Skinoren - instructions for use, reviews, analogs and formulations (gel 15%, cream or ointment 20%) drugs for the treatment of acne, acne, and hyperpigmentation spots on the skin in adults, children and pregnancy

In this article, you can read the instructions for using the drug Skinoren. There are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of Skinoren in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Skinorena in the presence of existing structural analogues. Use for the treatment of acne (acne), rosacea and hyperpigmentation spots on the skin in adults, children, as well as during pregnancy and lactation.

Skinoren - a drug for the treatment of acne.Azelaic acid (the active ingredient of Skinoren) normalizes the disturbed processes of keratinization in the follicles of the sebaceous glands, reduces the content of free fatty acids in the lipids of the skin and reduces its fat content. It shows antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis. Anti-inflammatory effect is also caused by a decrease in neutrophil metabolism and a decrease in the production of free radical forms of oxygen. Azelaic acid has a dose and time-dependent inhibitory effect on the growth and viability of abnormal melanocytes.

Pharmacokinetics

After application to the skin, Skinoren is practically not absorbed into the systemic bloodstream (no more than 3.6% when applying 5 g of gel or cream). Part of the absorbed azelaic acid is excreted by the kidneys unchanged, and the part in the form of dicarboxylic acids (C5, C7), formed from azelaic acid as a result of beta oxidation.

Indications

• acne vulgaris;
• hyperpigmentation, incl. melasma, chloasma (for cream);
• rosacea (for the gel).

Forms of release

Gel for external use 15%.

Cream or ointment for external use 20%.

Instructions for use and how to use them

The dosage regimen and the duration of therapy are set individually.The drug is prescribed for adults and children over 12 years.

Before applying the product, the skin should be cleaned with water or a mild cleansing cosmetic, then dried.

Cream or gel applied to the affected areas of the skin evenly thin layer 2 times a day (morning and evening) and lightly rub. The drug should be used in sufficient quantities, but not excessively (approximately 2.5 cm is sufficient for the entire surface of the face). The drug should be used regularly throughout the course of treatment, the duration of which depends on the clinical picture of the disease and the severity of the symptoms. With acne vulgaris (acne vulgaris), the improvement is usually observed after 4 weeks. To obtain the best results, the drug should be continued for several months. Additional protection of the skin from UV radiation during the treatment of acne is not required.

With melasma, the drug is used as a cream. The minimum duration of therapy is 3 months, for best results, Skinoren cream should be used regularly. During the entire period of melasma therapy, sunscreens (UVB and UVA) must be used,to prevent the exacerbation of the disease caused by exposure to the sun and / or the re-pigmentation of the clarified areas.

Side effect

• local irritation, manifested in the form of hyperemia, peeling, erythema, burning, itching;
• skin allergic reactions (rash).

Contraindications

• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

Use during pregnancy and lactation is possible after consultation with a doctor, however, it should be avoided applying it to the area of ​​the mammary glands before feeding.

special instructions

In cases of skin irritation, the amount of a single application of a gel or cream should be reduced or the frequency of application of the drug reduced to 1 time per day; if necessary, a short-term drug cancellation (for several days).

Avoid contact with the eyes and wound surfaces; In case of accidental contact, flush immediately with water.

Additional skin protection from UV radiation during treatment with Skinoren is not required.

Epidermal and mixed epidermal-dermal types of melasma are well suited to therapy with Skinoren cream. Skinoren cream is not effective for dermal melasma.For differential diagnosis it is recommended to use a Wood lamp.

Drug Interactions

The interaction of Skinoren with other medications has not been revealed to date.

Analogues of Skinoren

Structural analogs for the active substance:

• Azelaic acid;
• Azelik.

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