Novitropan - instructions for use, reviews, analogs and formulations (5 mg tablets) of the drug for the treatment of urinary incontinence, nocturnal enuresis, neurogenic bladder in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Novitrothane. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Novirtropane in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Novitropane in the presence of existing structural analogues.Use for the treatment of urinary incontinence, nocturnal enuresis, neuromuscular dystrophy of the bladder, neurogenic bladder in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Novitrothane m-cholinoblocker from the group of tertiary amines. Along with moderate m-holinoblokiruyuschey activity has the ability to directly affect the smooth muscles of internal organs (myotropic antispasmodic effect). Eliminates spasms and lowers the tone of smooth muscles of the internal organs: the gastrointestinal tract (GIT), bile ducts, uterus, urinary tract, including the bladder. With a neurogenic bladder, oxybutynin (Novitropan's active ingredient) relaxes the detrusor (muscle) of the bladder, reduces spontaneous detrusor cuts, increases the capacity of the bladder, and reduces the frequency of urinary urges.

Composition

Oxybutynin hydrochloride + excipients.

Pharmacokinetics

After oral administration, the maximum concentration of drug in the blood is reached after 45 minutes, the concentration value is proportional to the applied dose.

Indications

• urinary incontinence due to unstable bladder function of a neurogenic nature (detrusor hyperreflexion, for example, in multiple sclerosis or spina bifida);
• urinary incontinence of idiopathic nature;
• nocturnal enuresis in children older than 5 years (in the form of monotherapy or in combination with other drugs);
• a neurogenic bladder;
• neuromuscular dysfunction of the bladder.

Forms of release

Tablets 5 mg.

Instructions for use and dosing regimen

Is taken internally. Adults - 5 mg 2-3 times a day. At elderly patients at the beginning of treatment apply 2.5-3 mg 2 times a day, then, if necessary, gradually increase the dose to 5 mg 2 times a day.

Children older than 5 years - the initial dose of 2.5-3 mg 2 times a day, if necessary, gradually increase the dose to 5 mg 2-3 times a day. At night enuresis, the last dose should be taken immediately before bedtime.

Side effect

• dry mouth;
• nausea;
• constipation, diarrhea;
• discomfort in the abdominal region (abdominal region);
• headache, dizziness;
• drowsiness;
• decreased visual acuity.
• dry skin;
• tides (more often in children);
• difficulty urinating;
• retention of urine;
• arrhythmias.

Contraindications

• violation of the outflow of urine from the bladder, when precipitation (precipitation) of delayed urine is possible;
• intestinal obstruction;
• atony (lack of tonus) of the intestine;
• severe ulcerative colitis;
• expansion of the colon;
• myasthenia gravis (muscle weakness);
• glaucoma;
• lactation (breastfeeding);
• children under 5 years;
• hypersensitivity to oxybutynin.

Application in pregnancy and lactation

In pregnancy Novitropan is used only on strict indications, when the expected benefit for the mother exceeds the potential risk to the fetus.

Oxibutinin is contraindicated for use during lactation (breast-feeding).

Use in children

Contraindicated in children under 5 years.

Application in elderly patients

Use with caution in elderly patients.

special instructions

Novitropane is used with caution in elderly patients, with neurocirculatory dystonia (NDC), liver or kidney function disorders, thyrotoxicosis, arrhythmia, coronary heart disease (CHD), chronic heart failure, arterial hypertension, initial manifestations of benign prostatic hyperplasia,ulcerative colitis (NNC), in patients with ileostomy, colostomy, as well as hernia of the esophagus of the diaphragm, accompanied by reflux esophagitis.

Impact on the ability to drive vehicles and manage mechanisms

They are used with caution in patients whose activity requires increased concentration of attention, high speed of psychomotor reactions.

Drug Interactions

When used simultaneously with drugs that have an anticholinergic effect, it can be amplified.

With simultaneous application of Itraconazole increases the concentration of oxybutynin in the blood plasma.

Analogues of Novitropan

Structural analogs for the active substance:

• Driptan;
• Oxybutine;
• Cystrin.

Analogues on the pharmacological group (myotropic antispasmodics):

• Avisan;
• Altalex;
• Bendazole;
• Benzyclan fumarate;
• Vero-Drotaverine;
• Galidor;
• Demidov syrup;
• Demidov elixir;
• Dibazol;
• Dicetel;
• Trust;
• Driptan;
• Droverin;
• Drotaverine;
• Duspatalin;
• Dutan;
• Kellin;
• Librax;
• Marelin;
• Mareni dye extract;
• Mebeverin;
• Mebespalin retard;
• Mint tablets;
• Peppermint peppermint;
• Neobutin;
• Niaspam;
• Nikoshpan;
• But-shpa;
• But-shpa fort;
• Oxybutine;
• Papaverine;
• Papaverine hydrochloride;
• Pinaveria bromide;
• Plantex;
• Platyphylline;
• Platifillin hydrotartrate;
• Ple-Spa;
• Spazmoveralgin Neo;
• Spazmol;
• Spasmodic;
• Spasmonet;
• Spasmonet forte;
• Spasmocystenal;
• Cosporeine;
• Spacock;
• Sparex;
• Talinda retard;
• Trimedate;
• Trimedat Valenta;
• Fennel fruit;
• Cystenal;
• Cystrin;
• Enablex.

Review of the pediatrician

I prescribe Novitropan to adolescents for treatment of nocturnal enuresis in combination with physiotherapeutic procedures, correction of the daily regimen and drinking regimen. In most cases, a positive trend is noted when taking half a tablet (2.5 mg) 3 times a day, with the obligatory condition that the last dose the child takes before bed. There were patients who had to increase the dose to 15 mg per day, that is, 1 tablet 3 times a day. There were no pronounced side effects during treatment with Novitropane in my practice.

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