formulations (tablets and pills 50 mg and 100 mg) of the drug for the treatment of allergies, asthma, eczema, urticaria, allergic rhinitis, neurodermatitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Mebrogroline. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Mebogidolin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Mebhydroline in the presence of existing structural analogs.Use for the treatment of allergies, bronchial asthma, eczema, urticaria, pruritus, allergic rhinitis, neurodermatitis, insect bites in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Mebhydrogen - blocker of histamine H1 receptors, ethylenediamine derivative. Has antiallergic, antipruritic, antiexudative, and also weak sedation. It has m-cholinoblocking properties.

Composition

Mebydrolin + auxiliary substances.

Pharmacokinetics

After oral administration, it is rapidly absorbed from the gastrointestinal tract (GIT). Bioavailability is 40-60%. Virtually does not penetrate the blood-brain barrier (BBB). Metabolised in the liver by methylation. Causes the induction of microsomal liver enzymes. It is excreted by the kidneys.

Indications

• hay fever;
• hives;
• eczema (acute or chronic non-contagious inflammatory skin disease characterized by a variety of rashes, burning sensation, itching and a tendency to relapse);
• neurodermatitis (a skin chronic disease of a neurogenic-allergic type, taking place with periods of remission and exacerbation);
• itching;
• allergic rhinitis caused by the pollen of plants;
• other allergic rhinitis, including year-round allergic rhinitis;
• acute atopic (allergic) conjunctivitis;
• skin reaction after an insect bite;
• bronchial asthma (as part of combination therapy).

Forms of release

Tablets of 50 mg and 100 mg.

Dragee 50 mg and 100 mg.

Instructions for use and dosing regimen

Tablets and dragees Mebhydrolyn is taken orally, without chewing, with food or immediately after eating.

Adults and children over 10 years of age - 100-300 mg per day for 2-3 doses. Maximum doses for adults: single dose - 300 mg, daily - 600 mg.

The daily dose for children aged 5-10 years is 100-200 mg; 2-5 years - 50-150 mg; up to 2 years - 50-100 mg.

The duration of the course of treatment is determined by the nature of the disease and the therapeutic effect achieved.

Side effect

• heartburn;
• nausea;
• dry mouth;
• stomach ache;
• dizziness;
• paresthesia (a type of sensitivity disorder characterized by sensations of numbness, tingling sensations, crawling crawling);
• increased fatigue;
• tremor (rapid, rhythmic movements of limbs or trunk caused by muscle contractions);
• drowsiness;
• granulocytopenia, agranulocytosis;
• dysuria (violation of the process of urination).

Contraindications

• hypertrophy (increase in body volume and mass) of the prostate;
• angle-closure glaucoma;
• peptic ulcer of the stomach and duodenum;
• inflammatory diseases of the digestive tract in the phase of exacerbation;
• hypersensitivity to mebrogrolin;
• pyloric stenosis (narrowing of the opening leading from the stomach into the duodenum);
• epilepsy;
• disorders of the heart rhythm (having a vagolytic effect, can improve atrioventricular conductivity and contribute to the development of supraventricular arrhythmias);
• lactose intolerance;
• deficiency of lactase;
• glucose-galactose malabsorption;
• pregnancy, lactation (breastfeeding).

Application in pregnancy and lactation

Mebydrolin is contraindicated for use during pregnancy and during breastfeeding. If you need to use the drug during lactation at the time of treatment should stop breastfeeding.

Use in children

At appointment to children it is necessary to strictly observe an age dosage.

It should be remembered that in children with Mebidrolina reception, paradoxical reactions can develop in the form of increased excitability, irritability, tremor, and sleep disturbances.

special instructions

Use with caution in hepatic and / or renal failure (dosage and interval between doses may be required).

Impact on the ability to drive vehicles and manage mechanisms

During the treatment period, one should refrain from engaging in potentially dangerous activities requiring increased attention and speed of psychomotor reactions (driving vehicles or working with mechanisms).

Drug Interactions

Mebhydroline increases the effect of sedatives and ethanol (alcohol).

Analogues of the medicinal product Mebhydrogen

Structural analogs for the active substance:

• Diazoline;
• Diazolin powder;
• Mebhydroline Napadisylate.

Analogues of Mebhydrolyn by pharmacological group (H1-antihistamines):

• Aviamarin;
• Alerza;
• Alestamine;
• Allegra;
• Allergodyl;
• Allergoferon;
• Allertec;
• Astemizole;
• Betadrin;
• Bonin;
• Bronal;
• Vibrocil;
• Visallergol;
• Gismanal;
• Histaglobin;
• Histalong;
• Histafen;
• Histimet;
• Glencet;
• Dezal;
• Desloratadine;
• Diazoline;
• Diphenhydramine;
• Dimista;
• Dramina;
• Zincet;
• Zirtek;
• Zodak;
• Kestin;
• Claritin;
• Clarifer;
• Cold storage;
• Koldar;
• Xizal;
• Levocetirizine;
• Lethisen;
• Loratadine;
• Lordestin;
• Mibyron;
• Nixar;
• Has occluded;
• Orinol;
• Pipolphen;
• Polynadym;
• Primalan;
• The Raslip;
• Rivtagil;
• Rupafin;
• Semprex;
• Ciel;
• Sowentol;
• Suprastin;
• Tavegil;
• Tyrror;
• Trexile;
• The fexophagus;
• Femizol;
• Fenistil;
• Fenkarol;
• Chloropyramine;
• Cetirizine;
• Cetrin;
• Ezlor;
• Erespal;
• Erius;
• Erolin;
• Espa Bastin.

A doctor's opinion of a dermatologist

Mebhydrogen is a good effective antiallergic drug. I assign it to my patients (children and adults) with hives, neurodermatitis, eczema. There were no side effects on it in my practice. Mebhydrogen copes well with skin itching and reduces swelling of tissues. It is important (and this is noted by all patients) that he has virtually no sleeping pills. The drug is also popular because of its low cost, since not all patients can afford to buy expensive antiallergic drugs.

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